Naeha Subramanian
@naehasubramanian.bsky.social
Associate Professor at the Institute for Systems Biology and Univ. of Washington focussed on innate immunity and its role in infectious disease, autoimmunity and cancer.
Pinned
Lab Manager I
The Subramanian Lab is seeking a highly motivated and capable Lab Manager I to oversee vivarium operations, manage general lab maintenance and procurement, and contribute directly to research efforts ...
isbscience.bamboohr.com
We're hiring! Our lab @ISB is looking for a full-time Research Associate to manage our mouse colony 🐭, run experiments in a Type 1 diabetes model, and help keep the lab running smoothly.
Ideal for someone aiming for grad school or further scientific training. isbscience.bamboohr.com/careers/56
Ideal for someone aiming for grad school or further scientific training. isbscience.bamboohr.com/careers/56
Reposted by Naeha Subramanian
Dr. Mary Brunkow is a 2025 Nobel laureate. In today’s @isbscience.org press conference, she shares the FOXP3 story, from a puzzling mouse to a discovery that reshaped immunology.
🎥 Watch the full video: youtu.be/vg61fbycGEk
🎥 Watch the full video: youtu.be/vg61fbycGEk
Mary Brunkow Wins 2025 Nobel Prize | ISB Press Conference (Full)
YouTube video by Institute for Systems Biology
youtu.be
October 8, 2025 at 2:12 AM
Dr. Mary Brunkow is a 2025 Nobel laureate. In today’s @isbscience.org press conference, she shares the FOXP3 story, from a puzzling mouse to a discovery that reshaped immunology.
🎥 Watch the full video: youtu.be/vg61fbycGEk
🎥 Watch the full video: youtu.be/vg61fbycGEk
Reposted by Naeha Subramanian
Rubbing shoulders with a @nobelprize.bsky.social laureate! 🤩What a week!
Couldn’t have happened to a nicer person: isbscience.org/news/press-r...
@isbscience.org @naehasubramanian.bsky.social @flash-point.bsky.social @annabiosys.bsky.social
Couldn’t have happened to a nicer person: isbscience.org/news/press-r...
@isbscience.org @naehasubramanian.bsky.social @flash-point.bsky.social @annabiosys.bsky.social
October 8, 2025 at 12:19 AM
Rubbing shoulders with a @nobelprize.bsky.social laureate! 🤩What a week!
Couldn’t have happened to a nicer person: isbscience.org/news/press-r...
@isbscience.org @naehasubramanian.bsky.social @flash-point.bsky.social @annabiosys.bsky.social
Couldn’t have happened to a nicer person: isbscience.org/news/press-r...
@isbscience.org @naehasubramanian.bsky.social @flash-point.bsky.social @annabiosys.bsky.social
Reposted by Naeha Subramanian
Many congratulations, Mary Brunkow! Couldn’t be happier for you and @isbscience.org ! ♥️
www.nobelprize.org
www.nobelprize.org
The official website of the Nobel Prize - NobelPrize.org
The Nobel Prize rewards science, humanism and peace efforts. This is one of the central concepts in the will of Alfred Nobel, and it also permeates the outreach activities that have been developed for...
www.nobelprize.org
October 6, 2025 at 11:46 AM
Many congratulations, Mary Brunkow! Couldn’t be happier for you and @isbscience.org ! ♥️
www.nobelprize.org
www.nobelprize.org
Reposted by Naeha Subramanian
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
October 6, 2025 at 9:51 AM
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
Reposted by Naeha Subramanian
Excited to finally present the lab's latest work in defining candidate causal genetic variants that drive autoimmune diseases and their effects on primary human T cell expression and function! www.nature.com/articles/s41...
Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks - Nature Genetics
Massively parallel reporter assay in primary human CD4+ T cells and bulk and single-cell CRISPR-interference screens identify candidate causal variants linked to autoimmune disease risk that modulate ...
www.nature.com
September 18, 2025 at 8:50 PM
Excited to finally present the lab's latest work in defining candidate causal genetic variants that drive autoimmune diseases and their effects on primary human T cell expression and function! www.nature.com/articles/s41...
