Reposted by Shweta Shah
These are not FDA approved yet - this trial + VISIONARY for Sibeprenlimab will lead to approval soon
Approved =
Nefecon
Atrasentan
Sparsentan
Iptacopan
(I think)
#Nephjc
Approved =
Nefecon
Atrasentan
Sparsentan
Iptacopan
(I think)
#Nephjc
November 19, 2025 at 2:20 AM
These are not FDA approved yet - this trial + VISIONARY for Sibeprenlimab will lead to approval soon
Approved =
Nefecon
Atrasentan
Sparsentan
Iptacopan
(I think)
#Nephjc
Approved =
Nefecon
Atrasentan
Sparsentan
Iptacopan
(I think)
#Nephjc
Reposted by Shweta Shah
November 19, 2025 at 5:21 PM
Reposted by Shweta Shah
Late breakers that included children:
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
November 8, 2025 at 8:27 PM
Late breakers that included children:
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
Peds nephrons at #ASN2025 #KidneyWk , participate in @aspneph.bsky.social scavenger hunt and win prizes!
Download ASPNGo App!!
@nefronica-2rair.bsky.social @coleaugust.bsky.social
Download ASPNGo App!!
@nefronica-2rair.bsky.social @coleaugust.bsky.social
November 5, 2025 at 1:02 PM
Peds nephrons at #ASN2025 #KidneyWk , participate in @aspneph.bsky.social scavenger hunt and win prizes!
Download ASPNGo App!!
@nefronica-2rair.bsky.social @coleaugust.bsky.social
Download ASPNGo App!!
@nefronica-2rair.bsky.social @coleaugust.bsky.social
Reposted by Shweta Shah
Clinical importance of prediction tools: 🔬
The prediction tool was developed with the data from 4000 people in multinational and multiracial cohorts and can be generalized to all.
Do you routinely use prediction tools with IgAN patients? #NephJC
The prediction tool was developed with the data from 4000 people in multinational and multiracial cohorts and can be generalized to all.
Do you routinely use prediction tools with IgAN patients? #NephJC
October 29, 2025 at 1:15 AM
Clinical importance of prediction tools: 🔬
The prediction tool was developed with the data from 4000 people in multinational and multiracial cohorts and can be generalized to all.
Do you routinely use prediction tools with IgAN patients? #NephJC
The prediction tool was developed with the data from 4000 people in multinational and multiracial cohorts and can be generalized to all.
Do you routinely use prediction tools with IgAN patients? #NephJC
Reposted by Shweta Shah
Treatment in children: 👶💉
Management is based on RAS blockade, salt restriction, and blood pressure control. Glucocorticoids are used in those with persistent proteinuria or high-risk features, sometimes combined with cyclophosphamide in severe cases.
#NephJC
Management is based on RAS blockade, salt restriction, and blood pressure control. Glucocorticoids are used in those with persistent proteinuria or high-risk features, sometimes combined with cyclophosphamide in severe cases.
#NephJC
October 29, 2025 at 1:39 AM
Treatment in children: 👶💉
Management is based on RAS blockade, salt restriction, and blood pressure control. Glucocorticoids are used in those with persistent proteinuria or high-risk features, sometimes combined with cyclophosphamide in severe cases.
#NephJC
Management is based on RAS blockade, salt restriction, and blood pressure control. Glucocorticoids are used in those with persistent proteinuria or high-risk features, sometimes combined with cyclophosphamide in severe cases.
#NephJC
Reposted by Shweta Shah
🤔 How often is end-stage kidney disease in patients with MCD/ FSGS? #NephSky #MedSky
@brianrifkin.bsky.social dissected the conclusions from the RaDar study in this #NephJCshorts
*the original article from @asnpublications.bsky.social
www.nephjc.com/news/nephjc-...
@brianrifkin.bsky.social dissected the conclusions from the RaDar study in this #NephJCshorts
*the original article from @asnpublications.bsky.social
www.nephjc.com/news/nephjc-...
NephJC Shorts: MCD and FSGS Outcomes — NephJC
A NephJC Shorts discussion of the long term data on kidney failure in FSGS and MCD
www.nephjc.com
September 6, 2025 at 5:00 PM
🤔 How often is end-stage kidney disease in patients with MCD/ FSGS? #NephSky #MedSky
@brianrifkin.bsky.social dissected the conclusions from the RaDar study in this #NephJCshorts
*the original article from @asnpublications.bsky.social
www.nephjc.com/news/nephjc-...
