Sarah Moyon
@neurosarah.bsky.social
Neuroscientist @inp-marseille.bsky.social, Myelin & OPC enthusiast with an Aging twist, Chaire d’Excellence #Amidex #AMU, moyonlab.com, She/her
Pinned
Sarah Moyon
@neurosarah.bsky.social
· Oct 1
Matinée NeuroMAP – Visite de laboratoire | NeuroMarseille
neuro-marseille.org
NeuroMAP @neuromarseille.bsky.social @univ-amu.fr organise une visite de laboratoire sur le campus de la Timone le 14 Novembre ! Venez rencontrer nos chercheurs 👩🏻🔬🧑🏽🔬
neuro-marseille.org/events/journ...
neuro-marseille.org/events/journ...
Reposted by Sarah Moyon
Apolipoprotein ε4 exacerbates white matter impairment in a mouse model of Aβ amyloidosis by decreasing actively myelinating oligodendrocytes - Al‐Amin - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Apolipoprotein ε4 exacerbates white matter impairment in a mouse model of Aβ amyloidosis by decreasing actively myelinating oligodendrocytes
INTRODUCTION
The ε4 allele of the apolipoprotein E (APOE) gene is a risk factor for the development of Alzheimer's disease (AD). APOE4 isoform is associated with increased white matter lesions in hu.....
alz-journals.onlinelibrary.wiley.com
November 11, 2025 at 4:37 AM
Apolipoprotein ε4 exacerbates white matter impairment in a mouse model of Aβ amyloidosis by decreasing actively myelinating oligodendrocytes - Al‐Amin - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Sarah Moyon
Interesting study from the ppl @solvingforsci.bsky.social. Very much in line with our earlier findings with @preprintclub.bsky.social (www.biorxiv.org/content/10.1...) :
1/ Reviewers can distinguish quality and impact (+novelty in our model)
2/ Trainees want to review
3/ Authors love the experience
1/ Reviewers can distinguish quality and impact (+novelty in our model)
2/ Trainees want to review
3/ Authors love the experience
November 11, 2025 at 4:39 PM
Interesting study from the ppl @solvingforsci.bsky.social. Very much in line with our earlier findings with @preprintclub.bsky.social (www.biorxiv.org/content/10.1...) :
1/ Reviewers can distinguish quality and impact (+novelty in our model)
2/ Trainees want to review
3/ Authors love the experience
1/ Reviewers can distinguish quality and impact (+novelty in our model)
2/ Trainees want to review
3/ Authors love the experience
🤩
We got the cover 🎉🎉 🎉 ! Beautiful artwork from the talented Carole Marchese, PhD student in my lab.
November 4, 2025 at 9:38 PM
🤩
Reposted by Sarah Moyon
Link to new study in Science:
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.
🧪🧬
www.science.org/doi/10.1126/...
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.
🧪🧬
www.science.org/doi/10.1126/...
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging
Efficient DNA repair might make possible the longevity of naked mole-rats. However, whether they have distinctive mechanisms to optimize functions of DNA repair suppressors is unclear. We find that na...
www.science.org
October 12, 2025 at 7:37 AM
Link to new study in Science:
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.
🧪🧬
www.science.org/doi/10.1126/...
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.
🧪🧬
www.science.org/doi/10.1126/...
Reposted by Sarah Moyon
NSAIDs are known to alleviate pain by reducing inflammation. A study in Nature Communications shows that selective inhibition of the prostaglandin E2 receptor in Schwann cells eliminates pain without disrupting the protective and healing functions of inflammation. #medsky 🧪
Targeting prostaglandin E2 receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation - Nature Communications
Non-steroidal anti-inflammatory drugs (NSAIDs) are known to alleviate pain by reducing inflammation. To the contrary, here, the authors show that selective inhibition of the prostaglandin E2 receptor (EP2) in Schwann cells eliminates pain without disrupting the protective and healing functions of inflammation.
go.nature.com
October 13, 2025 at 1:03 AM
NSAIDs are known to alleviate pain by reducing inflammation. A study in Nature Communications shows that selective inhibition of the prostaglandin E2 receptor in Schwann cells eliminates pain without disrupting the protective and healing functions of inflammation. #medsky 🧪
Reposted by Sarah Moyon
The GCC is planning on-site childcare for the upcoming Glial Cell Club meeting (Nov 17–20, 2026, Lazaret site).
