Leah Rosin
@scienceleah.bsky.social
Scientist. Mom.
Meiosis, mitosis, and gene regulation.
Moth and fly model systems 🦋🪰
Microscopy and genomics 🔬🧬
Views are my own.
Meiosis, mitosis, and gene regulation.
Moth and fly model systems 🦋🪰
Microscopy and genomics 🔬🧬
Views are my own.
Pinned
Leah Rosin
@scienceleah.bsky.social
· Aug 4
Programmed meiotic errors facilitate dichotomous sperm production in the silkworm, Bombyx mori
The goal of meiosis is typically to produce haploid gametes (eggs or sperm). Failure to do so is catastrophic for fertility and offspring health. However, Lepidopteran (moths and butterflies) males pr...
www.biorxiv.org
So excited to share this preprint from the Rosin lab in collaboration with the Hawley lab and @eelcotromer.bsky.social on moth spermatogenesis! We investigate the meiotic errors that occur during the formation of apyrene sperm (that have no DNA) in silkworms!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Leah Rosin
I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions.
Descriptions and links in the following two posts.
Descriptions and links in the following two posts.
August 28, 2025 at 8:47 PM
I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions.
Descriptions and links in the following two posts.
Descriptions and links in the following two posts.
So excited to share this preprint from the Rosin lab in collaboration with the Hawley lab and @eelcotromer.bsky.social on moth spermatogenesis! We investigate the meiotic errors that occur during the formation of apyrene sperm (that have no DNA) in silkworms!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Programmed meiotic errors facilitate dichotomous sperm production in the silkworm, Bombyx mori
The goal of meiosis is typically to produce haploid gametes (eggs or sperm). Failure to do so is catastrophic for fertility and offspring health. However, Lepidopteran (moths and butterflies) males pr...
www.biorxiv.org
August 4, 2025 at 10:38 AM
So excited to share this preprint from the Rosin lab in collaboration with the Hawley lab and @eelcotromer.bsky.social on moth spermatogenesis! We investigate the meiotic errors that occur during the formation of apyrene sperm (that have no DNA) in silkworms!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Leah Rosin
So important! Please contact your Republican senators, especially Sen. Susan Collins (R-ME), Sen. Shelley Moore Capito (R-WV), Sen. Bill Cassidy (R-LA), Sen. Katie Britt (R-AL), and Sen. Dave McCormick (R-PA). 🙏 amplify!
As Robert Kuttner writes, the NIH will need support from Republican Senators to avoid draconian cuts to its FY2026 budget.
prospect.org/politics/202...
prospect.org/politics/202...
Will the Senate Save NIH?
Rescuing biomedical research is every bit as important as saving Medicaid.
prospect.org
June 25, 2025 at 1:01 AM
So important! Please contact your Republican senators, especially Sen. Susan Collins (R-ME), Sen. Shelley Moore Capito (R-WV), Sen. Bill Cassidy (R-LA), Sen. Katie Britt (R-AL), and Sen. Dave McCormick (R-PA). 🙏 amplify!
Reposted by Leah Rosin
🚨Postdoc opportunity🚨: LepEU postdoc: comparative population genomics of European scale adaptation in butterflies
2 year, full-time PD in my group, Stockholm Univ.
Applications assed on rolling basis, deadline: 23 August 2025. Planned start 1 Oct.
Details:
christopherwheatlab.wordpress.com
2 year, full-time PD in my group, Stockholm Univ.
Applications assed on rolling basis, deadline: 23 August 2025. Planned start 1 Oct.
Details:
christopherwheatlab.wordpress.com
June 22, 2025 at 6:20 PM
🚨Postdoc opportunity🚨: LepEU postdoc: comparative population genomics of European scale adaptation in butterflies
2 year, full-time PD in my group, Stockholm Univ.
Applications assed on rolling basis, deadline: 23 August 2025. Planned start 1 Oct.
Details:
christopherwheatlab.wordpress.com
2 year, full-time PD in my group, Stockholm Univ.
Applications assed on rolling basis, deadline: 23 August 2025. Planned start 1 Oct.
