Nori Zolboot
@norjin.bsky.social
• Postdoc @scripps.edu Neuroscience
• MicroRNAs | Purkinje cells | RNA therapeutics
• What is sarcasm?
• PhD from Scripps Research ‘23
• BS from Nagoya University ‘17
• 🇲🇳->🇯🇵->🇺🇸 | 🔬🐱🧶🍫🎱🎬
• MicroRNAs | Purkinje cells | RNA therapeutics
• What is sarcasm?
• PhD from Scripps Research ‘23
• BS from Nagoya University ‘17
• 🇲🇳->🇯🇵->🇺🇸 | 🔬🐱🧶🍫🎱🎬
Reposted by Nori Zolboot
How fitting that the Preview of our Neuron paper was written by the one and only Roy Sillitoe. I saw him giving a talk at the 2018 Neural Development GRC, and his incredible data, storytelling, and enthusiasm convinced me to use Purkinje Cells as a model system.
www.cell.com/neuron/fullt...
www.cell.com/neuron/fullt...
Rooted in regulation: MicroRNAs as gardeners of the Purkinje cell dendritic arbor
Zolboot et al.1 developed tools to manipulate and map microRNA function in cerebellar
Purkinje cells with temporal precision, revealing key roles in dendritic development
and circuit connectivity. The...
www.cell.com
May 21, 2025 at 6:33 PM
How fitting that the Preview of our Neuron paper was written by the one and only Roy Sillitoe. I saw him giving a talk at the 2018 Neural Development GRC, and his incredible data, storytelling, and enthusiasm convinced me to use Purkinje Cells as a model system.
www.cell.com/neuron/fullt...
www.cell.com/neuron/fullt...
Reposted by Nori Zolboot
Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN
Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...
www.cnn.com
April 9, 2025 at 11:30 AM
Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
Reposted by Nori Zolboot
The Lipp Lab (@lippilab.bsky.social) has uncovered how microRNAs guide the development of Purkinje cells—rare neurons tied to movement and autism.
Published in Neuron, a @cellpress.bsky.social journal, the study maps how precise timing and gene regulation shape these cells’ identity and structure.
Published in Neuron, a @cellpress.bsky.social journal, the study maps how precise timing and gene regulation shape these cells’ identity and structure.
How microRNAs act as a “blueprint” for the developing brain
www.scripps.edu
April 3, 2025 at 6:24 PM
The Lipp Lab (@lippilab.bsky.social) has uncovered how microRNAs guide the development of Purkinje cells—rare neurons tied to movement and autism.
Published in Neuron, a @cellpress.bsky.social journal, the study maps how precise timing and gene regulation shape these cells’ identity and structure.
Published in Neuron, a @cellpress.bsky.social journal, the study maps how precise timing and gene regulation shape these cells’ identity and structure.
Reposted by Nori Zolboot
✨So happy to see part of my PhD work with @lippilab.bsky.social out today in @cp-neuron.bsky.social! ✨
We developed new tools to study microRNA-target networks with greater spatial and temporal resolution and found neuronal subtype- and developmental stage-specific roles:
We developed new tools to study microRNA-target networks with greater spatial and temporal resolution and found neuronal subtype- and developmental stage-specific roles:
MicroRNA mechanisms instructing Purkinje cell specification
Zolboot et al. introduce DD-T6B and SAP-seq, methods for investigating microRNA function
with enhanced spatiotemporal resolution, and identify Purkinje cell-specific microRNAs
and targets instructing ...
www.cell.com
April 2, 2025 at 7:27 PM
✨So happy to see part of my PhD work with @lippilab.bsky.social out today in @cp-neuron.bsky.social! ✨
We developed new tools to study microRNA-target networks with greater spatial and temporal resolution and found neuronal subtype- and developmental stage-specific roles:
We developed new tools to study microRNA-target networks with greater spatial and temporal resolution and found neuronal subtype- and developmental stage-specific roles:
Reposted by Nori Zolboot
How does gene regulation shape brain evolution? Our new preprint dives into this question in the context of mammalian cerebellum development! rb.gy/dbcxjz
Led by @ioansarr.bsky.social, @marisepp.bsky.social and @tyamadat.bsky.social, in collaboration with @steinaerts.bsky.social
Led by @ioansarr.bsky.social, @marisepp.bsky.social and @tyamadat.bsky.social, in collaboration with @steinaerts.bsky.social
March 16, 2025 at 10:31 AM
How does gene regulation shape brain evolution? Our new preprint dives into this question in the context of mammalian cerebellum development! rb.gy/dbcxjz
Led by @ioansarr.bsky.social, @marisepp.bsky.social and @tyamadat.bsky.social, in collaboration with @steinaerts.bsky.social
Led by @ioansarr.bsky.social, @marisepp.bsky.social and @tyamadat.bsky.social, in collaboration with @steinaerts.bsky.social
Reposted by Nori Zolboot
Stepwise molecular specification of excitatory synapse diversity onto cerebellar Purkinje cells
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Stepwise molecular specification of excitatory synapse diversity onto cerebellar Purkinje cells - Nature Neuroscience
Brain function requires the formation of diverse and specific synapses. The authors show that the molecular code specifying excitatory connectivity on Purkinje cells evolves in an input-specific manne...
www.nature.com
December 18, 2024 at 2:37 PM
Stepwise molecular specification of excitatory synapse diversity onto cerebellar Purkinje cells
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Using my first post as an excuse to share one of my favorite images of a sparsely labeled Purkinje cell. I have the fortune of studying these beautiful neurons - specifically how microRNAs contribute to their remarkable dendritic arborization.
🧠🔬👩🏻🔬
#cerebellum #neurons #purkinjecell
🧠🔬👩🏻🔬
#cerebellum #neurons #purkinjecell
November 21, 2024 at 7:49 PM
Using my first post as an excuse to share one of my favorite images of a sparsely labeled Purkinje cell. I have the fortune of studying these beautiful neurons - specifically how microRNAs contribute to their remarkable dendritic arborization.
🧠🔬👩🏻🔬
#cerebellum #neurons #purkinjecell
🧠🔬👩🏻🔬
#cerebellum #neurons #purkinjecell