Please fill out our short survey to help us secure support and organize the service: forms.gle/GyLXfS6fhnVs...
Input is welcome even if you won’t use childcare.
Please fill out our short survey to help us secure support and organize the service: forms.gle/GyLXfS6fhnVs...
Input is welcome even if you won’t use childcare.
Daycare at Glial Cell Club next meeting (November 17-20, 2026)
The GCC organizing committee is committed to supporting our community by helping reconcile professional and personal lives, especially for parents of young children. We are therefore working to provid...
forms.gle
September 30, 2025 at 11:27 AM
The GCC is planning on-site childcare for the upcoming Glial Cell Club meeting (Nov 17–20, 2026, Lazaret site).
Please fill out our short survey to help us secure support and organize the service: forms.gle/GyLXfS6fhnVs...
Input is welcome even if you won’t use childcare.
Please fill out our short survey to help us secure support and organize the service: forms.gle/GyLXfS6fhnVs...
Input is welcome even if you won’t use childcare.
NeuroMAP @neuromarseille.bsky.social @univ-amu.fr organise une visite de laboratoire sur le campus de la Timone le 14 Novembre ! Venez rencontrer nos chercheurs 👩🏻🔬🧑🏽🔬
neuro-marseille.org/events/journ...
neuro-marseille.org/events/journ...
Matinée NeuroMAP – Visite de laboratoire | NeuroMarseille
neuro-marseille.org
October 1, 2025 at 9:49 AM
NeuroMAP @neuromarseille.bsky.social @univ-amu.fr organise une visite de laboratoire sur le campus de la Timone le 14 Novembre ! Venez rencontrer nos chercheurs 👩🏻🔬🧑🏽🔬
neuro-marseille.org/events/journ...
neuro-marseille.org/events/journ...
Reposted by Sarah Moyon
Did you know that facial expressions reveal more than meets the eye? 🤯
Our new study shows that even a mouse's face 🐭 can reflect hidden neural computations🧠. Turns out, facial expressions are more than just emotions!
We're so excited to see this paper out @natneuro.nature.com 🎉
🔗: rdcu.be/eIQzO
Our new study shows that even a mouse's face 🐭 can reflect hidden neural computations🧠. Turns out, facial expressions are more than just emotions!
We're so excited to see this paper out @natneuro.nature.com 🎉
🔗: rdcu.be/eIQzO
Facial expressions in mice reveal latent cognitive variables and their neural correlates
Nature Neuroscience - The face reveals more than just emotion. Cazettes, Reato and colleagues show that subtle facial movements reveal hidden cognitive states, reflecting the brain’s ongoing...
rdcu.be
September 30, 2025 at 11:30 AM
Did you know that facial expressions reveal more than meets the eye? 🤯
Our new study shows that even a mouse's face 🐭 can reflect hidden neural computations🧠. Turns out, facial expressions are more than just emotions!
We're so excited to see this paper out @natneuro.nature.com 🎉
🔗: rdcu.be/eIQzO
Our new study shows that even a mouse's face 🐭 can reflect hidden neural computations🧠. Turns out, facial expressions are more than just emotions!
