Emile Gluck-Thaler
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mycomile.bsky.social
Emile Gluck-Thaler
@mycomile.bsky.social
Understanding fungal interactions using genes, genomes and Starships 🧬🍄🚀Evolutionary Biologist and Asst Prof @UWMadison's Dept. of Plant Pathology | he/him |
plantpath.wisc.edu/faculty/emile-gluck-thaler/
Pinned
We dive into the dynamics of #starships 🚀 in a fungal pathogen to ask: how might these giant #transposons impact human health? We find they drive genome-wide variation, encode clinically-relevant traits and even transpose within the same strain! 🍄🧪 out today in mBio #goteam doi.org/10.1128/mbio...
Giant transposons promote strain heterogeneity in a major fungal pathogen | mBio
No “one size fits all” option exists for treating fungal infections in large part due to genetic and phenotypic variability among strains. Accounting for strain heterogeneity is thus fundamental for d...
doi.org
Reposted by Emile Gluck-Thaler
Excited to do a postdoc in beautiful Neuchatel / Switzerland🇨🇭?

We have several postdoc positions open at the moment!

Check our website for the full ads here: pathogen-genomics.org/jobs

Happy to answer any question and please spread the word to anyone who might be interested!
April 25, 2025 at 11:20 AM
Reposted by Emile Gluck-Thaler
I am honoured and delighted to join the #CIFAR family as an Azrieli Global Scholar.

Looking forward to working with this fantastic community to tackle complex global challenges through interdisciplinary collaboration!

cifar.ca/cifarnews/20...
May 22, 2025 at 6:36 PM
We dive into the dynamics of #starships 🚀 in a fungal pathogen to ask: how might these giant #transposons impact human health? We find they drive genome-wide variation, encode clinically-relevant traits and even transpose within the same strain! 🍄🧪 out today in mBio #goteam doi.org/10.1128/mbio...
Giant transposons promote strain heterogeneity in a major fungal pathogen | mBio
No “one size fits all” option exists for treating fungal infections in large part due to genetic and phenotypic variability among strains. Accounting for strain heterogeneity is thus fundamental for d...
doi.org
May 13, 2025 at 8:11 AM
Reposted by Emile Gluck-Thaler
New risk maps developed by Sandip Mondal, @mycomile.bsky.social, Horacio Lopez-Nicora, and others, help soybean farmers spot charcoal rot before it strikes​​. 🫛 Read the press release: www.apsnet.org/about/newsro...

Read the original article in Phytopathology: doi.org/10.1094/PHYT...
April 24, 2025 at 6:25 PM
Reposted by Emile Gluck-Thaler
The new extended deadline for MSA abstracts is March 21st! #MSAfungi25
📣Call for Abstracts for the Mycological Society of America 2025 Annual Meeting this summer in Madison, Wisconsin. Submit your abstract by March 17th! #MSAfungi25

msa.joynconference.com/v2/
March 14, 2025 at 7:15 PM
Reposted by Emile Gluck-Thaler
Are you a member of @msafungi.bsky.social and employee of the US Federal Government who recently lost their job or who otherwise needs support during recent implementation of executive orders? We would like to connect with you to understand how the Society can help. Please DM to let us know.
February 27, 2025 at 12:24 PM
Its #fungus time! Come join us in Madison this summer for #MSAfungi25 🧪🍄🔬 Abstracts due March 17
📣Call for Abstracts for the Mycological Society of America 2025 Annual Meeting this summer in Madison, Wisconsin. Submit your abstract by March 17th! #MSAfungi25

msa.joynconference.com/v2/
March 11, 2025 at 1:46 PM
Reposted by Emile Gluck-Thaler
📣Call for Abstracts for the Mycological Society of America 2025 Annual Meeting this summer in Madison, Wisconsin. Submit your abstract by March 17th! #MSAfungi25

msa.joynconference.com/v2/
February 17, 2025 at 10:08 AM
Reposted by Emile Gluck-Thaler
A campaign to match scientists who've been unjustly fired from federal positions with illustrators to tell their stories — this looks pretty neat
They can’t fire science. Tell your story: bit.ly/faces_of_science
March 7, 2025 at 5:51 PM
Reposted by Emile Gluck-Thaler
🚨 Washington State asked a judge yesterday to hold the Trump admin in contempt for canceling a grant to Seattle Children’s to study gender-affirming care.