Reposted by Naeha Subramanian
September 20, 2025 at 1:27 PM
Reposted by Naeha Subramanian
September 23, 2025 at 1:06 AM
Reposted by Naeha Subramanian
Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be."
September 7, 2025 at 8:04 PM
Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be."
Reposted by Naeha Subramanian
Please read this wonderful article about my fabulous partner in life, Dr Jennifer Quinn and her work at the Seattle Math Museum! Spread the mathematical joy! @jennifer.j.quinn
www.geekwire.com/2025/seattle...
www.geekwire.com/2025/seattle...
Seattle’s traveling math magician on why problem-solving matters more than ever in the age of AI
Jenny Quinn, executive director of the Seattle Universal Math Museum, shows off a solved Fibonacci sequence puzzle. (GeekWire Photo / Maddie Stoll) Jenny
www.geekwire.com
September 7, 2025 at 1:16 AM
Please read this wonderful article about my fabulous partner in life, Dr Jennifer Quinn and her work at the Seattle Math Museum! Spread the mathematical joy! @jennifer.j.quinn
www.geekwire.com/2025/seattle...
www.geekwire.com/2025/seattle...
Reposted by Naeha Subramanian
Postdoc position (please re-post)
A funded postdoctoral position, will open in 2026 to study aspects of Neisseria gonorrhoeae pathogenesis, antigenic variation, genetics, or physiology.
If interested in more information, please contact Hank Seifert
h-seifert@northwestern.edu
#MicroSky
A funded postdoctoral position, will open in 2026 to study aspects of Neisseria gonorrhoeae pathogenesis, antigenic variation, genetics, or physiology.
If interested in more information, please contact Hank Seifert
h-seifert@northwestern.edu
#MicroSky
September 6, 2025 at 7:32 PM
Postdoc position (please re-post)
A funded postdoctoral position, will open in 2026 to study aspects of Neisseria gonorrhoeae pathogenesis, antigenic variation, genetics, or physiology.
If interested in more information, please contact Hank Seifert
h-seifert@northwestern.edu
#MicroSky
A funded postdoctoral position, will open in 2026 to study aspects of Neisseria gonorrhoeae pathogenesis, antigenic variation, genetics, or physiology.
If interested in more information, please contact Hank Seifert
h-seifert@northwestern.edu
#MicroSky
We're hiring! Our lab @ISB is looking for a full-time Research Associate to manage our mouse colony 🐭, run experiments in a Type 1 diabetes model, and help keep the lab running smoothly.
Ideal for someone aiming for grad school or further scientific training. isbscience.bamboohr.com/careers/56
Ideal for someone aiming for grad school or further scientific training. isbscience.bamboohr.com/careers/56
Lab Manager I
The Subramanian Lab is seeking a highly motivated and capable Lab Manager I to oversee vivarium operations, manage general lab maintenance and procurement, and contribute directly to research efforts ...
isbscience.bamboohr.com
September 6, 2025 at 10:32 PM
We're hiring! Our lab @ISB is looking for a full-time Research Associate to manage our mouse colony 🐭, run experiments in a Type 1 diabetes model, and help keep the lab running smoothly.
Ideal for someone aiming for grad school or further scientific training. isbscience.bamboohr.com/careers/56
Ideal for someone aiming for grad school or further scientific training. isbscience.bamboohr.com/careers/56
Reposted by Naeha Subramanian
My heart. Members of the US Public Health Service (the uniformed service branch no one has ever heard of, who serve at the CDC and elsewhere in the US), massed within the CDC property, saluting their departing uniformed leaders who were escorted out by security today after resigning on principle.
A higher resolution pic than my screenshot that captured the salute, from Alyssa Pointer (Reuters) – press weren’t allowed past the front gate for security reasons.
