Nicolas Pégard
nicopegard.bsky.social
Nicolas Pégard
@nicopegard.bsky.social
Associate Prof. of Applied Physical Sciences at UNC Chapel Hill. Engineer at heart, accidental neuroscientist, faculty by day, tech dev by night. Allergic to fake science, thoughts my own.
Reposted by Nicolas Pégard
TT faculty job opening in #Neuroscience!
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961
Brandeis University, Biology Department
Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US
academicjobsonline.org
October 22, 2025 at 11:28 PM
this is just beautiful !
Nat. Photonics🔬 Meet 3I-SIM!
Instead of stripes, we use 3-beam to generate 2D hex pattern for simultaneous 2D SIM modulation, with >100,000 frames, 13 h neuronal cell movies, ER–lipid-droplet kiss-n-run and millisecond tango. All hard&software open.
doi.org/10.1038/s415... @pku1898.bsky.social
Triangle-beam interference structured illumination microscopy - Nature Photonics
Triangle-beam interference structured illumination microscopy leverages radially polarized beams to generate two-dimensional lattice illumination patterns. The technique enables a temporal resolution ...
doi.org
August 16, 2025 at 12:36 PM
Reposted by Nicolas Pégard
Eight #BYI, #AOBPostdoc and #BSP awardees will present their research during Plenary Session I, starting now in Regency ABC. #BeckmanSymposium #plenary #technicaltalks #presentation #research #agenda #conference #meeting #BeckmanScholars
August 1, 2025 at 8:14 PM
Reposted by Nicolas Pégard
Keynote Speaker Dr. Chad Mirkin presents during the morning session of Day 2 at the 2025 #BeckmanSymposium
August 1, 2025 at 6:40 PM
Check out our lab, featured in a video produced by @uncchapelhill.bsky.social for @beckman-foundation.bsky.social
2021 BYI Nicolas Pégard
YouTube video by Beckman Foundation
www.youtube.com
August 1, 2025 at 12:12 AM
Reposted by Nicolas Pégard
Lonni Besançon, a data-visualization researcher, spoke with Nature Careers about his work as a research-integrity sleuth that started during the COVID-19 pandemic and facing online abuse, threats and legal challenges because of it. #Academicsky 🧪
The COVID-19 pandemic transformed this scientist into a research-integrity sleuth
Nature Careers
go.nature.com
July 26, 2025 at 10:42 PM
Reposted by Nicolas Pégard
NEW: NSF will be kicked out of their building. Announcement will be made tomorrow by HUD Sec. and Governor of VA. HUD will take over the NSF building over the next two years.

NSF staffer: "There is no planning for NSF, no identified future location, appropriation for a new building or a move."
June 24, 2025 at 10:20 PM
Reposted by Nicolas Pégard
📢BREAKING: Just left the courthouse for our NIH grant termination case

Judge ruled terminations are “VOID & ILLEGAL”

As a plaintiff, I felt a wave of relief & hope; he acknowledged the discrimination & harm

Closed by asking, ‘Have we fallen so low? Have we no shame?’
June 16, 2025 at 9:26 PM
Reposted by Nicolas Pégard
Compressive microscopy enables new experimental capabilities to monitor brain activity at a sampling speed that outpaces camera frame rates! 💡📸🧠

Read the research from @uncchapelhill.bsky.social, Duke Univ., & @hhmi.org‬ in #Neurophotonics: www.spiedigitallibra...

@nicopegard.bsky.social
June 6, 2025 at 11:15 PM
Reposted by Nicolas Pégard
Plug for my lab’s open source commutator designed for compatibility with electrical I/O, an accessible through-hole for non-electrical tethers, and low-noise active rotation. I have gotten great performance out of it and recommend it to anyone needing a commutator!

www.eneuro.org/content/eneu...
www.eneuro.org
May 9, 2025 at 2:01 PM
Microscopy produces images, but images are not always what we want. With collaborators at Duke and HHMI, we show that optical tricks can transfer more information from the sample to the camera, and then, algorithms retrieve publishable data. www.spiedigitallibrary.org/journals/neu...
Compressive streak microscopy for fast sampling of fluorescent reporters of neural activity
SignificanceIn vivo one-photon fluorescence imaging of calcium and voltage indicators expressed in neurons enables noninvasive recordings of neural activity with submillisecond precision. However, data acquisition speed is limited by the frame rate of cameras.AimWe developed a compressive streak fluorescence microscope to record fluorescence in individual neurons at high speeds (≥200 frames per second) exceeding the nominal frame rate of the camera by trading off spatial pixels for temporal resolution.ApproachOur microscope leverages a digital micromirror device for targeted illumination, a galvo mirror for temporal scanning, and a ridge regression algorithm for fast computational reconstruction of fluorescence traces with high temporal resolution.ResultsIn simulations, the ridge regression algorithm reconstructs traces of high temporal resolution with limited signal loss. Validation experiments with fluorescent beads and experiments in larval zebrafish demonstrate accurate reconstruction with a data compression ratio of 10 and accurate recordings of neural activity with 200- to 400-Hz sampling speeds.ConclusionsOur compressive microscopy enables new experimental capabilities to monitor activity at a sampling speed that outpaces the nominal frame rate of the camera.
www.spiedigitallibrary.org
May 23, 2025 at 1:58 PM
Reposted by Nicolas Pégard
I am a former incarcerated firefighter. I served in a California fire camp from 2009 to 2012.

Misinformation is afire on the internet, so here are facts about the prison firefighter program, all in one place.

A thread.
January 15, 2025 at 1:20 AM
Reposted by Nicolas Pégard
Progress on the quest for a red mStayGold!
Just out: mScarlet3-S2, a new photostable red FP derived from mScarlet3: www.researchsquare.com/article/rs-5...
December 25, 2024 at 8:45 AM
What incentives do you have as faculty to set high standards and not give a free A to all your students ? i just saw one of my colleagues -who is a much better teacher than me- get trashed with nonsensical claims on ratemyprofessor, in a class that I taught too, probably by students who got a B.
December 22, 2024 at 1:43 PM
Looking at the last 10 emails I received from students taking my class I can see similar GPT-like phrasing across 5 of them. LPT, a short, personal email, even filled with your human typos is far more appreciated than any of the LLM diarrhea you force me to read.
December 10, 2024 at 2:28 AM
science.xyz/news/biohybr... I am looking forward what this cool team will do next !
Biohybrid neural interfaces: an old idea enabling a completely new space of possibilities | Science Corporation
Science Corporation is a clinical-stage medical technology company.
science.xyz
November 30, 2024 at 12:40 PM