We're so excited to see this paper out @natneuro.nature.com 🎉
🔗: rdcu.be/eIQzO
Reposted by Sarah Moyon
How do your #linguistic, #economic & #gender backgrounds impact your #scientific productivity? @tatsuya-amano.bsky.social & co reveal that being a woman, a non-native English speaker, and from a low-income country is associated with a 70% reduction in productivity @plosbiology.org 🧪 plos.io/4n3RLRQ
September 19, 2025 at 1:12 PM
How do your #linguistic, #economic & #gender backgrounds impact your #scientific productivity? @tatsuya-amano.bsky.social & co reveal that being a woman, a non-native English speaker, and from a low-income country is associated with a 70% reduction in productivity @plosbiology.org 🧪 plos.io/4n3RLRQ
Reposted by Sarah Moyon
✨ Post-doc opportunity in axon biology, funded by #ATIP-Avenir!
👀 We are looking for an enthusiastic post-doc to join our team at @ibdm.bsky.social to explore translation dynamics in axon regrowth, using live imaging approaches.
Apply at: emploi.cnrs.fr/Offres/CDD/U...
Thank you for sharing! 👋 🙏
👀 We are looking for an enthusiastic post-doc to join our team at @ibdm.bsky.social to explore translation dynamics in axon regrowth, using live imaging approaches.
Apply at: emploi.cnrs.fr/Offres/CDD/U...
Thank you for sharing! 👋 🙏
Portail Emploi CNRS - Offre d'emploi - Post-doctoral researcher in axon biology (M/F)
emploi.cnrs.fr
September 11, 2025 at 12:24 PM
✨ Post-doc opportunity in axon biology, funded by #ATIP-Avenir!
👀 We are looking for an enthusiastic post-doc to join our team at @ibdm.bsky.social to explore translation dynamics in axon regrowth, using live imaging approaches.
Apply at: emploi.cnrs.fr/Offres/CDD/U...
Thank you for sharing! 👋 🙏
👀 We are looking for an enthusiastic post-doc to join our team at @ibdm.bsky.social to explore translation dynamics in axon regrowth, using live imaging approaches.
Apply at: emploi.cnrs.fr/Offres/CDD/U...
Thank you for sharing! 👋 🙏
Reposted by Sarah Moyon
America’s cancer research system is under threat in one of its most productive moments. www.nytimes.com/2025/09/14/m...
Trump Is Shutting Down the War On Cancer
www.nytimes.com
September 14, 2025 at 4:12 PM
America’s cancer research system is under threat in one of its most productive moments. www.nytimes.com/2025/09/14/m...
Reposted by Sarah Moyon
Latest from us: we detail the protocol we use to generate mRNA-LNPs and to study immune response in preclinical setting.
link.springer.com/protocol/10....
link.springer.com/protocol/10....
Generation of Lipid Nanoparticle mRNA Vaccines and Evaluation of Antigen-Specific CD8+ T-Cell Responses
mRNA vaccines have revolutionized vaccine development against infectious diseases, as demonstrated by the rapid creation and deployment of vaccines for SARS-CoV-2. In this chapter, we present a protoc...
link.springer.com
September 2, 2025 at 11:01 PM
Latest from us: we detail the protocol we use to generate mRNA-LNPs and to study immune response in preclinical setting.
link.springer.com/protocol/10....
link.springer.com/protocol/10....
Reposted by Sarah Moyon
Now online! Transient gene melting governs the timing of oligodendrocyte maturation
Transient gene melting governs the timing of oligodendrocyte maturation
Oligodendrocyte maturation is governed by an SOX6-dependent gene-melted chromatin state at multiple immaturity loci. Reducing SOX6 accelerates maturation, offering a potential strategy to regenerate myelin in diseases like multiple sclerosis.
dlvr.it
August 25, 2025 at 2:59 PM
Now online! Transient gene melting governs the timing of oligodendrocyte maturation
Reposted by Sarah Moyon
Reposted by Sarah Moyon
Review now out in @npp-journal.bsky.social!
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq
Epigenetic regulation of brain development, plasticity, and response to early-life stress
Neuropsychopharmacology - Epigenetic regulation of brain development, plasticity, and response to early-life stress
rdcu.be
August 6, 2025 at 3:38 PM
Review now out in @npp-journal.bsky.social!
