Tim Overton
@overtonlab.bsky.social
Microbiologist, interested in using bugs to do interesting things and also how to kill them.
https://research.birmingham.ac.uk/en/persons/tim-overton
ORCID: 0000-0003-3050-2549
https://research.birmingham.ac.uk/en/persons/tim-overton
ORCID: 0000-0003-3050-2549
Some old buildings in Gloucestershire from the weekend
October 29, 2025 at 10:41 AM
Some old buildings in Gloucestershire from the weekend
New PhDs in my lab starting 2026!
Funded projects as part of the MIBTP centre (funded by BBSRC) now open for applications: warwick.ac.uk/fac/cross_fa...
Are you interested in biofilms? We have a couple of projects - looking at the links between energy metabolism and biofilms - and electricity!
Funded projects as part of the MIBTP centre (funded by BBSRC) now open for applications: warwick.ac.uk/fac/cross_fa...
Are you interested in biofilms? We have a couple of projects - looking at the links between energy metabolism and biofilms - and electricity!
Dr Tim Overton
Dr Tim Overton
warwick.ac.uk
October 14, 2025 at 8:29 AM
New PhDs in my lab starting 2026!
Funded projects as part of the MIBTP centre (funded by BBSRC) now open for applications: warwick.ac.uk/fac/cross_fa...
Are you interested in biofilms? We have a couple of projects - looking at the links between energy metabolism and biofilms - and electricity!
Funded projects as part of the MIBTP centre (funded by BBSRC) now open for applications: warwick.ac.uk/fac/cross_fa...
Are you interested in biofilms? We have a couple of projects - looking at the links between energy metabolism and biofilms - and electricity!
Reposted by Tim Overton
Job opportunity in my lab! We're looking for a post-doc to come join us for an exciting project exploring the evolution of #AMR and #hypervirulence in #klebsiella. Please share!! @unibirmingham.bsky.social Details: www.jobs.ac.uk/job/DOV067/r...
Research Fellow at University of Birmingham
Apply now for the Research Fellow role on jobs.ac.uk - the leading job board for higher education jobs. View details.
www.jobs.ac.uk
October 2, 2025 at 10:56 AM
Job opportunity in my lab! We're looking for a post-doc to come join us for an exciting project exploring the evolution of #AMR and #hypervirulence in #klebsiella. Please share!! @unibirmingham.bsky.social Details: www.jobs.ac.uk/job/DOV067/r...
New preprint! www.biorxiv.org/content/10.1...
GFP is a useful protein to optimise production of proteins in the cytoplasm, but does not work well in the periplasm. We tested if two newer variants of GFP (sfGPF and cfSGFP2) can be used to improve periplasmic protein production.
GFP is a useful protein to optimise production of proteins in the cytoplasm, but does not work well in the periplasm. We tested if two newer variants of GFP (sfGPF and cfSGFP2) can be used to improve periplasmic protein production.
| bioRxiv
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
September 30, 2025 at 9:29 AM
New preprint! www.biorxiv.org/content/10.1...
GFP is a useful protein to optimise production of proteins in the cytoplasm, but does not work well in the periplasm. We tested if two newer variants of GFP (sfGPF and cfSGFP2) can be used to improve periplasmic protein production.
GFP is a useful protein to optimise production of proteins in the cytoplasm, but does not work well in the periplasm. We tested if two newer variants of GFP (sfGPF and cfSGFP2) can be used to improve periplasmic protein production.
Had a great time in London this week, including a visit to the always excellent Japan House for their exhibition of pictograms
August 30, 2025 at 9:57 AM
Had a great time in London this week, including a visit to the always excellent Japan House for their exhibition of pictograms
New paper! A fun collaboration with Aneika Leney's group (@leneyms.bsky.social), looking for cyanobacteria in lake water using novel mass spectrometry approaches (and comparing with flow cytometry) pubs.acs.org/doi/full/10....
pubs.acs.org
July 31, 2025 at 12:04 PM
New paper! A fun collaboration with Aneika Leney's group (@leneyms.bsky.social), looking for cyanobacteria in lake water using novel mass spectrometry approaches (and comparing with flow cytometry) pubs.acs.org/doi/full/10....
A surprise sighting yesterday in Birmingham - two Scarlet Tiger moths on a car tyre!
