Irene Beusch
@pauletteoctopus.bsky.social
junior group leader at University of Würzburg || RNA biologist with a 🖤 for splicing || science & 🎨, #firstgen www.beuschlab.org
Reposted by Irene Beusch
@iubmb.bsky.social event on careers outside academia:
Dr Freskida Goni, Founder (Venture Capital and Consultancy)
Dr Daniele Mazzoletti, Scientific Project Manager (IXTAL Srl - Protein Intelligence)
Juliana Spahr, Science Illustrator
📅22/01/26 ⌚5 PM (CET)
us02web.zoom.us/webinar/regi...
Dr Freskida Goni, Founder (Venture Capital and Consultancy)
Dr Daniele Mazzoletti, Scientific Project Manager (IXTAL Srl - Protein Intelligence)
Juliana Spahr, Science Illustrator
📅22/01/26 ⌚5 PM (CET)
us02web.zoom.us/webinar/regi...
January 13, 2026 at 9:12 AM
@iubmb.bsky.social event on careers outside academia:
Dr Freskida Goni, Founder (Venture Capital and Consultancy)
Dr Daniele Mazzoletti, Scientific Project Manager (IXTAL Srl - Protein Intelligence)
Juliana Spahr, Science Illustrator
📅22/01/26 ⌚5 PM (CET)
us02web.zoom.us/webinar/regi...
Dr Freskida Goni, Founder (Venture Capital and Consultancy)
Dr Daniele Mazzoletti, Scientific Project Manager (IXTAL Srl - Protein Intelligence)
Juliana Spahr, Science Illustrator
📅22/01/26 ⌚5 PM (CET)
us02web.zoom.us/webinar/regi...
Reposted by Irene Beusch
Our first paper is out today in @natmicrobiol.nature.com!
We introduce a prostate organoid model and show that UPEC invades prostate cells via FimH binding to the prostate-specific protein PAPP. A step toward targeted therapies against bacterial prostatitis. 🎉
#UTI #UPEC #Organoids #AMR
We introduce a prostate organoid model and show that UPEC invades prostate cells via FimH binding to the prostate-specific protein PAPP. A step toward targeted therapies against bacterial prostatitis. 🎉
#UTI #UPEC #Organoids #AMR
Uropathogenic Escherichia coli invade luminal prostate cells via FimH–PPAP receptor binding - Nature Microbiology
Uropathogenic Escherichia coli infection of a murine prostate organoid model reveals a bacterial FimH–host prostatic acid phosphatase adhesin-receptor interaction enabling invasion and replication wit...
www.nature.com
January 8, 2026 at 11:12 AM
Our first paper is out today in @natmicrobiol.nature.com!
We introduce a prostate organoid model and show that UPEC invades prostate cells via FimH binding to the prostate-specific protein PAPP. A step toward targeted therapies against bacterial prostatitis. 🎉
#UTI #UPEC #Organoids #AMR
We introduce a prostate organoid model and show that UPEC invades prostate cells via FimH binding to the prostate-specific protein PAPP. A step toward targeted therapies against bacterial prostatitis. 🎉
#UTI #UPEC #Organoids #AMR
New work from the Gonatopoulos-Pournatzis lab!
Online Now: RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria Online now:
RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria
This study introduces CRASP-seq, an RNA-coupled CRISPR screening platform designed to systematically identify regulatory factors and domains of alternative pre-mRNA splicing. Using this technology, ZNF207 is identified as a bona fide splicing regulator through its interaction with U1 snRNP components. ZNF207 modulates aberrant LMNA splicing, a critical event linked to progeria.
dlvr.it
January 6, 2026 at 9:44 AM
New work from the Gonatopoulos-Pournatzis lab!
