Robin Conibere
@pharmrj.pharmsky.app
Lead PCN Pharmacist & Partner bmg.link/us
A believer in the benefits of #pharmacy and #pharmacists #Pharmsky
Views expressed are my own t.me/PharmRJ
rbnc.cc
A believer in the benefits of #pharmacy and #pharmacists #Pharmsky
Views expressed are my own t.me/PharmRJ
rbnc.cc
Reposted by Robin Conibere
Sorry @erictopol.bsky.social it doesn't. All participants were normal coffee drinkers. Therefore, the coffee-drinker arm is the Control arm. The intervention of going cold turkey increased the hazard of AF by 64% (100/0.61). The whole report is written from the wrong perspective.
November 10, 2025 at 12:02 AM
Sorry @erictopol.bsky.social it doesn't. All participants were normal coffee drinkers. Therefore, the coffee-drinker arm is the Control arm. The intervention of going cold turkey increased the hazard of AF by 64% (100/0.61). The whole report is written from the wrong perspective.
Reposted by Robin Conibere
🚨 Physician Alert: Urinary drugs increase risk of dementia
- Anticholinergic therapy was linked to a 28% increased risk compared to those who used mirabegron (a beta-3 agonist). Mirabegron may be a safer alternative for long-term management. Repost. 📰 htt*ps://buff.ly/lFHYCuJ
- Anticholinergic therapy was linked to a 28% increased risk compared to those who used mirabegron (a beta-3 agonist). Mirabegron may be a safer alternative for long-term management. Repost. 📰 htt*ps://buff.ly/lFHYCuJ
November 10, 2025 at 12:30 PM
🚨 Physician Alert: Urinary drugs increase risk of dementia
- Anticholinergic therapy was linked to a 28% increased risk compared to those who used mirabegron (a beta-3 agonist). Mirabegron may be a safer alternative for long-term management. Repost. 📰 htt*ps://buff.ly/lFHYCuJ
- Anticholinergic therapy was linked to a 28% increased risk compared to those who used mirabegron (a beta-3 agonist). Mirabegron may be a safer alternative for long-term management. Repost. 📰 htt*ps://buff.ly/lFHYCuJ
Reposted by Robin Conibere
I spoke to CNN about how demoralizing it was to watch Stanford leadership stay silent while contrarians on campus launched unscientific attacks to stifle Stanford researchers. Now, those attacks have gone nationwide and much of MAHA leadership have ties to Stanford.
www.cnn.com/2025/11/08/p...
www.cnn.com/2025/11/08/p...
The Trump-MAHA-Stanford nexus of US health policy | CNN Politics
In early 2022, Stanford medical student Santiago Sanchez set out to organize a campus debate with Jay Bhattacharya — a professor at the university whose outspoken denunciations of pandemic lockdowns m...
www.cnn.com
November 10, 2025 at 5:52 PM
I spoke to CNN about how demoralizing it was to watch Stanford leadership stay silent while contrarians on campus launched unscientific attacks to stifle Stanford researchers. Now, those attacks have gone nationwide and much of MAHA leadership have ties to Stanford.
www.cnn.com/2025/11/08/p...
www.cnn.com/2025/11/08/p...
Reposted by Robin Conibere
Get this: Coffee suppressed atrial fibrillation!
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
November 9, 2025 at 2:51 PM
Get this: Coffee suppressed atrial fibrillation!
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
Reposted by Robin Conibere
TUXEDO-2 findings suggest a ticagrelor-based #DAPT regimen does not offer the same level of benefit at preventing heart attack, stroke, bleeding complications or death as a prasugrel-based regimen.
Read more as part of our #AHA25 coverage: https://bit.ly/4p5NoXe #CardioSky #MedSky
Read more as part of our #AHA25 coverage: https://bit.ly/4p5NoXe #CardioSky #MedSky
November 10, 2025 at 3:10 PM
TUXEDO-2 findings suggest a ticagrelor-based #DAPT regimen does not offer the same level of benefit at preventing heart attack, stroke, bleeding complications or death as a prasugrel-based regimen.
