Sean M. Wu, M.D. Ph.D. FACC FAHA
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seanmwu.bsky.social
Sean M. Wu, M.D. Ph.D. FACC FAHA
@seanmwu.bsky.social
1.9K followers 2.3K following 97 posts
Professor of Medicine/Cardiology, Chief, Basic & Translational Research, Div Of Cardiology, Senior Vice Chair Academic Affairs, Dept of Med, Assoc Director, CV Institute, Stanford Univ. Investigator in Cardiac Development, Regenerative Med, Bioengineering.
Posts Replies Media Videos
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
hanzhumd.bsky.social
It was great working with @seanmwu.bsky.social and @aliraissadati.bsky.social on this seminal work investigating the proof of concept use cell free mRNA biomarkers in ici myocarditis, a technology that can be expanded to other CV diseases! @stanfordmedicine.bsky.social @scvi-mavens.bsky.social
August 18, 2025 at 5:23 PM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
jci.org
Immune checkpoint inhibitors have transformed cancer therapy, but adverse events such as myocarditis remain hard to diagnose.

@aliraissadati.bsky.social @seanmwu.bsky.social & team offer a noninvasive, early-detection tool for ICI-induced myocarditis—plasma cf-mRNA profiling: buff.ly/fVioq2o
September 2, 2025 at 1:20 PM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
jci.org
ICYMI: Immune checkpoint inhibitors have transformed cancer therapy, but adverse events such as myocarditis remain hard to diagnose.

@aliraissadati.bsky.social @seanmwu.bsky.social & team offer a noninvasive, early-detection tool for ICI-induced myocarditis—plasma cf-mRNA profiling: buff.ly/d7GpTU0
September 6, 2025 at 3:33 PM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
aliraissadati.bsky.social
Thrilled to share our work in @jclinical-invest.bsky.social demonstrating the potential of cell free mRNA as a liquid biopsy of myocardial inflammation! Many thanks to my fantastic coauthors and especially my mentor @seanmwu.bsky.social for their unwavering support!
www.jci.org/articles/vie...
JCI - Using plasma cell-free mRNA to profile immune response and myocardial damage in immune checkpoint inhibitor–induced myocarditis
Alireza Raissadati, Xuanyu Zhou, Harrison Chou, Yuhsin Vivian Huang, Shaheen Khatua, Yin Sun, Anne Xu, Sharon Loa, Arturo Hernandez, Han Zhu, Sean M. Wu
www.jci.org
August 15, 2025 at 7:22 PM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
arunsharmaphd.bsky.social
Catching up with @seanmwu.bsky.social lab alumni including @hanzhumd.bsky.social and Soah Lee at #BCVS2025!

Reuniting with old friends is the best part of scientific meetings, other than the science of course! 🔬
July 25, 2025 at 5:27 PM
seanmwu.bsky.social
Keynote speech @ #bcvs2025 by @benoitbruneau.bsky.social @UCSF discussing the regulation of gene expression during ❤️ development, now in 3D! With moderator Jennifer Davis & intro by Farah sheik @americanheart.bsky.social
July 24, 2025 at 3:30 PM
seanmwu.bsky.social
Continuing the tradition of StanfordCVI dinner reception at #bcvs2025 w great presentations from CVI alumni ArunSharma @ Cedar Sinai, Mingtao Zhao @ Cinncinati Childrens, & Instructors David Staudt & Masataka Nishiga (soon 2 be facuty @ OhioState @stanfordcvi.bsky.social @americanheart.bsky.social
July 24, 2025 at 2:52 PM
seanmwu.bsky.social
Opening session of AHA #bcvs2025 w AHA Prez Stacey Rosen, FarahSheikh, Maria Kontariditis, followed by sarcomere structure biology w Stefan Raunser @ Max-Planck Institute Physiology, Michael Greenberg @ WUSTL & JC_Tardiff @ Univ of Az. @americanheart.bsky.social @benoitbruneau.bsky.social
July 23, 2025 at 6:23 PM
seanmwu.bsky.social
Great turnout at AHA #BCVS2025 Early Career Session! The future of basic CV science is bright! Inspiring keynote lecture by David Kass at JohnsHopkins on his career in science. @stanfordmedicine.bsky.social @stanfordcvi.bsky.social @stanforddeptmed.bsky.social
July 23, 2025 at 4:04 PM
seanmwu.bsky.social
Congratulations!!!
arianneinthelab.bsky.social Arianne Caudal, PhD @arianneinthelab.bsky.social · Jul 16
✨ Career update: Thrilled to share that I’ve received an NOA for the NIH K99/R00 Pathway to Independence Award. Thank you to my mentors for your endless support @Joseph_C_Wu @rongtian2.bsky.social @juliaritterhoff.bsky.social @chifungleephd.bsky.social @seanmwu.bsky.social @stanfordcvi.bsky.social
July 18, 2025 at 4:27 AM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
jeremymberg.bsky.social
A short Bluetorial about my early days as the Director of the National Institute of General Medical Sciences (NIGMS) at NIH.