Reposted by Irene Beusch
A free, open-access library of high-quality organism illustrations for science communication
A free, open-access library of high-quality organism illustrations for science communication
We create vector graphics of model organisms and emerging biological research organisms to enhance our publications. We’re sharing these editable graphics under a CC0 license for other scientists to...
doi.org
December 29, 2025 at 6:03 PM
A free, open-access library of high-quality organism illustrations for science communication
Reposted by Irene Beusch
Excited for this work by Michael Cortazar, an @JagannathanLab Postdoc, to be out as a preprint.
So much hard work went into it, but it was well worth it 🤓
So much hard work went into it, but it was well worth it 🤓
Genomic stop codon scanning reveals quantitative principles of nonsense-mediated mRNA decay https://www.biorxiv.org/content/10.64898/2025.12.20.695734v1
December 25, 2025 at 1:19 AM
Excited for this work by Michael Cortazar, an @JagannathanLab Postdoc, to be out as a preprint.
So much hard work went into it, but it was well worth it 🤓
So much hard work went into it, but it was well worth it 🤓
Reposted by Irene Beusch
RIL-seq boosts the study of sRNAs. Here comes its first application to intracellular bacteria. Plus, 10 years after its characterization, we now present an RNA sponge of Salmonella PinT.
Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social!
doi.org/10.1093/nar/...
Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social!
doi.org/10.1093/nar/...
Intramacrophage RIL-seq uncovers an RNA antagonist of the Salmonella virulence-associated small RNA PinT
Abstract. Salmonella virulence chiefly relies upon two major pathogenicity islands, SPI-1 and SPI-2, which enable host cell invasion and intracellular surv
doi.org
December 27, 2025 at 2:06 PM
RIL-seq boosts the study of sRNAs. Here comes its first application to intracellular bacteria. Plus, 10 years after its characterization, we now present an RNA sponge of Salmonella PinT.
Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social!
doi.org/10.1093/nar/...
Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social!
doi.org/10.1093/nar/...
Reposted by Irene Beusch
Reposted by Irene Beusch
Are you a bachelor or master student anywhere in the world, and would like to come to us to work full-time on a supervised research project? Applications for the 2026 MPIA Summer Internship are open now!
Summer internships
www.mpia.de
December 17, 2025 at 9:13 PM
Are you a bachelor or master student anywhere in the world, and would like to come to us to work full-time on a supervised research project? Applications for the 2026 MPIA Summer Internship are open now!
Reposted by Irene Beusch
Looking for a POSTDOC to work on jumbo phages (those with large genomes and fascinating cell biology), using our latest ASO technology (Gerovac M et al. 2025 Nature) to define RNA export mechanisms as well as to help to advance phage therapy. Here's the job ad.
December 19, 2025 at 10:51 PM
Looking for a POSTDOC to work on jumbo phages (those with large genomes and fascinating cell biology), using our latest ASO technology (Gerovac M et al. 2025 Nature) to define RNA export mechanisms as well as to help to advance phage therapy. Here's the job ad.
Reposted by Irene Beusch
Franziska Faber and I are recruiting shared postdocs, PhD students to work on Fusobacterium & new BGCs. www.helmholtz-hiri.de/fileadmin/HI...
December 12, 2025 at 3:43 PM
Franziska Faber and I are recruiting shared postdocs, PhD students to work on Fusobacterium & new BGCs. www.helmholtz-hiri.de/fileadmin/HI...
Reposted by Irene Beusch
We have an open call for a group leader at the Rudolf Virchow Center for Integrative and Translational Bioimaging in Würzburg, Germany.
Generous starting package, vibrant and highly interdisciplinary biomedical research environment.
www.nature.com/naturecareer...
Please spread the word.
Generous starting package, vibrant and highly interdisciplinary biomedical research environment.
www.nature.com/naturecareer...
Please spread the word.
Group Leader (f/m/d) at the Rudolf Virchow Center for Integrative and Translational Bioimaging - Würzburg (Stadt), Bayern (DE) job with University of Würzburg - Rudolf Virchow Center for Integrative a...
