Stefan Oehlers
@oehlerslab.org
Principal Investigator, Bacterial Pathogenesis Lab (A*STAR ID Labs, Singapore)
@astar-idlabs.bsky.social
Zebrafish models of infection and immunity
www.oehlerslab.org
@astar-idlabs.bsky.social
Zebrafish models of infection and immunity
www.oehlerslab.org
Pinned
Stefan Oehlers
@oehlerslab.org
· May 9
Why are prior and concurrent #TB such huge risk factors for M. abscessus infection? #zebrafish preprint lead by our research officer Denise Wee discovers tuberculous granulomas (yellow blob) act as a safe haven for opportunistic mycobacterial pathogens (magenta blobs).
Work from the most mysterious scientist in @astar-idlabs.bsky.social on his cuckoo flu virus. This is what happens when he was told to stop at 50 passages but kept going out of spite.
First big piece of research from our SG lab: Fadi's work with Chris Brooke's lab. Flu serially passaged 80X selects a defective genome with improved competition, but is nonviable as a full virus!
Notable improvement & safety for DVGs as antiviral RNA therapies!
www.biorxiv.org/content/10.1...
Notable improvement & safety for DVGs as antiviral RNA therapies!
www.biorxiv.org/content/10.1...
Longitudinal analysis of influenza A virus deletion-containing viral genomes reveals key determinants of co-evolutionary dynamics and interference
The substantial genetic diversity generated during influenza A virus replication facilitates both evasion of pre-existing host immunity and cross-species emergence. A major contributor to this diversi...
www.biorxiv.org
November 4, 2025 at 9:59 AM
Work from the most mysterious scientist in @astar-idlabs.bsky.social on his cuckoo flu virus. This is what happens when he was told to stop at 50 passages but kept going out of spite.
Reposted by Stefan Oehlers
Submit your poster abstract for the #2026SCZI before November 5th! There is only one week left to submit for this prestigious #zebrafish meeting. Submit, attend, and advance your zebrafish knowledge with fellow #PIs from around the world!
11th Strategic Conference of Zebrafish Investigators | IZFS - International Zebrafish Society
About SCZI 2026
www.izfs.org
October 29, 2025 at 8:31 PM
Submit your poster abstract for the #2026SCZI before November 5th! There is only one week left to submit for this prestigious #zebrafish meeting. Submit, attend, and advance your zebrafish knowledge with fellow #PIs from around the world!
Reposted by Stefan Oehlers
Well, this is a brilliant #IDSky article that cuts close to the bone! 😬
Reframes #academia as an infection for which the causative organism may be less easy to define, but that can be just as insidious on affected individuals (clinical academics)!
#AcademicSky #MedSky 🧪 @cidjournal.bsky.social
Reframes #academia as an infection for which the causative organism may be less easy to define, but that can be just as insidious on affected individuals (clinical academics)!
#AcademicSky #MedSky 🧪 @cidjournal.bsky.social
Infected With the Academic Bug
It starts innocently. A paper you’re proud of, the thrill of seeing your name on PubMed. Everyone is genuinely happy for you; you’re a threat to no one. Bu
academic.oup.com
October 27, 2025 at 6:32 PM
Well, this is a brilliant #IDSky article that cuts close to the bone! 😬
Reframes #academia as an infection for which the causative organism may be less easy to define, but that can be just as insidious on affected individuals (clinical academics)!
#AcademicSky #MedSky 🧪 @cidjournal.bsky.social
Reframes #academia as an infection for which the causative organism may be less easy to define, but that can be just as insidious on affected individuals (clinical academics)!
#AcademicSky #MedSky 🧪 @cidjournal.bsky.social
Reposted by Stefan Oehlers
I am delighted to announce that I will be starting as an Assistant Professor at the University of Arizona in Spring 2026. Our lab will study intestinal best4+ cells in zebrafish. We are seeking a lab manager with previous zebrafish experience – come build with us.
surlab-gastro.my.canva.site
surlab-gastro.my.canva.site
Home
surlab-gastro.my.canva.site
October 26, 2025 at 12:41 AM
I am delighted to announce that I will be starting as an Assistant Professor at the University of Arizona in Spring 2026. Our lab will study intestinal best4+ cells in zebrafish. We are seeking a lab manager with previous zebrafish experience – come build with us.
surlab-gastro.my.canva.site
surlab-gastro.my.canva.site
Reposted by Stefan Oehlers
There are only two weeks left to submit your #SCZI2026 Poster Abstracts! Attend the premier meeting for #zebrafish PIs in Singapore January 14-17 and share your science with a global audience!
Registration | IZFS - International Zebrafish Society
Cookie Notice
www.izfs.org
October 22, 2025 at 2:45 PM
There are only two weeks left to submit your #SCZI2026 Poster Abstracts! Attend the premier meeting for #zebrafish PIs in Singapore January 14-17 and share your science with a global audience!
