Tiny but mighty: Rutgers study shows the 34-aa protein YoaI links phosphate, Mg²⁺, and osmotic stress pathways in E. coli. Small proteins = key cross-talk mediators in bacterial stress signaling. go.njmicrobe.org/1HDIM2 #Microbiology #SmallProteins #StressSignaling #Rutgers

ASM, ASBMB, ASCB & FASEB urge SCOTUS to block NIH from withholding canceled grants, warning of lasting harm to early-career scientists & U.S. science leadership. asm.org/press-releas.... #ResearchFunding #NIH #SciencePolicy

David Alland’s group at Rutgers Medical School identified the optimal tongue swab processing method for detecting Mycobacterium tuberculosis and rifampicin resistance using Cepheid’s Xpert MTB/RIF Ultra assay, as an alternative to sputum samples. journals.asm.org/doi/10.1128/...

The Herrera Lab at the Rutgers Global Health Institute along with Senegalese colleagues investigated the seroprevalence of Chikungunya virus and O'nyong-nyong virus in Senegal, West Africa, using samples from 470 non-febrile subjects. onlinelibrary.wiley.com/doi/10.1002/...

Zoe Narvaez successfully defended her PhD thesis in the Dept. of Entomology at Rutgers University. Her research focused on tick surveillance & pathogen prevalence in New Jersey, drawing from comprehensive field studies and molecular techniques. See more at: www.njmicrobe.org/post/congrat...

Researchers at Rutgers University Department of Food Science explored the effectiveness of plasma-activated mist, generated by combining dielectric barrier discharge plasma with nebulized liquid micro-droplets, in inactivating bacteria on fresh produce. www.sciencedirect.com/science/arti...

Thomas Dick’s lab at Hackensack Meridian found adding the FDA-approved durlobactam-sulbactam combination to β-lactam antibiotics imipenem and cefoxitin can significantly improve their potency and bactericidal activity against Mycobacterium abscessus. journals.asm.org/doi/10.1128/...

Rutgers found a new antibiotic, MGC-10, inhibiting bacterial protein synthesis by targeting the EF-Tu:tRNA. It is effective against a broad range of AMR Gram+ including MRSA. Although it's too toxic for systemic use and is proposed as a potential topical treatment. journals.asm.org/doi/full/10....

Barry Kreiswirth's lab at Hackensack Meridian examined the interplay between its CRISPR-Cas systems, anti-CRISPR proteins, and AMR genes that contribute to the global success of multi-drug resistant Klebsiella pneumoniae clone CG147. genomemedicine.biomedcentral.com/articles/10....

The Shaevitz Lab and Gitai Lab at Princeton explored the role of particle size and charge on the localization and dynamics of molecules within the crowded and polydisperse bacterial cytoplasm. www.pnas.org/doi/10.1073/...

The Mo LAB in Princeton continues to develop the HiTES approach on agar (instead of liquid media) to identify the molecules and their roles in initiating interactions between marine macroalgae and the prevalent Roseobacter group species closely associated with them. www.pnas.org/doi/10.1073/...

The Rajsbaum lab at Rutgers finds that host TRIM7 has antiviral effects against SARS-CoV-2 by ubiquitination of the viral M protein, immune response regulation, and IFN signaling modulation. Naturally occurring mutations in the M protein could impact pathogenicity. www.nature.com/articles/s41...

Rutgers' Don Schaffner and Stockton University's Cliff Baldwin present models for predicting the time to 3-log, 4-log, and 5-log reduction of Salmonella, E. coli O157:H7, and Listeria monocytogenes in commercially prepared salad dressings. www.sciencedirect.com/science/arti...

Jamie Calwell, High Meadows Environmental Institute at Princeton developed a modeling approach to assess Zika virus (ZIKV) transmission risk across Africa. The most populous African cities could become suitable for ZIKV transmission by the end of the century. www.thelancet.com/journals/lan...

Pfizer was awarded the National Medal of Technology for developing the Pfizer-BioNTech COVID-19 Vaccine. Theobald Smith Society member Annaliesa Anderson, SVP and Head, Pfizer Vaccine R&D, represented Pfizer at the ceremony. Here's what she said about the award: www.linkedin.com/feed/update/...

Theobald Smith Society Lifetime member and 2003 Waksman Honorary Lecturer Bonnie Bassler has been awarded The National Medal of Science. Princeton’s Bonnie Bassler was instrumental in founding a new branch of science centered on quorum sensing. nationalmedals.org/stories/the-...

Improved Broad Spectrum Antifungal Drug Synergies with Cryptomycin, a Cdc50-Inspired Antifungal Peptide
Robert J. Tancer, Siddhi Pawar, Yina Wang, Cristina R. Ventura, Gregory Wiedman, and Chaoyang Xue
ACS Infectious Diseases 2024 10 (11), 3973-3993
pubs.acs.org/doi/10.1021/...