Read more as part of our #AHA25 coverage: https://bit.ly/4p5NoXe #CardioSky #MedSky
Read more as part of our #AHA25 coverage: https://bit.ly/4p5NoXe #CardioSky #MedSky
Reposted by Robin Conibere
Oh yay..."flu jab SOS" from the NHS... go get yours y'all! www.bbc.co.uk/news/article...
November 10, 2025 at 9:58 PM
Oh yay..."flu jab SOS" from the NHS... go get yours y'all! www.bbc.co.uk/news/article...
Reposted by Robin Conibere
📢 POLY-HF: Daily Polypill Boosts Heart Function, QOL, and Cuts Hospitalizations in Underserved Patients With #HFrEF
Read more: https://bit.ly/4hV9byv
#AHA25 #HeartFailure #CardioSky #MedSky
Read more: https://bit.ly/4hV9byv
#AHA25 #HeartFailure #CardioSky #MedSky
November 10, 2025 at 10:35 PM
📢 POLY-HF: Daily Polypill Boosts Heart Function, QOL, and Cuts Hospitalizations in Underserved Patients With #HFrEF
Read more: https://bit.ly/4hV9byv
#AHA25 #HeartFailure #CardioSky #MedSky
Read more: https://bit.ly/4hV9byv
#AHA25 #HeartFailure #CardioSky #MedSky
Reposted by Robin Conibere
This learning article explores how to recognise opportunities for medicines optimisation and rationalisation during the course of the patient journey following a frailty-related hospital admission
#ukpharmacy #frailty
#ukpharmacy #frailty
Frailty and the patient journey
Frailty of old age and deprivation are two of the most common determinants influencing a patient’s likelihood to be admitted to A&E1. There is a recognised geographical correlation between advanced…
buff.ly
November 10, 2025 at 7:00 PM
This learning article explores how to recognise opportunities for medicines optimisation and rationalisation during the course of the patient journey following a frailty-related hospital admission
#ukpharmacy #frailty
#ukpharmacy #frailty
Saw this and thought of @medcrisis.bsky.social's attempts to dispel some of this bullshit over the years but I think things are just getting worse
November 10, 2025 at 1:17 PM
Saw this and thought of @medcrisis.bsky.social's attempts to dispel some of this bullshit over the years but I think things are just getting worse
Reposted by Robin Conibere
New BMJ Research: Existing evidence does not clearly link paracetamol (acetaminophen) use during pregnancy with autism or ADHD in children, finds an in-depth evidence review
www.bmj.com/content/391/...
www.bmj.com/content/391/...
November 10, 2025 at 10:07 AM
New BMJ Research: Existing evidence does not clearly link paracetamol (acetaminophen) use during pregnancy with autism or ADHD in children, finds an in-depth evidence review
www.bmj.com/content/391/...
www.bmj.com/content/391/...
Reposted by Robin Conibere
I had a lovely catch up chat with @jamesheathers.bsky.social at the weekend. I am thoroughly inspired by the work he and team are doing at the Medical Evidence Project. They act on tip offs for fraudulent and/or inaccurate science used to shape medical practice. Know any? medicalevidenceproject.org
The Medical Evidence Project
We find bad research that affects health and life
medicalevidenceproject.org
November 10, 2025 at 8:30 AM
I had a lovely catch up chat with @jamesheathers.bsky.social at the weekend. I am thoroughly inspired by the work he and team are doing at the Medical Evidence Project. They act on tip offs for fraudulent and/or inaccurate science used to shape medical practice. Know any? medicalevidenceproject.org
Reposted by Robin Conibere
A randomized clinical trial published in JAMA found that patients with AF who consumed caffeinated coffee had a lower risk of recurrent AF or atrial flutter compared with those who abstained.