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq
Reposted by Sarah Moyon
📢 Call for Social Media Ambassadors!
Help us grow the #GLIA community online & get a free registration for GLIA 2027 in Bologna!
We're looking for 5 voices from the field – content, updates, community vibes.
⏰ Apply by Aug 26!
👉 secretariat@networkglia.eu
Help us grow the #GLIA community online & get a free registration for GLIA 2027 in Bologna!
We're looking for 5 voices from the field – content, updates, community vibes.
⏰ Apply by Aug 26!
👉 secretariat@networkglia.eu
August 4, 2025 at 9:33 AM
📢 Call for Social Media Ambassadors!
Help us grow the #GLIA community online & get a free registration for GLIA 2027 in Bologna!
We're looking for 5 voices from the field – content, updates, community vibes.
⏰ Apply by Aug 26!
👉 secretariat@networkglia.eu
Help us grow the #GLIA community online & get a free registration for GLIA 2027 in Bologna!
We're looking for 5 voices from the field – content, updates, community vibes.
⏰ Apply by Aug 26!
👉 secretariat@networkglia.eu
Reposted by Sarah Moyon
🧠 Opportunity for a post-doctoral position on human neurobiology, funded by the @erc.europa.eu!
🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you!
🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...
🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you!
🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...
Portail Emploi CNRS - Offre d'emploi - Postdoctoral researcher in human neurobiology (M/F)
emploi.cnrs.fr
July 30, 2025 at 8:26 AM
🧠 Opportunity for a post-doctoral position on human neurobiology, funded by the @erc.europa.eu!
🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you!
🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...
🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you!
🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...
Reposted by Sarah Moyon
Meet the minds behind the scenes!
Get to know our amazing organizers and stay in the loop with all things Warsaw Glia Community Symposium.
Don't forget to register on the official event page!
sites.google.com/uw.edu.pl/wa...
#GLIA #WGC
@szewczyklukasz.bsky.social
Get to know our amazing organizers and stay in the loop with all things Warsaw Glia Community Symposium.
Don't forget to register on the official event page!
sites.google.com/uw.edu.pl/wa...
#GLIA #WGC
@szewczyklukasz.bsky.social
July 19, 2025 at 11:14 AM
Meet the minds behind the scenes!
Get to know our amazing organizers and stay in the loop with all things Warsaw Glia Community Symposium.
Don't forget to register on the official event page!
sites.google.com/uw.edu.pl/wa...
#GLIA #WGC
@szewczyklukasz.bsky.social
Get to know our amazing organizers and stay in the loop with all things Warsaw Glia Community Symposium.
Don't forget to register on the official event page!
sites.google.com/uw.edu.pl/wa...
#GLIA #WGC
@szewczyklukasz.bsky.social
Reposted by Sarah Moyon
We had fun assembling images and describing approaches for imaging oligodendrocytes and myelin in vivo, in organotypic slices, and in fixed tissues. This work started in the lab of @jgrutzendler.bsky.social over 10 years ago and continues to keep us busy.
www.nature.com/articles/s44...
www.nature.com/articles/s44...
July 18, 2025 at 6:15 PM
We had fun assembling images and describing approaches for imaging oligodendrocytes and myelin in vivo, in organotypic slices, and in fixed tissues. This work started in the lab of @jgrutzendler.bsky.social over 10 years ago and continues to keep us busy.
www.nature.com/articles/s44...
www.nature.com/articles/s44...
Reposted by Sarah Moyon
What a week in Marseille! 🇫🇷 #GLIA2025 is done, but the buzz stays. We’re already gearing up for #GLIA2027! First step: forming the Programme Committee with a democratic vote by past delegates. Fun fact: GLIA’s even in MarsiGLIA (Italian for Marseille)!
#GliologistsTogether
#GliologistsTogether
July 15, 2025 at 9:27 AM
What a week in Marseille! 🇫🇷 #GLIA2025 is done, but the buzz stays. We’re already gearing up for #GLIA2027! First step: forming the Programme Committee with a democratic vote by past delegates. Fun fact: GLIA’s even in MarsiGLIA (Italian for Marseille)!