June 5, 2025 at 8:11 AM
A surprise sighting yesterday in Birmingham - two Scarlet Tiger moths on a car tyre!
Exciting new PhD project!
Are you interested in the microbiology of the mouth, and how we could develop new oral care products to reduce harmful bacteria while helping beneficial ones?
Fully funded by EPSRC (UK students only) and working with Colgate.
www.birmingham.ac.uk/documents/co...
Are you interested in the microbiology of the mouth, and how we could develop new oral care products to reduce harmful bacteria while helping beneficial ones?
Fully funded by EPSRC (UK students only) and working with Colgate.
www.birmingham.ac.uk/documents/co...
www.birmingham.ac.uk
May 16, 2025 at 11:35 AM
Exciting new PhD project!
Are you interested in the microbiology of the mouth, and how we could develop new oral care products to reduce harmful bacteria while helping beneficial ones?
Fully funded by EPSRC (UK students only) and working with Colgate.
www.birmingham.ac.uk/documents/co...
Are you interested in the microbiology of the mouth, and how we could develop new oral care products to reduce harmful bacteria while helping beneficial ones?
Fully funded by EPSRC (UK students only) and working with Colgate.
www.birmingham.ac.uk/documents/co...
Back at work now but Scotland last week was pretty good
April 30, 2025 at 7:29 PM
Back at work now but Scotland last week was pretty good
Chiffchaff singing outside my office window reminds me that spring is very much here.
April 2, 2025 at 8:28 AM
Chiffchaff singing outside my office window reminds me that spring is very much here.
Concert today in symphony hall - Stravinsky!
March 23, 2025 at 12:01 PM
Concert today in symphony hall - Stravinsky!
Reposted by Tim Overton
Feb. 2, 1925: Dogs save the city of Nome, Alaska. A team of huskies races into the dipththeria-stricken city dragging a sled that carries enough antitoxin to halt the epidemic. The last leg of the heroic relay is directed by musher Gunnar Kaasen and his lead dog, Balto. 1/10
February 2, 2025 at 3:17 PM
Feb. 2, 1925: Dogs save the city of Nome, Alaska. A team of huskies races into the dipththeria-stricken city dragging a sled that carries enough antitoxin to halt the epidemic. The last leg of the heroic relay is directed by musher Gunnar Kaasen and his lead dog, Balto. 1/10
Tomorrow - playing with solihullsymphony.org.uk in Dorridge, an Opera Gala with Puccini / Wagner / Verdi et al.
Home - Solihull Symphony Orchestra
Solihull Symphony Orchestra is a lively and enthusiastic group of non-professional musicians who enjoy taking on the challenge of a diverse and varied repertoire. Our members span an age range from un...
solihullsymphony.org.uk
January 31, 2025 at 1:08 PM
Tomorrow - playing with solihullsymphony.org.uk in Dorridge, an Opera Gala with Puccini / Wagner / Verdi et al.
Reposted by Tim Overton
It's been a terrible week. A terrible, terrible week. The worst people on earth are full of energy and vigour, the best are defined by anxiety and self-doubt. Here are three simple rules to surviving the next four years, because by God we'll need them iandunt.substack.com/p/a-little-b...
A little bit of hope after a terrible week
A survival guide to the next four years.
iandunt.substack.com
January 10, 2025 at 12:00 PM
It's been a terrible week. A terrible, terrible week. The worst people on earth are full of energy and vigour, the best are defined by anxiety and self-doubt. Here are three simple rules to surviving the next four years, because by God we'll need them iandunt.substack.com/p/a-little-b...
I'm trying to listen to some new music this year, and starting alphabetically on spotify. This week's discovery - Hendrik Andriessen, father of Louis Andriessen
January 8, 2025 at 11:42 AM
I'm trying to listen to some new music this year, and starting alphabetically on spotify. This week's discovery - Hendrik Andriessen, father of Louis Andriessen
Reposted by Tim Overton
I find it comforting that I'm partly made up of bacteria and fungi and other little critters. My microbiota make me want to be gentle with myself, even when I'm having a bad day. How cool is it to be a planet that has the capacity to think about and even love its inhabitants?
