Irene Beusch
@pauletteoctopus.bsky.social
junior group leader at University of Würzburg || RNA biologist with a 🖤 for splicing || science & 🎨, #firstgen www.beuschlab.org
Reposted by Irene Beusch
Her sister wrote my favorite essay about her. She points out that RF would have been famous even if she'd never looked at DNA
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Remembering my sister Rosalind Franklin
Rosalind Franklin died of ovarian cancer in 1958 aged 37 years. Sympathy and feminism
have combined to give us her familiar image as a downtrodden woman scientist, brilliant
but neglected, a heroine t...
www.thelancet.com
November 7, 2025 at 11:20 PM
Her sister wrote my favorite essay about her. She points out that RF would have been famous even if she'd never looked at DNA
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Reposted by Irene Beusch
KATMAP infers splicing factor activity and regulatory targets from knockdown data - @daspliceisright.bsky.social go.nature.com/47ycrMJ
KATMAP infers splicing factor activity and regulatory targets from knockdown data - Nature Biotechnology
A biophysical model uses knockdown or overexpression data to infer splicing factor activity.
go.nature.com
November 4, 2025 at 3:13 PM
KATMAP infers splicing factor activity and regulatory targets from knockdown data - @daspliceisright.bsky.social go.nature.com/47ycrMJ
Reposted by Irene Beusch
Excited to share my first PhD student’s @biorxivpreprint.bsky.social!
Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules!
Check it out!
www.biorxiv.org/content/10.1...
Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules!
Check it out!
www.biorxiv.org/content/10.1...
November 1, 2025 at 5:56 AM
Excited to share my first PhD student’s @biorxivpreprint.bsky.social!
Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules!
Check it out!
www.biorxiv.org/content/10.1...
Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules!
Check it out!
www.biorxiv.org/content/10.1...
Reposted by Irene Beusch
Calling all Jr RNA Scientists: We are recruiting 2 new RNA Society Jr Sci Reps to lead existing and new initiatives for engaging junior members over the next two years! Details for submitting applications below. @rnasociety.bsky.social
October 21, 2025 at 3:14 PM
Calling all Jr RNA Scientists: We are recruiting 2 new RNA Society Jr Sci Reps to lead existing and new initiatives for engaging junior members over the next two years! Details for submitting applications below. @rnasociety.bsky.social
Reposted by Irene Beusch
Are you interested in studying RNA phages? We are looking for a PhD student and a postdoc to join the lab!
For more information and how to apply, see below 👇
Please RT!
For more information and how to apply, see below 👇
Please RT!
📢 The #HIRI is looking for a #postdoc & a #PhD student to join the research group of @jenshoer.bsky.social. His lab focuses on understanding the molecular mechanisms of #phages with #RNA genomes during infection, host takeover & anti-phage defense. 🧫🦠 More info: www.helmholtz-hiri.de/en/jobs-tale...
Working at HIRI
At the HIRI, we do not just value excellent research. Short distances, an open door policy, and a good working atmosphere—this is what distinguishes us from others. Have a look at our current job…
www.helmholtz-hiri.de
October 17, 2025 at 12:52 PM
Are you interested in studying RNA phages? We are looking for a PhD student and a postdoc to join the lab!
For more information and how to apply, see below 👇
Please RT!
For more information and how to apply, see below 👇
Please RT!
Reposted by Irene Beusch
Thrilled to share our work on transcription initiation and termination being spatially coordinated out today in Science! www.science.org/doi/10.1126/...
mRNA initiation and termination are spatially coordinated
Transcriptional initiation and termination decisions drive messenger RNA (mRNA) isoform diversity but the relationship between them remains poorly understood. By systematically profiling joint usage o...
www.science.org
October 10, 2025 at 6:14 PM
Thrilled to share our work on transcription initiation and termination being spatially coordinated out today in Science! www.science.org/doi/10.1126/...
Reposted by Irene Beusch
My lab is hiring a postdoc! Official job ad and application instructions here:
healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...
Current deadline says October 13, but this will be extended to be open for ~2 weeks.
healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...
Current deadline says October 13, but this will be extended to be open for ~2 weeks.
Research Affiliate I (Post Doctoral)
Applications to be submitted by October 13, 2025 Compensation Grade: P99 (Research Affiliate I) Compensation Details: Minimum: $62,353.20 - Maximum: $62,353.20 Annually Positions with a designated wor...
healthresearch.wd1.myworkdayjobs.com
October 10, 2025 at 6:44 PM
My lab is hiring a postdoc! Official job ad and application instructions here:
healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...
Current deadline says October 13, but this will be extended to be open for ~2 weeks.
healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...
Current deadline says October 13, but this will be extended to be open for ~2 weeks.
Reposted by Irene Beusch
Love RNA biology?
