Rhys Parry
@rhyshparry.bsky.social
Virologist at the University of Queensland. #virology #virusevolution #rnavirology
Reposted by Rhys Parry
🚨 NEW: The majority holder of the world's genetic sequence data is a bad actor who can cut off access to critics and competing services. We've tolerated this for years, and now it threatens the pandemic treaty. Time for WHO to step in. With @ctrlalttim.com: www.thinkglobalhealth.org/article/to-f...
To Finish the Pandemic Agreement, WHO Needs a Trustworthy Viral Database | Think Global Health
Online platforms for sharing virus sequences are in disarray. The World Health Organization has a chance to build something new
www.thinkglobalhealth.org
November 5, 2025 at 3:31 PM
🚨 NEW: The majority holder of the world's genetic sequence data is a bad actor who can cut off access to critics and competing services. We've tolerated this for years, and now it threatens the pandemic treaty. Time for WHO to step in. With @ctrlalttim.com: www.thinkglobalhealth.org/article/to-f...
Reposted by Rhys Parry
I want to spell this out in case the implications aren't clear:
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
On Oct 1, 2025, GISAID informed us that they had ended updates to the flat file of SARS-CoV-2 genomic sequences and associated metadata that we had used to update Nextstrain analyses since Feb 2020. GISAID's stated rationale was that their "resources are limited". 1/5
November 7, 2025 at 2:41 PM
I want to spell this out in case the implications aren't clear:
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
Reposted by Rhys Parry
🧬 MiM2025 — ASM Queensland Annual Meeting
Join us for a full day of microbiology at Griffith Uni, Gold Coast!
📅 Sat 22 Nov 2025 | Free for members
🎙 Featuring keynote speakers Greg Cook, @duckswabber.bsky.social Michelle Wille & Subir Sarker.
🔗 Register: www.trybooking.com/DGRHL
#ASM #Micro #MiM2025
Join us for a full day of microbiology at Griffith Uni, Gold Coast!
📅 Sat 22 Nov 2025 | Free for members
🎙 Featuring keynote speakers Greg Cook, @duckswabber.bsky.social Michelle Wille & Subir Sarker.
🔗 Register: www.trybooking.com/DGRHL
#ASM #Micro #MiM2025
October 23, 2025 at 12:49 AM
🧬 MiM2025 — ASM Queensland Annual Meeting
Join us for a full day of microbiology at Griffith Uni, Gold Coast!
📅 Sat 22 Nov 2025 | Free for members
🎙 Featuring keynote speakers Greg Cook, @duckswabber.bsky.social Michelle Wille & Subir Sarker.
🔗 Register: www.trybooking.com/DGRHL
#ASM #Micro #MiM2025
Join us for a full day of microbiology at Griffith Uni, Gold Coast!
📅 Sat 22 Nov 2025 | Free for members
🎙 Featuring keynote speakers Greg Cook, @duckswabber.bsky.social Michelle Wille & Subir Sarker.
🔗 Register: www.trybooking.com/DGRHL
#ASM #Micro #MiM2025
Had a wonderful time at #HCVFLAVI2025 in Singapore presenting our Flavi ncRNA work from the Khromykh lab and was chuffed to pick up a short talk award. Here I am with other awardees demonstrating a normal distribution. Hope to see you again at #HCVFLAVI2026
October 18, 2025 at 6:05 AM
Had a wonderful time at #HCVFLAVI2025 in Singapore presenting our Flavi ncRNA work from the Khromykh lab and was chuffed to pick up a short talk award. Here I am with other awardees demonstrating a normal distribution. Hope to see you again at #HCVFLAVI2026
Final day of #HCFLAVI2025 with a great talk from @maringerlab.bsky.social on 3D models of dengue microvascular dysfunction, using gorgeous liver microvascular spheroids, to unpack #dengue vascular pathology.
October 16, 2025 at 2:07 AM
Final day of #HCFLAVI2025 with a great talk from @maringerlab.bsky.social on 3D models of dengue microvascular dysfunction, using gorgeous liver microvascular spheroids, to unpack #dengue vascular pathology.
