Rosa HP Sca
@rosca26.bsky.social
Postdoc'ing @WashU 👩🏻🔬 AHA fellow 🫀
Rare musculoskeletal diseases & ion channels🔬
Bookworm 📚 avocaddicted 🥑 4strings lover 🎻
📍🇺🇸 🇫🇷 🇨🇱 | 🇮🇹
Rare musculoskeletal diseases & ion channels🔬
Bookworm 📚 avocaddicted 🥑 4strings lover 🎻
📍🇺🇸 🇫🇷 🇨🇱 | 🇮🇹
Reposted by Rosa HP Sca
Don’t forget to be grateful for what you DO have. The little things make life big
Image: www.instagram.com/happyvibes_w...
Image: www.instagram.com/happyvibes_w...
October 14, 2025 at 6:01 PM
Don’t forget to be grateful for what you DO have. The little things make life big
Image: www.instagram.com/happyvibes_w...
Image: www.instagram.com/happyvibes_w...
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Muscle fatigue arising intrinsically from SUR2- but not Kir6.1-dependent gain-of-function in Cantu syndrome mice. A new study from Rosa Scala, Colin Nichols et al. @colinnicholslab.bsky.social rupress.org/jgp/article/...
#IonChannels #MolecularPhysiology #Pathophysiology #SkeletalMuscle
#IonChannels #MolecularPhysiology #Pathophysiology #SkeletalMuscle
Muscle fatigue arising intrinsically from SUR2- but not Kir6.1-dependent gain-of-function in Cantu syndrome mice
We assessed skeletal muscle properties in GOF knock-in mouse models of Cantu Syndrome. In isolated myofibers there was enhanced Mg-nucleotide activation in
rupress.org
October 14, 2025 at 4:39 PM
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Reposted by Rosa HP Sca
Check out our new publication "Treatment of overactive KATP channels with glibenclamide in a zebrafish model and a clinical trial in humans with Cantú syndrome" 🧪 @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Treatment of overactive KATP channels with glibenclamide in a zebrafish model and a clinical trial in humans with Cantú syndrome - Scientific Reports
Scientific Reports - Treatment of overactive KATP channels with glibenclamide in a zebrafish model and a clinical trial in humans with Cantú syndrome
www.nature.com
October 7, 2025 at 9:05 PM
Check out our new publication "Treatment of overactive KATP channels with glibenclamide in a zebrafish model and a clinical trial in humans with Cantú syndrome" 🧪 @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Rosa HP Sca
Check out our new publication "Muscle fatigue arising intrinsically from SUR2- but not Kir6.1-dependent gain-of-function in Cantu syndrome mice" 🧪 @rosca26.bsky.social
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Scala et al. @colinnicholslab.bsky.social assess #SkeletalMuscle properties in gain-of-function knock-in mouse models of Cantu Syndrome. Isolated SUR2 GOF, but not Kir6.1 GOF muscles showed enhanced fatiguing that was reversed by the KATP channel inhibitor glibenclamide.
Muscle fatigue arising intrinsically from SUR2- but not Kir6.1-dependent gain-of-function in Cantu syndrome mice
We assessed skeletal muscle properties in GOF knock-in mouse models of Cantu Syndrome. In isolated myofibers there was enhanced Mg-nucleotide activation in
rupress.org
October 7, 2025 at 8:57 PM
Check out our new publication "Muscle fatigue arising intrinsically from SUR2- but not Kir6.1-dependent gain-of-function in Cantu syndrome mice" 🧪 @rosca26.bsky.social
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Scala et al. @colinnicholslab.bsky.social assess #SkeletalMuscle properties in gain-of-function knock-in mouse models of Cantu Syndrome. Isolated SUR2 GOF, but not Kir6.1 GOF muscles showed enhanced fatiguing that was reversed by the KATP channel inhibitor glibenclamide.