The Rudolf Virchow Center for Integrative and Translational Bioimaging (RVZ) ist now inviting applications for the position of Group Leader (f/m/d).
www.nature.com
November 21, 2025 at 9:12 PM
We have an open call for a group leader at the Rudolf Virchow Center for Integrative and Translational Bioimaging in Würzburg, Germany.
Generous starting package, vibrant and highly interdisciplinary biomedical research environment.
www.nature.com/naturecareer...
Please spread the word.
Generous starting package, vibrant and highly interdisciplinary biomedical research environment.
www.nature.com/naturecareer...
Please spread the word.
Reposted by Irene Beusch
🔊 Interested in doing a PhD on RNA-binding proteins in an abundant microbiota species and becoming a member of the German Priority Programme “Illuminating Gene Functions in the Human Gut Microbiome”? Apply here: www.uni-wuerzburg.de/karriere/sin...
Job offer for a PhD student position at the Chair of Microbiology
www.uni-wuerzburg.de
December 1, 2025 at 9:20 AM
🔊 Interested in doing a PhD on RNA-binding proteins in an abundant microbiota species and becoming a member of the German Priority Programme “Illuminating Gene Functions in the Human Gut Microbiome”? Apply here: www.uni-wuerzburg.de/karriere/sin...
Reposted by Irene Beusch
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
November 18, 2025 at 10:18 AM
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
Reposted by Irene Beusch
Her sister wrote my favorite essay about her. She points out that RF would have been famous even if she'd never looked at DNA
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Remembering my sister Rosalind Franklin
Rosalind Franklin died of ovarian cancer in 1958 aged 37 years. Sympathy and feminism
have combined to give us her familiar image as a downtrodden woman scientist, brilliant
but neglected, a heroine t...
www.thelancet.com
November 7, 2025 at 11:20 PM
Her sister wrote my favorite essay about her. She points out that RF would have been famous even if she'd never looked at DNA
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Reposted by Irene Beusch
KATMAP infers splicing factor activity and regulatory targets from knockdown data - @daspliceisright.bsky.social go.nature.com/47ycrMJ
KATMAP infers splicing factor activity and regulatory targets from knockdown data - Nature Biotechnology
A biophysical model uses knockdown or overexpression data to infer splicing factor activity.
go.nature.com
November 4, 2025 at 3:13 PM
KATMAP infers splicing factor activity and regulatory targets from knockdown data - @daspliceisright.bsky.social go.nature.com/47ycrMJ
Reposted by Irene Beusch
Excited to share my first PhD student’s @biorxivpreprint.bsky.social!
Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules!
Check it out!
www.biorxiv.org/content/10.1...
Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules!
Check it out!
www.biorxiv.org/content/10.1...
November 1, 2025 at 5:56 AM
Excited to share my first PhD student’s @biorxivpreprint.bsky.social!
Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules!
Check it out!
www.biorxiv.org/content/10.1...
Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules!
Check it out!
www.biorxiv.org/content/10.1...
Reposted by Irene Beusch
Calling all Jr RNA Scientists: We are recruiting 2 new RNA Society Jr Sci Reps to lead existing and new initiatives for engaging junior members over the next two years! Details for submitting applications below. @rnasociety.bsky.social
October 21, 2025 at 3:14 PM
Calling all Jr RNA Scientists: We are recruiting 2 new RNA Society Jr Sci Reps to lead existing and new initiatives for engaging junior members over the next two years! Details for submitting applications below. @rnasociety.bsky.social
Reposted by Irene Beusch
Are you interested in studying RNA phages? We are looking for a PhD student and a postdoc to join the lab!
For more information and how to apply, see below 👇
Please RT!
For more information and how to apply, see below 👇
Please RT!
📢 The #HIRI is looking for a #postdoc & a #PhD student to join the research group of @jenshoer.bsky.social. His lab focuses on understanding the molecular mechanisms of #phages with #RNA genomes during infection, host takeover & anti-phage defense. 🧫🦠 More info: www.helmholtz-hiri.de/en/jobs-tale...
