Ranier Gutierrez
@raniergutierrez.bsky.social
Scientist, study taste and the neural control of appetite. I go wherever curiosity may lead me. I photograph the extraordinary of ordinary life
https://scholar.google.com.mx/citations?user=o4ujbjQAAAAJ&hl=es
https://scholar.google.com.mx/citations?user=o4ujbjQAAAAJ&hl=es
Pinned
doi.org
The Crunchometer is a low-cost, open-source technology that uses bite sound to democratize the microstructural analysis of feeding bouts on solid food: 🧪
The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure.
doi.org/10.7554/eLif...
The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure.
doi.org/10.7554/eLif...
The Crunchometer is a low-cost, open-source technology that uses bite sound to democratize the microstructural analysis of feeding bouts on solid food: 🧪
The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure.
doi.org/10.7554/eLif...
The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure.
doi.org/10.7554/eLif...
doi.org
November 3, 2025 at 12:01 AM
The Crunchometer is a low-cost, open-source technology that uses bite sound to democratize the microstructural analysis of feeding bouts on solid food: 🧪
The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure.
doi.org/10.7554/eLif...
The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure.
doi.org/10.7554/eLif...
Reposted by Ranier Gutierrez
The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure https://www.biorxiv.org/content/10.1101/2025.07.25.666891v1
July 31, 2025 at 5:17 PM
The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure https://www.biorxiv.org/content/10.1101/2025.07.25.666891v1
A new paper from the laboratory Neurobiology of Appetite at Cinvestav. We introduced the OptoDrive! To record and optogenetically stimulate the brain of freely moving mice
www.eneuro.org/content/12/6...
www.eneuro.org/content/12/6...
Automatic OptoDrive for Extracellular Recordings and Optogenetic Stimulation in Freely Moving Mice
Extracellular recordings in freely moving mice, especially those with movable electrodes (microdrives), are crucial for understanding brain function. However, existing microdrives are often heavy, exp...
www.eneuro.org
June 26, 2025 at 8:42 PM
A new paper from the laboratory Neurobiology of Appetite at Cinvestav. We introduced the OptoDrive! To record and optogenetically stimulate the brain of freely moving mice
www.eneuro.org/content/12/6...
www.eneuro.org/content/12/6...
A new paper out of Laboratory Neurobiology of Appetite! Developing an automatic algorithm to detect head weaving stereotypes induced by DA appetite suppressants
journals.plos.org/plosone/arti...
journals.plos.org/plosone/arti...
Sex-specific effects of appetite suppressants on stereotypy in rats
This study investigated the sex-specific effects of commonly prescribed appetite suppressants on body weight and the manifestation of motor side effects, specifically stereotypy. Employing video recor...
journals.plos.org
June 25, 2025 at 3:51 PM
A new paper out of Laboratory Neurobiology of Appetite! Developing an automatic algorithm to detect head weaving stereotypes induced by DA appetite suppressants
journals.plos.org/plosone/arti...
journals.plos.org/plosone/arti...
Reposted by Ranier Gutierrez
A nice write up about the new work coming out of the Rutgers Center for NeuroMetabolism www.rutgers.edu/news/two-rut...
Two Rutgers Teams Trace Brain Circuits That Tell Us When to Eat – and When to Stop
Back-to-back studies map complementary hunger and satiety pathways, offering clues to refine weight-loss drugs.
www.rutgers.edu
June 10, 2025 at 4:50 PM
A nice write up about the new work coming out of the Rutgers Center for NeuroMetabolism www.rutgers.edu/news/two-rut...
Reposted by Ranier Gutierrez
Excited to share our latest story: "The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events" 🎉.
Big congrats to 1st author Oriane Onimus 💪 🥳 & many thanks to all those involved 🙏🙏.
www.biorxiv.org/content/10.1...
Big congrats to 1st author Oriane Onimus 💪 🥳 & many thanks to all those involved 🙏🙏.
www.biorxiv.org/content/10.1...