Muscle fatigue arising intrinsically from SUR2- but not Kir6.1-dependent gain-of-function in Cantu syndrome mice
We assessed skeletal muscle properties in GOF knock-in mouse models of Cantu Syndrome. In isolated myofibers there was enhanced Mg-nucleotide activation in
rupress.org
October 7, 2025 at 8:22 PM
Reposted by Rosa HP Sca
Check out our new publication "Paradoxical Maturity-Onset Diabetes of the Young Arising From Loss-of-Function Mutations in ATP-Sensitive Potassium Channels" 🧪 diabetesjournals.org/diabetes/art... @rosca26.bsky.social
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Paradoxical Maturity-Onset Diabetes of the Young Arising From Loss-of-Function Mutations in ATP-Sensitive Potassium Channels
Pancreatic β-cell ATP-sensitive K+ (KATP) channel closure underlies electrical excitability and insulin release, but loss or inhibition of KATP channels ca
diabetesjournals.org
May 22, 2025 at 6:56 PM
Check out our new publication "Paradoxical Maturity-Onset Diabetes of the Young Arising From Loss-of-Function Mutations in ATP-Sensitive Potassium Channels" 🧪 diabetesjournals.org/diabetes/art... @rosca26.bsky.social
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Reposted by Rosa HP Sca
Next Monday! 🧪
May 17, 2025 at 1:44 PM
Next Monday! 🧪
Reposted by Rosa HP Sca
Join us today for a new exciting CIMED seminar! 🧪 @osamaharraz.bsky.social
May 5, 2025 at 3:13 PM
Join us today for a new exciting CIMED seminar! 🧪 @osamaharraz.bsky.social
Reposted by Rosa HP Sca
Join us today for a new exciting CIMED seminar! 🧪
April 7, 2025 at 3:24 PM
Join us today for a new exciting CIMED seminar! 🧪
Reposted by Rosa HP Sca
Reposted by Rosa HP Sca
“"What we've shown in this paper is that the epithelial cells can communicate with the macrophages,"… "Our hypothesis is that their cross talk potentially provides an environment that's conducive to the development of the disease."
🧪 #ReproSky #MedSky #ObGynSky
medicalxpress.com/news/2025-03...
🧪 #ReproSky #MedSky #ObGynSky
medicalxpress.com/news/2025-03...
Researchers make progress toward non-hormonal treatment for endometriosis
Roughly 200 million women around the world suffer from endometriosis, a condition that causes tissue from the lining of the uterus to grow in places outside of the uterus. The condition can be excepti...
medicalxpress.com
March 23, 2025 at 2:35 AM
“"What we've shown in this paper is that the epithelial cells can communicate with the macrophages,"… "Our hypothesis is that their cross talk potentially provides an environment that's conducive to the development of the disease."
🧪 #ReproSky #MedSky #ObGynSky
medicalxpress.com/news/2025-03...
🧪 #ReproSky #MedSky #ObGynSky
medicalxpress.com/news/2025-03...
Reposted by Rosa HP Sca
To celebrate the Biophysics Week, the Spanish Biophysical Society has coordinated a series of "Biophyzza Connection" Affiliate Events locally organized by its members and sponsored by Domino’s Pizza. Explore and find an event close to you!
The Biophyzza Connection 2025 | Spanish Biophysical Society
buff.ly
March 22, 2025 at 10:02 AM
To celebrate the Biophysics Week, the Spanish Biophysical Society has coordinated a series of "Biophyzza Connection" Affiliate Events locally organized by its members and sponsored by Domino’s Pizza. Explore and find an event close to you!
Reposted by Rosa HP Sca
🔔Join us on 25 March to discuss the green steel transition!
#EuropeanSteel is at a crossroads:
🔥 Stick with outdated, coal-based tech
💚 Upgrade to #GreenSteel & boost #recycling
Register 👇
www.eventbrite.com/e/report-lau...
@e3g.bsky.social @beyondfossilfuels.bsky.social
#EuropeanSteel is at a crossroads:
🔥 Stick with outdated, coal-based tech
💚 Upgrade to #GreenSteel & boost #recycling
Register 👇
www.eventbrite.com/e/report-lau...
@e3g.bsky.social @beyondfossilfuels.bsky.social
March 20, 2025 at 8:40 AM
🔔Join us on 25 March to discuss the green steel transition!
#EuropeanSteel is at a crossroads:
🔥 Stick with outdated, coal-based tech
💚 Upgrade to #GreenSteel & boost #recycling
Register 👇
www.eventbrite.com/e/report-lau...
@e3g.bsky.social @beyondfossilfuels.bsky.social
#EuropeanSteel is at a crossroads:
🔥 Stick with outdated, coal-based tech
💚 Upgrade to #GreenSteel & boost #recycling
Register 👇
www.eventbrite.com/e/report-lau...
@e3g.bsky.social @beyondfossilfuels.bsky.social
Reposted by Rosa HP Sca
March 20th is the UN International Day of Happiness. This year’s theme is 'Caring and Sharing' and we’re encouraging 1 million extra acts of caring and sharing. You can be part of it! Please help spread the word 🙏💕🌎 #InternationalDayOfHappiness dayofhappiness.net
International Day of Happiness - 20 March
Celebrate #InternationalDayOfHappiness on 20 March. Join the Action for Happiness community and help create a happier and kinder world, together.
dayofhappiness.net
March 19, 2025 at 11:13 PM
March 20th is the UN International Day of Happiness. This year’s theme is 'Caring and Sharing' and we’re encouraging 1 million extra acts of caring and sharing. You can be part of it! Please help spread the word 🙏💕🌎 #InternationalDayOfHappiness dayofhappiness.net
Reposted by Rosa HP Sca
Happy #StPatricksDay! ☘️
What makes the bubbles in a glass of Guinness fall, and what gives the beer its dark colour?