#GliologistsTogether
#GliologistsTogether
Reposted by Sarah Moyon
Network Glia!
The French Glial Cell Club is present @Glia2025 as @italianglianetwork.bsky.social
@ukglia.bsky.social
@gliameeting.bsky.social
@gliameeting.bsky.social
@atglianet.bsky.social
The French Glial Cell Club is present @Glia2025 as @italianglianetwork.bsky.social
@ukglia.bsky.social
@gliameeting.bsky.social
@gliameeting.bsky.social
@atglianet.bsky.social
July 8, 2025 at 1:56 PM
Network Glia!
The French Glial Cell Club is present @Glia2025 as @italianglianetwork.bsky.social
@ukglia.bsky.social
@gliameeting.bsky.social
@gliameeting.bsky.social
@atglianet.bsky.social
The French Glial Cell Club is present @Glia2025 as @italianglianetwork.bsky.social
@ukglia.bsky.social
@gliameeting.bsky.social
@gliameeting.bsky.social
@atglianet.bsky.social
Reposted by Sarah Moyon
On now, last session of #Glia2025, and last presenter from the lab.
S26 | Exploring glial diversity using single cell and spatial genomics
@mrodea.bsky.social
10:00 S26-01 Multi-omic definition of astrocyte diversity in the healthy and inflamed brain
S26 | Exploring glial diversity using single cell and spatial genomics
@mrodea.bsky.social
10:00 S26-01 Multi-omic definition of astrocyte diversity in the healthy and inflamed brain
July 11, 2025 at 8:11 AM
On now, last session of #Glia2025, and last presenter from the lab.
S26 | Exploring glial diversity using single cell and spatial genomics
@mrodea.bsky.social
10:00 S26-01 Multi-omic definition of astrocyte diversity in the healthy and inflamed brain
S26 | Exploring glial diversity using single cell and spatial genomics
@mrodea.bsky.social
10:00 S26-01 Multi-omic definition of astrocyte diversity in the healthy and inflamed brain
Reposted by Sarah Moyon
#GLIA2025 is in full swing!
We’re halfway through an exciting week full of energy, ideas, and exchange.
Highlights so far:
🎓 Stipend Award Session
🧠 Poster Sessions
🤝 Welcome Reception
Let’s keep the momentum going!
#GliologistsTogether
We’re halfway through an exciting week full of energy, ideas, and exchange.
Highlights so far:
🎓 Stipend Award Session
🧠 Poster Sessions
🤝 Welcome Reception
Let’s keep the momentum going!
#GliologistsTogether
July 10, 2025 at 3:32 PM
#GLIA2025 is in full swing!
We’re halfway through an exciting week full of energy, ideas, and exchange.
Highlights so far:
🎓 Stipend Award Session
🧠 Poster Sessions
🤝 Welcome Reception
Let’s keep the momentum going!
#GliologistsTogether
We’re halfway through an exciting week full of energy, ideas, and exchange.
Highlights so far:
🎓 Stipend Award Session
🧠 Poster Sessions
🤝 Welcome Reception
Let’s keep the momentum going!
#GliologistsTogether
Reposted by Sarah Moyon
#glia2025 Interested in metabolism+ (re)myelination? Today Luna Mora presents her results on the effect of keto diet on remyelination with age, poster T20-021b. Tomorrow, our recent preprint on the role of MCT2 in myelin maintenance(doi.org/10.1101/2025.0…) poster T06-031c
July 9, 2025 at 9:38 AM
#glia2025 Interested in metabolism+ (re)myelination? Today Luna Mora presents her results on the effect of keto diet on remyelination with age, poster T20-021b. Tomorrow, our recent preprint on the role of MCT2 in myelin maintenance(doi.org/10.1101/2025.0…) poster T06-031c