Details:
christopherwheatlab.wordpress.com
Reposted by Leah Rosin
🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
May 21, 2025 at 5:39 PM
🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
Reposted by Leah Rosin
We're hiring an entomology collections manager @nhm.org ! I have nothing to do with the search, but happy to answer questions about the museum & LA!
🧪🦋🐝🐞🐜🦗🪰🪲🪳🕷️
workforcenow.adp.com/mascsr/defau...
🧪🦋🐝🐞🐜🦗🪰🪲🪳🕷️
workforcenow.adp.com/mascsr/defau...
Recruitment
workforcenow.adp.com
May 23, 2025 at 1:17 AM
We're hiring an entomology collections manager @nhm.org ! I have nothing to do with the search, but happy to answer questions about the museum & LA!
🧪🦋🐝🐞🐜🦗🪰🪲🪳🕷️
workforcenow.adp.com/mascsr/defau...
🧪🦋🐝🐞🐜🦗🪰🪲🪳🕷️
workforcenow.adp.com/mascsr/defau...
Reposted by Leah Rosin
@jeffsekelsky.bsky.social Corbin Jones, & I give huge thanks to Frank McNally, Christoph Haag, Andy Kern, Bengt Hansson, @takashiakeralab.bsky.social & @scienceleah.bsky.social for being guests in our #Meiosis, Recombination, & Evolution of Sex class at UNC. A pic from our final session w/ students
April 25, 2025 at 7:45 PM
@jeffsekelsky.bsky.social Corbin Jones, & I give huge thanks to Frank McNally, Christoph Haag, Andy Kern, Bengt Hansson, @takashiakeralab.bsky.social & @scienceleah.bsky.social for being guests in our #Meiosis, Recombination, & Evolution of Sex class at UNC. A pic from our final session w/ students
Reposted by Leah Rosin
Happy to share a new preprint from my lab! We characterize the on/off kinetics, light dosage-dependence, and more for a suite of optogenetic signaling activators in zebrafish embryos 💡 www.biorxiv.org/content/10.1...
An optogenetic toolkit for robust activation of FGF, BMP, and Nodal signaling in zebrafish
Cell signaling regulates a wide range of biological processes including development, homeostasis, and disease. Accessible technologies to precisely manipulate signaling have important applications in ...
www.biorxiv.org
April 21, 2025 at 1:47 PM
Happy to share a new preprint from my lab! We characterize the on/off kinetics, light dosage-dependence, and more for a suite of optogenetic signaling activators in zebrafish embryos 💡 www.biorxiv.org/content/10.1...
Reposted by Leah Rosin
I’m excited to share a new preprint from some of my work in the lab of @toddmacfarlan.bsky.social ! 😄
We dived into young KZFP gene clusters in different mouse strains and species to uncover mechanisms that facilitated their evolution and diversification in mice
We dived into young KZFP gene clusters in different mouse strains and species to uncover mechanisms that facilitated their evolution and diversification in mice
Young KRAB-zinc finger gene clusters are highly dynamic incubators of ERV-driven genetic heterogeneity in mice https://www.biorxiv.org/content/10.1101/2025.02.26.640358v1
March 3, 2025 at 6:41 PM
I’m excited to share a new preprint from some of my work in the lab of @toddmacfarlan.bsky.social ! 😄
We dived into young KZFP gene clusters in different mouse strains and species to uncover mechanisms that facilitated their evolution and diversification in mice
We dived into young KZFP gene clusters in different mouse strains and species to uncover mechanisms that facilitated their evolution and diversification in mice
Reposted by Leah Rosin
Our (@jeffsekelsky.bsky.social Corbin Jones, & me) #Meiosis, Recombination & Evolution of Sex class @uncchapelhill.bsky.social loved talking w/ @scienceleah.bsky.social about her lab's @plos.org Genetics paper on a unique chromosome segregation mechanism in holocentric moths. doi.org/10.1371/jour...
April 11, 2025 at 7:31 PM
Our (@jeffsekelsky.bsky.social Corbin Jones, & me) #Meiosis, Recombination & Evolution of Sex class @uncchapelhill.bsky.social loved talking w/ @scienceleah.bsky.social about her lab's @plos.org Genetics paper on a unique chromosome segregation mechanism in holocentric moths. doi.org/10.1371/jour...
