Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
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Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
@mtbastin.bsky.social
510 followers 970 following 59 posts
Mom | Wife | 🐎| Critical Care PharmD, PhD |PCCM PharmD @ukhealthcare | MSL- Hepatology and Critical Care @ Mallinckrodt | views are my own
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mtbastin.bsky.social
Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · Dec 12
Beautiful Kentucky 💙
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
criticalcarereviews.com
Venous excess ultrasound: A mini-review and practical guide for its application in critically ill patients

CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch
April 3, 2025 at 9:18 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
easlnews.bsky.social
🧪We are now calling for late-breaker abstracts for #EASLCongress 2025.
Take this unique opportunity to showcase your research, connect with the global liver health community, and shape the future of hepatology.
Submission deadline: 17 March 2025

www.easlcongress.eu/2025-abstrac...
March 5, 2025 at 9:37 AM
mtbastin.bsky.social
Great review for fluids+cirrhosis! 🌊

“The complex circulatory changes associated with cirrhosis and the hyperdynamic state, characterised by increased splanchnic blood volume and relative central hypovolemia, complicate fluid administration and monitoring of fluid status.”
criticalcarereviews.com Critical Care Reviews @criticalcarereviews.com · Mar 24
Today's Paper of the Day is:

Fluid resuscitation in patients with cirrhosis and sepsis: A multidisciplinary perspective

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
March 24, 2025 at 1:41 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
criticalcarereviews.com
Today's Paper of the Day is:

Fluid resuscitation in patients with cirrhosis and sepsis: A multidisciplinary perspective

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
March 24, 2025 at 10:24 AM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
iwashyna.bsky.social
Science is good for America
drsherrypagoto.bsky.social Sherry Pagoto, PhD @drsherrypagoto.bsky.social · Mar 12
New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.

That's not to mention the countless lives that biomedical research has saved.

Show me a better investment than that.
www.forbes.com/sites/michae...
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
www.forbes.com
March 13, 2025 at 1:43 AM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
mementomorty.bsky.social
Found this:

pmc.ncbi.nlm.nih.gov/articles/PMC...
Severe Measles Infection: The Spectrum of Disease in 36 Critically Ill Adult Patients
France has recently witnessed a nationwide outbreak of measles. Data on severe forms of measles in adults are lacking. We sought to describe the epidemiologic, clinical, treatment, and prognostic aspe...
pmc.ncbi.nlm.nih.gov
February 25, 2025 at 1:56 AM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
iwashyna.bsky.social
Over on LinkedIn, the head of the Executive Secretariat of the NIH -- a central part of NIH leadership 🧪🩺-- resigned with a lettter worth reading

www.linkedin.com/posts/nathan...
February 18, 2024 TO: Dr. Matthew Memoli, Acting Director, NIH CC: John Burklow, Chief of Staff, NIH Julie Berko, Director, OHR, NIH FROM: Nathaniel James Brought, Director, ES, NIH SUBJECT: Resignation Dear Dr. Memoli, On July 3, 2001, I stepped off a bus on Marine Corps Recruit Training Depot Perris Island. Scared out of my mind, I stood on a pair of freshly painted yellow footprints, raised my right hand, and recited the oath of enlistment: I, Nathaniel James Brought, do solemnly swear that I will support and defend the Constitution of the United States against all enemies, foreign and domestic; that I will bear true faith and allegiance to the same; and that I will obey the orders of the President of the United States and the orders of the officers appointed over me, according to regulations and the Uniform Code of Military Justice. So help me God. For the last 23 years, 7 months, and 15 days, I like to believe I have faithfully carried out the duties of each office to which I've been appointed in my military and civilian service to this nation. That Service has taken me from the Marine Corps to 3 different federal departments, spanned 3 continents, included service in one war zone, and has included: • For the Marine Corps and the National Security Agency, I worked on intelligence operations at the highest classification levels using bleeding edge intelligence tools to ensure America's special operators put boots-to-asses on America's enemies overseas (including commendations crediting my work for the kill or capture of dozens of terrorists), ensuring America's policy makers were able to track the movement of dangerous dual nuclear technology across international borders, and monitored the flow of terrorist financing across the international banking system. • Utilized information from all-source intelligence to ensure the continued security of America's homeland from international and domestic threats. • Worked with some of the finest lawyers in the world to ensure America's security operations were effective, while upholding the rights of all those who interacted with them. • Ensuring that America's rural communities had access to programs like rural development loans, farm aid, and that America's children wouldn't be hungry as they sat in their classrooms and tried to learn. • Most recently, and frankly most dear to my heart, working with each of you here at the National Institutes of Health to advance the future of science and medicine. Not for Americans. Not for any one group of people. But for ALL of humanity. I am unbelievably proud to be able to say that there are Americans who are alive, and terrorists who are not, because of the work I've done to serve this nation. I am proud to say that my service to this country has allowed me to ensure that my children have never faced the struggles of poverty that I grew up with. That service didn't begin because of some great altruistic impulse or drive. I didn't grow up saying "I want to do the great work that needs to be done to weave the fabric of America and ensure her people are not only safe, but healthy." Frankly, that service began because I was poor, and I was inspired. I grew up as a free lunch kid who lived in project housing. It was my fellow Americans who made sure I wasn't hungry in class and that I had enough food to excel academically the way I did. It was Americans who had more than we did that made sure I had good schools to attend where I could learn things that expanded my mind. As I approached the end of high school, I dreamed of going to college and figuring out how to make a living that would allow me to do more tha… to go to college. I knew my grades weren't good enough to compete for scholarships with kids who were as smart as me but also had private tutors and didn't have to work after class to be able to drive their brand-new cars to our school each day. So, I gave up. I nearly failed my senior year of high school with an attendance failure, even though I only needed two classes to graduate. I didn't see the point. What was the point of learning calculus? So it would be that much harder when my dream of being a brain surgeon died not because I was incapable, but because I didn't have the means to make it come true? I resigned myself to being one of the working poor. I resigned myself to needing a spinal fusion before I was 50, like my father, because he literally broke his back trying to make his dreams come true. The example of my father didn't inspire me at that time. It reminded me of the futility of trying to escape the rung of the social ladder I had been born onto. No matter how smart or "gifted and talented" I may have been, I saw no path that led me to a place where I could realize my potential. So, instead I accepted that it would be wasted. Ultimately, the reason I find myself here today, rather than in the place I saw as my only end, is because of another young man who committed to serving his country. Shamefully, I do not remember his name, but there was a young corporal from the United States Marine Corps who had been assigned as a recruiter in Reading, Pennsylvania at that time. This man spoke to me about my plans for my future during lunch one day at school. I told him I planned to do what my father had done. Work hard jobs until my body broke down, maybe start a struggling business, and try to do what I could to stay above the poverty line and off welfare. I told him I hoped to be successful enough that my kids never had to watch me use food stamps at the grocery store. It had been hard to watch my mom go through that. How sad is that? I was a smart young 18-…
February 20, 2025 at 6:43 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
ebtapper.bsky.social
journals.lww.com/hepcomm/page...