@brianrifkin.bsky.social dissected the conclusions from the RaDar study in this #NephJCshorts
*the original article from @asnpublications.bsky.social
www.nephjc.com/news/nephjc-...
Reposted by Shweta Shah
Everything said and done - although eGFR diff may signal ominous outcomes - practically speaking following one eGFR over time and seeing the eGFR fall predicts outcomes better than anything else ! And that’s what would be feasible across economies ! #NephJC
July 23, 2025 at 1:54 AM
Everything said and done - although eGFR diff may signal ominous outcomes - practically speaking following one eGFR over time and seeing the eGFR fall predicts outcomes better than anything else ! And that’s what would be feasible across economies ! #NephJC
Reposted by Shweta Shah
The #NephJC editorial team knows that plenty of papers deserve attention between our bi-monthly, full-length discussions
✨Enter #NephJCShorts - quick hits with a critical eye 🦅 on high-impact reads
www.nephjc.com/news/nephjc-...
#MedSky #NephSky
✨Enter #NephJCShorts - quick hits with a critical eye 🦅 on high-impact reads
www.nephjc.com/news/nephjc-...
#MedSky #NephSky
Introducing NephJC Shorts — NephJC
In just over a decade of critical appraisal on NephJC, we have done several experiments. Some of them have worked out phenomenally well, such as the Freely Filtered podcast. Others were not ready for ...
www.nephjc.com
July 2, 2025 at 1:27 PM
The #NephJC editorial team knows that plenty of papers deserve attention between our bi-monthly, full-length discussions
✨Enter #NephJCShorts - quick hits with a critical eye 🦅 on high-impact reads
www.nephjc.com/news/nephjc-...
#MedSky #NephSky
✨Enter #NephJCShorts - quick hits with a critical eye 🦅 on high-impact reads
www.nephjc.com/news/nephjc-...
#MedSky #NephSky
Reposted by Shweta Shah
From Rivka Galchen’s article in @newyorker.com:
“The kidney, a tremendously under-celebrated organ, basically does four-dimensional sudoku with ions.”
And that’s how I’m going to explain it from now on.
“The kidney, a tremendously under-celebrated organ, basically does four-dimensional sudoku with ions.”
And that’s how I’m going to explain it from now on.
June 22, 2025 at 10:06 PM
From Rivka Galchen’s article in @newyorker.com:
“The kidney, a tremendously under-celebrated organ, basically does four-dimensional sudoku with ions.”
And that’s how I’m going to explain it from now on.
“The kidney, a tremendously under-celebrated organ, basically does four-dimensional sudoku with ions.”
And that’s how I’m going to explain it from now on.
Reposted by Shweta Shah
I do the same with any agent. Treat for 2 years then try off. If relapse, then another 2 years. #NephJc I don’t think there’s great data. Just seems a good balance of risk.
June 11, 2025 at 2:13 AM
I do the same with any agent. Treat for 2 years then try off. If relapse, then another 2 years. #NephJc I don’t think there’s great data. Just seems a good balance of risk.
Reposted by Shweta Shah
Congrats to all the @asnkidney.bsky.social lifetime and mid-career awardees!
@ksusztak.bsky.social @genetickidneydoc.bsky.social @shinamenon.bsky.social @michellejtx.bsky.social and everyone else!
@ksusztak.bsky.social @genetickidneydoc.bsky.social @shinamenon.bsky.social @michellejtx.bsky.social and everyone else!
June 3, 2025 at 7:13 PM
Congrats to all the @asnkidney.bsky.social lifetime and mid-career awardees!
@ksusztak.bsky.social @genetickidneydoc.bsky.social @shinamenon.bsky.social @michellejtx.bsky.social and everyone else!
@ksusztak.bsky.social @genetickidneydoc.bsky.social @shinamenon.bsky.social @michellejtx.bsky.social and everyone else!
Would make sense to check VWF otherwise hard to prove anything unless they compare with their previous institutional cohort
# NephJC
# NephJC
📊 Check out the study procedure infographic below!
A side-by-side look at both RCTs — design, dose, and more.