The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events
Reward-related processes have traditionally been ascribed to neural circuits centered on the dopamine (DA) system. While exteroceptive stimuli, such as food and drugs of abuse, are well-established ac...
www.biorxiv.org
May 16, 2025 at 8:41 AM
Excited to share our latest story: "The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events" 🎉.
Big congrats to 1st author Oriane Onimus 💪 🥳 & many thanks to all those involved 🙏🙏.
www.biorxiv.org/content/10.1...
Big congrats to 1st author Oriane Onimus 💪 🥳 & many thanks to all those involved 🙏🙏.
www.biorxiv.org/content/10.1...
Reposted by Ranier Gutierrez
Gave a talk at my parents’ retirement community to describe how science is done, and what is at stake. There was a ton of interest, and anyone can do this. Get the word out about how science affects everyone. I’m happy to share slides with anyone who asks- just get in touch! youtu.be/BY_SFgi-Cig
Kara Marshall PHD-History of Science in America - Trilogy at Tehaleh 04/27/25
YouTube video by Steve Lawson
youtu.be
May 3, 2025 at 7:20 PM
Gave a talk at my parents’ retirement community to describe how science is done, and what is at stake. There was a ton of interest, and anyone can do this. Get the word out about how science affects everyone. I’m happy to share slides with anyone who asks- just get in touch! youtu.be/BY_SFgi-Cig
Reposted by Ranier Gutierrez
The new Rutgers Center for NeuroMetabolism is officially hiring faculty at all levels! Come be my colleague!
jobs.rutgers.edu/postings/248...
jobs.rutgers.edu/postings/248...
Assistant/Associate/Full Professor
The newly launched Rutgers Center for NeuroMetabolism (CNM), in collaboration with the Child Health Institute of New Jersey (CHINJ), the Department of Neuroscience and Cell Biology (NCB), and the Rutg...
jobs.rutgers.edu
April 12, 2025 at 4:21 PM
The new Rutgers Center for NeuroMetabolism is officially hiring faculty at all levels! Come be my colleague!
jobs.rutgers.edu/postings/248...
jobs.rutgers.edu/postings/248...
New preprint from the lab, here we study head waving stereotypy induced by some appetite suppressants
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Sex-specific effects of appetite suppressants and stereotypy in rats
This study investigated the sex-specific effects of commonly prescribed appetite suppressants on body weight and the manifestation of motor side effects, specifically stereotypy. Employing video recor...
www.biorxiv.org
February 14, 2025 at 5:50 PM
New preprint from the lab, here we study head waving stereotypy induced by some appetite suppressants
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
New paper from the lab!!!
D2-expressing neurons in accumbens is rewarding but paradoxically it stops licking!
journals.plos.org/plosone/arti...
D2-expressing neurons in accumbens is rewarding but paradoxically it stops licking!
journals.plos.org/plosone/arti...
Nucleus accumbens D2-expressing neurons: Balancing reward and licking disruption through rhythmic optogenetic stimulation
Nucleus accumbens (NAc) dopamine D1 receptor-expressing neurons are known to be critical for processing reward and regulating food intake. However, the role of D2-expressing neurons in this nucleus re...
journals.plos.org
February 7, 2025 at 7:50 PM
New paper from the lab!!!
D2-expressing neurons in accumbens is rewarding but paradoxically it stops licking!
journals.plos.org/plosone/arti...
D2-expressing neurons in accumbens is rewarding but paradoxically it stops licking!
journals.plos.org/plosone/arti...
Reposted by Ranier Gutierrez
What if… spontaneous neural activity 🧠 reflects the baseline rumblings of a brainwide dynamical system initialized for learning? We find that the rumblings have macroscopic properties like those emerging from linear symmetric, critical systems 🧵 #neuroscience #neuroAI www.biorxiv.org/content/10.1...
January 12, 2025 at 7:55 PM
What if… spontaneous neural activity 🧠 reflects the baseline rumblings of a brainwide dynamical system initialized for learning? We find that the rumblings have macroscopic properties like those emerging from linear symmetric, critical systems 🧵 #neuroscience #neuroAI www.biorxiv.org/content/10.1...