Reposted by Stefan Oehlers
🚨Publication alert: Where does immunotherapy happen? What can the fish teach us about human pathology? And a dendritic cell is having a friend for dinner. Cancer immunology goes live, now in @cp-cell.bsky.social.
Here is a concise summary of a pretty big study 🧵. Let’s go (appetizer👇)
Here is a concise summary of a pretty big study 🧵. Let’s go (appetizer👇)
October 18, 2025 at 5:46 PM
🚨Publication alert: Where does immunotherapy happen? What can the fish teach us about human pathology? And a dendritic cell is having a friend for dinner. Cancer immunology goes live, now in @cp-cell.bsky.social.
Here is a concise summary of a pretty big study 🧵. Let’s go (appetizer👇)
Here is a concise summary of a pretty big study 🧵. Let’s go (appetizer👇)
Bringing us one step closer to the #zebrafish we were promised by generative AI cartoons
elifesciences.org/articles/106...
elifesciences.org/articles/106...
Cross-species insemination reveals mouse sperm ability to enter and cross the fish micropyle
Mouse sperm are unable to bind the zebrafish chorion, yet a subset of hyperactivated sperm can enter and cross the micropyle, suggesting a conserved mechanism of gamete interaction across species.
elifesciences.org
October 18, 2025 at 6:15 AM
Bringing us one step closer to the #zebrafish we were promised by generative AI cartoons
elifesciences.org/articles/106...
elifesciences.org/articles/106...
Reposted by Stefan Oehlers
Join us in Singapore for #SCZI2026! Poster submissions and early bird registration remain open until November 5th. Secure your spot at this exclusive meeting before it is too late! Registration is limited to 200 participants.
Registration | IZFS - International Zebrafish Society
Registration for the 11th IZFC opens on August 13! Use the link below to register!
www.izfs.org
October 16, 2025 at 2:54 PM
Join us in Singapore for #SCZI2026! Poster submissions and early bird registration remain open until November 5th. Secure your spot at this exclusive meeting before it is too late! Registration is limited to 200 participants.
Reposted by Stefan Oehlers
Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei
@sydneylmiles.bsky.social @katholt.bsky.social
🙏to transformative collaborative effort
www.nature.com/articles/s41...
@sydneylmiles.bsky.social @katholt.bsky.social
🙏to transformative collaborative effort
www.nature.com/articles/s41...
October 13, 2025 at 9:48 PM
Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei
@sydneylmiles.bsky.social @katholt.bsky.social
🙏to transformative collaborative effort
www.nature.com/articles/s41...
@sydneylmiles.bsky.social @katholt.bsky.social
🙏to transformative collaborative effort
www.nature.com/articles/s41...
Reposted by Stefan Oehlers
Our new paper on valve disease in aged #zebrafish is out! onlinelibrary.wiley.com/doi/10.1111/... This has been a long running collaborative effort with contributions from lots of great people!
Aged Zebrafish as a Spontaneous Model of Cardiac Valvular Disease
Natural ageing in zebrafish results in spontaneous development of valvular degeneration in both the atrioventricular (AV) and bulboventricular (BV) valves. Aged zebrafish valves are larger and exhibi...
onlinelibrary.wiley.com
October 13, 2025 at 11:01 AM
Our new paper on valve disease in aged #zebrafish is out! onlinelibrary.wiley.com/doi/10.1111/... This has been a long running collaborative effort with contributions from lots of great people!
Reposted by Stefan Oehlers
Only a few days left to apply to join the lab, come have fun with lasers and fish to answer some cool questions along the gut-brain axis. Denmark is also a lovely country to live in!
We are recruiting a postdoc to join our team and study neuroinflammation along the gut-brain axis. Please share it with anyone who may be interested, and do not hesitate to reach out if you have questions.
international.au.dk/about/profil...
international.au.dk/about/profil...
Postdoc position in Neuroinflammation - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - Neurobiology, Aarhus University
international.au.dk
October 10, 2025 at 8:14 AM
Only a few days left to apply to join the lab, come have fun with lasers and fish to answer some cool questions along the gut-brain axis. Denmark is also a lovely country to live in!
Reposted by Stefan Oehlers
Interested in establishing your own research group?
Our support package for new Group Leaders includes:
🥼2 #Postdocs, a technician & 2 PhD students + lab costs
🔬Full access to core facilities
🧪Access to the MCRC #Biobank
✔️Mentorship, #grant advice & more
www.cruk.manchester.ac.uk/career/new-g...
Our support package for new Group Leaders includes:
🥼2 #Postdocs, a technician & 2 PhD students + lab costs
🔬Full access to core facilities
🧪Access to the MCRC #Biobank
✔️Mentorship, #grant advice & more
www.cruk.manchester.ac.uk/career/new-g...
