Rajan Singh
@rajansingh.bsky.social
Asst Prof (R) #unrmed 🇺🇸 #DGBIs #Microbiome
#Gut-Brain-Microbiome #NeuroGastro #DGBIs #MetabolicHealth
#SoMe ✍️ #NGMJournal #INMAssociation #GutBrainScience
Alumnus #Gastro #SGPGIMS 🇮🇳
https://scholar.google.com/citations?hl=en&user=TBjcHp8AAAAJ
#Gut-Brain-Microbiome #NeuroGastro #DGBIs #MetabolicHealth
#SoMe ✍️ #NGMJournal #INMAssociation #GutBrainScience
Alumnus #Gastro #SGPGIMS 🇮🇳
https://scholar.google.com/citations?hl=en&user=TBjcHp8AAAAJ
Pinned
Rajan Singh
@rajansingh.bsky.social
· Nov 23
Reposted by Rajan Singh
New online! Gut–brain communication: types of sensory nerves and mechanisms of activation
Gut–brain communication: types of sensory nerves and mechanisms of activation
Nature Reviews Gastroenterology & Hepatology, Published online: 28 October 2025; doi:10.1038/s41575-025-01132-1This Review explores the different types of sensory nerves involved in gut–brain communication, detailing the locations of these nerve endings in the gut and their mechanisms of activation. Insights and new information regarding spinal and vagal afferents alongside viscerofugal neurons are detailed.
www.nature.com
October 28, 2025 at 12:28 PM
New online! Gut–brain communication: types of sensory nerves and mechanisms of activation
Reposted by Rajan Singh
ICYMI: New online! Proteases in intestinal health and disease
Proteases in intestinal health and disease
Nature Reviews Gastroenterology & Hepatology, Published online: 20 October 2025; doi:10.1038/s41575-025-01129-wIn this Review, Deraison and Vergnolle describe the role of extracellular proteases and protease inhibitors in gastrointestinal physiology and in diseases including inflammatory bowel disease, irritable bowel syndrome and colorectal cancer. They also explore emerging therapeutic options for restoring proteolytic balance.
www.nature.com
October 21, 2025 at 4:31 PM
ICYMI: New online! Proteases in intestinal health and disease
Reposted by Rajan Singh
ICYMI: New online! A neurobiotic sense curbs feeding: a new frontier in gut–brain communication
A neurobiotic sense curbs feeding: a new frontier in gut–brain communication
Nature Reviews Gastroenterology & Hepatology, Published online: 02 October 2025; doi:10.1038/s41575-025-01126-zIn a new study by Liu and colleagues, researchers demonstrated a novel neuroepithelial circuit in colonic neuropod cells through which a molecular pattern from resident microorganisms was relayed to the brain — a ‘neurobiotic sense’ by which the host adjusted its feeding behaviour by monitoring a gut microbial pattern.
www.nature.com
October 8, 2025 at 1:33 PM
ICYMI: New online! A neurobiotic sense curbs feeding: a new frontier in gut–brain communication
Reposted by Rajan Singh
New online! A neurobiotic sense curbs feeding: a new frontier in gut–brain communication
A neurobiotic sense curbs feeding: a new frontier in gut–brain communication
Nature Reviews Gastroenterology & Hepatology, Published online: 02 October 2025; doi:10.1038/s41575-025-01126-zIn a new study by Liu and colleagues, researchers demonstrated a novel neuroepithelial circuit in colonic neuropod cells through which a molecular pattern from resident microorganisms was relayed to the brain — a ‘neurobiotic sense’ by which the host adjusted its feeding behaviour by monitoring a gut microbial pattern.
www.nature.com
October 2, 2025 at 1:31 PM
New online! A neurobiotic sense curbs feeding: a new frontier in gut–brain communication
🆕🔥The Path Forward: Assessing a Pilot Competency-Based Curriculum on #DGBIs for Gastroenterology Trainees‼️ #NGMJournal
👉 onlinelibrary.wiley.com/doi/10.1111/nm…
✅DGBI education curriculum
✅Pre-&Post-individual knowledge scores
🎯Attitudes in managing DGBIs#ANMSocietyt#ESNMNM
June 12, 2025 at 4:14 PM
🆕🔥The Path Forward: Assessing a Pilot Competency-Based Curriculum on #DGBIs for Gastroenterology Trainees‼️ #NGMJournal
👉 onlinelibrary.wiley.com/doi/10.1111/nm…
✅DGBI education curriculum
✅Pre-&Post-individual knowledge scores
🎯Attitudes in managing DGBIs#ANMSocietyt#ESNMNM
Reposted by Rajan Singh
We are excited to announce the launch of our new podcast highlighting the latest in Gastropsych research. Our first episode features an interview with Dr. Sarah Ballou.
