Shawn Baker
@sandiegomics.bsky.social
Genomics consultant/advisor/investor
https://sandiegomics.com
https://sandiegomics.com
PacBio’s very expensive foray into short read sequencing is now officially over. 🙄
www.pacb.com/press_releas...
www.pacb.com/press_releas...
PacBio Completes Sale of Short-Read Sequencing Assets - PacBio
MENLO PARK, Calif., Feb. 02, 2026 (GLOBE NEWSWIRE) — PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced the completion of the sale of sel...
www.pacb.com
February 2, 2026 at 5:18 PM
PacBio’s very expensive foray into short read sequencing is now officially over. 🙄
www.pacb.com/press_releas...
www.pacb.com/press_releas...
Reposted by Shawn Baker
Reposted by Shawn Baker
Some close encounters with Jim Watson:
www.genengnews.com/topics/omics...
www.genengnews.com/topics/omics...
DNA and the Unraveling of James Watson
A personal reflection on the life, legacy, and controversies of DNA co-discoverer James Watson, following his death at age 97.
www.genengnews.com
November 10, 2025 at 5:13 PM
Some close encounters with Jim Watson:
www.genengnews.com/topics/omics...
www.genengnews.com/topics/omics...
Some consolidation in the single cell space - 10X Genomics (@10xgenomics.bsky.social) set to acquire Scale Biosciences
www.genengnews.com/topics/omics...
www.genengnews.com/topics/omics...
10x Genomics Scales Up, Agrees to Acquire Scale Biosciences
An exclusive interview with Serge Saxonov of 10x Genomics and Giovanna Prout of Scale Biosciences on what the acquisition means for single cell genomics.
www.genengnews.com
August 7, 2025 at 9:01 PM
Some consolidation in the single cell space - 10X Genomics (@10xgenomics.bsky.social) set to acquire Scale Biosciences
www.genengnews.com/topics/omics...
www.genengnews.com/topics/omics...
Reposted by Shawn Baker
📢 We are very proud to announce that over 50 of our #AVITI24 5D #multiomic systems have already been installed around the globe enabling scientists to unravel the most complex questions about our biology.
bit.ly/458UCky
bit.ly/458UCky
Element Biosciences Surpasses 50 AVITI24™ 5D Multiomic System Installations In Just Months
Element Biosciences today announced that installations of its flagship AVITI24 5D Multiomic system have surpassed 50 units globally.
bit.ly
July 29, 2025 at 2:34 PM
📢 We are very proud to announce that over 50 of our #AVITI24 5D #multiomic systems have already been installed around the globe enabling scientists to unravel the most complex questions about our biology.
bit.ly/458UCky
bit.ly/458UCky
Atlas, Twist's DNA data storage spin-off, is claiming that "pretty quickly" the majority of DNA sequencing (by "orders of magnitude") will be for reading data storage. I'm skeptical. Maybe we have different definitions of "pretty quickly".
#dnasynth #datastorage
www.genomeweb.com/business-new...
#dnasynth #datastorage
www.genomeweb.com/business-new...
Twist Spinoff Atlas Data Storage Designing Chip, Seeking Partner for Sequencing DNA-Based Archives
The California startup will have to convince companies across the economy to swap from rolls of magnetic tape to DNA as the vessel for their most important digital data.
www.genomeweb.com
July 3, 2025 at 7:16 PM
Atlas, Twist's DNA data storage spin-off, is claiming that "pretty quickly" the majority of DNA sequencing (by "orders of magnitude") will be for reading data storage. I'm skeptical. Maybe we have different definitions of "pretty quickly".
#dnasynth #datastorage
www.genomeweb.com/business-new...
#dnasynth #datastorage
www.genomeweb.com/business-new...
Reposted by Shawn Baker
Quick update on this - a good one!
Thanks to our fantastic colleagues at county HHSA, we're able to continue our wastewater surveillance work, including generating retroactive data from the last few months, as well as new data moving forward.
For how long, we'll see, but expect updates soon! 🌟❤️
Thanks to our fantastic colleagues at county HHSA, we're able to continue our wastewater surveillance work, including generating retroactive data from the last few months, as well as new data moving forward.
For how long, we'll see, but expect updates soon! 🌟❤️
Very thankful to @sandiegouniontribune.com for covering the termination of our wastewater surveillance in San Diego.
If we don't want to lose sight of infectious diseases in our community, we need new funding - please reach out: searchcovid.info
www.sandiegouniontribune.com/2025/04/07/d...
If we don't want to lose sight of infectious diseases in our community, we need new funding - please reach out: searchcovid.info
www.sandiegouniontribune.com/2025/04/07/d...
DOGE cuts shut down San Diego County’s wastewater testing system
Other alternatives are available, but none show coronavirus subtypes like San Diego’s SEARCH
www.sandiegouniontribune.com
June 26, 2025 at 3:05 PM
Quick update on this - a good one!