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
PIWI clade Argonautes are essential for transposon silencing. Without them, animals are sterile due to massive transposon activity.
But how does piRNA-guided target interaction translate into silencing?
PhD student Júlia Portell Montserrat has an intriguing answer
www.cell.com/molecular-ce...
But how does piRNA-guided target interaction translate into silencing?
PhD student Júlia Portell Montserrat has an intriguing answer
www.cell.com/molecular-ce...
September 18, 2025 at 2:34 PM
Love RNA biology?
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
Reposted by Irene Beusch
As part of this grant, I have a vacancy out for a PhD student to join our super nice team. It closes on September 9 (Tuesday).
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
PhD position in Gene Regulation
Are you excited about studying the crucial process of transcription? Join our supportive, young and growing team!
www.uu.nl
September 4, 2025 at 11:48 AM
As part of this grant, I have a vacancy out for a PhD student to join our super nice team. It closes on September 9 (Tuesday).
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
Reposted by Irene Beusch
Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!
August 25, 2025 at 8:03 PM
Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!
Reposted by Irene Beusch
Our collaboration with Tony Mustoe's lab us out today. MPRA libraries and possible cryptic splicing in MPRA reporters, or reporters in general. The additional novelty here is that such events are controlled or influenced by AU-rich sequences.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
U-rich elements drive pervasive cryptic splicing in 3’ UTR massively parallel reporter assays - Nature Communications
Massively parallel reporter assays (MPRAs) are powerful technologies for measuring the impact of non-coding sequences on gene expression. Here, the authors demonstrate that MPRA reporters often underg...
www.nature.com
July 25, 2025 at 10:17 AM
Our collaboration with Tony Mustoe's lab us out today. MPRA libraries and possible cryptic splicing in MPRA reporters, or reporters in general. The additional novelty here is that such events are controlled or influenced by AU-rich sequences.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Irene Beusch
Reposted by Irene Beusch
Deadline for applications is this Friday!!!
BME UNITE @bmeunite.bsky.social is launching Year 5 of our Future Faculty Program! BME Faculty candidates from marginalized groups on the job market - apply here by July 11th to present your work and receive mentorship to successfully navigate the academic job market: forms.gle/sVto2GRQauNA...
July 7, 2025 at 1:48 PM
Deadline for applications is this Friday!!!
Reposted by Irene Beusch
The IncaRNAto lab is seeking a motivated #PhD candidate, interested in studying #RNA structural ensemble dynamics in living cells. Here's the link to the vacancy: www.rug.nl/about-ug/wor.... Please share!
Vacatures bij de RUG
www.rug.nl
July 1, 2025 at 8:20 PM
The IncaRNAto lab is seeking a motivated #PhD candidate, interested in studying #RNA structural ensemble dynamics in living cells. Here's the link to the vacancy: www.rug.nl/about-ug/wor.... Please share!
Reposted by Irene Beusch
My postdoctoral work with @hitenmadhani.bsky.social is now online at @cp-cell.bsky.social! We profiled the fitness of >4300 Cryptococcus neoformans deletion strains in >140 conditions, identifying unexpected mammalian-like biology and drivers of fungal pathogenesis.
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Phenotypic landscape of an invasive fungal pathogen reveals its unique biology
The construction and high-precision fitness profiling of a C. neoformans knockout
library reveals a high-resolution functional map of its genome and allowed for the
identification of fungal analogs of...
www.cell.com
June 11, 2025 at 4:00 PM
My postdoctoral work with @hitenmadhani.bsky.social is now online at @cp-cell.bsky.social! We profiled the fitness of >4300 Cryptococcus neoformans deletion strains in >140 conditions, identifying unexpected mammalian-like biology and drivers of fungal pathogenesis.
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
„AI is unavoidable, and even if a single query is low-impact, governments and companies are now shaping a much larger energy future around AI’s needs.“
this is really interesting about AI and energy use/the environment- I feel it's been hard to get concrete info about this www.technologyreview.com/2025/05/20/1...
We did the math on AI’s energy footprint. Here’s the story you haven’t heard.
The emissions from individual AI text, image, and video queries seem small—until you add up what the industry isn’t tracking and consider where it’s heading next.
www.technologyreview.com
May 27, 2025 at 12:41 PM
„AI is unavoidable, and even if a single query is low-impact, governments and companies are now shaping a much larger energy future around AI’s needs.“
Reposted by Irene Beusch
Very excited to share our new paper out now in
@MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...
@MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...
U1 snRNP regulates alternative promoter activity by inhibiting premature polyadenylation
Kim et al. uncover a role for U1 snRNP in regulating internal promoter activity. Beyond
its canonical role in splicing, U1 snRNP suppresses premature polyadenylation, enabling
upstream transcription t...
www.cell.com
May 16, 2025 at 3:35 PM
Very excited to share our new paper out now in
@MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...
@MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...