#AHA25 #AFib @ahascience.bsky.social
ja.ma/43UFh7x
#AHA25 #AFib @ahascience.bsky.social
ja.ma/43UFh7x
November 9, 2025 at 5:00 PM
A randomized clinical trial published in JAMA found that patients with AF who consumed caffeinated coffee had a lower risk of recurrent AF or atrial flutter compared with those who abstained.
#AHA25 #AFib @ahascience.bsky.social
ja.ma/43UFh7x
#AHA25 #AFib @ahascience.bsky.social
ja.ma/43UFh7x
Reposted by Robin Conibere
Fascinating paper suggesting the assumption that there is a sigmoid dose response relationship and threshold effect ( "all-or-nothing") for loop diuretics rests on repeated misinterpretation of original studies from the 70s and 80s. #nephsky #cardiosky #emimcc academic.oup.com/ehjcvp/artic...
What are the pharmacodynamics of loop diuretics?
A recent editorial was entitled ‘Loop diuretics in heart failure: few facts and lots of prejudice’.1 I would argue that we have forgotten or distorted some
academic.oup.com
November 9, 2025 at 6:40 PM
Fascinating paper suggesting the assumption that there is a sigmoid dose response relationship and threshold effect ( "all-or-nothing") for loop diuretics rests on repeated misinterpretation of original studies from the 70s and 80s. #nephsky #cardiosky #emimcc academic.oup.com/ehjcvp/artic...
Reposted by Robin Conibere
No clear evidence to support any link between maternal acetaminophen (Tylenol) intake and autism or ADHD in offspring, a new umbrella, systematic review
@bmj.com
@bmj.com
November 10, 2025 at 12:19 AM
No clear evidence to support any link between maternal acetaminophen (Tylenol) intake and autism or ADHD in offspring, a new umbrella, systematic review
@bmj.com
@bmj.com
Reposted by Robin Conibere
I started a talk a few weeks ago by talking about how many of these otherwise healthy young men are ending up on my table with heart disease. The link is broadly anecdotal at the moment – no cardiovascular research exists with TRT in patients who DON’T have a pre existing proven deficiency
November 9, 2025 at 9:04 AM
I started a talk a few weeks ago by talking about how many of these otherwise healthy young men are ending up on my table with heart disease. The link is broadly anecdotal at the moment – no cardiovascular research exists with TRT in patients who DON’T have a pre existing proven deficiency
Reposted by Robin Conibere
iSIMPATHY: a multinational pre–post non-randomised intervention study transforming medication review
#Pharmsky
bmjopen.bmj.com/content/15/1...
#Pharmsky
bmjopen.bmj.com/content/15/1...
iSIMPATHY: a multinational pre–post non-randomised intervention study transforming medication review
Background Taking multiple medicines can be appropriate but has the potential to be problematic. The Implementing Stimulating Innovation in the Management of Polypharmacy and Adherence THrough the Yea...
bmjopen.bmj.com
November 9, 2025 at 8:32 AM
iSIMPATHY: a multinational pre–post non-randomised intervention study transforming medication review
#Pharmsky
bmjopen.bmj.com/content/15/1...
#Pharmsky
bmjopen.bmj.com/content/15/1...
Reposted by Robin Conibere
It’s really important that #Vancouver’s Downtown Business Association, who were originally against bike-lanes, are now among their most vigourous supporters, because of ACTUAL EVIDENCE that they’re better for downtown business than any street parking they replaced.
Safe bike-lanes mean business.
Safe bike-lanes mean business.
November 8, 2025 at 3:51 AM
It’s really important that #Vancouver’s Downtown Business Association, who were originally against bike-lanes, are now among their most vigourous supporters, because of ACTUAL EVIDENCE that they’re better for downtown business than any street parking they replaced.
Safe bike-lanes mean business.
Safe bike-lanes mean business.
Reposted by Robin Conibere
Functional medicine is grifty pseudoscientific horsemanure, an insult to evidence based preventative health/primary care medicine.
November 8, 2025 at 11:28 AM
Functional medicine is grifty pseudoscientific horsemanure, an insult to evidence based preventative health/primary care medicine.
