SchmitzStreitsLAB
@schmitzstreitslab.bsky.social
We are interested in #archaea,#regulation,#ncRNA,#smallproteins & novel biomolecules from nature, CAU Kiel
https://www.mikrobio.uni-kiel.de/de/ag-schmitz-streit
Views are our own
https://www.mikrobio.uni-kiel.de/de/ag-schmitz-streit
Views are our own
Pinned
Small ORF16 modulates the Mtr complex activity in Methanosarcina mazei Gö1 depending on the molecular hydrogen availability
Small open reading frame (small ORF)-encoded proteins, with less than 100 amino acids in length, have attracted increasing attention over the past decade after being largely overlooked due to limitati...
www.biorxiv.org
Check out our latest preprint on small proteins with big impact: MtrR fine-tunes energy metabolism in M.mazei by modulating the Mtr complex in response to H₂. Great work of Tim Habenicht + @SPP2002 collegues + @schullerjm.bsky.social - congrats TIM, 2. step to PhD!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by SchmitzStreitsLAB
An Asgard archaeon containing internal membrane compartments!! 😯
This will reshape our understanding of how the eukaryotic endomembrane system originated.
Congrats to @buzzbaum.bsky.social, @tbharat-lab.bsky.social and all ppl involved!
www.biorxiv.org/content/10.1...
This will reshape our understanding of how the eukaryotic endomembrane system originated.
Congrats to @buzzbaum.bsky.social, @tbharat-lab.bsky.social and all ppl involved!
www.biorxiv.org/content/10.1...
An Asgard archaeon with internal membrane compartments
The emergence of eukaryotes from a merger between an archaeon and a bacterial cell ~two billion years ago involved a profound change in cellular organisation. While the order in which different featur...
www.biorxiv.org
November 8, 2025 at 5:15 PM
An Asgard archaeon containing internal membrane compartments!! 😯
This will reshape our understanding of how the eukaryotic endomembrane system originated.
Congrats to @buzzbaum.bsky.social, @tbharat-lab.bsky.social and all ppl involved!
www.biorxiv.org/content/10.1...
This will reshape our understanding of how the eukaryotic endomembrane system originated.
Congrats to @buzzbaum.bsky.social, @tbharat-lab.bsky.social and all ppl involved!
www.biorxiv.org/content/10.1...
Reposted by SchmitzStreitsLAB
New article online: Modulation of archaeal hypernucleosome structure and stability by Mg2+
In this work, we dissect the effects of Mg2+ on hypernucleosomes formed by the canonical histones from M. fervidus (HMfA and HMfB) and T. kodakarensis (HTkA and HTkB).
www.sciencedirect.com/science/arti...
In this work, we dissect the effects of Mg2+ on hypernucleosomes formed by the canonical histones from M. fervidus (HMfA and HMfB) and T. kodakarensis (HTkA and HTkB).
www.sciencedirect.com/science/arti...
Modulation of archaeal hypernucleosome structure and stability by Mg2+
DNA-wrapping histone proteins play a central role in chromatin organization, gene expression and regulation in most eukaryotes and archaea. While the …
www.sciencedirect.com
November 6, 2025 at 7:53 AM
New article online: Modulation of archaeal hypernucleosome structure and stability by Mg2+
In this work, we dissect the effects of Mg2+ on hypernucleosomes formed by the canonical histones from M. fervidus (HMfA and HMfB) and T. kodakarensis (HTkA and HTkB).
www.sciencedirect.com/science/arti...
In this work, we dissect the effects of Mg2+ on hypernucleosomes formed by the canonical histones from M. fervidus (HMfA and HMfB) and T. kodakarensis (HTkA and HTkB).
www.sciencedirect.com/science/arti...
Reposted by SchmitzStreitsLAB
Preprint: Bacteria sense virus-induced genome degradation via methylated mononucleotides
tinyurl.com/ch3damp
We show how molecular byproducts released during virus-induced cell exploitation are used as signals to trigger host immunity
Revealed by the amazing Ilya Osterman. See his thread below👇
tinyurl.com/ch3damp
We show how molecular byproducts released during virus-induced cell exploitation are used as signals to trigger host immunity
Revealed by the amazing Ilya Osterman. See his thread below👇
November 6, 2025 at 10:39 AM
Preprint: Bacteria sense virus-induced genome degradation via methylated mononucleotides
tinyurl.com/ch3damp
We show how molecular byproducts released during virus-induced cell exploitation are used as signals to trigger host immunity
Revealed by the amazing Ilya Osterman. See his thread below👇
tinyurl.com/ch3damp
We show how molecular byproducts released during virus-induced cell exploitation are used as signals to trigger host immunity
Revealed by the amazing Ilya Osterman. See his thread below👇
Reposted by SchmitzStreitsLAB
True!