Great work by @nephroseeker.medsky.social 👏
#NephJC
A side-by-side look at both RCTs — design, dose, and more.
Great work by @nephroseeker.medsky.social 👏
#NephJC
May 14, 2025 at 1:29 AM
Would make sense to check VWF otherwise hard to prove anything unless they compare with their previous institutional cohort
# NephJC
# NephJC
Reposted by Shweta Shah
T0c
So how does DDAVP skip the bleeding drama? 🩸
🧬 Desmopressin → triggers cAMP → exocytosis of vWF & FVIII from endothelium
➡️ Boosts platelet adhesion in uremic dysfunction
⏱️ Onset: 30–90 min ⏳ Duration: 4–8 h
#NephJC
So how does DDAVP skip the bleeding drama? 🩸
🧬 Desmopressin → triggers cAMP → exocytosis of vWF & FVIII from endothelium
➡️ Boosts platelet adhesion in uremic dysfunction
⏱️ Onset: 30–90 min ⏳ Duration: 4–8 h
#NephJC
May 14, 2025 at 1:08 AM
T0c
So how does DDAVP skip the bleeding drama? 🩸
🧬 Desmopressin → triggers cAMP → exocytosis of vWF & FVIII from endothelium
➡️ Boosts platelet adhesion in uremic dysfunction
⏱️ Onset: 30–90 min ⏳ Duration: 4–8 h
#NephJC
So how does DDAVP skip the bleeding drama? 🩸
🧬 Desmopressin → triggers cAMP → exocytosis of vWF & FVIII from endothelium
➡️ Boosts platelet adhesion in uremic dysfunction
⏱️ Onset: 30–90 min ⏳ Duration: 4–8 h
#NephJC
We used to do pre procedure DDAVP for abnormal PFA’s, mostly in CKD/ uremic kids
# NephJC
# NephJC
May 14, 2025 at 1:12 AM
We used to do pre procedure DDAVP for abnormal PFA’s, mostly in CKD/ uremic kids
# NephJC
# NephJC
Reposted by Shweta Shah
Join hosts Emily Zangla and Jordy Salcedo with moderators from four nephrology sessions at the 2025 Pediatric Academic Societies Conference in Honolulu, Hawaii.
buff.ly/HdQWefG
buff.ly/HdQWefG
May 2, 2025 at 2:02 PM
Join hosts Emily Zangla and Jordy Salcedo with moderators from four nephrology sessions at the 2025 Pediatric Academic Societies Conference in Honolulu, Hawaii.
buff.ly/HdQWefG
buff.ly/HdQWefG
Anyone seen membranous nephropathy( PLA2r neg) in pt with long standing Thal major, transfusion dependent?
#NephSky #askrenal @askrenal.bsky.social
#NephSky #askrenal @askrenal.bsky.social
April 30, 2025 at 4:19 PM
Anyone seen membranous nephropathy( PLA2r neg) in pt with long standing Thal major, transfusion dependent?
#NephSky #askrenal @askrenal.bsky.social
#NephSky #askrenal @askrenal.bsky.social
Reposted by Shweta Shah
🚨 The ASPN Scavenger Hunt is almost here!
🗓 Launches April 25 – are you ready?
✅ Download the ASPN Go App now
Complete tasks ➡ Win prizes!
🎁 Daily Yeti Cups + a grand prize Amazon Gift Card
#ASPNHunt #ComingSoon buff.ly/br6ocqR
🗓 Launches April 25 – are you ready?
✅ Download the ASPN Go App now
Complete tasks ➡ Win prizes!
🎁 Daily Yeti Cups + a grand prize Amazon Gift Card
#ASPNHunt #ComingSoon buff.ly/br6ocqR
April 22, 2025 at 2:02 PM
🚨 The ASPN Scavenger Hunt is almost here!
🗓 Launches April 25 – are you ready?
✅ Download the ASPN Go App now
Complete tasks ➡ Win prizes!
🎁 Daily Yeti Cups + a grand prize Amazon Gift Card
#ASPNHunt #ComingSoon buff.ly/br6ocqR
🗓 Launches April 25 – are you ready?
✅ Download the ASPN Go App now
Complete tasks ➡ Win prizes!