Thanks to our fantastic colleagues at county HHSA, we're able to continue our wastewater surveillance work, including generating retroactive data from the last few months, as well as new data moving forward.
For how long, we'll see, but expect updates soon! 🌟❤️
Thanks to our fantastic colleagues at county HHSA, we're able to continue our wastewater surveillance work, including generating retroactive data from the last few months, as well as new data moving forward.
For how long, we'll see, but expect updates soon! 🌟❤️
Reposted by Shawn Baker
Updated a broken link in my substack post about the
#ColossalBio #DeExtinction #DisInformation campaign – dire wolves are still extinct.
open.substack.com/pub/devoevom...
#ColossalBio #DeExtinction #DisInformation campaign – dire wolves are still extinct.
open.substack.com/pub/devoevom...
The Extinction of Truth
Or, a Colossal Pile of Bullshit
open.substack.com
June 12, 2025 at 2:25 PM
Updated a broken link in my substack post about the
#ColossalBio #DeExtinction #DisInformation campaign – dire wolves are still extinct.
open.substack.com/pub/devoevom...
#ColossalBio #DeExtinction #DisInformation campaign – dire wolves are still extinct.
open.substack.com/pub/devoevom...
Illumina goes “all in” on proteomics by purchasing SomaLogic (from
Standard BioTools). Can they overtake Olink?
www.illumina.com/company/news...
Standard BioTools). Can they overtake Olink?
www.illumina.com/company/news...
Illumina to acquire SomaLogic, accelerating its proteomics business and advancing the company's multiomics strategy
www.illumina.com
June 23, 2025 at 3:35 PM
Illumina goes “all in” on proteomics by purchasing SomaLogic (from
Standard BioTools). Can they overtake Olink?
www.illumina.com/company/news...
Standard BioTools). Can they overtake Olink?
www.illumina.com/company/news...
Can't wait to listen to this one!
Had a fun chat recently with Kevin Libuit on his The Bioinformatics Lab podcast
on.soundcloud.com/2hxiS7sDlK0x...
on.soundcloud.com/2hxiS7sDlK0x...
EP 56 Open Conversation with Keith Robison
Ketih's Blog, Omics Omics: https://omicsomics.blogspot.com/
Summary
In this conversation, Keith Robison discusses the inception of his blog Omix, the evolution of social media in the scientific comm
on.soundcloud.com
June 17, 2025 at 4:54 PM
Can't wait to listen to this one!
The most charitable thing I can say about Twist’s (@twistbioscience.com) China tariff request is that it’s “unconvincing”. Tariffs aren’t the way to protect IP. This is just about making Chinese DNA more expensive.
endpoints.news/twist-biosci...
downloads.regulations.gov/BIS-2025-002...
endpoints.news/twist-biosci...
downloads.regulations.gov/BIS-2025-002...
downloads.regulations.gov
June 11, 2025 at 1:08 AM
The most charitable thing I can say about Twist’s (@twistbioscience.com) China tariff request is that it’s “unconvincing”. Tariffs aren’t the way to protect IP. This is just about making Chinese DNA more expensive.
endpoints.news/twist-biosci...
downloads.regulations.gov/BIS-2025-002...
endpoints.news/twist-biosci...
downloads.regulations.gov/BIS-2025-002...
@jaredwhitlock.bsky.social has written an article about the many new companies spun out/spawned by ex-Illuminites. In it he references the crowdsourced "Illumina Diaspora" database Millard Chan and I created to keep track of them all.
sandiegomics.com/illumina-dia...
endpts.com/how-illumina...
sandiegomics.com/illumina-dia...
endpts.com/how-illumina...
DNA giant Illumina spawned an ecosystem of competitors and customers
For Illumina, its former employees are both a boon and a problem. In the 27 years since its founding, the DNA sequencing company unlocked new frontiers in biology, medicine and ...
endpts.com
May 29, 2025 at 9:13 PM
@jaredwhitlock.bsky.social has written an article about the many new companies spun out/spawned by ex-Illuminites. In it he references the crowdsourced "Illumina Diaspora" database Millard Chan and I created to keep track of them all.
sandiegomics.com/illumina-dia...
endpts.com/how-illumina...
sandiegomics.com/illumina-dia...
endpts.com/how-illumina...
Roche has finally given their upcoming DNA sequencer a name - Axelios. So now we can stop calling it "Genia + Stratos".
www.genomeweb.com/molecular-di...
www.genomeweb.com/molecular-di...
Roche Highlights New Tests, Instrument Launches at Investor Day
The firm touted new assays, provided an update on its nanopore sequencer, and offered insights into upcoming pipeline launches.
www.genomeweb.com
May 29, 2025 at 5:37 AM
Roche has finally given their upcoming DNA sequencer a name - Axelios. So now we can stop calling it "Genia + Stratos".
www.genomeweb.com/molecular-di...
www.genomeweb.com/molecular-di...
Illumina hasn't had a lot of wins recently. I think they'd count this as a win.
endpts.com/sec-expected...
endpts.com/sec-expected...