This graphic in @cenmag.bsky.social has the answers: cen.acs.org/articles/93/...
#ChemSky 🧪
What makes the bubbles in a glass of Guinness fall, and what gives the beer its dark colour?
This graphic in @cenmag.bsky.social has the answers: cen.acs.org/articles/93/...
#ChemSky 🧪
March 17, 2025 at 3:43 PM
Happy #StPatricksDay! ☘️
What makes the bubbles in a glass of Guinness fall, and what gives the beer its dark colour?
This graphic in @cenmag.bsky.social has the answers: cen.acs.org/articles/93/...
#ChemSky 🧪
What makes the bubbles in a glass of Guinness fall, and what gives the beer its dark colour?
This graphic in @cenmag.bsky.social has the answers: cen.acs.org/articles/93/...
#ChemSky 🧪
«Ridateci la Statua della Libertà» www.ilpost.it/2025/03/17/r...
«Ridateci la Statua della Libertà» - Il Post
Lo ha chiesto un politico francese criticando le politiche di Donald Trump contro la ricerca scientifica
www.ilpost.it
March 17, 2025 at 12:54 PM
«Ridateci la Statua della Libertà» www.ilpost.it/2025/03/17/r...
Reposted by Rosa HP Sca
I just read this study on using humor to be a better science communicator. What's your favorite use of humor in a paper or talk? Here's one related to my field. jcom.sissa.it/article/pubi... 🧪
March 17, 2025 at 11:18 AM
I just read this study on using humor to be a better science communicator. What's your favorite use of humor in a paper or talk? Here's one related to my field. jcom.sissa.it/article/pubi... 🧪
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Check out our new publication "Dynein light chains 1 and 2 are auxiliary proteins of pH-sensitive Kir4.1 channels"
www.sciencedirect.com/science/arti...
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www.sciencedirect.com/science/arti...
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Dynein light chains 1 and 2 are auxiliary proteins of pH-sensitive Kir4.1 channels
Inward rectifier Kir4.1 potassium channels are abundantly expressed in cells that are important for electrolyte homeostasis. Dysregulation of Kir4.1 u…
www.sciencedirect.com
March 15, 2025 at 5:23 PM
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Reposted by Rosa HP Sca
If you don’t get your child vaccinated against measles, it can put them at a high risk of this serious infection, which can lead to severe complications or even death.
Make sure your child’s measles vaccination is up to date.
Make sure your child’s measles vaccination is up to date.
March 14, 2025 at 12:18 PM
If you don’t get your child vaccinated against measles, it can put them at a high risk of this serious infection, which can lead to severe complications or even death.
Make sure your child’s measles vaccination is up to date.
Make sure your child’s measles vaccination is up to date.
@standupforscience.bsky.social in Jefferson City MO 🧪👩🏻🔬🥼🔬 www.stlpr.org/government-p...
SLU, WashU researchers among those at state Capitol protesting science funding cuts
The protest was organized as part of a nationwide Stand Up for Science effort, with thousands gathering at dozens of rallies across the country.
www.stlpr.org
March 8, 2025 at 3:17 PM
@standupforscience.bsky.social in Jefferson City MO 🧪👩🏻🔬🥼🔬 www.stlpr.org/government-p...
@standupforscience.bsky.social in St. Louis MO 🧪👩🏻🔬🥼🔬 www.stltoday.com/news/local/m...
St. Louis joins nation in 'Stand Up For Science' protests
Researchers, doctors, patients and supporters ventured out of labs, hospitals and offices Friday to fight against what they call a blitz on life-saving science by the Trump administration.
www.stltoday.com
March 8, 2025 at 1:03 PM
@standupforscience.bsky.social in St. Louis MO 🧪👩🏻🔬🥼🔬 www.stltoday.com/news/local/m...
Reposted by Rosa HP Sca
At @standupforscience.bsky.social and the signs are statistically significantly excellent
March 7, 2025 at 6:51 PM
At @standupforscience.bsky.social and the signs are statistically significantly excellent
Reposted by Rosa HP Sca
March 7, 2025 at 5:08 PM
Reposted by Rosa HP Sca
TODAY IS THE DAY! 🧪☀️⬇️
Join us at the Lincoln Memorial or your local site to Stand Up for Science!
Join us at the Lincoln Memorial or your local site to Stand Up for Science!
March 7, 2025 at 11:44 AM
TODAY IS THE DAY! 🧪☀️⬇️
Join us at the Lincoln Memorial or your local site to Stand Up for Science!
Join us at the Lincoln Memorial or your local site to Stand Up for Science!
Reposted by Rosa HP Sca
Join us today for a new exciting CIMED seminar! 🧪
March 3, 2025 at 4:15 PM
Join us today for a new exciting CIMED seminar! 🧪