selfadjoint
@selfadjoint.bsky.social
Libertarian, pozitivist, transhumanist
Reposted by selfadjoint
𝗛𝗼𝘄 𝗱𝗼𝗲𝘀 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝗶𝗺𝗽𝗹𝗲𝗺𝗲𝗻𝘁 𝗱𝗲𝗰𝗶𝘀𝗶𝗼𝗻𝘀 𝗶𝗳 𝘁𝗵𝗲𝗿𝗲 𝗶𝘀 𝗻𝗼 "𝗰𝗲𝗻𝘁𝗿𝗮𝗹 𝗲𝘅𝗲𝗰𝘂𝘁𝗶𝘃𝗲" (𝗮𝗸𝗮 𝗵𝗼𝗺𝘂𝗻𝗰𝘂𝗹𝘂𝘀)?
Via Decision Formation Through Multi-Area Population Dynamics
Excellent short review.
doi.org/10.1523/JNEU...
#neuroskyence
Via Decision Formation Through Multi-Area Population Dynamics
Excellent short review.
doi.org/10.1523/JNEU...
#neuroskyence
November 20, 2025 at 8:37 PM
𝗛𝗼𝘄 𝗱𝗼𝗲𝘀 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝗶𝗺𝗽𝗹𝗲𝗺𝗲𝗻𝘁 𝗱𝗲𝗰𝗶𝘀𝗶𝗼𝗻𝘀 𝗶𝗳 𝘁𝗵𝗲𝗿𝗲 𝗶𝘀 𝗻𝗼 "𝗰𝗲𝗻𝘁𝗿𝗮𝗹 𝗲𝘅𝗲𝗰𝘂𝘁𝗶𝘃𝗲" (𝗮𝗸𝗮 𝗵𝗼𝗺𝘂𝗻𝗰𝘂𝗹𝘂𝘀)?
Via Decision Formation Through Multi-Area Population Dynamics
Excellent short review.
doi.org/10.1523/JNEU...
#neuroskyence
Via Decision Formation Through Multi-Area Population Dynamics
Excellent short review.
doi.org/10.1523/JNEU...
#neuroskyence
Reposted by selfadjoint
This is absolutely ridiculous, would devastate numerous academic fields, and would destroy the lives of people I love very much. Please, please join me in sending a comment in on this telling them so
DHS is proposing a rule that would end "duration of status" for J, F and other visa holders. This would decimate the international graduate student and postdoc population, which are a crucial part of the United States biomedical workforce. There's still time for you to comment on the proposed rule.
Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media
Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...
www.federalregister.gov
September 29, 2025 at 2:55 PM
This is absolutely ridiculous, would devastate numerous academic fields, and would destroy the lives of people I love very much. Please, please join me in sending a comment in on this telling them so
Reposted by selfadjoint
Many of the most complex and useful functions in biology emerge at the scale of whole genomes.
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
September 17, 2025 at 3:03 PM
Many of the most complex and useful functions in biology emerge at the scale of whole genomes.
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
Reposted by selfadjoint
As we get closer to market approval for our breakthrough retinal prosthesis, it's time for a Science patient registry.
If you or a family member have late stage macular degeneration (AMD), retinitis pigmentosa, or Stargardt disease, please consider getting in touch!
science.xyz/news/science...
If you or a family member have late stage macular degeneration (AMD), retinitis pigmentosa, or Stargardt disease, please consider getting in touch!
science.xyz/news/science...
Connecting the Blind to Groundbreaking BCI Vision Restoration Technology Through Science Corporation’s Patient Registry for Retinal Diseases | Science Corporation
Science Corporation is a clinical-stage medical technology company.
science.xyz
September 11, 2025 at 2:54 PM
As we get closer to market approval for our breakthrough retinal prosthesis, it's time for a Science patient registry.
If you or a family member have late stage macular degeneration (AMD), retinitis pigmentosa, or Stargardt disease, please consider getting in touch!
science.xyz/news/science...
If you or a family member have late stage macular degeneration (AMD), retinitis pigmentosa, or Stargardt disease, please consider getting in touch!
science.xyz/news/science...
Reposted by selfadjoint
The sky over my house Wednesday night was wild!
June 6, 2025 at 12:48 PM
The sky over my house Wednesday night was wild!
Reposted by selfadjoint
Amazing mammatus in the sky over my home last night!
June 6, 2025 at 2:45 AM
Amazing mammatus in the sky over my home last night!