June 2, 2025 at 9:42 PM
We are excited to announce the launch of our new podcast highlighting the latest in Gastropsych research. Our first episode features an interview with Dr. Sarah Ballou.
Reposted by Rajan Singh
Find us on Spotify spotifycreators-web.app.link/e/e5BnWaqDPTb
Rome GastroPsych Podcast with Dr. Sarah Ballou by Rome_GastroPsych_Podcast
Our today's guest is Dr. Sarah Ballou, Clinical health Psychologist & director of the GI Behavioral Health Service at Beth Israel Deaconess Medical Center in Boston,Massachusetts. We discussed her gro...
spotifycreators-web.app.link
June 2, 2025 at 9:42 PM
Find us on Spotify spotifycreators-web.app.link/e/e5BnWaqDPTb
Reposted by Rajan Singh
Gene editing treatment helps desperately ill baby thrive. This brings real hope for countless others.
A win for US investment in science.
www.nytimes.com/2025/05/15/h...
A win for US investment in science.
www.nytimes.com/2025/05/15/h...
Baby Is Healed With World’s First Personalized Gene-Editing Treatment
www.nytimes.com
May 16, 2025 at 12:30 PM
Gene editing treatment helps desperately ill baby thrive. This brings real hope for countless others.
A win for US investment in science.
www.nytimes.com/2025/05/15/h...
A win for US investment in science.
www.nytimes.com/2025/05/15/h...
Reposted by Rajan Singh
Ever noticed your crying baby quiets when you carry them? It’s an evolutionary response.
Both infants and mice pups reduced crying, and lower heart rate when carried compared to being held while sitting.
.
Both infants and mice pups reduced crying, and lower heart rate when carried compared to being held while sitting.
.
May 18, 2025 at 3:44 PM
Ever noticed your crying baby quiets when you carry them? It’s an evolutionary response.
Both infants and mice pups reduced crying, and lower heart rate when carried compared to being held while sitting.
.
Both infants and mice pups reduced crying, and lower heart rate when carried compared to being held while sitting.
.
🆕🔥#NeuroGastroMotil
#Sex-specific alterations in intestinal neuronal-epithelial interactions between #CGRP & #Goblet cells secondary to elevated enteric #AlphaSynuclein potentially contribute to GI dysfunction in #Parkinson's Disease‼️
👉
onlinelibrary.wiley.com/doi/10.1111/nm…#ANMSocietyt#ESNMNM
#Sex-specific alterations in intestinal neuronal-epithelial interactions between #CGRP & #Goblet cells secondary to elevated enteric #AlphaSynuclein potentially contribute to GI dysfunction in #Parkinson's Disease‼️
👉
onlinelibrary.wiley.com/doi/10.1111/nm…#ANMSocietyt#ESNMNM
May 26, 2025 at 2:14 AM
🆕🔥#NeuroGastroMotil
#Sex-specific alterations in intestinal neuronal-epithelial interactions between #CGRP & #Goblet cells secondary to elevated enteric #AlphaSynuclein potentially contribute to GI dysfunction in #Parkinson's Disease‼️
👉
onlinelibrary.wiley.com/doi/10.1111/nm…#ANMSocietyt#ESNMNM
#Sex-specific alterations in intestinal neuronal-epithelial interactions between #CGRP & #Goblet cells secondary to elevated enteric #AlphaSynuclein potentially contribute to GI dysfunction in #Parkinson's Disease‼️
👉
onlinelibrary.wiley.com/doi/10.1111/nm…#ANMSocietyt#ESNMNM
Reposted by Rajan Singh
A must-listen for anyone working with people with DGBI 👇🏼 Great summary and experience from Alex Ford podcasts.apple.com/au/podcast/t...
#04: Professor Alex Ford - Navigating disorders of gut-brain interaction and IBS
Podcast Episode · Two guys talking **it - A Gastroenterology and Hepatology podcast · 22/01/2025 · 1h 11m
podcasts.apple.com
March 24, 2025 at 6:17 PM
A must-listen for anyone working with people with DGBI 👇🏼 Great summary and experience from Alex Ford podcasts.apple.com/au/podcast/t...