Reposted by Rhys Parry
🚨 SAVE THE DATE 🚨
MiM2025 — ASM QLD’s annual microbiology meeting 🧫✨
📍 Gold Coast | 🗓️ 22 Nov 2025
🧪 Talks & 5-min #Microbites for students
📨 Abstracts due 20 Oct — send to qldbranch@theasm.org.au
@aussocmic.bsky.social
#MiM2025 #microbiology
MiM2025 — ASM QLD’s annual microbiology meeting 🧫✨
📍 Gold Coast | 🗓️ 22 Nov 2025
🧪 Talks & 5-min #Microbites for students
📨 Abstracts due 20 Oct — send to qldbranch@theasm.org.au
@aussocmic.bsky.social
#MiM2025 #microbiology
October 2, 2025 at 5:40 AM
🚨 SAVE THE DATE 🚨
MiM2025 — ASM QLD’s annual microbiology meeting 🧫✨
📍 Gold Coast | 🗓️ 22 Nov 2025
🧪 Talks & 5-min #Microbites for students
📨 Abstracts due 20 Oct — send to qldbranch@theasm.org.au
@aussocmic.bsky.social
#MiM2025 #microbiology
MiM2025 — ASM QLD’s annual microbiology meeting 🧫✨
📍 Gold Coast | 🗓️ 22 Nov 2025
🧪 Talks & 5-min #Microbites for students
📨 Abstracts due 20 Oct — send to qldbranch@theasm.org.au
@aussocmic.bsky.social
#MiM2025 #microbiology
Haunted lately by @galaxyproject.bsky.social CO₂e estimates for jobs. This one MEGAHIT assembly: ~450g CO2e. I've run this ~150k times on HPC, ~75 tonnes of CO2e 😬. Perhaps ARC/NHMRC would accept Australian Carbon Credit Units as part of the grant cost for offset? What others are doing in AUS/INT?
October 6, 2025 at 3:55 AM
Haunted lately by @galaxyproject.bsky.social CO₂e estimates for jobs. This one MEGAHIT assembly: ~450g CO2e. I've run this ~150k times on HPC, ~75 tonnes of CO2e 😬. Perhaps ARC/NHMRC would accept Australian Carbon Credit Units as part of the grant cost for offset? What others are doing in AUS/INT?
Reposted by Rhys Parry
🌟 Thrilled to share that my lab’s first publication is now out in @natmetabolism.nature.com. Congrats to the team 🎉
🧠 We discovered that neurons use endogenous fatty acids as an energy fuel, challenging long-standing models of sugars being the exclusive energy source for neurons. 1/3
🧠 We discovered that neurons use endogenous fatty acids as an energy fuel, challenging long-standing models of sugars being the exclusive energy source for neurons. 1/3
October 1, 2025 at 4:11 AM
🌟 Thrilled to share that my lab’s first publication is now out in @natmetabolism.nature.com. Congrats to the team 🎉
🧠 We discovered that neurons use endogenous fatty acids as an energy fuel, challenging long-standing models of sugars being the exclusive energy source for neurons. 1/3
🧠 We discovered that neurons use endogenous fatty acids as an energy fuel, challenging long-standing models of sugars being the exclusive energy source for neurons. 1/3
Reposted by Rhys Parry
New preprint alert! 🦟 <-> 🦠 <-> 🧑
I am thrilled to share our latest study on alphavirus host adaptation. More specifically, on how a single codon helps blunt alphavirus-induced host innate immune responses in mosquito and human cells. Continue reading for more!
www.biorxiv.org/content/10.1...
I am thrilled to share our latest study on alphavirus host adaptation. More specifically, on how a single codon helps blunt alphavirus-induced host innate immune responses in mosquito and human cells. Continue reading for more!
www.biorxiv.org/content/10.1...
