Sam Foley
@physfoley.bsky.social
Physics of membranes and self-assembly || Biophysics postdoc at Johns Hopkins || Previously Penn State -> Carnegie Mellon || for I perplex others not because I am clear, but because I am utterly perplexed myself ||
www.samuelfoley.com
www.samuelfoley.com
Pinned
Sam Foley
@physfoley.bsky.social
· May 26
I’m excited to finally share our new preprint! Membrane-associated assembly processes like CME function as precisely-tunable, spatially targetable, robust on/off switches that don’t require energy at decision-time.
arxiv.org/abs/2505.17290
🧪
arxiv.org/abs/2505.17290
🧪
I know that the discourse around MDPI journals sort of dissipated over the past year, but over at the "International Journal of Molecular Sciences" (IF 4.9) there are still 230 special issues accepting submissions before end of year! I'm sure that's normal for reputable journals.
December 29, 2025 at 5:37 PM
I know that the discourse around MDPI journals sort of dissipated over the past year, but over at the "International Journal of Molecular Sciences" (IF 4.9) there are still 230 special issues accepting submissions before end of year! I'm sure that's normal for reputable journals.
Reposted by Sam Foley
Requested a correction from @princetonupress.bsky.social. Let's see what happens.
December 27, 2025 at 11:45 PM
Requested a correction from @princetonupress.bsky.social. Let's see what happens.
Reposted by Sam Foley
When the 🎄 hits your eye like a big pizza pie
December 28, 2025 at 2:28 AM
When the 🎄 hits your eye like a big pizza pie
When the 🎄 hits your eye like a big pizza pie
December 28, 2025 at 2:28 AM
When the 🎄 hits your eye like a big pizza pie
Reposted by Sam Foley
No one says to legit business owners, "hey I see there's an underground market selling toxic knock-offs of your product: how will you incorporate the toxic product AND protect your customers against its harms?" But apparently it's fine to make this suggestion to educators with respect to AI.
December 24, 2025 at 7:56 PM
No one says to legit business owners, "hey I see there's an underground market selling toxic knock-offs of your product: how will you incorporate the toxic product AND protect your customers against its harms?" But apparently it's fine to make this suggestion to educators with respect to AI.
Reposted by Sam Foley
Looking for a Christmas miracle for a kitty (aging parent situation) for Baltimore pals: (1/2)
""My mom can no longer keep Angelo (alas!!!) and we are looking to rehome him. Angelo is a total sweetheart. He is 6 years old, gentle, playful, friendly, and a lovebug."
""My mom can no longer keep Angelo (alas!!!) and we are looking to rehome him. Angelo is a total sweetheart. He is 6 years old, gentle, playful, friendly, and a lovebug."
December 25, 2025 at 2:07 PM
Looking for a Christmas miracle for a kitty (aging parent situation) for Baltimore pals: (1/2)
""My mom can no longer keep Angelo (alas!!!) and we are looking to rehome him. Angelo is a total sweetheart. He is 6 years old, gentle, playful, friendly, and a lovebug."
""My mom can no longer keep Angelo (alas!!!) and we are looking to rehome him. Angelo is a total sweetheart. He is 6 years old, gentle, playful, friendly, and a lovebug."
No matter how many times I see the Star Wars Holiday Special, I'm still not mentally prepared for the cooking show where a man in blackface plays a four-armed woman in a stereotypical 70's cooking show
December 25, 2025 at 3:00 AM
No matter how many times I see the Star Wars Holiday Special, I'm still not mentally prepared for the cooking show where a man in blackface plays a four-armed woman in a stereotypical 70's cooking show
Reposted by Sam Foley
a brief summary of what it’s like to be online in 2025
December 16, 2025 at 9:23 PM
a brief summary of what it’s like to be online in 2025
I love this
continuing a streak of comics for exclusively birders with the brilliant @willsantino.bsky.social
December 24, 2025 at 5:18 PM
I love this
Also true for cats
December 23, 2025 at 5:38 PM
Also true for cats
A good reminder that not only is mass surveillance increasing at an alarming rate in the US, it's often being done in extremely insecure ways that end up being a threat to public safety
www.youtube.com/watch?v=vU1-...
www.youtube.com/watch?v=vU1-...
This Flock Camera Leak is like Netflix For Stalkers
YouTube video by Benn Jordan
www.youtube.com
December 23, 2025 at 5:00 AM
A good reminder that not only is mass surveillance increasing at an alarming rate in the US, it's often being done in extremely insecure ways that end up being a threat to public safety
www.youtube.com/watch?v=vU1-...
www.youtube.com/watch?v=vU1-...
AI-controlled ships with nuclear armaments?
Well, at least we solved the Fermi paradox.
Well, at least we solved the Fermi paradox.
“Trump-class” Golden Fleet AI-controlled battleships will be the largest "in the history of the world ever built" with hypersonic weapons, the most-sophisticated lasers and Cruise nuclear missiles and "ultimately there'll be 20 to 25 of these," announces the president.
December 22, 2025 at 11:33 PM
AI-controlled ships with nuclear armaments?