October 8, 2025 at 10:52 AM
Interested in establishing your own research group?
Our support package for new Group Leaders includes:
🥼2 #Postdocs, a technician & 2 PhD students + lab costs
🔬Full access to core facilities
🧪Access to the MCRC #Biobank
✔️Mentorship, #grant advice & more
www.cruk.manchester.ac.uk/career/new-g...
Our support package for new Group Leaders includes:
🥼2 #Postdocs, a technician & 2 PhD students + lab costs
🔬Full access to core facilities
🧪Access to the MCRC #Biobank
✔️Mentorship, #grant advice & more
www.cruk.manchester.ac.uk/career/new-g...
Reposted by Stefan Oehlers
There is less than one month left to register at the early bird rate and join us for #SCZI2026 in Singapore! Register and submit your poster abstract before November 5th here: www.izfs.org/education/11...
Registration | IZFS - International Zebrafish Society
www.izfs.org
October 7, 2025 at 8:20 PM
There is less than one month left to register at the early bird rate and join us for #SCZI2026 in Singapore! Register and submit your poster abstract before November 5th here: www.izfs.org/education/11...
Reposted by Stefan Oehlers
I am biased 😉, but this is an amazing PI and an amazing person, check out this opportunity #immunosky #TB
We are looking to hire post-docs to work on T cell responses to M. tuberculosis infection using murine and NHP models. If you know T cells and wanna work on the top global infectious killer check us out. BSL3 experience not required. The NIH intramural program in Bethesda MD is an amazing place!
September 18, 2025 at 12:44 AM
I am biased 😉, but this is an amazing PI and an amazing person, check out this opportunity #immunosky #TB
Reposted by Stefan Oehlers
My new blog post is about great books on TB!
A Plague That Refuses To Go Away: Spotlight on Great Tuberculosis Books
communities.springernature.com/posts/a-plag...
A Plague That Refuses To Go Away: Spotlight on Great Tuberculosis Books
communities.springernature.com/posts/a-plag...
A Plague That Refuses To Go Away: Spotlight on Great Tuberculosis Books
TB has impacted humans for centuries and profoundly shaped our history. These wonderful books have captured the history, impact, and consequences of this infectious disease that is still haunting huma...
communities.springernature.com
September 15, 2025 at 1:37 AM
My new blog post is about great books on TB!
A Plague That Refuses To Go Away: Spotlight on Great Tuberculosis Books
communities.springernature.com/posts/a-plag...
A Plague That Refuses To Go Away: Spotlight on Great Tuberculosis Books
communities.springernature.com/posts/a-plag...
Reposted by Stefan Oehlers
Deadline This Wednesday: Oral Abstracts and Workshop Proposals for #SCZI2026 are due this Wednesday, Sept 17. Join us in Singapore, where #zebrafish community leaders will present groundbreaking research shaping the future of the field.
11th Strategic Conference of Zebrafish Investigators | IZFS - International Zebrafish Society
Organizers | Registration | Abstracts | Program | Sponsorship | Workshops | Lodging | Financial Assistance
www.izfs.org
September 14, 2025 at 3:15 PM
Deadline This Wednesday: Oral Abstracts and Workshop Proposals for #SCZI2026 are due this Wednesday, Sept 17. Join us in Singapore, where #zebrafish community leaders will present groundbreaking research shaping the future of the field.
Reposted by Stefan Oehlers
From Megan Hayes' elegant PhD thesis, Cressida Madigan Lab UCSD Biological Sciences, using zebrafish model
In TB meningitis, mycobacteria lodge at vessel bifurcations, enlarge vessels, and transiently block brain blood flow—driving oxidative stress and cell death!
journals.plos.org/plosone/arti...
In TB meningitis, mycobacteria lodge at vessel bifurcations, enlarge vessels, and transiently block brain blood flow—driving oxidative stress and cell death!
journals.plos.org/plosone/arti...
September 12, 2025 at 9:53 PM
From Megan Hayes' elegant PhD thesis, Cressida Madigan Lab UCSD Biological Sciences, using zebrafish model
In TB meningitis, mycobacteria lodge at vessel bifurcations, enlarge vessels, and transiently block brain blood flow—driving oxidative stress and cell death!
journals.plos.org/plosone/arti...
In TB meningitis, mycobacteria lodge at vessel bifurcations, enlarge vessels, and transiently block brain blood flow—driving oxidative stress and cell death!
journals.plos.org/plosone/arti...