The Sindbis virus nsP3 opal codon protects viral RNA and fitness by maintaining replication spherule integrity
Most alphaviruses encode an in-frame opal stop codon between nsP3 and nsP4 in their nsP ORF. This opal stop codon mediates a temperature-dependent balance between viral polymerase production and prote...
www.biorxiv.org
September 29, 2025 at 11:23 AM
New preprint alert! 🦟 <-> 🦠 <-> 🧑
I am thrilled to share our latest study on alphavirus host adaptation. More specifically, on how a single codon helps blunt alphavirus-induced host innate immune responses in mosquito and human cells. Continue reading for more!
www.biorxiv.org/content/10.1...
I am thrilled to share our latest study on alphavirus host adaptation. More specifically, on how a single codon helps blunt alphavirus-induced host innate immune responses in mosquito and human cells. Continue reading for more!
www.biorxiv.org/content/10.1...
Reposted by Rhys Parry
🚨 New Web Resource Alert! 🚨 We're delighted to share Viro3D a database of >85000 viral protein structure predictions from >4400 human & animal viruses.
🔗 viro3d.cvr.gla.ac.uk
📄 www.embopress.org/doi/full/10....
@molsystbiol.org @cvrinfo.bsky.social @uofgmvls.bsky.social #Virology #AlphaFold 🧪 🦠
🔗 viro3d.cvr.gla.ac.uk
📄 www.embopress.org/doi/full/10....
@molsystbiol.org @cvrinfo.bsky.social @uofgmvls.bsky.social #Virology #AlphaFold 🧪 🦠
Viro3D
viro3d.cvr.gla.ac.uk
September 26, 2025 at 11:36 AM
🚨 New Web Resource Alert! 🚨 We're delighted to share Viro3D a database of >85000 viral protein structure predictions from >4400 human & animal viruses.
🔗 viro3d.cvr.gla.ac.uk
📄 www.embopress.org/doi/full/10....
@molsystbiol.org @cvrinfo.bsky.social @uofgmvls.bsky.social #Virology #AlphaFold 🧪 🦠
🔗 viro3d.cvr.gla.ac.uk
📄 www.embopress.org/doi/full/10....
@molsystbiol.org @cvrinfo.bsky.social @uofgmvls.bsky.social #Virology #AlphaFold 🧪 🦠
Congrats to @summabibby.bsky.social @naphakm.bsky.social Daniel Watterson et al. here at SCMB on the first high-res cryo-EM structures of yellow fever virus! Striking vaccine vs virulent particle differences and a single R380 residue shaping antigenicity & neutralisation. doi.org/10.1038/s414...
September 27, 2025 at 3:31 AM
Congrats to @summabibby.bsky.social @naphakm.bsky.social Daniel Watterson et al. here at SCMB on the first high-res cryo-EM structures of yellow fever virus! Striking vaccine vs virulent particle differences and a single R380 residue shaping antigenicity & neutralisation. doi.org/10.1038/s414...
The use of attenuated SC2 JN.1 as a bivalent vaccine vector. Mutate (D130A) in nsp16, delete FCS in spike, delete accessory ORFs, and/or modify transcription regulatory sequences, then add prefusion RSV F. Successfully protects, although modified TRS seem to over-attenuate. doi.org/10.1126/scia...
September 27, 2025 at 3:22 AM
The use of attenuated SC2 JN.1 as a bivalent vaccine vector. Mutate (D130A) in nsp16, delete FCS in spike, delete accessory ORFs, and/or modify transcription regulatory sequences, then add prefusion RSV F. Successfully protects, although modified TRS seem to over-attenuate. doi.org/10.1126/scia...
Reposted by Rhys Parry
🧪🦠🖥️🧬🧫🔬 The Roadmap for equitable use of public microbiome data -including the Data Reuse Information Tag (DRI)- by the #DataReuseConsortium.
Must read if you use or produce microbiome data!
Kudos to the Data Reuse Core Team for their hard work!
doi.org/10.1038/s415...
Must read if you use or produce microbiome data!
Kudos to the Data Reuse Core Team for their hard work!
doi.org/10.1038/s415...
September 26, 2025 at 11:24 AM
🧪🦠🖥️🧬🧫🔬 The Roadmap for equitable use of public microbiome data -including the Data Reuse Information Tag (DRI)- by the #DataReuseConsortium.