“Injunctions are not suggestions — they are binding orders of the Court. Defendants may not evade this Court’s orders through game-playing.”
NEW: The NIH has begun terminating grants for active projects studying gender identity, DEI, environmental justice, climate change, among other topics.

At least 16 termination letters have already been sent — and hundreds more are coming, people inside NIH tell me.
www.nature.com/articles/d41...
Exclusive: NIH to terminate hundreds of active research grants
Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.
www.nature.com
March 7, 2025 at 5:08 PM
We show eukaryotic #HGT across >100 million years of evolution through simple co-culture: the fungal equivalent of taking yourself for a swim with a platypus and walking away with a new bill 🧪🍄🦆🚀 Great work everyone!
We did it! We caught Starship #transposons moving between #fungal species in the lab, including between species separated by ~100my. We think Starships are a mediator of HGT in fungi, akin to conjugative elements in bacteria. Check out the preprint. www.biorxiv.org/content/10.1...
March 7, 2025 at 1:51 PM
Reposted by Emile Gluck-Thaler
If you loved #ECFG17 (or had FOMO seeing posts of all the cool research) consider connecting with the fungal community virtually this summer at #CFN25 🍄

We'll be opening registration soon! Follow us to stay up to date!
It's happening! We are coming back with virtual meetings! Save The Date - August 6-8, 2025. 📅🇨🇦🍄🛜. Check your emails or social media for more details. PS. Contact us if you want to receive emails! #CFN25 #SaveTheDate #FungiareBack
March 6, 2025 at 9:14 AM
Reposted by Emile Gluck-Thaler
How do you find Starships in fungal genomes?

Starfish or course! ⭐🎣

Developed by @mycomile.bsky.social

#ecfg17 @fungage-lab.bsky.social

Try it out on your pezizo genome!

github.com/egluckthaler...
March 4, 2025 at 12:00 PM
Reposted by Emile Gluck-Thaler
We are experiencing an assault on science unparalleled by anything I’ve seen in my life. It’s not one issue or another anymore, the entire institution is under attack by the most powerful individuals in the country.

This Friday, where will you be?

standupforscience2025.org
March 2, 2025 at 4:27 PM
Huge thank you to the Cornell Plant Path grad students for inviting me out to meet and speak with them 🙏🧬🍄 uncertain times now, but seeing all their passion and drive gives me hope for the future of #science
February 20, 2025 at 9:12 PM
Reposted by Emile Gluck-Thaler
Elon Musk has now illegally fired:

- USDA employees amidst a bird flu outbreak

- FAA chair amid a plane crash epidemic

- People in charge of protecting us from nuclear attack

At this point Musk has to be considered a terrorist attacking the United States.
February 19, 2025 at 1:14 AM
Reposted by Emile Gluck-Thaler
@asm.org this better not be anticipatory obedience. I have 5 lab members planning on going to ASM microbe this year. I will absolutely pivot to another meeting if ASM gives in to anti-DEI efforts.
@vscooper.micropopbio.org and @mostlymicrobes.bsky.social while downloading scientist spotlights for teaching from the site; ASM has also scrubbed the entire IDEAA page including resources on LGBTQ+ scientists at asm.org/IDEAA/resources/pride-month
February 2, 2025 at 6:30 PM
Reposted by Emile Gluck-Thaler
Following thermal adaptation, we investigated Zymoseptoria tritici's responses to extreme temperature stresses using transcriptomics and kmer-based GWAS.

🌡️🧬 Check out our findings in the preprint: biorxiv.org/content/10.1...
January 17, 2025 at 4:06 PM
Reposted by Emile Gluck-Thaler
@tbadet.bsky.social and I have a preprint out on transposon silencing in fungi!