Reposted by Rajan Singh
And the prize for best title in GI goes to:
Love Thy Neighbor: Exploring Gastroenterology Attitudes toward Endometriosis Screening
@drlauriekeefer.bsky.social
@drmadisonsimons@bsky.social
pubmed.ncbi.nlm.nih.gov/39570538/
Love Thy Neighbor: Exploring Gastroenterology Attitudes toward Endometriosis Screening
@drlauriekeefer.bsky.social
@drmadisonsimons@bsky.social
pubmed.ncbi.nlm.nih.gov/39570538/
Love Thy Neighbor? Exploring Gastroenterology Attitudes Toward Endometriosis Screening - PubMed
Endometriosis is a chronic painful condition affecting 10% of reproductive-aged women with a high prevalence of overlapping gastrointestinal symptoms. There is a significant diagnostic delay for endom...
pubmed.ncbi.nlm.nih.gov
March 19, 2025 at 12:57 PM
And the prize for best title in GI goes to:
Love Thy Neighbor: Exploring Gastroenterology Attitudes toward Endometriosis Screening
@drlauriekeefer.bsky.social
@drmadisonsimons@bsky.social
pubmed.ncbi.nlm.nih.gov/39570538/
Love Thy Neighbor: Exploring Gastroenterology Attitudes toward Endometriosis Screening
@drlauriekeefer.bsky.social
@drmadisonsimons@bsky.social
pubmed.ncbi.nlm.nih.gov/39570538/
Reposted by Rajan Singh
⏳ How to Break Bedtime Procrastination
📵 Limit blue light
⏰ Set a “wind-down” alarm → A cue to start relaxing.
🎧 Swap scrolling for audio → Podcasts or music help detach.
🌿 Consider melatonin
🔁 Stick to a schedule → Consistent bed & wake times regulate your body clock.
📵 Limit blue light
⏰ Set a “wind-down” alarm → A cue to start relaxing.
🎧 Swap scrolling for audio → Podcasts or music help detach.
🌿 Consider melatonin
🔁 Stick to a schedule → Consistent bed & wake times regulate your body clock.
There are some great tips to help fight bedtime procrastination here.
💤 ADHD & Revenge Bedtime Procrastination: Take Back Your Nights! 🌙 open.substack.com/pub/adhdwisd...
#adhd #adhdawareness #adhdbedtimerevengeprocrastination
#adhdprocrastination
#adhd #adhdawareness #adhdbedtimerevengeprocrastination
#adhdprocrastination
February 24, 2025 at 12:19 PM
⏳ How to Break Bedtime Procrastination
📵 Limit blue light
⏰ Set a “wind-down” alarm → A cue to start relaxing.
🎧 Swap scrolling for audio → Podcasts or music help detach.
🌿 Consider melatonin
🔁 Stick to a schedule → Consistent bed & wake times regulate your body clock.
📵 Limit blue light
⏰ Set a “wind-down” alarm → A cue to start relaxing.
🎧 Swap scrolling for audio → Podcasts or music help detach.
🌿 Consider melatonin
🔁 Stick to a schedule → Consistent bed & wake times regulate your body clock.
Reposted by Rajan Singh
5 things I did this week to contribute to society:
1. Staid home when sick to protect others
2. Random acts of kindness as they tend to multiply
3. Recycled, to protect this earth
4. Donate/volunteer to give back to others
5. Shared evidence based health information to counteract misinformation
1. Staid home when sick to protect others
2. Random acts of kindness as they tend to multiply
3. Recycled, to protect this earth
4. Donate/volunteer to give back to others
5. Shared evidence based health information to counteract misinformation
February 24, 2025 at 3:31 PM
5 things I did this week to contribute to society:
1. Staid home when sick to protect others
2. Random acts of kindness as they tend to multiply
3. Recycled, to protect this earth
4. Donate/volunteer to give back to others
5. Shared evidence based health information to counteract misinformation
1. Staid home when sick to protect others
2. Random acts of kindness as they tend to multiply
3. Recycled, to protect this earth
4. Donate/volunteer to give back to others
5. Shared evidence based health information to counteract misinformation
🚨The Red Section: How I Approach it
✅The Management of #Gastroparesis Symptoms‼️
@amcollegegastro.bsky.social 🆕🔥
🎯Practical approaches to managing gastroparesis👏
✳️Choice of therapy in gastroparesis based on possible #pathophysiolocal correlates
✳️Dietary management👏
👉
journals.lww.com/ajg/citation...
