Pavithra Viswanath
@pavithraviswanath.bsky.social
Associate Professor of Radiology and Biomedical Imaging at UCSF. My research program is focused on leveraging cancer biology for metabolic imaging and therapy.
Reposted by Pavithra Viswanath
Reposted by Pavithra Viswanath
🥳 Our 5th most downloaded article in 2024:
Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment by Calvin Kuo, Polk & Elisa Zhang
https://bit.ly/4jAOu...
@stanfordpress.bsky.social @stanfordmedicine.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment by Calvin Kuo, Polk & Elisa Zhang
https://bit.ly/4jAOu...
@stanfordpress.bsky.social @stanfordmedicine.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment - Nature Reviews Cancer
In this Review, Polak, Zhang and Kuo discuss the currently available and rapidly evolving 3D tumour organoid models that capture the tumour immune microenvironment. They highlight opportunities for organoid-based investigations of tumour immunity, drug development and precision medicine.
bit.ly
February 10, 2025 at 2:00 PM
🥳 Our 5th most downloaded article in 2024:
Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment by Calvin Kuo, Polk & Elisa Zhang
https://bit.ly/4jAOu...
@stanfordpress.bsky.social @stanfordmedicine.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment by Calvin Kuo, Polk & Elisa Zhang
https://bit.ly/4jAOu...
@stanfordpress.bsky.social @stanfordmedicine.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Reposted by Pavithra Viswanath
Join us on March 13-14, 2025, for a special in-person postdoctoral recruitment event @winshipatemory.bsky.social. Network with mentors and postdocs in our Cancer Research programs, and explore our community and career resources. Apply by January 31, 2025. Details & Application: brnw.ch/21wPrWk
January 25, 2025 at 7:17 PM
Join us on March 13-14, 2025, for a special in-person postdoctoral recruitment event @winshipatemory.bsky.social. Network with mentors and postdocs in our Cancer Research programs, and explore our community and career resources. Apply by January 31, 2025. Details & Application: brnw.ch/21wPrWk
Reposted by Pavithra Viswanath
So important to mention this when talking to politicians or the public: $2.64 of economic activity for every $1 of NIH research funding!
“NIH produces an astounding return on investment to the American taxpayer. In Fiscal Year 2022, NIH research funding supported 568,585 jobs and generated $96.84 billion in economic activity — that’s $2.64 of economic activity for every $1 of research funding.”
www.researchamerica.org/2023-oped-us...
www.researchamerica.org/2023-oped-us...
Research supported by NIH has led more than 100 Nobel Prizes and has supported more than 99% of drugs approved by federal regulators from 2010 to 2019.
But come January, NIH may face a wrecking ball
nytimes.com/2024/12/01/h...
But come January, NIH may face a wrecking ball
nytimes.com/2024/12/01/h...
January 4, 2025 at 8:09 PM
So important to mention this when talking to politicians or the public: $2.64 of economic activity for every $1 of NIH research funding!
Reposted by Pavithra Viswanath
Lactylation fuels nucleotide biosynthesis and facilitates deuterium metabolic imaging of tumor proliferation in H3K27M-mutant gliomas https://www.biorxiv.org/content/10.1101/2025.01.02.631150v1
January 3, 2025 at 3:50 PM
Lactylation fuels nucleotide biosynthesis and facilitates deuterium metabolic imaging of tumor proliferation in H3K27M-mutant gliomas https://www.biorxiv.org/content/10.1101/2025.01.02.631150v1
First post on Bluesky- new preprint! We show that lactate drives NTP synthesis via lactylation of the nucleoside diphosphate kinase NME1 in pediatric gliomas. Deuterium metabolic imaging of lactate production interrogates tumor growth and therapy response in vivo. www.biorxiv.org/content/10.1...
Lactylation fuels nucleotide biosynthesis and facilitates deuterium metabolic imaging of tumor proliferation in H3K27M-mutant gliomas
Oncogenes hyperactive lactate production, but the mechanisms by which lactate facilitates tumor growth are unclear. Here, we demonstrate that lactate is essential for nucleotide biosynthesis in pediat...
www.biorxiv.org
January 3, 2025 at 4:11 PM
First post on Bluesky- new preprint! We show that lactate drives NTP synthesis via lactylation of the nucleoside diphosphate kinase NME1 in pediatric gliomas. Deuterium metabolic imaging of lactate production interrogates tumor growth and therapy response in vivo. www.biorxiv.org/content/10.1...