Reposted by Robin Conibere
Against overmedicalization youtu.be/OQ7g1lQ26s0 @medcrisis.bsky.social
Screening Saves Lives! Right??
YouTube video by Medlife Crisis
youtu.be
November 9, 2025 at 6:20 AM
Against overmedicalization youtu.be/OQ7g1lQ26s0 @medcrisis.bsky.social
Reposted by Robin Conibere
In patients with atrial fibrillation after successful ablation, rivaroxaban therapy did not lead to a significantly lower incidence of a composite of stroke, systemic embolism, or new covert embolic stroke than aspirin therapy. Full OCEAN trial results: nej.md/3LsRJ86
#AHA25
#AHA25
November 8, 2025 at 8:20 PM
In patients with atrial fibrillation after successful ablation, rivaroxaban therapy did not lead to a significantly lower incidence of a composite of stroke, systemic embolism, or new covert embolic stroke than aspirin therapy. Full OCEAN trial results: nej.md/3LsRJ86
#AHA25
#AHA25
Reposted by Robin Conibere
jamanetwork.com/journals/jam...
The Rise in Early-Onset Cancer in the US Population - More Apparent Than Real
Epidemiology 101
All screening does harm, some screening does good etc
Here is a telling example of harm
And we wonder why there is a crisis in workload and workforce in cancer care
The Rise in Early-Onset Cancer in the US Population - More Apparent Than Real
Epidemiology 101
All screening does harm, some screening does good etc
Here is a telling example of harm
And we wonder why there is a crisis in workload and workforce in cancer care
November 8, 2025 at 9:36 AM
jamanetwork.com/journals/jam...
The Rise in Early-Onset Cancer in the US Population - More Apparent Than Real
Epidemiology 101
All screening does harm, some screening does good etc
Here is a telling example of harm
And we wonder why there is a crisis in workload and workforce in cancer care
The Rise in Early-Onset Cancer in the US Population - More Apparent Than Real
Epidemiology 101
All screening does harm, some screening does good etc
Here is a telling example of harm
And we wonder why there is a crisis in workload and workforce in cancer care
Reposted by Robin Conibere
Such a fab graph. A whole story re: waste of resources and needless anxiety in 3 lines.
November 8, 2025 at 12:38 PM
Such a fab graph. A whole story re: waste of resources and needless anxiety in 3 lines.
Reposted by Robin Conibere
Major imposter syndrome to be awarded the @rpharms.com Fellow today by @clairewynn.bsky.social President of RPS. #pharmacy #RPSConf25
November 7, 2025 at 10:30 PM
Major imposter syndrome to be awarded the @rpharms.com Fellow today by @clairewynn.bsky.social President of RPS. #pharmacy #RPSConf25
Reposted by Robin Conibere
👋🏻
James Watson, Who Helped Discover the Structure of DNA, Is Dead at 97
www.nytimes.com
November 7, 2025 at 7:32 PM
👋🏻
Reposted by Robin Conibere
I rarely interact with screening since in many sense both ICU and anaesthetics are tertiary specialties but the notion of "less is more" is one sometimes people struggle with but is frequently the right choice.
Great vid from Rohin.
Great vid from Rohin.
Trying to bring a bit of old fashioned classic twitter-era medical discussion to Bluesky!
Made a short video about the huge Prostate Cancer Screening study just published in @nejm.org. Regular media and social media docs have, predictably, made a hash of the results #medsky
youtu.be/OQ7g1lQ26s0?...
Made a short video about the huge Prostate Cancer Screening study just published in @nejm.org. Regular media and social media docs have, predictably, made a hash of the results #medsky
youtu.be/OQ7g1lQ26s0?...
Screening Saves Lives! Right??
YouTube video by Medlife Crisis
youtu.be
November 5, 2025 at 9:05 PM
I rarely interact with screening since in many sense both ICU and anaesthetics are tertiary specialties but the notion of "less is more" is one sometimes people struggle with but is frequently the right choice.
Great vid from Rohin.
Great vid from Rohin.