Quinn Sievers
@quinnsievers.bsky.social
Instructor in Lymphoma at Memorial Sloan Kettering and postdoc in the Abdel-Wahab and Vinogradova labs | Big problems, small molecules 🏳️🌈
Reposted by Quinn Sievers
The FDA is reversing a 2003 decision that put a stringent warning on hormone therapy products for menopausal women, saying that the treatments offer heart, brain, and bone health benefits. www.statnews.com/2025/11/10/f...
FDA reverses decades-old warning on hormone therapy products for menopause
The FDA is reversing a 2003 decision that put a stringent warning on hormone therapy products for menopausal women, saying that the treatments offer heart, brain, and bone health benefits.
www.statnews.com
November 10, 2025 at 4:02 PM
The FDA is reversing a 2003 decision that put a stringent warning on hormone therapy products for menopausal women, saying that the treatments offer heart, brain, and bone health benefits. www.statnews.com/2025/11/10/f...
Reposted by Quinn Sievers
biology is so cool because like every week someone is like "Dr. Smith is coming to campus! She is the world expert in blargyblarg!"
And i'm like A) never heard of blargyblarg, B) look it up, it's super important and interesting
And i'm like A) never heard of blargyblarg, B) look it up, it's super important and interesting
November 4, 2025 at 7:24 PM
biology is so cool because like every week someone is like "Dr. Smith is coming to campus! She is the world expert in blargyblarg!"
And i'm like A) never heard of blargyblarg, B) look it up, it's super important and interesting
And i'm like A) never heard of blargyblarg, B) look it up, it's super important and interesting
Reposted by Quinn Sievers
OMG.
Arena BioWorks, an ambitious biomedical institute backed by billionaires, abruptly shuts down www.statnews.com/2025/11/04/a... via @statnews.com
Arena BioWorks, an ambitious biomedical institute backed by billionaires, abruptly shuts down www.statnews.com/2025/11/04/a... via @statnews.com
Arena BioWorks, an ambitious biomedical institute backed by billionaires, abruptly shuts down
Exclusive: Arena Bioworks, the buzzy research institute that launched with $500 million to support a decade of scientific R&D, is abruptly shutting down, STAT has learned.
www.statnews.com
November 5, 2025 at 1:40 AM
OMG.
Arena BioWorks, an ambitious biomedical institute backed by billionaires, abruptly shuts down www.statnews.com/2025/11/04/a... via @statnews.com
Arena BioWorks, an ambitious biomedical institute backed by billionaires, abruptly shuts down www.statnews.com/2025/11/04/a... via @statnews.com
Reposted by Quinn Sievers
Finally out - our real world study of 740 patients with large B-cell lymphoma receiving polatuzumab vedotin shows higher response rates and PFS for patients with non-GCB LBCL than those with GCB disease, by Hans algorithm.
Thanks David Russler-Germain + collabs
aacrjournals.org/clincancerre...
Thanks David Russler-Germain + collabs
aacrjournals.org/clincancerre...
November 4, 2025 at 9:53 AM
Finally out - our real world study of 740 patients with large B-cell lymphoma receiving polatuzumab vedotin shows higher response rates and PFS for patients with non-GCB LBCL than those with GCB disease, by Hans algorithm.
Thanks David Russler-Germain + collabs
aacrjournals.org/clincancerre...
Thanks David Russler-Germain + collabs
aacrjournals.org/clincancerre...
Reposted by Quinn Sievers
A previously healthy man presented with a 10-day history of blood dripping from one nostril. Twenty days earlier, he had washed his face with mountain spring water. A leech was found on nasal endoscopy (shown in a video). Read the full case details: nej.md/3J6IZUD
#MedSky #Otolaryngology
#MedSky #Otolaryngology
November 3, 2025 at 8:16 PM
A previously healthy man presented with a 10-day history of blood dripping from one nostril. Twenty days earlier, he had washed his face with mountain spring water. A leech was found on nasal endoscopy (shown in a video). Read the full case details: nej.md/3J6IZUD
#MedSky #Otolaryngology
#MedSky #Otolaryngology
Reposted by Quinn Sievers
@nedlazaruswolfe.bsky.social and my book—Who Discovered How to Breathe Underwater?: Jacques Cousteau—comes out tomorrow!! 🤿🐟🌟
I plan to wake up, go vote in my local election, and maybe do an unboxing??