Exclusive: SEC expected to drop investigation of Illumina's $8B Grail deal
The SEC is expected to drop an investigation into Illumina's $8 billion acquisition of cancer test developer Grail, Endpoints News has learned.
endpts.com
May 6, 2025 at 9:34 PM
Illumina hasn't had a lot of wins recently. I think they'd count this as a win.
endpts.com/sec-expected...
endpts.com/sec-expected...
This has to be one of the most "anti-science" and "anti-common sense" administrations the US has ever had. Tariffs are a tax, pure and simple and the consumer will be the one to pay the cost.
May 6, 2025 at 9:09 PM
This has to be one of the most "anti-science" and "anti-common sense" administrations the US has ever had. Tariffs are a tax, pure and simple and the consumer will be the one to pay the cost.
@twistbioscience.com is spinning out their DNA data storage tech. Atlas Data Storage is kicking off with $155M in "seed" funding 😳 That's a lot of "seed" for a market that doesn't exist yet. Best of luck! #dnasynthesis
investors.twistbioscience.com/news-release...
investors.twistbioscience.com/news-release...
investors.twistbioscience.com
May 6, 2025 at 7:26 PM
@twistbioscience.com is spinning out their DNA data storage tech. Atlas Data Storage is kicking off with $155M in "seed" funding 😳 That's a lot of "seed" for a market that doesn't exist yet. Best of luck! #dnasynthesis
investors.twistbioscience.com/news-release...
investors.twistbioscience.com/news-release...
Novartis announced a big commitment/addition to the San Diego biotech scene.
www.sandiegouniontribune.com/2025/04/10/a...
www.sandiegouniontribune.com/2025/04/10/a...
Amid tariff turmoil, Swiss drugmaker commits to build $1.1B research hub in San Diego
Novartis plans to make San Diego the center of its West Coast research hub.
www.sandiegouniontribune.com
April 12, 2025 at 1:48 AM
Novartis announced a big commitment/addition to the San Diego biotech scene.
www.sandiegouniontribune.com/2025/04/10/a...
www.sandiegouniontribune.com/2025/04/10/a...
Things just keep getting worse for ILMN. Stagnant growth, increased competition from @elembio.bsky.social and Ultima, the threat of competition from Roche SBX, and now they’re shut down in China where they get 7% of their revenue. Yikes.
www.reuters.com/business/hea...
www.reuters.com/business/hea...
China bans imports of Illumina's gene sequencers right after Trump tariff action
China announced a ban on Tuesday on imports of genetic sequencers from U.S. medical equipment maker Illumina , just minutes after U.S. President Donald Trump's additional 10% tariff on Chinese goods took effect.
www.reuters.com
March 4, 2025 at 4:23 PM
Things just keep getting worse for ILMN. Stagnant growth, increased competition from @elembio.bsky.social and Ultima, the threat of competition from Roche SBX, and now they’re shut down in China where they get 7% of their revenue. Yikes.
www.reuters.com/business/hea...
www.reuters.com/business/hea...
Reposted by Shawn Baker
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
www.nytimes.com/2025/03/01/u...
March 1, 2025 at 6:07 PM
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
www.nytimes.com/2025/03/01/u...
Wow, perhaps Tang Capital was just trying to buy Singular Genomics to shut them down for the cash. I assumed Tang was trying to combine them with other acquisitions. Glad they weren’t the winning bid.
How to eliminate biotech zombies: Buy them www.statnews.com/2025/02/27/b...
How to eliminate biotech zombies: Buy them
Why one health care investor buys “zombie” biotechs to shut them down.
www.statnews.com
February 28, 2025 at 12:32 AM
Wow, perhaps Tang Capital was just trying to buy Singular Genomics to shut them down for the cash. I assumed Tang was trying to combine them with other acquisitions. Glad they weren’t the winning bid.
Reposted by Shawn Baker
Reposted by Shawn Baker
Xenium product updates : RNA and protein multiomics workflow @10xgenomics.bsky.social #AGBT2025 #AGBT25
February 23, 2025 at 8:24 PM
Xenium product updates : RNA and protein multiomics workflow @10xgenomics.bsky.social #AGBT2025 #AGBT25
Reposted by Shawn Baker
#visiumhd product updates : segmentation , visium HD XL , visium hd 3’ @10xgenomics.bsky.social #agbt25
February 23, 2025 at 8:10 PM
#visiumhd product updates : segmentation , visium HD XL , visium hd 3’ @10xgenomics.bsky.social #agbt25
Looking forward to seeing what 10X has in store for 2025
We’re getting revved up for our pre-conference workshop this afternoon – and it’s going to be high octane. We’re starting at 1:30 PM in the Banyan ballroom. If you’re following along from home, don’t forget to tune into the livestream: bit.ly/4gB5z2g
February 23, 2025 at 5:51 PM
Looking forward to seeing what 10X has in store for 2025