Matthew Schmitz
@mtvector.bsky.social
Evolutionary neuroscientist 🐳 seeking cool papers
Relieved to finally post my whole developing brain evolutionary "theory of everything" preprint!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
ANTIPODE Provides a Global View of Cell Type Homology and Transcriptomic Divergence in the Developing Mammalian Brain
Diverse neurons and glia are generated in conserved spatial and temporal sequences during mammalian brain development. Divergence in gene regulatory networks can alter brain composition, scaling, timi...
www.biorxiv.org
October 20, 2025 at 2:50 AM
Relieved to finally post my whole developing brain evolutionary "theory of everything" preprint!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
This is also what it's like to finish a cortical layer dissection...
August 11, 2025 at 10:35 PM
This is also what it's like to finish a cortical layer dissection...
Reposted by Matthew Schmitz
Very proud of two new preprints from the lab:
1) CREsted: to train sequence-to-function deep learning models on scATAC-seq atlases, and use them to decipher enhancer logic and design synthetic enhancers. This has been a wonderful lab-wide collaborative effort. www.biorxiv.org/content/10.1...
1) CREsted: to train sequence-to-function deep learning models on scATAC-seq atlases, and use them to decipher enhancer logic and design synthetic enhancers. This has been a wonderful lab-wide collaborative effort. www.biorxiv.org/content/10.1...
CREsted: modeling genomic and synthetic cell type-specific enhancers across tissues and species
Sequence-based deep learning models have become the state of the art for the analysis of the genomic regulatory code. Particularly for transcriptional enhancers, deep learning models excel at decipher...
www.biorxiv.org
April 4, 2025 at 9:04 AM
Very proud of two new preprints from the lab:
1) CREsted: to train sequence-to-function deep learning models on scATAC-seq atlases, and use them to decipher enhancer logic and design synthetic enhancers. This has been a wonderful lab-wide collaborative effort. www.biorxiv.org/content/10.1...
1) CREsted: to train sequence-to-function deep learning models on scATAC-seq atlases, and use them to decipher enhancer logic and design synthetic enhancers. This has been a wonderful lab-wide collaborative effort. www.biorxiv.org/content/10.1...
What a robust and slightly threatening solution for demuxing, doublet detection,etc for multiplex single cell genomics experiments!
March 24, 2025 at 7:45 PM
What a robust and slightly threatening solution for demuxing, doublet detection,etc for multiplex single cell genomics experiments!
Reposted by Matthew Schmitz
Wanna save the taxpayer money?
Don’t buy any Teslas.
Don’t buy any Teslas.
Apparently Tesla isn't selling any cars which also means it's not selling carbon credits. It made 2.7 billion in carbon credits last year. Carbon credits is largely what has kept the company afloat
Tesla's Sales Are Falling So Much That the Cash It Rakes in for Carbon Credits Is Under Threat
An important source of carbon credit revenue could quickly dry up for Tesla. And the pressure is on, experts warn.
futurism.com
March 7, 2025 at 12:08 AM
Wanna save the taxpayer money?
Don’t buy any Teslas.
Don’t buy any Teslas.
Reposted by Matthew Schmitz
Pleasure to co-edit this issue of Current Opinion on human genetic origins with @steinlab.bsky.social:
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
Current Opinion in Genetics & Development | Genetics of Human Origin (2024) | ScienceDirect.com by ElsevierScienceDirect
Identification of the genetic variants underlying distinctive human traits provides a new perspective on human origins. However, complete descriptions of genetic variants under selective pressure alon...
www.sciencedirect.com
February 27, 2025 at 5:56 PM
Pleasure to co-edit this issue of Current Opinion on human genetic origins with @steinlab.bsky.social:
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
Amidst the chaos, my partner was featured in this WaPo article about one more way that the administration is undermining the future of American Government www.washingtonpost.com/politics/202...
So that's kinda fun right? 🥲😭
So that's kinda fun right? 🥲😭
www.washingtonpost.com
February 26, 2025 at 7:01 AM
Amidst the chaos, my partner was featured in this WaPo article about one more way that the administration is undermining the future of American Government www.washingtonpost.com/politics/202...
So that's kinda fun right? 🥲😭
So that's kinda fun right? 🥲😭
Reposted by Matthew Schmitz
We need to make sure that everyone understands how important science is for EVERYONE not just for scientists...
Get in dorks, we're going protesting!
STAND UP FOR SCIENCE WITH US ON MARCH 7TH, 2025
WASHINGTON DC AND EVERY STATE CAPITOL
Because science is for everyone!
Find us at www.standupforscience2025.org
#standupforscience2025 #scienceforall #sciencenotsilence
STAND UP FOR SCIENCE WITH US ON MARCH 7TH, 2025
WASHINGTON DC AND EVERY STATE CAPITOL
Because science is for everyone!
Find us at www.standupforscience2025.org
#standupforscience2025 #scienceforall #sciencenotsilence
February 22, 2025 at 5:42 PM
We need to make sure that everyone understands how important science is for EVERYONE not just for scientists...
We know by looking at the demographics of STEM faculty the system is biased against all sorts of people. With the murder of diversity supplements etc, what are we doing as a field to ensure a future of diverse people and ideas in science?
“What this does is discriminate against people who are underrepresented,” The reviewer added that evaluation for the general and diversity pools are the same. “I can’t stress enough that an undeserving grant “is not going to get funded, whether it’s diversity or not”
www.nytimes.com/2025/02/22/s...
www.nytimes.com/2025/02/22/s...
Accessibility Is Taking a Hit Across the Sciences (Gift Article)
Confusion has ensued about the future of programs and research supporting people with disabilities as a result of President Trump’s executive order.
www.nytimes.com
February 22, 2025 at 6:21 PM
We know by looking at the demographics of STEM faculty the system is biased against all sorts of people. With the murder of diversity supplements etc, what are we doing as a field to ensure a future of diverse people and ideas in science?
@chanzuckerberg.bsky.social why? If you're mostly privately funded, why would you make it your choice to join the segregationists? Please walk it back-back and reinstate your DEI programs.
www.theguardian.com/technology/2...
www.theguardian.com/technology/2...
February 22, 2025 at 6:03 PM
@chanzuckerberg.bsky.social why? If you're mostly privately funded, why would you make it your choice to join the segregationists? Please walk it back-back and reinstate your DEI programs.
www.theguardian.com/technology/2...
www.theguardian.com/technology/2...
Reposted by Matthew Schmitz
First post on this platform 👋. Glad to reconnect with old friends, and also learn from new contacts. Will post about intersecting themes: human evolution, genetics (esp. aDNA), neuroscience & cognition. Currently focusing on brain organoids and early developmental changes that may have had an impact
![cortical organoid [image credit: O. Leonardi, who is leading this collaborative project]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:ljcyk7tem65k7epgu5pkwuuh/bafkreico75nbiyo5zg6kzzahk5kxmcpcajygslloxkndmry2tnzr5q72pu@jpeg)
November 16, 2024 at 7:16 AM
First post on this platform 👋. Glad to reconnect with old friends, and also learn from new contacts. Will post about intersecting themes: human evolution, genetics (esp. aDNA), neuroscience & cognition. Currently focusing on brain organoids and early developmental changes that may have had an impact
Who knew hyenas were feliforms?! I always had them pegged for canidae 🧪 (phylogeny from carnivoran Wikipedia)
November 26, 2024 at 11:10 PM
Who knew hyenas were feliforms?! I always had them pegged for canidae 🧪 (phylogeny from carnivoran Wikipedia)