The importance of feeling responsibility and taking pride in doing the best job you can
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
July 6, 2025 at 11:28 AM
seanmwu.bsky.social
Warning-some of you might find it triggering to read the flagrant violation of 1st amendment rights by the government against Harvard. The lawsuit from Harvard today provides a detailed account of what has transpired in the past two months. www.nytimes.com/interactive/...
Read Harvard’s Lawsuit Against Trump (Gift Article)
Harvard University sued the Trump administration after it moved to block international students from enrolling.
www.nytimes.com
May 24, 2025 at 11:59 PM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
baileybowcutt.bsky.social
I'm a current Harvard graduate student and I found out today that I had my NSF GRFP terminated without notification. I was awarded this individual research fellowship before even choosing Harvard as my graduate school
May 22, 2025 at 9:38 PM
seanmwu.bsky.social
Great to see you Jon in Dallas earlier this week! Look forward to catch up again in-person at the BCVS meeting in Baltimore later this July. 👍🙏
jonpheart.bsky.social Jon Pagtakhan @jonpheart.bsky.social · May 15
Successful #AHA Council Operations Committee meeting yesterday, & continued deep strategic planning w/ the one & only BCVS Council Chair Elect @seanmwu.bsky.social Missed fearless leader BCVS Council Chair Dr. Maria Kontaridis!

👉 Join/renew AHA membership! bit.ly/AHAmember
May 18, 2025 at 3:54 AM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
drhelenecollin1.bsky.social
Sign up now if you are in Chicago or surrounding states. Registration $40 for trainees and $75 for faculty.
Great presentations.
Good networking opportunities.
drhelenecollin1.bsky.social Helen Collins @drhelenecollin1.bsky.social · Apr 18
🗣️🗣️calling all cardiovascular researchers in the Chicago area and surrounding states.This one day symposium at Loyola is a great opportunity for trainees and researchers to network, present their research, and hear from the great Dr. Leinwand. 🫀🫀🫀 #cardiosky @barefieldlab.bsky.social
May 10, 2025 at 12:49 AM
seanmwu.bsky.social
Our so called Secretary of Education now writes official letters like Trump writes posts on X and Truth Social. This is the education level we’ll be having across the country once the administration guts all funding for science 2 universities & student support. 🤬🤬🤬
ericcolumbus.bsky.social Eric Columbus @ericcolumbus.bsky.social · May 6
🚨🚨 Deranged letter from Education Secretary Linda McMahon to Harvard’s president, cutting off federal funding for any new grants.

Worth reading in full. It is NUTS.
THE SECRETARY OF EDUCATION WASHINGTON, DC 20202 May 5, 2025 Dr. Alan Garber Office of the President Harvard University Massachusetts Hall Cambridge, MA 02138 Dr. Garber, The Federal Government has a sacred responsibility to be a wise and important steward of American taxpayer dollars. Harvard University, despite amassing a largely tax-free $53.2 billion dollar endowment (larger than the GDP of 100 countries), receives billions of dollars of taxpayer largess each year. Receiving such taxpayer funds is a privilege, not a right. Yet instead of using these funds to advance the education of its students, Harvard is engaging in a systemic pattern of violating federal law. Where do many of these "students" come from, who are they, how do they get into Harvard, or even into our country—and why is there so much HATE? These are questions that must be answered, among many more, but the biggest question of all is, why will Harvard not give straightforward answers to the American public? Harvard University has made a mockery of this country's higher education system. It has invited foreign students, who engage in violent behavior and show contempt for the United States of America, to its campus. In every way, Harvard has failed to abide by its legal obligations, its ethical and fiduciary duties, its transparency responsibilities, and any semblance of academic rigor. It had scrapped standardized testing requirements and a normalized grading system. This year Harvard was forced to adopt an embarrassing "remedial math" program for undergraduates. Why is it, we ask, that Harvard has to teach simple and basic mathematics, when it is supposedly so hard to get into this "acclaimed university"? Who is getting in under such a low standard when others, with fabulous grades and a great understanding of the highest levels of mathematics, are being rejected? Harvard has even been embroiled in humiliating plagiarism scandals, exposed clearly and plainly in the media, with respect to your then… running the institution in a totally chaotic way. Harvard alumnus and highly successful hedge fund manager Bill Ackman noted that, under her leadership, Harvard has become "a political advocacy organization for one party." Ackman has called for the resignation of Pritzker, concluding that the "[t)he mismanagement here is Penny Pritzker" and noting that any serious corporation would have removed her after a litany of recent failings and the fact that, incredibly, "Harvard is not in a good financial position." According to Ackman, one of the world's foremost finance experts, Harvard's so-called S53 billion endowment is "massively overstated as far as what it's really worth," and Harvard has irresponsibly taken out $8 billion in debt. If this is true, it is concerning evidence of Harvard's disastrous mismanagement, indicating an urgent need for massive reform-not continued taxpayer investment. If Harvard prefers not to change, then Harvard should have no problem using its overflowing endowment to fund its bloated bureaucracy. At its best, a university should fulfill the highest ideals of our Nation, and enlighten the thousands of hopeful students who walk through its magnificent gates. But Harvard has betrayed this ideal. Perhaps most alarmingly, Harvard has failed to abide by the United States Supreme Court's ruling demanding that it end its racial preferencing, and continues to engage in ugly racism in its undergraduate and graduate schools, and even within the Harvard Law Review itself. Our universities should be bastions of merit that reward and celebrate excellence and achievement. They should not be incubators of discrimination that encourage resentment and instill grievance and racism into our wonderful young Americans. The above concerns are only a fraction of the long list of Harvard's consistent violations of its own legal duties. Given these and other concerning allegations, this letter is to inform you that Harvard should no longer seek GRANTS from the fede… Federal Agencies. The Administration's priorities have not changed and today's letter marks the end of new grants for the University. These requests will advance the best interests of Harvard University, so it can reclaim its status as a respected educational institution for the future leaders of America. Thank you for your attention to this matter! Sincerely, Linda E. McMahon Secretary of Education
May 6, 2025 at 4:01 AM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
carolynbertozzi.bskyverified.social
The current administration’s narrative that Harvard (and all universities) feel “entitled” to federal dollars misleads the public. Nor are these funds a “privilege” 1/n
krishnanyamuna.bsky.social Yamuna Krishnan @krishnanyamuna.bsky.social · May 6
Harvard may have a lot of issues, but none of the accusations in this acid-tripping letter are it. Don't know whether to laugh or cry as I watch monkeys tear up pearl strings.
ericcolumbus.bsky.social Eric Columbus @ericcolumbus.bsky.social · May 6
🚨🚨 Deranged letter from Education Secretary Linda McMahon to Harvard’s president, cutting off federal funding for any new grants.