Reposted by Stefan Oehlers
Really interesting work from our neighbor Clare Smith @dukemedschool.bsky.social starting from CC mice and linking Ctsz to TB infection outcome as well as functional variation in human populations (UW, Case Western, Uganda) and expression in human granulomas (@charliejpyle.bsky.social)
#Tuberculosis severity varies widely between people; why is this? This study uses the #CollaborativeCross mouse panel to identify the protease #cathepsin Z (CTSZ) as a conserved regulator of #TB outcomes via its influence on CXCL1 in mice & in humans @plosbiology.org 🧪 plos.io/4phwRA8
September 10, 2025 at 5:32 PM
Really interesting work from our neighbor Clare Smith @dukemedschool.bsky.social starting from CC mice and linking Ctsz to TB infection outcome as well as functional variation in human populations (UW, Case Western, Uganda) and expression in human granulomas (@charliejpyle.bsky.social)
Reposted by Stefan Oehlers
There are only TEN DAYS left to submit your Oral Abstract or Workshop proposal for #SCZI2026. Join IZFS in Singapore for the first time, and present your cutting edge research to other #zebrafish Principal investigators! www.izfs.org/education/11...
11th Strategic Conference of Zebrafish Investigators | IZFS - International Zebrafish Society
Organizers | Registration | Abstracts | Program | Sponsorship | Workshops | Lodging | Financial Assistance
www.izfs.org
September 7, 2025 at 2:54 PM
There are only TEN DAYS left to submit your Oral Abstract or Workshop proposal for #SCZI2026. Join IZFS in Singapore for the first time, and present your cutting edge research to other #zebrafish Principal investigators! www.izfs.org/education/11...
Pro: you get to work alongside Caroline et al. in The Premier molecular biology institution in South East Asia. Con: we're moving into the same building and I will have access to your snack cabinet.
We are looking for a senior PI to join our team! Focus areas include, but are not restricted to the gut-brain axis, #neuroimmune interactions, and #neurodegeneration. Feel free to share and ping me for more details 🧠
www.nature.com/naturecareer...
#neurosciencejobs
www.nature.com/naturecareer...
#neurosciencejobs
Senior Principal Scientist (Neurometabolism) - Singapore (SG) job with A*STAR Institute of Molecular and Cell Biology | 12844045
A*STAR IMCB is seeking to hire outstanding Senior Principal Scientist (Assoc Prof/Prof) in neurometabolism / integrative cross-systems neuroscience
www.nature.com
September 4, 2025 at 2:39 PM
Pro: you get to work alongside Caroline et al. in The Premier molecular biology institution in South East Asia. Con: we're moving into the same building and I will have access to your snack cabinet.
Reposted by Stefan Oehlers
We are hiring! The Wattrus lab at MGH is seeking talented postdoc applicants to join our group and study differences in regeneration and wound healing across species using fish models. We are a fun group - come and join us! Fishy friends, please spread the word! #zebrafish #medaka #zebrafishjobs
September 2, 2025 at 4:00 PM
We are hiring! The Wattrus lab at MGH is seeking talented postdoc applicants to join our group and study differences in regeneration and wound healing across species using fish models. We are a fun group - come and join us! Fishy friends, please spread the word! #zebrafish #medaka #zebrafishjobs
Reposted by Stefan Oehlers
#SCZI2026 deadlines are quickly approaching! Oral Abstracts and Workshop proposals are due September 17, 2025, 11:59pm EDT. Be sure to register and submit before then to join us in Singapore January 14-17, 2026! www.izfs.org/education/11...
Registration | IZFS - International Zebrafish Society
www.izfs.org
September 3, 2025 at 5:02 PM
#SCZI2026 deadlines are quickly approaching! Oral Abstracts and Workshop proposals are due September 17, 2025, 11:59pm EDT. Be sure to register and submit before then to join us in Singapore January 14-17, 2026! www.izfs.org/education/11...
TB archeology paper! 300 year old mummies from a population with ~80% Mtb infection had a huge increase of ectopic rib growth out of their lower neck bones.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Unusually High Prevalence of Cervical Ribs in an 18th-Century Hungarian Town: The Impact of a Tuberculosis Epidemic.
Tuberculosis (TB) ravaged the Hungarian town of Vác in the 18th century. Nearly all of the young and middle-aged adults buried in the Dominican Church…
www.sciencedirect.com
September 2, 2025 at 5:52 AM
TB archeology paper! 300 year old mummies from a population with ~80% Mtb infection had a huge increase of ectopic rib growth out of their lower neck bones.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Stefan Oehlers
We are recruiting a postdoc to join our team and study neuroinflammation along the gut-brain axis. Please share it with anyone who may be interested, and do not hesitate to reach out if you have questions.
international.au.dk/about/profil...
international.au.dk/about/profil...
Postdoc position in Neuroinflammation - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - Neurobiology, Aarhus University
international.au.dk
September 1, 2025 at 1:47 PM
We are recruiting a postdoc to join our team and study neuroinflammation along the gut-brain axis. Please share it with anyone who may be interested, and do not hesitate to reach out if you have questions.
international.au.dk/about/profil...
international.au.dk/about/profil...