Scientists feel that the pressure to publish is rising, but that the time and resources they have to do the necessary research are falling, according to a survey of 3,200 researchers
go.nature.com/4hNDvuN
go.nature.com/4hNDvuN
Pressure to publish is rising as research time shrinks, finds survey of scientists
Researchers feel that pressures to publish are increasing, but the time and resources available to do research are decreasing, according to a survey by Elsevier.
go.nature.com
November 7, 2025 at 2:19 PM
True!
Reposted by SchmitzStreitsLAB
Hey folks, as news of Watson's demise spreads, please don't set aside his weighty legacy of misogyny and racism. He was truly among the worst of us. www.vox.com/2019/1/15/18...
DNA scientist James Watson has a remarkably long history of sexist, racist public comments
“People say it would be terrible if we made all girls pretty,” he said in 2003. “I think it would be great.”
www.vox.com
November 7, 2025 at 7:45 PM
Hey folks, as news of Watson's demise spreads, please don't set aside his weighty legacy of misogyny and racism. He was truly among the worst of us. www.vox.com/2019/1/15/18...
Reposted by SchmitzStreitsLAB
Thinking only of Rosalind Franklin today, and what was stolen from her (and so many other female scientists alongside her).
Rosalind Franklin and the damage of gender harassment
Spurred by a recent report on sexual harassment in academia, our columnist revisits a historical case and reflects on what has changed—and what hasn’t
www.science.org
November 7, 2025 at 7:58 PM
Thinking only of Rosalind Franklin today, and what was stolen from her (and so many other female scientists alongside her).
Reposted by SchmitzStreitsLAB
Soon available in my group: 1 PhD position to investigate prokaryotic histones. See our recent work that highlights the existence and diversity of prokaryotic histones (e.g. Schwab et al., TIBS, 2025; Schwab et al., Nat Comm, 2024; Hu et al., Nucl Acids Res, 2024). Please DM for informal enquiries.
November 5, 2025 at 12:57 PM
Soon available in my group: 1 PhD position to investigate prokaryotic histones. See our recent work that highlights the existence and diversity of prokaryotic histones (e.g. Schwab et al., TIBS, 2025; Schwab et al., Nat Comm, 2024; Hu et al., Nucl Acids Res, 2024). Please DM for informal enquiries.
Reposted by SchmitzStreitsLAB
Are you interested in studying RNA phages? We are looking for a PhD student and a postdoc to join the lab!
For more information and how to apply, see below 👇
Please RT!
For more information and how to apply, see below 👇
Please RT!
📢 The #HIRI is looking for a #postdoc & a #PhD student to join the research group of @jenshoer.bsky.social. His lab focuses on understanding the molecular mechanisms of #phages with #RNA genomes during infection, host takeover & anti-phage defense. 🧫🦠 More info: www.helmholtz-hiri.de/en/jobs-tale...
Working at HIRI
At the HIRI, we do not just value excellent research. Short distances, an open door policy, and a good working atmosphere—this is what distinguishes us from others. Have a look at our current job…
www.helmholtz-hiri.de
October 17, 2025 at 12:52 PM
Are you interested in studying RNA phages? We are looking for a PhD student and a postdoc to join the lab!
For more information and how to apply, see below 👇
Please RT!
For more information and how to apply, see below 👇
Please RT!
Reposted by SchmitzStreitsLAB
📢 Postdoc position: Cell Biology of Cyanobacteria
in my group, as part of the Excellence Cluster "Microbes for Climate" (M4C) in Marburg, Germany.
More information at shorturl.at/wNnDT (see Project 2)
🔗Apply at shorturl.at/VsEDl
📅Deadline: Nov 16, 2025
Please repost. #Postdoc
in my group, as part of the Excellence Cluster "Microbes for Climate" (M4C) in Marburg, Germany.
More information at shorturl.at/wNnDT (see Project 2)
🔗Apply at shorturl.at/VsEDl
📅Deadline: Nov 16, 2025
Please repost. #Postdoc
November 2, 2025 at 7:13 PM
📢 Postdoc position: Cell Biology of Cyanobacteria
in my group, as part of the Excellence Cluster "Microbes for Climate" (M4C) in Marburg, Germany.