Reposted by Ranier Gutierrez
GLP-1 receptor agonists (GLP-1RAs) are transforming the treatment of obesity and diabetes (and more). Our recent pre-print examined next-gen small molecules mimicking GLP-1, using humanized mouse models to uncover how they interact with brain circuits driving food consumption. 1/15
December 18, 2024 at 5:39 PM
GLP-1 receptor agonists (GLP-1RAs) are transforming the treatment of obesity and diabetes (and more). Our recent pre-print examined next-gen small molecules mimicking GLP-1, using humanized mouse models to uncover how they interact with brain circuits driving food consumption. 1/15
Reposted by Ranier Gutierrez
New work stemming from an amazing collaboration with @addisonwebster0 and @AUGCsoup using a combination of rabies mapping and single cell sequencing to identify a GLP1R-expressing local input to AgRP cells that curbs appetite rdcu.be/d2gB5
Molecular connectomics reveals a glucagon-like peptide 1-sensitive neural circuit for satiety
Nature Metabolism - Combining rabies-based connectomics with single-nucleus transcriptomics, the authors identify a neural circuit through which GLP-1 receptor agonists suppress appetite in mice.
rdcu.be
December 3, 2024 at 1:40 PM
New work stemming from an amazing collaboration with @addisonwebster0 and @AUGCsoup using a combination of rabies mapping and single cell sequencing to identify a GLP1R-expressing local input to AgRP cells that curbs appetite rdcu.be/d2gB5
Reposted by Ranier Gutierrez
A little late for Thanksgiving but if you have friends and family members curious about anti-obesity medications, this is very easy to digest piece (nailed that pun....still got it) authors.elsevier.com/a/1kCED3QW8S...
authors.elsevier.com
December 2, 2024 at 4:51 PM
A little late for Thanksgiving but if you have friends and family members curious about anti-obesity medications, this is very easy to digest piece (nailed that pun....still got it) authors.elsevier.com/a/1kCED3QW8S...
Reposted by Ranier Gutierrez
Order matters: neurons in the human brain fire in sequences that encode information www.nature.com/articles/d41...
Order matters: neurons in the human brain fire in sequences that encode information
A timing-based code for semantic knowledge in humans complements the established role of firing rates in neural coding.
www.nature.com
November 28, 2024 at 4:26 PM
Order matters: neurons in the human brain fire in sequences that encode information www.nature.com/articles/d41...
🧪🧠
Neuronal sequences are also present on gustatory cortices www.cell.com/iscience/ful...
Neuronal Sequences and dynamic coding of water-sucrose categorization in rat gustatory cortices
Neuroscience; Sensory neuroscience
www.cell.com
November 27, 2024 at 1:13 PM
🧪🧠
Optoception from a biohybrid graft. Really cool!!!
Optogenetic stimulation of a cortical biohybrid implant guides goal directed behavior https://www.biorxiv.org/content/10.1101/2024.11.22.624907v1
Optogenetic stimulation of a cortical biohybrid implant guides goal directed behavior https://www.biorxiv.org/content/10.1101/2024.11.22.624907v1
Brain-computer interfaces (BCIs) hold exciting therapeutic potential, but tissue damage caused by pr
www.biorxiv.org
November 24, 2024 at 1:28 PM
Optoception from a biohybrid graft. Really cool!!!
Neuronal ensembles in accumbens act as independent modules to process sucrose reward www.cell.com/cell-reports...
The flow of reward information through neuronal ensembles in the accumbens
Arroyo et al. show that NAcSh neuronal ensembles are distinct modules, each processing
specific aspects of reward-guided behavior. These ensembles adapt during learning,
forming different functional c...
www.cell.com
November 22, 2024 at 10:40 PM
Neuronal ensembles in accumbens act as independent modules to process sucrose reward www.cell.com/cell-reports...
Neuronal sequences are also present on gustatory cortices www.cell.com/iscience/ful...
Neuronal Sequences and dynamic coding of water-sucrose categorization in rat gustatory cortices
Neuroscience; Sensory neuroscience
www.cell.com
November 22, 2024 at 10:36 PM
Neuronal sequences are also present on gustatory cortices www.cell.com/iscience/ful...