I plan to wake up, go vote in my local election, and maybe do an unboxing??
November 3, 2025 at 11:54 PM
@nedlazaruswolfe.bsky.social and my book—Who Discovered How to Breathe Underwater?: Jacques Cousteau—comes out tomorrow!! 🤿🐟🌟
I plan to wake up, go vote in my local election, and maybe do an unboxing??
I plan to wake up, go vote in my local election, and maybe do an unboxing??
Reposted by Quinn Sievers
seeing a lotta grant posts that want to me to solve problems using artificial intelligence
consider instead giving me a grant to use CAROLINE INTELLIGENCE
slower and dumber but MORE PUNS
consider instead giving me a grant to use CAROLINE INTELLIGENCE
slower and dumber but MORE PUNS
November 4, 2025 at 1:07 AM
seeing a lotta grant posts that want to me to solve problems using artificial intelligence
consider instead giving me a grant to use CAROLINE INTELLIGENCE
slower and dumber but MORE PUNS
consider instead giving me a grant to use CAROLINE INTELLIGENCE
slower and dumber but MORE PUNS
Reposted by Quinn Sievers
maslow's hierarchy of cells
1. physiological needs: oxygen, nutrients
2. safety: a tissue culture dish to adhere to
3. love and belonging: contact with surrounding cells
1. physiological needs: oxygen, nutrients
2. safety: a tissue culture dish to adhere to
3. love and belonging: contact with surrounding cells
November 2, 2025 at 12:20 AM
maslow's hierarchy of cells
1. physiological needs: oxygen, nutrients
2. safety: a tissue culture dish to adhere to
3. love and belonging: contact with surrounding cells
1. physiological needs: oxygen, nutrients
2. safety: a tissue culture dish to adhere to
3. love and belonging: contact with surrounding cells
Reposted by Quinn Sievers
science is a TEAM SPORT
there is no ISOLEUCINE in THREONINE GLUTAMATE ALANINE METHIONINE
there is no ISOLEUCINE in THREONINE GLUTAMATE ALANINE METHIONINE
October 31, 2025 at 6:58 PM
science is a TEAM SPORT
there is no ISOLEUCINE in THREONINE GLUTAMATE ALANINE METHIONINE
there is no ISOLEUCINE in THREONINE GLUTAMATE ALANINE METHIONINE
Reposted by Quinn Sievers
A 1-week-old full-term baby boy was brought back to the hospital with discharge from his navel. Physical examination showed pink tissue at the umbilicus that seeped yellow liquid. Abdominal ultrasonography was performed. What is the underlying pathophysiology? nej.md/IC10302025
#MedSky
#MedSky
October 31, 2025 at 7:02 PM
A 1-week-old full-term baby boy was brought back to the hospital with discharge from his navel. Physical examination showed pink tissue at the umbilicus that seeped yellow liquid. Abdominal ultrasonography was performed. What is the underlying pathophysiology? nej.md/IC10302025
#MedSky
#MedSky
Reposted by Quinn Sievers
In Brief: Vertex dives into covalent biologics with Enlaza Therapeutics in a multi-drug discovery collaboration worth up to $2 billion nature.com/articles/s41...
rdcu.be/eNF2U
rdcu.be/eNF2U
Vertex dives into covalent biologics - Nature Biotechnology
Nature Biotechnology - Vertex dives into covalent biologics
nature.com
October 31, 2025 at 3:40 PM
In Brief: Vertex dives into covalent biologics with Enlaza Therapeutics in a multi-drug discovery collaboration worth up to $2 billion nature.com/articles/s41...