Well, at least we solved the Fermi paradox.
Well, at least we solved the Fermi paradox.
Reposted by Sam Foley
My lab in the NIH Intramural Program (Bethesda, MD) will be recruiting postdoctoral fellows over the next year with flexible start dates. We work on nanoscale cellular imaging of the plasma membrane and related organelles. Please reach out if you’re interested. www.training.nih.gov/jobs/pdp-053...
December 22, 2025 at 2:57 PM
My lab in the NIH Intramural Program (Bethesda, MD) will be recruiting postdoctoral fellows over the next year with flexible start dates. We work on nanoscale cellular imaging of the plasma membrane and related organelles. Please reach out if you’re interested. www.training.nih.gov/jobs/pdp-053...
I already wasn't going to ever buy a "smart fridge", you don't have to convince me even more
Samsung Is Putting Google Gemini AI Into Your Refrigerator, Whether You Need It or Not
https://slashdot.org/story/25/12/22/120248/samsung-is-putting-google-gemini-ai-into-your-refrigerator-whether-you-need-it-or-not?utm_source=rss1.0mainlinkanon&utm_medium=feed
Samsung Is Putting Google Gemini AI Into Your Refrigerator, Whether You Need It or Not
BrianFagioli writes: Samsung is bringing Google Gemini directly into the kitchen, starting with a refrigerator that can see what you eat. At CES 2026, the company plans to show off a new Bespoke AI Refrigerator that uses a built in camera system paired with Gemini to automatically recognize food ite...
slashdot.org
December 22, 2025 at 4:22 PM
I already wasn't going to ever buy a "smart fridge", you don't have to convince me even more
Reposted by Sam Foley
Love this. The knowledge that I'm most proud to have created is a critique of "foundation models", including but not limited to LLMs, based on scientific and chemical ethics. This involved a grounded theory analysis of chemical codes of ethics to define what "chemical ethics" even are.
December 22, 2025 at 2:08 PM
Love this. The knowledge that I'm most proud to have created is a critique of "foundation models", including but not limited to LLMs, based on scientific and chemical ethics. This involved a grounded theory analysis of chemical codes of ethics to define what "chemical ethics" even are.
So the current administration now reviews and signs off on all potentially controversial CBS content prior to airing? lol
CBS News postponed a "60 Minutes" segment Sunday because it lacked a Trump admin interview, per an email we obtained from correspondent Sharyn Alfonsi, who said the decision by EIC Bari Weiss gave the White House a "kill switch." with @liamjscott.bsky.social
www.washingtonpost.com/business/202...
www.washingtonpost.com/business/202...
‘60 Minutes’ correspondent says CBS’s Bari Weiss abruptly pulled segment on Trump deportations
CBS News pulled a ‘60 Minutes’ segment about a prison in El Salvador one day before it was set to air because the Trump administration declined to participate.
www.washingtonpost.com
December 22, 2025 at 3:47 AM
So the current administration now reviews and signs off on all potentially controversial CBS content prior to airing? lol
Reposted by Sam Foley
This Yglesias piece in the NYT is horrifically bad. Almost every "fact" it cites is provably false. At best it is cocktail party banter from a pundit who knows nothing of energy. At worst, it was cut/paste from oil industry talking points. So, a rebuttal: www.nytimes.com/2025/12/18/o...
Opinion | Obama Supported It. The Left in Canada and Norway Does. Why Don’t Democrats?
www.nytimes.com
December 20, 2025 at 2:57 PM
This Yglesias piece in the NYT is horrifically bad. Almost every "fact" it cites is provably false. At best it is cocktail party banter from a pundit who knows nothing of energy. At worst, it was cut/paste from oil industry talking points. So, a rebuttal: www.nytimes.com/2025/12/18/o...
Reposted by Sam Foley
HAPPY HOLIDAYS TO ALL OF YOU!🎄✨
December 19, 2025 at 6:08 PM
HAPPY HOLIDAYS TO ALL OF YOU!🎄✨
Holiday mood:
December 18, 2025 at 3:57 PM
Holiday mood:
Reposted by Sam Foley
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1
December 17, 2025 at 12:46 AM
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Every day that goes by, I become more and more demoralized by the sheer amount of tech debt being accumulated through reliance on LLMs.
December 16, 2025 at 9:55 PM
Every day that goes by, I become more and more demoralized by the sheer amount of tech debt being accumulated through reliance on LLMs.
Just saw this plot in a colleague's simulation analysis output, and realized it pretty accurately describes my mental state as well
December 16, 2025 at 8:45 PM
Just saw this plot in a colleague's simulation analysis output, and realized it pretty accurately describes my mental state as well
Reposted by Sam Foley
Oh to be a little Tardigrade walking across a microscopic slide. 🫧🐻🧪
December 16, 2025 at 7:00 PM
Oh to be a little Tardigrade walking across a microscopic slide. 🫧🐻🧪
Reposted by Sam Foley
This entire weekend
December 15, 2025 at 3:58 AM
This entire weekend