More information at shorturl.at/wNnDT (see Project 2)
🔗Apply at shorturl.at/VsEDl
📅Deadline: Nov 16, 2025
Please repost. #Postdoc
in my group, as part of the Excellence Cluster "Microbes for Climate" (M4C) in Marburg, Germany.
More information at shorturl.at/wNnDT (see Project 2)
🔗Apply at shorturl.at/VsEDl
📅Deadline: Nov 16, 2025
Please repost. #Postdoc
Reposted by SchmitzStreitsLAB
🌊 Wie geht nachhaltiger #Küstenschutz? Statt nur auf höhere Deiche zu setzen, sucht Dr. Claudia Wolff @uni-kiel.de mit Gemeinden, Behörden und NGOs nach neuen Wegen.
Wir drücken die Daumen und unterstützen mit einem "Change! Fellowship"!
#Forschung #Nachhaltigkeit #Klimawandel #Ostsee
Wir drücken die Daumen und unterstützen mit einem "Change! Fellowship"!
#Forschung #Nachhaltigkeit #Klimawandel #Ostsee
Küsten unter Druck – Neue Strategien für den Küstenschutz | VolkswagenStiftung
Sturmfluten, steigende Pegel, gefährdete Küsten: Dr. Claudia Wolff von der Universität Kiel sucht im Rahmen ihres "Change!-Fellowships" gemeinsam mit lokalen Akteur:innen nach neuen Wegen für nachhalt...
www.volkswagenstiftung.de
November 3, 2025 at 8:02 AM
🌊 Wie geht nachhaltiger #Küstenschutz? Statt nur auf höhere Deiche zu setzen, sucht Dr. Claudia Wolff @uni-kiel.de mit Gemeinden, Behörden und NGOs nach neuen Wegen.
Wir drücken die Daumen und unterstützen mit einem "Change! Fellowship"!
#Forschung #Nachhaltigkeit #Klimawandel #Ostsee
Wir drücken die Daumen und unterstützen mit einem "Change! Fellowship"!
#Forschung #Nachhaltigkeit #Klimawandel #Ostsee
Reposted by SchmitzStreitsLAB
How to become a "hot RNA" 🌡️? The answers were kindly provided by hyperthermophilic archaea: rRNA modifications are key! Check out this new publication presenting pan-modification profiling of the epitranscriptome. www.cell.com/cell/fulltex.... (1/3)
Pan-modification profiling facilitates a cross-evolutionary dissection of the thermoregulated ribosomal epitranscriptome
Pan-Mod-seq enables systematic, multi-modification mapping of rRNA across life. Applying
it to diverse organisms reveals that hyperthermophiles dynamically install stabilizing
modifications to support...
www.cell.com
October 27, 2025 at 1:19 PM
How to become a "hot RNA" 🌡️? The answers were kindly provided by hyperthermophilic archaea: rRNA modifications are key! Check out this new publication presenting pan-modification profiling of the epitranscriptome. www.cell.com/cell/fulltex.... (1/3)
Reposted by SchmitzStreitsLAB
Do you want to do a Masters in Evolutionary Biology? The call for applying to the MEME program is now open! MEME is a fantastic 2-year MSc between four European Universities on all areas of Evolutionary Biology. Apply and study in Sweden/France/the Netherlands/Germany/USA/Switzerland! www.evobio.eu
October 24, 2025 at 9:04 AM
Do you want to do a Masters in Evolutionary Biology? The call for applying to the MEME program is now open! MEME is a fantastic 2-year MSc between four European Universities on all areas of Evolutionary Biology. Apply and study in Sweden/France/the Netherlands/Germany/USA/Switzerland! www.evobio.eu
Reposted by SchmitzStreitsLAB
In 4 Wochen ist es soweit: Am 21. November findet die Night of the Profs 2025 an der @uni-kiel.de statt. 🌕
Auch die Science Show ist wieder vertreten: Um 20:00 und um 21:00 Uhr, jeweils im Frederik-Paulsen-Hörsaal im Audimax, geben unsere Referent*innen kurze Einblicke in ihre Forschungen. 💡
Auch die Science Show ist wieder vertreten: Um 20:00 und um 21:00 Uhr, jeweils im Frederik-Paulsen-Hörsaal im Audimax, geben unsere Referent*innen kurze Einblicke in ihre Forschungen. 💡
October 24, 2025 at 12:22 PM
In 4 Wochen ist es soweit: Am 21. November findet die Night of the Profs 2025 an der @uni-kiel.de statt. 🌕
Auch die Science Show ist wieder vertreten: Um 20:00 und um 21:00 Uhr, jeweils im Frederik-Paulsen-Hörsaal im Audimax, geben unsere Referent*innen kurze Einblicke in ihre Forschungen. 💡
Auch die Science Show ist wieder vertreten: Um 20:00 und um 21:00 Uhr, jeweils im Frederik-Paulsen-Hörsaal im Audimax, geben unsere Referent*innen kurze Einblicke in ihre Forschungen. 💡
Reposted by SchmitzStreitsLAB
Our @narjournal.bsky.social manuscript is out! It explores the growth of the GTDB (gtdb.ecogenomic.org) since its inception, as well as updates to the website, methodology, policies, and major taxonomic and nomenclatural changes over the past three years.