rdcu.be/eNF2U
rdcu.be/eNF2U
Reposted by Quinn Sievers
Happy Halloween! 🎃🦇
Bats are more than just Halloween icons — HHMI scientists are studying them to explore fundamental questions about the brain & behavior. Their discoveries could have important implications for other species, including humans. Read more: bit.ly/434gm18
Bats are more than just Halloween icons — HHMI scientists are studying them to explore fundamental questions about the brain & behavior. Their discoveries could have important implications for other species, including humans. Read more: bit.ly/434gm18
October 31, 2025 at 3:50 PM
Happy Halloween! 🎃🦇
Bats are more than just Halloween icons — HHMI scientists are studying them to explore fundamental questions about the brain & behavior. Their discoveries could have important implications for other species, including humans. Read more: bit.ly/434gm18
Bats are more than just Halloween icons — HHMI scientists are studying them to explore fundamental questions about the brain & behavior. Their discoveries could have important implications for other species, including humans. Read more: bit.ly/434gm18
Reposted by Quinn Sievers
In untreated HER2-positive metastatic breast cancer, trastuzumab deruxtecan plus pertuzumab extended progression-free survival to 40.7 months, as compared with 26.9 months with THP, with a similar incidence of high-grade adverse events. Full DESTINY-Breast09 phase 3 trial results: nej.md/3JrVYjC
October 29, 2025 at 9:25 PM
In untreated HER2-positive metastatic breast cancer, trastuzumab deruxtecan plus pertuzumab extended progression-free survival to 40.7 months, as compared with 26.9 months with THP, with a similar incidence of high-grade adverse events. Full DESTINY-Breast09 phase 3 trial results: nej.md/3JrVYjC
Reposted by Quinn Sievers
At 23 years of follow-up, population-based PSA screening of asymptomatic men led to a sustained reduction in prostate cancer mortality, although overdiagnosis remains a concern. Full ERSPC study results: nej.md/42YYsg7
#MedSky #Oncology
#MedSky #Oncology
October 29, 2025 at 9:40 PM
At 23 years of follow-up, population-based PSA screening of asymptomatic men led to a sustained reduction in prostate cancer mortality, although overdiagnosis remains a concern. Full ERSPC study results: nej.md/42YYsg7
#MedSky #Oncology
#MedSky #Oncology
Reposted by Quinn Sievers
We are #hiring for a Tenure Track Assistant Professor position in the Department of Molecular&Cellular Physiology (med.stanford.edu/mcp.html) at @stanfordmedicine.bsky.social. Please apply or forward the opportunity to anybody who might be interested.
facultypositions.stanford.edu/en-us/job/49...
facultypositions.stanford.edu/en-us/job/49...
Stanford | Faculty Positions: Details - Assistant Professor of Molecular and Cellular Physiology
facultypositions.stanford.edu
October 29, 2025 at 5:13 PM
We are #hiring for a Tenure Track Assistant Professor position in the Department of Molecular&Cellular Physiology (med.stanford.edu/mcp.html) at @stanfordmedicine.bsky.social. Please apply or forward the opportunity to anybody who might be interested.
facultypositions.stanford.edu/en-us/job/49...
facultypositions.stanford.edu/en-us/job/49...
Reposted by Quinn Sievers
GIFT!
Study Finds mRNA Covid Vaccines Prolonged Life of Cancer Patients
By @markjohnpost.bsky.social
"Covid-19 vaccines, credited with saving millions of lives during the pandemic, set off a powerful alarm that rallies the human immune system against cancer and nearly doubles the median survival."
Study Finds mRNA Covid Vaccines Prolonged Life of Cancer Patients
By @markjohnpost.bsky.social
"Covid-19 vaccines, credited with saving millions of lives during the pandemic, set off a powerful alarm that rallies the human immune system against cancer and nearly doubles the median survival."
October 23, 2025 at 4:24 PM
GIFT!
Study Finds mRNA Covid Vaccines Prolonged Life of Cancer Patients
By @markjohnpost.bsky.social
"Covid-19 vaccines, credited with saving millions of lives during the pandemic, set off a powerful alarm that rallies the human immune system against cancer and nearly doubles the median survival."