November 25, 2024 at 1:59 AM
I find it comforting that I'm partly made up of bacteria and fungi and other little critters. My microbiota make me want to be gentle with myself, even when I'm having a bad day. How cool is it to be a planet that has the capacity to think about and even love its inhabitants?
Concert tomorrow with the Solihull Symphony Orchestra - marking Bruckner 200 with a performance of his 4th Symphony. Quite a bit for the 📯 to do!
solihullsymphony.org.uk/our-next-con...
solihullsymphony.org.uk/our-next-con...
solihullsymphony.org.uk
November 22, 2024 at 2:52 PM
Concert tomorrow with the Solihull Symphony Orchestra - marking Bruckner 200 with a performance of his 4th Symphony. Quite a bit for the 📯 to do!
solihullsymphony.org.uk/our-next-con...
solihullsymphony.org.uk/our-next-con...
Reposted by Tim Overton
I have three PhD studentships available currently through the MIBTP DTP warwick.ac.uk/fac/cross_fa... on different aspects of the respiratory microbiome, interaction with mucin with @lucyicm.bsky.social, the resistome with Dr Michelle Buckner and pathobionts with @bacterioskeptic.bsky.social
Dr Michael Cox
Dr Michael Cox
warwick.ac.uk
November 18, 2024 at 3:50 PM
I have three PhD studentships available currently through the MIBTP DTP warwick.ac.uk/fac/cross_fa... on different aspects of the respiratory microbiome, interaction with mucin with @lucyicm.bsky.social, the resistome with Dr Michelle Buckner and pathobionts with @bacterioskeptic.bsky.social
Reposted by Tim Overton
Reposted by Tim Overton
MIBTP PhD applications are now open! There are three associated with my lab.1) infant gut microbes and human milk oligosaccharides with @halllab.bsky.social 2) respiratory microbiome nutrition with Mike Cox 3) mucus-producing organoids with Amanda Rossiter!
🧪✨
warwick.ac.uk/fac/cross_fa...
🧪✨
warwick.ac.uk/fac/cross_fa...
November 15, 2024 at 5:18 PM
MIBTP PhD applications are now open! There are three associated with my lab.1) infant gut microbes and human milk oligosaccharides with @halllab.bsky.social 2) respiratory microbiome nutrition with Mike Cox 3) mucus-producing organoids with Amanda Rossiter!
🧪✨
warwick.ac.uk/fac/cross_fa...
🧪✨
warwick.ac.uk/fac/cross_fa...
New PhD projects as part of the BBSRC-funded MIBTP scheme! Fully funded and open to home and overseas students! Are you interested in bioprocesses, antimicrobial resistance, virulence, or biofilms?
November 15, 2024 at 4:49 PM
New PhD projects as part of the BBSRC-funded MIBTP scheme! Fully funded and open to home and overseas students! Are you interested in bioprocesses, antimicrobial resistance, virulence, or biofilms?
Reposted by Tim Overton
Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics.
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
November 13, 2024 at 12:46 PM
Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics.
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
New paper! What happens when you apply vibration to bacteria? We asked this question for E. coli and revealed that attachment decreases. This response requires live cells and involves membrane potential.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Nanovibrational Stimulation of Escherichia coli Mitigates Surface Adhesion by Altering Cell Membrane Potential
Mechanical forces shape living matter from the macro- to the microscale as both eukaryotic and prokaryotic cells are force wielders and sensors. However, whereas such forces have been used to control ...
pubs.acs.org
October 23, 2024 at 9:51 AM
New paper! What happens when you apply vibration to bacteria? We asked this question for E. coli and revealed that attachment decreases. This response requires live cells and involves membrane potential.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
New paper! Deactivating efflux pumps results in major changes to bacterial physiology. We demonstrate that knockout of the major efflux pump AcrB results in changes to membrane potential.
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Efflux pumps mediate changes to fundamental bacterial physiology via membrane potential | mBio
We demonstrate for the first time that deactivation of efflux pumps brings about changes
to gross bacterial physiology and metabolism. Rather than simply being a response
to noxious substances, efflux...
journals.asm.org
September 9, 2024 at 3:21 PM
New paper! Deactivating efflux pumps results in major changes to bacterial physiology. We demonstrate that knockout of the major efflux pump AcrB results in changes to membrane potential.
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...