Worth reading in full. It is NUTS.
May 6, 2025 at 1:31 AM
seanmwu.bsky.social
Great to see @harvard.edu take a stand on the unlawful infringement of the current government on academic freedom and freedom of speech. I’m proud to have trained as a fellow at Harvard Med/MGH & as an HMS Assist Prof previously. 👍👍👏👏💪💪
Now is the time for all other universities to do the same.
April 14, 2025 at 10:46 PM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
malindalo.bsky.social
Harvard redid its whole homepage to push back against the administration’s demands. I mean, this is just a website but I think it’s kind of a great PR move: www.harvard.edu
Harvard University
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.
www.harvard.edu
April 14, 2025 at 7:10 PM
seanmwu.bsky.social
Nice!! They need to add one in Boston also.
April 3, 2025 at 7:02 AM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
erinmichos.bsky.social
#SOUL trial presented at #ACC25. Oral #semaglutide reduced 3-pt major adverse cardiovascular events by 14% in patients with T2D, even with high background SGLTi use. In exploratory analysis, oral sema also reduced major limb events. #CardioSky @accintouch.bsky.social
March 29, 2025 at 6:46 PM
seanmwu.bsky.social
Did you know that the hippopotamus has a heart rate of 34 bpm & a QRS axis pointing 2 its neck? See-Cardiac conduction system & the electrocardiogram of the common hippopotamus (Hippopotamus amphibius) pubmed.ncbi.nlm.nih.gov/40153832/ Super interesting how different species adapt 2 size & function.
March 29, 2025 at 7:45 PM
seanmwu.bsky.social
Thanks so much Peter, Han @hankim and the trainees Aidan, Termeh for the great hospitality. It was wonderful to see you all at UOHI.
drpeterpliu.bsky.social drpeterpliu.bsky.social @drpeterpliu.bsky.social · Mar 24
The #Ottawa Heart Institute trainees were privileged to host the famed Prof Sean Wu @seanmwu.bsky.social from @stanford.edu at @brownsocialhouse.com. #mentorship discussions ranged from academic careers to #entrepreneurship to Spark programs and future of science. Exciting lecture tomorrow noon.
March 24, 2025 at 8:22 PM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
harrymok.bsky.social
Two of the most decorated U.S. military units get scrubbed from Army website.
JACL condemns Trump erasure of 442nd and 100th Infantry Battalion – AsAmNews
The accomplishments of the Japanese American 442nd Regimental Combat unit and the 100th Infantry Battalion have been removed from the Army's website.
asamnews.com
March 15, 2025 at 7:33 PM
Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA
docsirianni.bsky.social
This is horrible to post, but I may as well post it. We are essentially shutting down research operations in my group, which is focused on treatments for pediatric brain cancer. I’m a well funded investigator, and there’s no choice. Science can’t function without the stability of NIH
March 15, 2025 at 5:32 PM