Must read if you use or produce microbiome data!
Kudos to the Data Reuse Core Team for their hard work!
doi.org/10.1038/s415...
Must read if you use or produce microbiome data!
Kudos to the Data Reuse Core Team for their hard work!
doi.org/10.1038/s415...
Establishment of reverse genetics systems for Colorado tick fever virus. Remind me never to complain about monopartite reverse genetics systems.
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
September 25, 2025 at 6:34 AM
Establishment of reverse genetics systems for Colorado tick fever virus. Remind me never to complain about monopartite reverse genetics systems.
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Impressive work on the effect of #Wolbachia in 60! strains of DENV. Like earlier reports, DENV-1,2,4 was strongly inhibited. DENV-3 isolates had more variable & weaker inhibition.
Given the range of genotypes, this is a strong foundation to examine viral genetic determinants of susceptibility.
Given the range of genotypes, this is a strong foundation to examine viral genetic determinants of susceptibility.
September 22, 2025 at 1:43 AM
Impressive work on the effect of #Wolbachia in 60! strains of DENV. Like earlier reports, DENV-1,2,4 was strongly inhibited. DENV-3 isolates had more variable & weaker inhibition.
Given the range of genotypes, this is a strong foundation to examine viral genetic determinants of susceptibility.
Given the range of genotypes, this is a strong foundation to examine viral genetic determinants of susceptibility.
Reposted by Rhys Parry
Transcriptomic response of mosquitoes to Japanese encephalitis virus and identification of its potential entry factors
www.nature.com/articles/s44...
www.nature.com/articles/s44...
Transcriptomic response of mosquitoes to Japanese encephalitis virus and identification of its potential entry factors - npj Viruses
npj Viruses - Transcriptomic response of mosquitoes to Japanese encephalitis virus and identification of its potential entry factors
www.nature.com
September 12, 2025 at 2:54 PM
Transcriptomic response of mosquitoes to Japanese encephalitis virus and identification of its potential entry factors
www.nature.com/articles/s44...
www.nature.com/articles/s44...
Reposted by Rhys Parry
How can mosquitoes tolerate viral infections?
In our latest preprint we show that mosquitoes that can regulate their metabolism after infection can tolerate viral infections better.
Thanks to all the authors for all your ideas and contributions
www.biorxiv.org/content/10.1...
In our latest preprint we show that mosquitoes that can regulate their metabolism after infection can tolerate viral infections better.
Thanks to all the authors for all your ideas and contributions
www.biorxiv.org/content/10.1...
Metabolic homeostasis favors tolerance to persistent viral infection in Aedes aegypti mosquitoes
The mosquito Aedes aegypti harbors a wide range of persistent viral infections, including both medically important arboviruses and insect-specific viruses (ISVs). However, the mechanisms underpinning ...
www.biorxiv.org
July 29, 2025 at 12:32 PM
How can mosquitoes tolerate viral infections?
In our latest preprint we show that mosquitoes that can regulate their metabolism after infection can tolerate viral infections better.
Thanks to all the authors for all your ideas and contributions
www.biorxiv.org/content/10.1...
In our latest preprint we show that mosquitoes that can regulate their metabolism after infection can tolerate viral infections better.
Thanks to all the authors for all your ideas and contributions
www.biorxiv.org/content/10.1...
Reposted by Rhys Parry
🚨Call for abstracts
#OneHealth Aotearoa Symposium 2025
📍Wellington + online
🗓️2–3 Dec 2025
Submit an abstract by 30 Sept
Themes: #AMR, #Zoonoses, #HealthEquity, #TeAoMāori, #ClimateHealth & more
More info👉 onehealth.org.nz/one-health-a...
📩one.health@otago.ac.nz
🖥️🧬💻
#AcademicSky
#MicroSky
🧪🧫🦠
#OneHealth Aotearoa Symposium 2025
📍Wellington + online
🗓️2–3 Dec 2025
Submit an abstract by 30 Sept
Themes: #AMR, #Zoonoses, #HealthEquity, #TeAoMāori, #ClimateHealth & more
More info👉 onehealth.org.nz/one-health-a...