August 29, 2025 at 3:36 AM
My heart. Members of the US Public Health Service (the uniformed service branch no one has ever heard of, who serve at the CDC and elsewhere in the US), massed within the CDC property, saluting their departing uniformed leaders who were escorted out by security today after resigning on principle.
Reposted by Naeha Subramanian
CDC staff held a “clap-out” on Thursday to honor three of the agency’s high-ranking officials, who resigned in protest after President Trump fired the director, Susan Monarez. nyti.ms/4oSxakJ
August 29, 2025 at 12:00 AM
CDC staff held a “clap-out” on Thursday to honor three of the agency’s high-ranking officials, who resigned in protest after President Trump fired the director, Susan Monarez. nyti.ms/4oSxakJ
Reposted by Naeha Subramanian
Abbe Lowell and I represent CDC Director #SusanMonarez. Contrary to govt statements, Dr. Monarez has neither resigned nor yet been fired. She will not resign. We have issued the following statement:
August 27, 2025 at 11:15 PM
Abbe Lowell and I represent CDC Director #SusanMonarez. Contrary to govt statements, Dr. Monarez has neither resigned nor yet been fired. She will not resign. We have issued the following statement:
Reposted by Naeha Subramanian
“Putin would eat you for lunch.”
Today, exactly that happened.
Today, exactly that happened.
August 15, 2025 at 11:48 PM
“Putin would eat you for lunch.”
Today, exactly that happened.
Today, exactly that happened.
Reposted by Naeha Subramanian
Let's please keep the remaining staff at NIH, NSF, etc in our thoughts even as you lose sleep over your own lab and scientific career.
They are enduring pure chaos to try to hold the fort.
See snapshot from wapo.st/4feKKuu (gift 🔗) saying they are "barely holding it together"
They are enduring pure chaos to try to hold the fort.
See snapshot from wapo.st/4feKKuu (gift 🔗) saying they are "barely holding it together"
July 30, 2025 at 3:51 PM
Let's please keep the remaining staff at NIH, NSF, etc in our thoughts even as you lose sleep over your own lab and scientific career.
They are enduring pure chaos to try to hold the fort.
See snapshot from wapo.st/4feKKuu (gift 🔗) saying they are "barely holding it together"
They are enduring pure chaos to try to hold the fort.
See snapshot from wapo.st/4feKKuu (gift 🔗) saying they are "barely holding it together"
Reposted by Naeha Subramanian
Shout out to the WSJ journalists who reported on Vought’s impoundment by footnote, causing the White House to walk it back. Impact journalism!!
UPDATE: The pause was scrapped Tuesday evening after intervention by top White House officials. www.wsj.com/politics/pol...
Trump Administration Scraps Effort to Pause Health-Research Funding
The administration halted and then restarted billions in new research grants flowing from the National Institutes of Health.
www.wsj.com
July 30, 2025 at 4:00 AM
Shout out to the WSJ journalists who reported on Vought’s impoundment by footnote, causing the White House to walk it back. Impact journalism!!
Reposted by Naeha Subramanian
Now up, led by Ashton Omdahl! Our method GLEANR finds shared genetic factors across lots of GWAS, and handles spurious correlation driven by cohort overlap. Neat examples of factors driving related traits with enrichment in different cell types / developmental stages.
📣New from @alexisbattle.bsky.social & co!
📄Sparse matrix factorization robust to sample sharing across GWASs reveals interpretable genetic components
📄Sparse matrix factorization robust to sample sharing across GWASs reveals interpretable genetic components
Sparse matrix factorization robust to sample sharing across GWASs reveals interpretable genetic components
We developed a computational method to identify genetic pathways shared among complex
traits that applies matrix factorization to decompose genetic associations across
hundreds of phenotypes. Our meth...
www.cell.com
July 28, 2025 at 7:47 PM
Now up, led by Ashton Omdahl! Our method GLEANR finds shared genetic factors across lots of GWAS, and handles spurious correlation driven by cohort overlap. Neat examples of factors driving related traits with enrichment in different cell types / developmental stages.