Working at HIRI
At the HIRI, we do not just value excellent research. Short distances, an open door policy, and a good working atmosphere—this is what distinguishes us from others. Have a look at our current job…
www.helmholtz-hiri.de
October 17, 2025 at 12:52 PM
Are you interested in studying RNA phages? We are looking for a PhD student and a postdoc to join the lab!
For more information and how to apply, see below 👇
Please RT!
For more information and how to apply, see below 👇
Please RT!
Reposted by Irene Beusch
Thrilled to share our work on transcription initiation and termination being spatially coordinated out today in Science! www.science.org/doi/10.1126/...
mRNA initiation and termination are spatially coordinated
Transcriptional initiation and termination decisions drive messenger RNA (mRNA) isoform diversity but the relationship between them remains poorly understood. By systematically profiling joint usage o...
www.science.org
October 10, 2025 at 6:14 PM
Thrilled to share our work on transcription initiation and termination being spatially coordinated out today in Science! www.science.org/doi/10.1126/...
Reposted by Irene Beusch
My lab is hiring a postdoc! Official job ad and application instructions here:
healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...
Current deadline says October 13, but this will be extended to be open for ~2 weeks.
healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...
Current deadline says October 13, but this will be extended to be open for ~2 weeks.
Research Affiliate I (Post Doctoral)
Applications to be submitted by October 13, 2025 Compensation Grade: P99 (Research Affiliate I) Compensation Details: Minimum: $62,353.20 - Maximum: $62,353.20 Annually Positions with a designated wor...
healthresearch.wd1.myworkdayjobs.com
October 10, 2025 at 6:44 PM
My lab is hiring a postdoc! Official job ad and application instructions here:
healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...
Current deadline says October 13, but this will be extended to be open for ~2 weeks.
healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...
Current deadline says October 13, but this will be extended to be open for ~2 weeks.
Reposted by Irene Beusch
Love RNA biology?
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
PIWI clade Argonautes are essential for transposon silencing. Without them, animals are sterile due to massive transposon activity.
But how does piRNA-guided target interaction translate into silencing?
PhD student Júlia Portell Montserrat has an intriguing answer
www.cell.com/molecular-ce...
But how does piRNA-guided target interaction translate into silencing?
PhD student Júlia Portell Montserrat has an intriguing answer
www.cell.com/molecular-ce...
September 18, 2025 at 2:34 PM
Love RNA biology?
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
Reposted by Irene Beusch
As part of this grant, I have a vacancy out for a PhD student to join our super nice team. It closes on September 9 (Tuesday).
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
PhD position in Gene Regulation
Are you excited about studying the crucial process of transcription? Join our supportive, young and growing team!
www.uu.nl
September 4, 2025 at 11:48 AM
As part of this grant, I have a vacancy out for a PhD student to join our super nice team. It closes on September 9 (Tuesday).
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
Reposted by Irene Beusch
Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!
August 25, 2025 at 8:03 PM
Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!
Reposted by Irene Beusch
Our collaboration with Tony Mustoe's lab us out today. MPRA libraries and possible cryptic splicing in MPRA reporters, or reporters in general. The additional novelty here is that such events are controlled or influenced by AU-rich sequences.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
U-rich elements drive pervasive cryptic splicing in 3’ UTR massively parallel reporter assays - Nature Communications
Massively parallel reporter assays (MPRAs) are powerful technologies for measuring the impact of non-coding sequences on gene expression. Here, the authors demonstrate that MPRA reporters often underg...
www.nature.com
July 25, 2025 at 10:17 AM
Our collaboration with Tony Mustoe's lab us out today. MPRA libraries and possible cryptic splicing in MPRA reporters, or reporters in general. The additional novelty here is that such events are controlled or influenced by AU-rich sequences.
www.nature.com/articles/s41...
www.nature.com/articles/s41...