Reposted by Leah Rosin
Did you know…
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
April 9, 2025 at 2:32 PM
Did you know…
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
Reposted by Leah Rosin
New preprint drop! Check out work from @jimmy-ly.bsky.social et al for how protein isoforms generated by alternate translation initiation create dual localization, contribute to mitochondrial function, and are mutated in disease. "Blue-tutorial" thread below.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
March 28, 2025 at 10:41 AM
New preprint drop! Check out work from @jimmy-ly.bsky.social et al for how protein isoforms generated by alternate translation initiation create dual localization, contribute to mitochondrial function, and are mutated in disease. "Blue-tutorial" thread below.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Leah Rosin
🚨 New Paper Alert! 🚨
🐜 How did ants evolve their highly specialized queens and workers?
With @adriatica.bsky.social, we reveal a key evolutionary innovation: adult control over larval feeding unlocked extreme caste dimorphism and complex societies. 🧵👇
🔗 Read in @pnas.org: doi.org/10.1073/pnas...
🐜 How did ants evolve their highly specialized queens and workers?
With @adriatica.bsky.social, we reveal a key evolutionary innovation: adult control over larval feeding unlocked extreme caste dimorphism and complex societies. 🧵👇
🔗 Read in @pnas.org: doi.org/10.1073/pnas...
February 26, 2025 at 12:37 PM
🚨 New Paper Alert! 🚨
🐜 How did ants evolve their highly specialized queens and workers?
With @adriatica.bsky.social, we reveal a key evolutionary innovation: adult control over larval feeding unlocked extreme caste dimorphism and complex societies. 🧵👇
🔗 Read in @pnas.org: doi.org/10.1073/pnas...
🐜 How did ants evolve their highly specialized queens and workers?
With @adriatica.bsky.social, we reveal a key evolutionary innovation: adult control over larval feeding unlocked extreme caste dimorphism and complex societies. 🧵👇
🔗 Read in @pnas.org: doi.org/10.1073/pnas...
First mouse paper out from Elissa Lei’s lab! Congrats Dahong and all authors 🐭🐁🧬👀
“CTCF regulates global chromatin accessibility and transcription during rod photoreceptor development”
www.pnas.org/doi/10.1073/...
“CTCF regulates global chromatin accessibility and transcription during rod photoreceptor development”
www.pnas.org/doi/10.1073/...
www.pnas.org
February 24, 2025 at 10:50 PM
First mouse paper out from Elissa Lei’s lab! Congrats Dahong and all authors 🐭🐁🧬👀
“CTCF regulates global chromatin accessibility and transcription during rod photoreceptor development”
www.pnas.org/doi/10.1073/...
“CTCF regulates global chromatin accessibility and transcription during rod photoreceptor development”
www.pnas.org/doi/10.1073/...
Reposted by Leah Rosin
Check out our super cool paper on aneuploidy in cells lacking Bub3. Congratulations to fantastic student Pallavi Gadgil and alum Olivia Ballew. journals.plos.org/plosgenetics...
Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3
Author summary Accurate chromosome segregation is crucial for the proper development of all living organisms. Errors in chromosome segregation can lead to aneuploidy, characterized by an abnormal numb...
journals.plos.org
February 21, 2025 at 6:41 PM
Check out our super cool paper on aneuploidy in cells lacking Bub3. Congratulations to fantastic student Pallavi Gadgil and alum Olivia Ballew. journals.plos.org/plosgenetics...
Reposted by Leah Rosin
I am thrilled to share our new review on holocentric chromosomes. It was a lot of fun to write it together with Ines Drinnenberg!
Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...
Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...
February 21, 2025 at 9:17 AM
I am thrilled to share our new review on holocentric chromosomes. It was a lot of fun to write it together with Ines Drinnenberg!
Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...
Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...