📩one.health@otago.ac.nz
🖥️🧬💻
#AcademicSky
#MicroSky
🧪🧫🦠
One Health Aotearoa Symposium 2025 - One Health Aotearoa
Our 11th annual symposium will be held on 2-3 December 2025 at the University of Otago, Wellington campus and online. Registrations will open soon! Venue Information Nordmeyer Lecture Theatre – Univer...
onehealth.org.nz
September 11, 2025 at 7:51 AM
🚨Call for abstracts
#OneHealth Aotearoa Symposium 2025
📍Wellington + online
🗓️2–3 Dec 2025
Submit an abstract by 30 Sept
Themes: #AMR, #Zoonoses, #HealthEquity, #TeAoMāori, #ClimateHealth & more
More info👉 onehealth.org.nz/one-health-a...
📩one.health@otago.ac.nz
🖥️🧬💻
#AcademicSky
#MicroSky
🧪🧫🦠
#OneHealth Aotearoa Symposium 2025
📍Wellington + online
🗓️2–3 Dec 2025
Submit an abstract by 30 Sept
Themes: #AMR, #Zoonoses, #HealthEquity, #TeAoMāori, #ClimateHealth & more
More info👉 onehealth.org.nz/one-health-a...
📩one.health@otago.ac.nz
🖥️🧬💻
#AcademicSky
#MicroSky
🧪🧫🦠
Reposted by Rhys Parry
Until next year, @mozztacular.bsky.social, Asad, @royalfizzbin.bsky.social, Mozammel, @wytamma.bsky.social , Bec, and @rhyshparry.bsky.social out!
#MicroSeq2025
#MicroSeq2025
September 4, 2025 at 6:49 AM
Until next year, @mozztacular.bsky.social, Asad, @royalfizzbin.bsky.social, Mozammel, @wytamma.bsky.social , Bec, and @rhyshparry.bsky.social out!
#MicroSeq2025
#MicroSeq2025
Reposted by Rhys Parry
Our research describing the isolation and characterisation of a novel henipavirus, Salt Gully virus, discovered in Australian bats has been published in the September edition of Emerging Infectious Diseases.
wwwnc.cdc.gov/eid/article/...
wwwnc.cdc.gov/eid/article/...
Novel Henipavirus, Salt Gully Virus, Isolated from Pteropid Bats, Australia
Novel Henipavirus Isolated from Bats, Australia
wwwnc.cdc.gov
September 2, 2025 at 9:47 PM
Our research describing the isolation and characterisation of a novel henipavirus, Salt Gully virus, discovered in Australian bats has been published in the September edition of Emerging Infectious Diseases.
wwwnc.cdc.gov/eid/article/...
wwwnc.cdc.gov/eid/article/...
Reposted by Rhys Parry
Your #MicroSeq2025 committee - @mozztacular.bsky.social , Asad Prodhan, @royalfizzbin.bsky.social , Mozammel Hoque, @wytamma.bsky.social , Rebecca Roach, and @rhyshparry.bsky.social - are all here and ready to go! 🫡
Please feel free to reach out to any of us w/ questions or concerns at any time ♥️
Please feel free to reach out to any of us w/ questions or concerns at any time ♥️
September 3, 2025 at 12:31 AM
Your #MicroSeq2025 committee - @mozztacular.bsky.social , Asad Prodhan, @royalfizzbin.bsky.social , Mozammel Hoque, @wytamma.bsky.social , Rebecca Roach, and @rhyshparry.bsky.social - are all here and ready to go! 🫡
Please feel free to reach out to any of us w/ questions or concerns at any time ♥️
Please feel free to reach out to any of us w/ questions or concerns at any time ♥️
Reposted by Rhys Parry
✨ #MicroSeq2025 Plenary Highlight! ✨
Dr Jackie Mahar is an evolutionary virologist & bioinformatician based at CSIRO, managing projects on NGS-based phylogenomics of zoonotic & animal viruses for pathogen discovery, surveillance & viral ecology.