academic.oup.com/nar/advance-...
academic.oup.com/nar/advance-...
GTDB release 10: a complete and systematic taxonomy for 715 230 bacterial and 17 245 archaeal genomes
Abstract. The Genome Taxonomy Database (GTDB; https://gtdb.ecogenomic.org) provides a phylogenetically consistent and rank normalized genome-based taxonomy
academic.oup.com
October 22, 2025 at 2:20 PM
Our @narjournal.bsky.social manuscript is out! It explores the growth of the GTDB (gtdb.ecogenomic.org) since its inception, as well as updates to the website, methodology, policies, and major taxonomic and nomenclatural changes over the past three years.
academic.oup.com/nar/advance-...
academic.oup.com/nar/advance-...
Reposted by SchmitzStreitsLAB
Check out our paper on intricate nested interactions between viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts. Excellent collaboration with @deemteam.bsky.social, @anagtz.bsky.social and Michail Yakimov
Free access link: rdcu.be/eLtCH
🧵 by @yifanzhou.bsky.social 👇
Free access link: rdcu.be/eLtCH
🧵 by @yifanzhou.bsky.social 👇
Our work on viruses and virus satellites of haloarchaea and their DPANN symbionts is out today in Nature Microbiology!
@mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social
www.nature.com/articles/s41...
@mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social
www.nature.com/articles/s41...
Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions - Nature Microbiology
An exploration of the viromes of haloarchaea and their ultra-small DPANN symbionts reveals plasmid-derived satellites of viruses from both archaeal groups, highlighting the complexity of nested symbio...
www.nature.com
October 17, 2025 at 10:28 AM
Check out our paper on intricate nested interactions between viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts. Excellent collaboration with @deemteam.bsky.social, @anagtz.bsky.social and Michail Yakimov
Free access link: rdcu.be/eLtCH
🧵 by @yifanzhou.bsky.social 👇
Free access link: rdcu.be/eLtCH
🧵 by @yifanzhou.bsky.social 👇
Reposted by SchmitzStreitsLAB
Come be my chair at The University of Arizona! We have great bike riding, hiking, and of course, science! arizona.csod.com/ux/ats/caree...
Department Head, Department of Immunobiology
Strategic LeadershipDevelop and execute a bold
vision for the Department of Immunobiology that advances understanding of
how immune and micr...
arizona.csod.com
October 21, 2025 at 3:42 PM
Come be my chair at The University of Arizona! We have great bike riding, hiking, and of course, science! arizona.csod.com/ux/ats/caree...
Reposted by SchmitzStreitsLAB
Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions
Out now in Nature Microbiology, by Yifan Zhou, Mart Krupovic & colleagues.
@mkrupovic.bsky.social
@yifanzhou.bsky.social
@deemteam.bsky.social
www.nature.com/articles/s41...
Out now in Nature Microbiology, by Yifan Zhou, Mart Krupovic & colleagues.
@mkrupovic.bsky.social
@yifanzhou.bsky.social
@deemteam.bsky.social
www.nature.com/articles/s41...
Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions - Nature Microbiology
An exploration of the viromes of haloarchaea and their ultra-small DPANN symbionts reveals plasmid-derived satellites of viruses from both archaeal groups, highlighting the complexity of nested symbio...
www.nature.com
October 20, 2025 at 7:46 PM
Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions
Out now in Nature Microbiology, by Yifan Zhou, Mart Krupovic & colleagues.
@mkrupovic.bsky.social
@yifanzhou.bsky.social
@deemteam.bsky.social
www.nature.com/articles/s41...
Out now in Nature Microbiology, by Yifan Zhou, Mart Krupovic & colleagues.