✅The Management of #Gastroparesis Symptoms‼️
@amcollegegastro.bsky.social 🆕🔥
🎯Practical approaches to managing gastroparesis👏
✳️Choice of therapy in gastroparesis based on possible #pathophysiolocal correlates
✳️Dietary management👏
👉
journals.lww.com/ajg/citation...
February 4, 2025 at 2:08 PM
🚨The Red Section: How I Approach it
✅The Management of #Gastroparesis Symptoms‼️
@amcollegegastro.bsky.social 🆕🔥
🎯Practical approaches to managing gastroparesis👏
✳️Choice of therapy in gastroparesis based on possible #pathophysiolocal correlates
✳️Dietary management👏
👉
journals.lww.com/ajg/citation...
✅The Management of #Gastroparesis Symptoms‼️
@amcollegegastro.bsky.social 🆕🔥
🎯Practical approaches to managing gastroparesis👏
✳️Choice of therapy in gastroparesis based on possible #pathophysiolocal correlates
✳️Dietary management👏
👉
journals.lww.com/ajg/citation...
🆕🔥Yoga, Meditation, Mindfulness, or Hypnotherapy for GI disorders: Similar Mechanisms of Action?
🎯Evidence is building for mind body medicine in gut diseases‼️ @drvantilburg.bsky.social
✅Yoga, meditation & hypnotherapy may be beneficial for GI disorders👏
👉 onlinelibrary.wiley.com/doi/full/10....
🎯Evidence is building for mind body medicine in gut diseases‼️ @drvantilburg.bsky.social
✅Yoga, meditation & hypnotherapy may be beneficial for GI disorders👏
👉 onlinelibrary.wiley.com/doi/full/10....
February 4, 2025 at 1:53 PM
🆕🔥Yoga, Meditation, Mindfulness, or Hypnotherapy for GI disorders: Similar Mechanisms of Action?
🎯Evidence is building for mind body medicine in gut diseases‼️ @drvantilburg.bsky.social
✅Yoga, meditation & hypnotherapy may be beneficial for GI disorders👏
👉 onlinelibrary.wiley.com/doi/full/10....
🎯Evidence is building for mind body medicine in gut diseases‼️ @drvantilburg.bsky.social
✅Yoga, meditation & hypnotherapy may be beneficial for GI disorders👏
👉 onlinelibrary.wiley.com/doi/full/10....
Reposted by Rajan Singh
Thank you @rajansingh.bsky.social and all the faculty and grad students at @unevadareno.bsky.social who invited me to give a talk, and for many memorable meetings and chats!!
See who is here today #UNRMed
Dr. Subhash Kulkarni @klab.bsky.social 🙏
What an amazing talk on Age-associated gut dysmotility-linking development to aging👏
🎯ENS plasticity-Replacing the ENS through neurogenesis
So much learning in the field😇
Thanks a bunch for sharing ENS insights #Halloween mouse🔥
Dr. Subhash Kulkarni @klab.bsky.social 🙏
What an amazing talk on Age-associated gut dysmotility-linking development to aging👏
🎯ENS plasticity-Replacing the ENS through neurogenesis
So much learning in the field😇
Thanks a bunch for sharing ENS insights #Halloween mouse🔥
January 31, 2025 at 9:08 PM
Thank you @rajansingh.bsky.social and all the faculty and grad students at @unevadareno.bsky.social who invited me to give a talk, and for many memorable meetings and chats!!
See who is here today #UNRMed
Dr. Subhash Kulkarni @klab.bsky.social 🙏
What an amazing talk on Age-associated gut dysmotility-linking development to aging👏
🎯ENS plasticity-Replacing the ENS through neurogenesis
So much learning in the field😇
Thanks a bunch for sharing ENS insights #Halloween mouse🔥
Dr. Subhash Kulkarni @klab.bsky.social 🙏
What an amazing talk on Age-associated gut dysmotility-linking development to aging👏
🎯ENS plasticity-Replacing the ENS through neurogenesis
So much learning in the field😇
Thanks a bunch for sharing ENS insights #Halloween mouse🔥
January 31, 2025 at 6:03 AM
See who is here today #UNRMed
Dr. Subhash Kulkarni @klab.bsky.social 🙏
What an amazing talk on Age-associated gut dysmotility-linking development to aging👏
🎯ENS plasticity-Replacing the ENS through neurogenesis
So much learning in the field😇
Thanks a bunch for sharing ENS insights #Halloween mouse🔥
Dr. Subhash Kulkarni @klab.bsky.social 🙏
What an amazing talk on Age-associated gut dysmotility-linking development to aging👏
🎯ENS plasticity-Replacing the ENS through neurogenesis
So much learning in the field😇
Thanks a bunch for sharing ENS insights #Halloween mouse🔥
Reposted by Rajan Singh
Excited share that our @romefoundation.bsky.social Working Team's manuscript 📄 on Overlap in Disorders of Gut-Brain Interaction #DGBI is now published in @natrevgastrohep.bsky.social! Grateful for this amazing journey with global experts. Read here: nature.com/articles/s41...