Reposted by Irene Beusch
Hello Community!
Are you a postdoc/grad student preparing to launch a faculty search? Do you have a track record of excellence in research, leadership, mentorship & community engagement? Apply to the 2025 Next Generation Faculty Symposium: www.berkeleystanfordnextgensymposium.com! Pls repost! (1/3)
Are you a postdoc/grad student preparing to launch a faculty search? Do you have a track record of excellence in research, leadership, mentorship & community engagement? Apply to the 2025 Next Generation Faculty Symposium: www.berkeleystanfordnextgensymposium.com! Pls repost! (1/3)
April 21, 2025 at 7:21 PM
Hello Community!
Are you a postdoc/grad student preparing to launch a faculty search? Do you have a track record of excellence in research, leadership, mentorship & community engagement? Apply to the 2025 Next Generation Faculty Symposium: www.berkeleystanfordnextgensymposium.com! Pls repost! (1/3)
Are you a postdoc/grad student preparing to launch a faculty search? Do you have a track record of excellence in research, leadership, mentorship & community engagement? Apply to the 2025 Next Generation Faculty Symposium: www.berkeleystanfordnextgensymposium.com! Pls repost! (1/3)
5EU labelling may have some undesired consequences or effects depending on labelling pulse concentration & duration www.biorxiv.org/content/10.1... #RNAsky
5-ethynyluridine perturbs nuclear RNA metabolism to promote the nuclear accumulation of TDP-43 and other RNA binding proteins
TDP-43, an essential nucleic acid binding protein and splicing regulator, is broadly disrupted in neurodegeneration. TDP-43 nuclear localization and function depend on the abundance of its nuclear RNA...
www.biorxiv.org
April 21, 2025 at 5:06 PM
5EU labelling may have some undesired consequences or effects depending on labelling pulse concentration & duration www.biorxiv.org/content/10.1... #RNAsky
Reposted by Irene Beusch
Are you a postdoc ready for transition to an independent position? You connect infection biology with cutting-edge structural biology or multimodal imaging? Are you aware of such a colleague?
I am seeking speakers for "The Next Generation in Infection Biology" microsymposium on June 6 2025.
I am seeking speakers for "The Next Generation in Infection Biology" microsymposium on June 6 2025.
April 16, 2025 at 8:16 AM
Are you a postdoc ready for transition to an independent position? You connect infection biology with cutting-edge structural biology or multimodal imaging? Are you aware of such a colleague?
I am seeking speakers for "The Next Generation in Infection Biology" microsymposium on June 6 2025.
I am seeking speakers for "The Next Generation in Infection Biology" microsymposium on June 6 2025.
Interesting blog post by Yoseph Barash on tissue specific splicing prediction: biociphers.wordpress.com/2025/04/09/t...
Tissue-specific splicing prediction – What’s in a name, what’s in a claim, and are target functions all the same?
In today’s blog post, I want to discuss some work/claims related to a topic that has been one of my lab’s focus areas – predicting tissue-specific alternative splicing (AS) of RNA. Some backg…
biociphers.wordpress.com
April 10, 2025 at 4:39 PM
Interesting blog post by Yoseph Barash on tissue specific splicing prediction: biociphers.wordpress.com/2025/04/09/t...
Reposted by Irene Beusch
Our PhD program application deadline is near, apply now! In our open present call, we have 25+ fully funded positions for talented Master/MSc students. Start your application by 11 April 2025
training.vbc.ac.at/p...
training.vbc.ac.at/p...
April 6, 2025 at 6:46 AM
Our PhD program application deadline is near, apply now! In our open present call, we have 25+ fully funded positions for talented Master/MSc students. Start your application by 11 April 2025
training.vbc.ac.at/p...
training.vbc.ac.at/p...
Reposted by Irene Beusch
Two reminders for aspiring PhD candidates: April 3 is the information session, and April 11 is the application deadline. See below for more info.
Our team is going to answer student questions about our PhD program on 3 April! We have 25+ fully-funded positions in this call. Pass on or share with your colleagues! Sign up here
ow.ly/ptFT50PNJV2
ow.ly/ptFT50PNJV2
April 2, 2025 at 7:50 AM
Two reminders for aspiring PhD candidates: April 3 is the information session, and April 11 is the application deadline. See below for more info.
loved the pre-print. looking forward to reading the final manuscript!
I'm excited to share our latest publication on co-transcriptional RNA folding in a eukaryote! Great work by Leo Schärfen with collaboration from Isaac Vock and Matt Simon! @leoschaerfen.bsky.social @mattdsimon.bsky.social
Take a peek here authors.elsevier.com/a/1kpxo_Oylr...
Take a peek here authors.elsevier.com/a/1kpxo_Oylr...
authors.elsevier.com
March 26, 2025 at 12:51 PM
loved the pre-print. looking forward to reading the final manuscript!