Genome size evolution is fascinating and showcases the dynamic nature of transposon activation.

What we understand less are the dynamics of transposon defense systems encoded by the genomes.

doi.org/10.1101/2025...
January 16, 2025 at 9:09 PM
Reposted by Emile Gluck-Thaler
From lesions to lessons:
2025 marks the 20th anniversary of filamentous plant pathogen genomics. In our new review, we present lessons we learned over the past 2 decades and discuss the future of plant pathogen genomics. Take a first look!

apsjournals.apsnet.org/doi/10.1094/...
From Lesions to Lessons: Two Decades of Filamentous Plant Pathogen Genomics | Molecular Plant-Microbe Interactions®
Filamentous plant pathogens pose a severe threat to food security. Current estimates suggest up to 23% yield losses to pre- and post-harvest diseases and these losses are projected to increase due to ...
apsjournals.apsnet.org
January 20, 2025 at 9:51 AM
What an awesome story! amazing to see so many connections with virulence factors 🤯🌱🚀
📣New year, new preprint @biorxiv-microbiol.bsky.social 🎉! A study led by the brilliant @yukiyosato.bsky.social showing that Starship giant transposons dominate plastic genomic regions in the fungal plant pathogen Verticillium dahliae and drive virulence evolution. 🧵[1/12] doi.org/10.1101/2025...
Starship giant transposons dominate plastic genomic regions in a fungal plant pathogen and drive virulence evolution
Starships form a recently discovered superfamily of giant transposons in Pezizomycotina fungi, implicated in mediating horizontal transfer of diverse cargo genes between fungal genomes. Their elusive nature has long obscured their significance, and their impact on genome evolution remains poorly understood. Here, we reveal a surprising abundance and diversity of Starships in the phytopathogenic fungus Verticillium dahliae. Remarkably, Starships dominate the plastic genomic compartments involved in host colonization, are enriched in virulence-associated genes, and exhibit genetic and epigenetic characteristics associated with adaptive genome evolution. We further uncover extensive horizontal transfer of Starships between Verticillium species and, strikingly, from distantly related Fusarium fungi. Finally, we demonstrate how Starship activity facilitated the de novo formation of a novel virulence gene. Our findings illuminate the profound influence of Starship dynamics on fungal genome evolution and the development of virulence. ### Competing Interest Statement The authors have declared no competing interest.
doi.org
January 11, 2025 at 10:44 PM
Reposted by Emile Gluck-Thaler
We're launching our Bluesky feed with Starships! Check out our December issue for a featured review on these gigantic transposable elements written by Emile Gluck-Thaler and colleagues.

There's plenty more inside the issue! The complete Table of Contents is here:
www.cell.com/trends/genet...
December 12, 2024 at 9:46 PM
Excited to share our review on everything we know so far about #fungal #starships and new questions to take the field forward 🚀🍄 Great work team! @fungage-lab.bsky.social
Thrilled to have our recent review on giant #fungal #transposons, called Starships, featured on the cover of Trends in Genetics! Accompanied by some fantastic artwork! With @mycomile.bsky.social. www.cell.com/trends/genet...
December 4, 2024 at 4:06 PM
Reposted by Emile Gluck-Thaler
Thrilled to have our recent review on giant #fungal #transposons, called Starships, featured on the cover of Trends in Genetics! Accompanied by some fantastic artwork! With @mycomile.bsky.social. www.cell.com/trends/genet...
December 3, 2024 at 10:02 AM
Reposted by Emile Gluck-Thaler
NEW Publication!😄

Here, we show how #PhyKIT — a broadly applicable toolkit for #phylogenomics — can be used to construct phylogenomic data matrices (& quantify biases therein), detect anomalies in predicted orthology, calculate gene-gene coevolution, & more!

🔗: tinyurl.com/yc5ja4xz
November 25, 2024 at 5:25 PM