🎁 Daily Yeti Cups + a grand prize Amazon Gift Card
#ASPNHunt #ComingSoon buff.ly/br6ocqR
Attending #PAS2025 ? Fun way to engage with fellow nephrons through our ASPN Go App!!📱📲
#pedsneph #ASPNHunt
@aspnr.bsky.social @nefronica-2rair.bsky.social @drm-sudha.bsky.social @sugarkro.bsky.social @asouth-neph.bsky.social
#pedsneph #ASPNHunt
@aspnr.bsky.social @nefronica-2rair.bsky.social @drm-sudha.bsky.social @sugarkro.bsky.social @asouth-neph.bsky.social
April 22, 2025 at 1:44 PM
Attending #PAS2025 ? Fun way to engage with fellow nephrons through our ASPN Go App!!📱📲
#pedsneph #ASPNHunt
@aspnr.bsky.social @nefronica-2rair.bsky.social @drm-sudha.bsky.social @sugarkro.bsky.social @asouth-neph.bsky.social
#pedsneph #ASPNHunt
@aspnr.bsky.social @nefronica-2rair.bsky.social @drm-sudha.bsky.social @sugarkro.bsky.social @asouth-neph.bsky.social
Reposted by Shweta Shah
Skeleton Key Group still going strong with their 37th electrolyte case
www.renalfellow.org/2025/03/19/s...
www.renalfellow.org/2025/03/19/s...
Skeleton Key Group Case #37: A case of elevated anion gap metabolic acidosis
Welcome to the 37th case of the Skeleton Key Group, a team of nephrologists from around the world who build a periodic education package for the Renal Fellow Ne
www.renalfellow.org
March 25, 2025 at 8:34 PM
Skeleton Key Group still going strong with their 37th electrolyte case
www.renalfellow.org/2025/03/19/s...
www.renalfellow.org/2025/03/19/s...
#NephMadness party ✅
Were there cookies? ❌
Was it a great discussion? ✅✅
Some were resistant, some needed incremental push, lot of disasters and conflicts, but finally convinced!!🤣🤣🤣
@nephmadness.bsky.social
Genetics in FSGS 🏆
Were there cookies? ❌
Was it a great discussion? ✅✅
Some were resistant, some needed incremental push, lot of disasters and conflicts, but finally convinced!!🤣🤣🤣
@nephmadness.bsky.social
Genetics in FSGS 🏆
March 25, 2025 at 9:50 PM
#NephMadness party ✅
Were there cookies? ❌
Was it a great discussion? ✅✅
Some were resistant, some needed incremental push, lot of disasters and conflicts, but finally convinced!!🤣🤣🤣
@nephmadness.bsky.social
Genetics in FSGS 🏆
Were there cookies? ❌
Was it a great discussion? ✅✅
Some were resistant, some needed incremental push, lot of disasters and conflicts, but finally convinced!!🤣🤣🤣
@nephmadness.bsky.social
Genetics in FSGS 🏆
After listening to this podcast, i might be a convert now!
Genetic counseling might be more important than sending genetic testing!!
@nephmadness.bsky.social #NephMadness
Genetic counseling might be more important than sending genetic testing!!
@nephmadness.bsky.social #NephMadness
March 25, 2025 at 1:55 PM
After listening to this podcast, i might be a convert now!
Genetic counseling might be more important than sending genetic testing!!
@nephmadness.bsky.social #NephMadness
Genetic counseling might be more important than sending genetic testing!!
@nephmadness.bsky.social #NephMadness
Love the science behind anti-nephrin Ab but
35% AA have one risk allele for APOL-1 & 14% have 2 risk alleles!
Those r huge number of people predisposed to AMKD!
IMO, it will be the winner , it has to🤣
@nephmadness.bsky.social
35% AA have one risk allele for APOL-1 & 14% have 2 risk alleles!
Those r huge number of people predisposed to AMKD!
IMO, it will be the winner , it has to🤣
@nephmadness.bsky.social
March 25, 2025 at 12:34 AM
Love the science behind anti-nephrin Ab but
35% AA have one risk allele for APOL-1 & 14% have 2 risk alleles!
Those r huge number of people predisposed to AMKD!
IMO, it will be the winner , it has to🤣
@nephmadness.bsky.social
35% AA have one risk allele for APOL-1 & 14% have 2 risk alleles!
Those r huge number of people predisposed to AMKD!
IMO, it will be the winner , it has to🤣
@nephmadness.bsky.social