Reposted by Leah Rosin
Do you love meiosis? Have a cool story to share? Join us for the XVth British Meiosis Meeting 26-27 of March in Liverpool! docs.google.com/forms/d/e/1F... You only have till Sunday to submit an abstract for a talk! ECRs are prioritised for speaking slots so the odds are in your favour 😁 #meiosis4eva
February 19, 2025 at 11:30 AM
Do you love meiosis? Have a cool story to share? Join us for the XVth British Meiosis Meeting 26-27 of March in Liverpool! docs.google.com/forms/d/e/1F... You only have till Sunday to submit an abstract for a talk! ECRs are prioritised for speaking slots so the odds are in your favour 😁 #meiosis4eva
Reposted by Leah Rosin
Almost 200 people signed up already - add your name soon before we have to stop registration for this once in a life time conference! docs.google.com/forms/d/1dm8...
February 9, 2025 at 3:40 PM
Almost 200 people signed up already - add your name soon before we have to stop registration for this once in a life time conference! docs.google.com/forms/d/1dm8...
Reposted by Leah Rosin
I just heard the news that R Scott Hawley, meiosis enthusiast and founding Dean of the Grad School of the Stowers Institute for Medical Research, passed away today. Such a loss for the science and education community. I will miss our zooms and his deep, deep wisdom
January 31, 2025 at 6:50 PM
I just heard the news that R Scott Hawley, meiosis enthusiast and founding Dean of the Grad School of the Stowers Institute for Medical Research, passed away today. Such a loss for the science and education community. I will miss our zooms and his deep, deep wisdom
Reposted by Leah Rosin
Feeling very lost today with the news of the passing of my undergrad advisor Scott Hawley. He had a huge impact on the field and on me personally. He was the first person to see me as a scientist and gave me the confidence to apply to grad school. I am so grateful to be a part of his legacy.
January 31, 2025 at 4:37 PM
Feeling very lost today with the news of the passing of my undergrad advisor Scott Hawley. He had a huge impact on the field and on me personally. He was the first person to see me as a scientist and gave me the confidence to apply to grad school. I am so grateful to be a part of his legacy.
Reposted by Leah Rosin
Sadly, our colleague and friend Scott Hawley passed away this morning. He was an irreplaceable presence and force for good in the meiosis an Drosophila communities and will be sorely missed.
January 31, 2025 at 3:45 PM
Sadly, our colleague and friend Scott Hawley passed away this morning. He was an irreplaceable presence and force for good in the meiosis an Drosophila communities and will be sorely missed.
Scientists of Bluesky - qPCR machine recs?
December 14, 2024 at 9:23 PM
Scientists of Bluesky - qPCR machine recs?
Reposted by Leah Rosin
I was deeply disappointed by the lack of nature/science/climate/enviro on many major end-of-year book lists—so I decided to make my own!
Introducing: ✨🎁📚 The 2024 Holiday Gift Guide to Nature & Science Books ✨🎁📚
Please share: Let's make this go viral in time for Black Friday / holiday shopping!
Introducing: ✨🎁📚 The 2024 Holiday Gift Guide to Nature & Science Books ✨🎁📚
Please share: Let's make this go viral in time for Black Friday / holiday shopping!
November 27, 2024 at 7:08 PM
I was deeply disappointed by the lack of nature/science/climate/enviro on many major end-of-year book lists—so I decided to make my own!
Introducing: ✨🎁📚 The 2024 Holiday Gift Guide to Nature & Science Books ✨🎁📚
Please share: Let's make this go viral in time for Black Friday / holiday shopping!
Introducing: ✨🎁📚 The 2024 Holiday Gift Guide to Nature & Science Books ✨🎁📚
Please share: Let's make this go viral in time for Black Friday / holiday shopping!
Reposted by Leah Rosin
Our #SpotlightZebrafish this week is on Dr. Abhinav Sur, a #postdoc w/ Dr. Jeff Farrell @ NICHD. His research uses single-cell transcriptomes to identify & map distinct populations across 62 stages of zebrafish embryogenesis & early larval development. (1/3)
September 25, 2023 at 3:05 PM
Our #SpotlightZebrafish this week is on Dr. Abhinav Sur, a #postdoc w/ Dr. Jeff Farrell @ NICHD. His research uses single-cell transcriptomes to identify & map distinct populations across 62 stages of zebrafish embryogenesis & early larval development. (1/3)