For decades, the study of bacterial persistence has relied heavily on Escherichia coli as the primary model organism. Microbiologists have largely operated under the assumption that the mechanisms gov...

New research from the Neiditch lab at Rutgers New Jersey Medical School on the Vibrio cholerae CqsR receptor reveals how this pathogen monitors host-derived ethanolamine (and other related autoinducer...

The enzyme Pah1 is a central figure in the lipid metabolism of Saccharomyces cerevisiae, acting as a Mg2+-dependent phosphatidate (PA) phosphatase that converts PA into diacylglycerol. This catalytic ...

The pursuit of rapid, targeted protein evolution has been significantly advanced by systems like OrthoRep, which allows for high-rate in vivo hypermutation of specific genes in Saccharomyces cerevisia...

The persistent evolution of SARS-CoV-2, driven by the intrinsic infidelity of its RNA-dependent RNA polymerase, continues to pose challenges for global health management. The emergence of antigenicall...

We are sad to report that Richard Bartha, past president of Theobald Smith Society (1990-1991), passed away on August 11, 2025, at his home in Port Townsend, Washington.   He was ninety years old.  Ba...

Enteroviruses, including EV-D68, EV-A71, and Coxsackievirus B3 (CVB3), are a significant global health threat, causing a spectrum of diseases from mild respiratory illness to severe neurological compl...

Tick-borne co-infections are an escalating concern in endemic regions worldwide, notably in the United States, where the protozoan Babesia microti and the bacterium Borrelia burgdorferi are frequently...

Staphylococcus aureus remains a formidable human pathogen, being a leading cause of bacterial-induced death, with significant concerns regarding antibiotic resistance and the current lack of an effective vaccine. A major hurdle in combating S. aureus is that it is a human-adapted pathogen, expressing virulence factors specific to human cellular receptors. This specificity limits the utility of traditional mouse models, which often fail to accurately replicate human-specific host responses to inf

The SARS-CoV-2 pandemic may be behind us, but the virus continues its relentless evolution, posing ongoing challenges to public health. Research at the Center for Discovery & Innovation, led by Nadine...

Pediatric SARS-CoV-2 infection results in clinical presentations ranging from asymptomatic/mild infection to severe pulmonary COVID-19, to Multisystem Inflammatory Syndrome in Children (MIS-C), charac...

So why is the Royal College of Paediatrics and Child Health perpetuating this myth?

The persistent battle against Staphylococcus aureus (S. aureus), a leading cause of infectious disease-related illness and death worldwide, is continually complicated by its remarkable adaptability an...

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), continues to be a formidable global health threat, particularly in under-resourced areas where accurate and accessible diagnosis remains ...

For clinicians battling the persistent threat of fungal infections, Candida glabrata stands out as a formidable adversary, particularly due to its increasing resistance to frontline antifungal drugs l...

YouTube video by American Society for Microbiology

The Yellow Fever (YF) 17D vaccine, developed in the 1930s, stands as a triumph in vaccinology, recognized as one of the most potent and durable vaccines known. Despite its widespread success, having b...