#DGBI #GISky #GutSky
#DGBI #GISky #GutSky
January 27, 2025 at 2:47 PM
Excited share that our @romefoundation.bsky.social Working Team's manuscript 📄 on Overlap in Disorders of Gut-Brain Interaction #DGBI is now published in @natrevgastrohep.bsky.social! Grateful for this amazing journey with global experts. Read here: nature.com/articles/s41...
#DGBI #GISky #GutSky
#DGBI #GISky #GutSky
Reposted by Rajan Singh
🌟 Recognizing #DGBI in patients with organic GI disease remission prevents overtreatment with risky drugs and ensures targeted care. Let’s focus on better outcomes! 👉 bit.ly/3Ee3iwv #GISky #MedSky #GutSky
January 28, 2025 at 7:41 AM
🌟 Recognizing #DGBI in patients with organic GI disease remission prevents overtreatment with risky drugs and ensures targeted care. Let’s focus on better outcomes! 👉 bit.ly/3Ee3iwv #GISky #MedSky #GutSky
Reposted by Rajan Singh
Honoured but a bit sad to be giving the Inaugural Gary Mawe Memorial Lecture in @uvmvermont.bsky.social tomorrow. It will be strange to be in Vermont without Gary… a giant if Neurogastroenterology gone far too soon…
January 30, 2025 at 1:11 PM
Honoured but a bit sad to be giving the Inaugural Gary Mawe Memorial Lecture in @uvmvermont.bsky.social tomorrow. It will be strange to be in Vermont without Gary… a giant if Neurogastroenterology gone far too soon…
Reposted by Rajan Singh
Have a kid with a sweet tooth? It may be their gut microbiota steering their cravings.
How our gut microbiome regulates sugar preference nature.com/articles/s41...
January 24, 2025 at 10:39 PM
Have a kid with a sweet tooth? It may be their gut microbiota steering their cravings.
Reposted by Rajan Singh
A recent study found a complex, bidirectional relationship between marital quality and #DGBI symptoms in married Malay women. These findings underscore the importance of considering psychosocial factors when treating women with DGBIs.
January 24, 2025 at 4:20 PM
A recent study found a complex, bidirectional relationship between marital quality and #DGBI symptoms in married Malay women. These findings underscore the importance of considering psychosocial factors when treating women with DGBIs.
Reposted by Rajan Singh
Long #COVID symptoms persists for at least 2 years, study finds. Not great news for many sufferers.
journals.plos.org/plosmedicine...
journals.plos.org/plosmedicine...
Persistent symptoms and clinical findings in adults with post-acute sequelae of COVID-19/post-COVID-19 syndrome in the second year after acute infection: A population-based, nested case-control study
In a population-based case-control study, Raphael Peter and colleagues investigate the clinical characteristics and diagnostic findings in patients with post-COVID-19 syndrome.
journals.plos.org
January 24, 2025 at 10:45 PM
Long #COVID symptoms persists for at least 2 years, study finds. Not great news for many sufferers.
journals.plos.org/plosmedicine...
journals.plos.org/plosmedicine...
Reposted by Rajan Singh
I've been on Bluesky for a while now, waiting for a starter pack to bring the #DGBI community together. Since none existed, I decided to create one myself! The DGBI Starter Pack is here to help us connect, share, and grow together. Join us and make gut health a priority! 🌐🌱 #GISky #GutSky #IBS #FGID
January 24, 2025 at 10:15 PM
I've been on Bluesky for a while now, waiting for a starter pack to bring the #DGBI community together. Since none existed, I decided to create one myself! The DGBI Starter Pack is here to help us connect, share, and grow together. Join us and make gut health a priority! 🌐🌱 #GISky #GutSky #IBS #FGID