Register👇
trybooking.com/events/landing/1424679
Dr Jackie Mahar is an evolutionary virologist & bioinformatician based at CSIRO, managing projects on NGS-based phylogenomics of zoonotic & animal viruses for pathogen discovery, surveillance & viral ecology.
Register👇
trybooking.com/events/landing/1424679
September 1, 2025 at 4:42 AM
✨ #MicroSeq2025 Plenary Highlight! ✨
Dr Jackie Mahar is an evolutionary virologist & bioinformatician based at CSIRO, managing projects on NGS-based phylogenomics of zoonotic & animal viruses for pathogen discovery, surveillance & viral ecology.
Register👇
trybooking.com/events/landing/1424679
Dr Jackie Mahar is an evolutionary virologist & bioinformatician based at CSIRO, managing projects on NGS-based phylogenomics of zoonotic & animal viruses for pathogen discovery, surveillance & viral ecology.
Register👇
trybooking.com/events/landing/1424679
Reposted by Rhys Parry
RNAi is a powerful tool for mosquito control, but delivery remains difficult.
Could symbiotic bacteria be the key? Mixed results so far highlight the complexity and the gaps in our understanding of RNAi, bacterial delivery, and host–symbiont interactions.
Read more in our recent review👇
Could symbiotic bacteria be the key? Mixed results so far highlight the complexity and the gaps in our understanding of RNAi, bacterial delivery, and host–symbiont interactions.
Read more in our recent review👇
August 25, 2025 at 12:59 PM
RNAi is a powerful tool for mosquito control, but delivery remains difficult.
Could symbiotic bacteria be the key? Mixed results so far highlight the complexity and the gaps in our understanding of RNAi, bacterial delivery, and host–symbiont interactions.
Read more in our recent review👇
Could symbiotic bacteria be the key? Mixed results so far highlight the complexity and the gaps in our understanding of RNAi, bacterial delivery, and host–symbiont interactions.
Read more in our recent review👇
Reposted by Rhys Parry
We are delighted to announce our plenary speakers for #MicroSeq2025! Dr Rose Collis, Dr Jackie Mahar, Dr Peter Mee, and Dr Leah Roberts! We’ll be treated to four excellent talks across September 3-4. We can’t wait! Register below👇
trybooking.com/events/landing/1424679
trybooking.com/events/landing/1424679
August 7, 2025 at 2:37 AM
We are delighted to announce our plenary speakers for #MicroSeq2025! Dr Rose Collis, Dr Jackie Mahar, Dr Peter Mee, and Dr Leah Roberts! We’ll be treated to four excellent talks across September 3-4. We can’t wait! Register below👇
trybooking.com/events/landing/1424679
trybooking.com/events/landing/1424679
Reposted by Rhys Parry
What crap is this?
"The Queensland government says it wasn't "confident" a doctor was suitable to be the state's chief health officer"
-do they not know the last 2 two Qld CHOs were medical doctors (and so stand-ins)?? The need is in the title guys.
www.abc.net.au/news/2025-08...
"The Queensland government says it wasn't "confident" a doctor was suitable to be the state's chief health officer"
-do they not know the last 2 two Qld CHOs were medical doctors (and so stand-ins)?? The need is in the title guys.
www.abc.net.au/news/2025-08...
MP calls for transparency over Qld health head appointment
Sources told the ABC an offer for the state's top health job was made and quickly scrapped.
www.abc.net.au
August 14, 2025 at 10:46 PM
What crap is this?
"The Queensland government says it wasn't "confident" a doctor was suitable to be the state's chief health officer"
-do they not know the last 2 two Qld CHOs were medical doctors (and so stand-ins)?? The need is in the title guys.
www.abc.net.au/news/2025-08...
"The Queensland government says it wasn't "confident" a doctor was suitable to be the state's chief health officer"
-do they not know the last 2 two Qld CHOs were medical doctors (and so stand-ins)?? The need is in the title guys.
www.abc.net.au/news/2025-08...