@mkrupovic.bsky.social
@yifanzhou.bsky.social
@deemteam.bsky.social
www.nature.com/articles/s41...
Reposted by SchmitzStreitsLAB
Second up this WEDNESDAY at 10AM EST / 4 PM CET, we have an exciting talk from Dr. Yan Liao who will tell us about her research combing molecular genetics and advanced microscopy techniques to shed light on archaeal cell division!! Check your email or sign up for the link: forms.gle/6QvCjHH2H4pxro…
October 20, 2025 at 4:37 PM
Second up this WEDNESDAY at 10AM EST / 4 PM CET, we have an exciting talk from Dr. Yan Liao who will tell us about her research combing molecular genetics and advanced microscopy techniques to shed light on archaeal cell division!! Check your email or sign up for the link: forms.gle/6QvCjHH2H4pxro…
Reposted by SchmitzStreitsLAB
Archaea alert 🚨! This WEDNESDAY, Oct. 22nd at 10 AM EST / 4PM CET, we will kick off our fall seminar series with a talk from Dr. Nili Ostrov, co-founder of Cultivarium FRO, telling us about her organization’s work to accelerate genetics in non-model organisms including archaea!! Zoom link in email!
October 20, 2025 at 4:30 PM
Archaea alert 🚨! This WEDNESDAY, Oct. 22nd at 10 AM EST / 4PM CET, we will kick off our fall seminar series with a talk from Dr. Nili Ostrov, co-founder of Cultivarium FRO, telling us about her organization’s work to accelerate genetics in non-model organisms including archaea!! Zoom link in email!
Reposted by SchmitzStreitsLAB
We’re excited to announce the incredible speaker line-up for the Prokaryotic Cell Biology Conference! Join the leading researchers as they explore the latest advances in Nanoimaging, Cell Growth and Cellular Structures.
Join our speakers & register today! ➡️https://bit.ly/47rtkbw
#ProkaryoticCellBio
Join our speakers & register today! ➡️https://bit.ly/47rtkbw
#ProkaryoticCellBio
October 16, 2025 at 2:27 PM
We’re excited to announce the incredible speaker line-up for the Prokaryotic Cell Biology Conference! Join the leading researchers as they explore the latest advances in Nanoimaging, Cell Growth and Cellular Structures.
Join our speakers & register today! ➡️https://bit.ly/47rtkbw
#ProkaryoticCellBio
Join our speakers & register today! ➡️https://bit.ly/47rtkbw
#ProkaryoticCellBio
Reposted by SchmitzStreitsLAB
A new study from the Sternberg lab suggests that the telomerase function evolved from a defense system that protects bacteria against phages. Amazing!
1/10 Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from?
Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria.
www.biorxiv.org/content/10.1...
Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria.
www.biorxiv.org/content/10.1...
Antiviral reverse transcriptases reveal the evolutionary origin of telomerase
Defense-associated reverse transcriptases (DRTs) employ diverse and distinctive mechanisms of cDNA synthesis to protect bacteria against viral infection. However, much of DRT family diversity remains ...
www.biorxiv.org
October 17, 2025 at 5:30 PM
A new study from the Sternberg lab suggests that the telomerase function evolved from a defense system that protects bacteria against phages. Amazing!
Reposted by SchmitzStreitsLAB
We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3
October 17, 2025 at 2:56 PM
We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3
Congrats to the Flament and Schmitt team!!👍🥂 super exciting work!
Our work on ribosome hibernation in archaea is out!
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
October 14, 2025 at 6:40 AM
Congrats to the Flament and Schmitt team!!👍🥂 super exciting work!
Reposted by SchmitzStreitsLAB
Our work on ribosome hibernation in archaea is out!
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
October 13, 2025 at 4:26 PM
Our work on ribosome hibernation in archaea is out!
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
Reposted by SchmitzStreitsLAB
Happy Teacher’s Day! 🎉To celebrate, #FEMSMicrobiolLett has put together a new Thematic Issue highlighting how discoveries in the microbiology lab can be taught to inspire learning, build science literacy, and shape tomorrow’s solutions.
✨Read collection: buff.ly/3hPInyI
✨Read collection: buff.ly/3hPInyI
October 5, 2025 at 10:00 AM
Happy Teacher’s Day! 🎉To celebrate, #FEMSMicrobiolLett has put together a new Thematic Issue highlighting how discoveries in the microbiology lab can be taught to inspire learning, build science literacy, and shape tomorrow’s solutions.
✨Read collection: buff.ly/3hPInyI
✨Read collection: buff.ly/3hPInyI