Reposted by selfadjoint
I want to remind everyone that without Elon Musk, we wouldn't be in this situation where our academic institutions, science enterprise, and democracy are being dismantled, and millions of additional people around the world are going to die. We want both of them to lose horribly in this fight.
June 5, 2025 at 9:13 PM
I want to remind everyone that without Elon Musk, we wouldn't be in this situation where our academic institutions, science enterprise, and democracy are being dismantled, and millions of additional people around the world are going to die. We want both of them to lose horribly in this fight.
Reposted by selfadjoint
The geoguessing power of o3 is a really good sample of its agentic abilities. Between its smart guessing and its ability to zoom into images, to do web searches, and read text, the results can be very freaky.
I stripped location info from the photo & prompted “geoguess this”
I stripped location info from the photo & prompted “geoguess this”
April 17, 2025 at 4:37 AM
The geoguessing power of o3 is a really good sample of its agentic abilities. Between its smart guessing and its ability to zoom into images, to do web searches, and read text, the results can be very freaky.
I stripped location info from the photo & prompted “geoguess this”
I stripped location info from the photo & prompted “geoguess this”
Reposted by selfadjoint
The incoming NIH Director has repeatedly stressed the importance of open science and open data.
Now petabytes of NIH-hosted research data are about to be lost on his watch.
www.404media.co/nih-archives...
Now petabytes of NIH-hosted research data are about to be lost on his watch.
www.404media.co/nih-archives...
Massive, Unarchivable Datasets of Cancer, Covid, and Alzheimer's Research Could Be Lost Forever
Days before Robert F. Kennedy Jr. announced that 10,000 HHS staffers would lose their jobs, a message appeared on NIH research repository sites saying they were "under review."
www.404media.co
April 5, 2025 at 12:01 AM
The incoming NIH Director has repeatedly stressed the importance of open science and open data.
Now petabytes of NIH-hosted research data are about to be lost on his watch.
www.404media.co/nih-archives...
Now petabytes of NIH-hosted research data are about to be lost on his watch.
www.404media.co/nih-archives...
Reposted by selfadjoint
Today's Headlines
April 3, 2025 at 8:27 AM
Today's Headlines
Reposted by selfadjoint
BREAKING: People are being suspended on X in Turkey for posting videos of these protests against Erdoğan’s corrupt and repressive regime.
Keep sharing everywhere.
Keep sharing everywhere.
March 23, 2025 at 12:20 PM
BREAKING: People are being suspended on X in Turkey for posting videos of these protests against Erdoğan’s corrupt and repressive regime.
Keep sharing everywhere.
Keep sharing everywhere.
Reposted by selfadjoint
The new Defense department budget erases $20 MILLION DOLLARS for pancreatic cancer research. $20,000,000 gone, for a disease with a 5-year survival rate of 13%.
March 22, 2025 at 3:38 PM
The new Defense department budget erases $20 MILLION DOLLARS for pancreatic cancer research. $20,000,000 gone, for a disease with a 5-year survival rate of 13%.
Reposted by selfadjoint
My feed is increasingly looking like the pre-credit montage of headlines in a post apocalyptic action movie.
March 18, 2025 at 12:59 PM
My feed is increasingly looking like the pre-credit montage of headlines in a post apocalyptic action movie.
Reposted by selfadjoint
My talking points in recent interviews, please use as you see fit:
1.Every $1 in NIH funding returns ~$2.50 to the economy.
2.Every $1B in cuts from NIH extramural = 7500 lost employees, just in science.
3.These don't include priceless improvements in health.
1/x
1.Every $1 in NIH funding returns ~$2.50 to the economy.
2.Every $1B in cuts from NIH extramural = 7500 lost employees, just in science.
3.These don't include priceless improvements in health.
1/x
March 12, 2025 at 2:29 AM
My talking points in recent interviews, please use as you see fit:
1.Every $1 in NIH funding returns ~$2.50 to the economy.
2.Every $1B in cuts from NIH extramural = 7500 lost employees, just in science.
3.These don't include priceless improvements in health.
1/x
1.Every $1 in NIH funding returns ~$2.50 to the economy.
2.Every $1B in cuts from NIH extramural = 7500 lost employees, just in science.
3.These don't include priceless improvements in health.
1/x
Reposted by selfadjoint
Wow. "NIH" canceled my co-mentored (with Dave Sulzer) PhD student's F31 funding. His work is on understanding the genetics and neuroscience of language learning disorders. F31 provides no indirect $ to Columbia, just pays his salary. Not that it should matter, but he's an American citizen. W.T.F.