Reposted by Naeha Subramanian
The NIH was healthiest when pay lines were in the 20th percentile range.
We are headed into an environment where pay lines are in the 5% range.
In my entire career, I’ve only had 3 grants that scored better than 5%. And my lab is considered a successful one.
This is going to destroy science.
We are headed into an environment where pay lines are in the 5% range.
In my entire career, I’ve only had 3 grants that scored better than 5%. And my lab is considered a successful one.
This is going to destroy science.
July 28, 2025 at 8:12 PM
The NIH was healthiest when pay lines were in the 20th percentile range.
We are headed into an environment where pay lines are in the 5% range.
In my entire career, I’ve only had 3 grants that scored better than 5%. And my lab is considered a successful one.
This is going to destroy science.
We are headed into an environment where pay lines are in the 5% range.
In my entire career, I’ve only had 3 grants that scored better than 5%. And my lab is considered a successful one.
This is going to destroy science.
Reposted by Naeha Subramanian
When we held our rally after the roundtable on Monday to support the #NIH science, we invited Jay Bhattacharya to join us.
He declined saying he was disappointed we “made it political.”
But supporting NIH isn’t partisan! www.politico.com/news/2025/07...
He declined saying he was disappointed we “made it political.”
But supporting NIH isn’t partisan! www.politico.com/news/2025/07...
14 Republican senators urge White House to release delayed NIH funds
Sen. Katie Britt (R-Ala.) is leading the letter making the ask of OMB director Russ Vought.
www.politico.com
July 26, 2025 at 1:16 AM
When we held our rally after the roundtable on Monday to support the #NIH science, we invited Jay Bhattacharya to join us.
He declined saying he was disappointed we “made it political.”
But supporting NIH isn’t partisan! www.politico.com/news/2025/07...
He declined saying he was disappointed we “made it political.”
But supporting NIH isn’t partisan! www.politico.com/news/2025/07...
Reposted by Naeha Subramanian
Evolutionary molecular biology paying dividends again - this time in finding new modulators of innate immunity - www.science.org/doi/10.1126/...
A human homolog of SIR2 antiphage proteins mediates immunity via the Toll-like receptor pathway
Key actors of mammalian immunity originated from bacterial antiphage systems. The full extent of immune system conservation between bacteria and eukaryotes is unknown. Here, we show that the silent in...
www.science.org
July 26, 2025 at 1:39 AM
Evolutionary molecular biology paying dividends again - this time in finding new modulators of innate immunity - www.science.org/doi/10.1126/...
Reposted by Naeha Subramanian
Happy Birthday, Rosalind Franklin. She captured an X-ray diffraction image of DNA and stated that a helical structure was probable. Watson and Crick then created a detailed model based on her results. They initially received credit for the discovery and were awarded the Nobel Prize after her death.🧪
July 26, 2025 at 6:05 AM
Happy Birthday, Rosalind Franklin. She captured an X-ray diffraction image of DNA and stated that a helical structure was probable. Watson and Crick then created a detailed model based on her results. They initially received credit for the discovery and were awarded the Nobel Prize after her death.🧪
Reposted by Naeha Subramanian
Another Bhattacharya email today
1/4
1/4
July 24, 2025 at 11:47 PM
Another Bhattacharya email today
1/4
1/4
Reposted by Naeha Subramanian
Abughazaleh: I am from one of those families. I do not want Israeli children to live in fear. And I don't want gazan children to starve to death. And there is no enemy of either state that could want me to wish that or excuse the starvation of children. It is that simple.
July 25, 2025 at 2:19 AM
Abughazaleh: I am from one of those families. I do not want Israeli children to live in fear. And I don't want gazan children to starve to death. And there is no enemy of either state that could want me to wish that or excuse the starvation of children. It is that simple.