Study Finds mRNA Covid Vaccines Prolonged Life of Cancer Patients
By @markjohnpost.bsky.social
"Covid-19 vaccines, credited with saving millions of lives during the pandemic, set off a powerful alarm that rallies the human immune system against cancer and nearly doubles the median survival."
Reposted by Quinn Sievers
Animals don't send emails.
Animals don't post rage bait on social media.
Vampire bats feed their friends.
Humpback whales make dinner together.
We can learn so much from animals.
Learn a new lesson from animals every month in the Love Notes from Nature 2026 calendar! Get one at squidfacts.net
Animals don't post rage bait on social media.
Vampire bats feed their friends.
Humpback whales make dinner together.
We can learn so much from animals.
Learn a new lesson from animals every month in the Love Notes from Nature 2026 calendar! Get one at squidfacts.net
October 27, 2025 at 4:05 PM
Animals don't send emails.
Animals don't post rage bait on social media.
Vampire bats feed their friends.
Humpback whales make dinner together.
We can learn so much from animals.
Learn a new lesson from animals every month in the Love Notes from Nature 2026 calendar! Get one at squidfacts.net
Animals don't post rage bait on social media.
Vampire bats feed their friends.
Humpback whales make dinner together.
We can learn so much from animals.
Learn a new lesson from animals every month in the Love Notes from Nature 2026 calendar! Get one at squidfacts.net
Reposted by Quinn Sievers
There's a new AI website called Formatmypaper.com promising to properly format citations for academic papers.
It might be useful (?) but I won't upload my original research randomly to AI websites I know nothing about.
Latest in the Lint Trap⬇️
linttrapofhistory.substack.com/p/brief-thou...
It might be useful (?) but I won't upload my original research randomly to AI websites I know nothing about.
Latest in the Lint Trap⬇️
linttrapofhistory.substack.com/p/brief-thou...
Brief Thoughts on New AI Affordances
Artificial Intelligence is starting to make inroads in two industries I know well: journalism and academia.
linttrapofhistory.substack.com
October 27, 2025 at 1:11 AM
There's a new AI website called Formatmypaper.com promising to properly format citations for academic papers.
It might be useful (?) but I won't upload my original research randomly to AI websites I know nothing about.
Latest in the Lint Trap⬇️
linttrapofhistory.substack.com/p/brief-thou...
It might be useful (?) but I won't upload my original research randomly to AI websites I know nothing about.
Latest in the Lint Trap⬇️
linttrapofhistory.substack.com/p/brief-thou...
Reposted by Quinn Sievers
A baby boy was transferred to a tertiary care hospital 5 days after birth. He had an intact manubrium but no corpus of the sternum, which had resulted in complete displacement of the heart outside the chest wall (shown in a video). Full case details: nej.md/4nh3USU
#MedSky #Neonatology #CardioSky
#MedSky #Neonatology #CardioSky
October 26, 2025 at 4:03 PM
A baby boy was transferred to a tertiary care hospital 5 days after birth. He had an intact manubrium but no corpus of the sternum, which had resulted in complete displacement of the heart outside the chest wall (shown in a video). Full case details: nej.md/4nh3USU
#MedSky #Neonatology #CardioSky
#MedSky #Neonatology #CardioSky
Reposted by Quinn Sievers
Our Images in Clinical Medicine section seeks striking, high-quality clinical images that illuminate the growing and evolving impact of climate change on human health for the second #EarthMonth feature to be published April 2026.
Learn more and submit your images: nej.md/event-info
Learn more and submit your images: nej.md/event-info
October 26, 2025 at 7:27 PM
Our Images in Clinical Medicine section seeks striking, high-quality clinical images that illuminate the growing and evolving impact of climate change on human health for the second #EarthMonth feature to be published April 2026.
Learn more and submit your images: nej.md/event-info
Learn more and submit your images: nej.md/event-info
Reposted by Quinn Sievers
Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it?
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
October 26, 2025 at 2:01 AM
Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it?
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