March 11, 2025 at 12:41 PM
Wow. "NIH" canceled my co-mentored (with Dave Sulzer) PhD student's F31 funding. His work is on understanding the genetics and neuroscience of language learning disorders. F31 provides no indirect $ to Columbia, just pays his salary. Not that it should matter, but he's an American citizen. W.T.F.
Reposted by selfadjoint
The largest private employer in Baltimore just lost $800 million in federal contracts and grants. This recession is going to be a doozy.
Johns Hopkins Plans Staff Layoffs After $800 Million Grant Cuts
Local and international health research efforts are already winding down as the university braces for even more potential cuts.
www.wsj.com
March 12, 2025 at 12:09 AM
The largest private employer in Baltimore just lost $800 million in federal contracts and grants. This recession is going to be a doozy.
Reposted by selfadjoint
🚨🧪 Are you a researcher affected by the recent cancellation of federal grants and contracts at Columbia University?
I'm working on a story for @Nature.com. If you want to chat, your identity will be kept private.
Signal: humbertobasilio.24
Email: humberto.basilio@us.nature.com
Repost please!
I'm working on a story for @Nature.com. If you want to chat, your identity will be kept private.
Signal: humbertobasilio.24
Email: humberto.basilio@us.nature.com
Repost please!
March 10, 2025 at 2:38 PM
🚨🧪 Are you a researcher affected by the recent cancellation of federal grants and contracts at Columbia University?
I'm working on a story for @Nature.com. If you want to chat, your identity will be kept private.
Signal: humbertobasilio.24
Email: humberto.basilio@us.nature.com
Repost please!
I'm working on a story for @Nature.com. If you want to chat, your identity will be kept private.
Signal: humbertobasilio.24
Email: humberto.basilio@us.nature.com
Repost please!
Reposted by selfadjoint
Last year, I was overjoyed to receive an NIH NRSA fellowship to study toddler brains and caregiving effects on memory at Columbia. Last night, my grant was terminated.
March 11, 2025 at 3:17 PM
Last year, I was overjoyed to receive an NIH NRSA fellowship to study toddler brains and caregiving effects on memory at Columbia. Last night, my grant was terminated.
Austin TX. Stand up for Sci
March 8, 2025 at 2:06 AM
Austin TX. Stand up for Sci
Reposted by selfadjoint
Many in our group were reluctant, at first, to recommend halting line of basic research. But after considering the unprecedented risks vs minimal benefits, we were unanimous in our recommendation.
That said, we welcome more discussions. We're fortunate that the technology is still a ways off.
That said, we welcome more discussions. We're fortunate that the technology is still a ways off.
Holy crap! The chirality of life jumping from pure research to planet destroying mistake. Once again, one has to ask how and when and why we might halt research into certain questions.
Shareable link to @carlzimmer.bsky.social article in NYTimes on serious concerns over mirror bacteria, published in Science today.
www.nytimes.com/2024/12/12/s...
www.nytimes.com/2024/12/12/s...
December 12, 2024 at 8:10 PM
Many in our group were reluctant, at first, to recommend halting line of basic research. But after considering the unprecedented risks vs minimal benefits, we were unanimous in our recommendation.
That said, we welcome more discussions. We're fortunate that the technology is still a ways off.
That said, we welcome more discussions. We're fortunate that the technology is still a ways off.
Reposted by selfadjoint
Not now Mirror Universe, not now.
December 13, 2024 at 4:23 AM
Not now Mirror Universe, not now.
what a week; huh!
November 25, 2024 at 4:14 PM
what a week; huh!
Reposted by selfadjoint
Post a non-religious photo you think of as holy.
November 23, 2024 at 4:09 PM
Post a non-religious photo you think of as holy.
Reposted by selfadjoint
Wow! Great study. For sure agree with the conclusion, time to get started on clinical trials with Familiar Alzheimer’s. Why not also human trials of P301S #tau mutation associated Frontotemporal Dementia?
Exciting work on Christchurch!
www.cell.com/molecular-th...
www.cell.com/molecular-th...
AAVrh.10 delivery of novel APOE2-Christchurch variant suppresses amyloid and Tau pathology in Alzheimer’s disease mice
Crystal and colleagues develop gene therapy for APOE4-associated Alzheimer’s disease;
humanized APOE4 mouse models with amyloid or tau pathology received AAV expressing
APOE protective variants. The c...
www.cell.com
November 23, 2024 at 9:28 PM
Wow! Great study. For sure agree with the conclusion, time to get started on clinical trials with Familiar Alzheimer’s. Why not also human trials of P301S #tau mutation associated Frontotemporal Dementia?