Malpractice claims in hepatology

How often
Why
And what’s the outcome
December 17, 2023 at 4:59 PM
mtbastin.bsky.social
Exciting research on personalized albumin dosing in decompensated cirrhosis! Can’t wait to see the results! 🤓
israelsenm.bsky.social Mads Israelsen @israelsenm.bsky.social · Jan 29
AlbTrial Update

🏥 70 out of 240 included

But what is AlbTrial?

AlbTrial is one of the most ambitious RCTs in the field of decompensated cirrhosis.

🔗 bmjopen.bmj.com/content/bmjo...

🧵below

Annual General Assembly in MicrobPredict #liversky #cirrhosis
February 16, 2025 at 4:11 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
natrevgastrohep.nature.com
ICYMI: New online! Drug approvals in gastroenterology and hepatology in 2024
Drug approvals in gastroenterology and hepatology in 2024
Nature Reviews Gastroenterology & Hepatology, Published online: 13 January 2025; doi:10.1038/s41575-025-01036-0Drug approvals in gastroenterology and hepatology in 2024
go.nature.com
January 19, 2025 at 12:31 PM
mtbastin.bsky.social
Winter in KY
January 24, 2025 at 2:24 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
criticalcarereviews.com
The acute phase management of traumatic spinal cord injury

CCR Journal Watch

https://criticalcarereviews.com/latest-evidence/journal-watch

Get the latest critical care literature every weekend via the CCR Newsletter - subscribe at https://criticalcarereviews.com/newsletters/subscribe
December 23, 2024 at 12:30 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
glaucomflecken.bsky.social
youtu.be/JfyECL2UtMw?... I’ve been getting a lot of new comments on old videos for some strange reason
30 Days of US Healthcare: United Healthcare Denies Everything
YouTube video by Dr. Glaucomflecken
youtu.be
December 11, 2024 at 11:02 PM
mtbastin.bsky.social
CRRT ineffective for removing lactate! Treating the underlying pathology will correct the lactatemia ⚡️
edgarvlermamd.bsky.social Edgar V. Lerma 🇵🇭 @edgarvlermamd.bsky.social · Dec 19
Although metabolic acidosis is corrected by CRRT, high-volume hemofiltration is “NOT effective” for severe lactic acidosis #Nephpearls

📌 ⬇️ lactate level during CRRT usually reflects an improvement in hemodynamic status leading to ⬆️ lactate metabolism

👉 pubmed.ncbi.nlm.nih.gov/26251702/
December 19, 2024 at 1:56 PM
mtbastin.bsky.social
Exciting development for drug discovery in MASH-cirrhosis! Always love a translational model 🐀
December 19, 2024 at 1:51 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
alexchangmd.bsky.social
Updated ADA standards of Care 2025 : for T2D + CKD - recommends use of SGLT2 OR GLP1-RA with proven CKD benefit diabetesjournals.org/care/article...
December 18, 2024 at 10:08 PM
mtbastin.bsky.social
After the rain beauty on display 🌅
December 19, 2024 at 12:03 AM
mtbastin.bsky.social
This story is 💯 % worth your time and nothing short of 🤯 🤯
mdaware.org Seth Trueger @mdaware.org · Dec 17
tragic story in the classical sense — listen to @wapplehouse.bsky.social @kavehmd.bsky.social and I discuss the Montana oncologist who settled $10.8 million for charges of fraudulent cancer charges
kavehmd.bsky.social The House of Pod @kavehmd.bsky.social · Dec 17
New Episode!

I chat with @wapplehouse.bsky.social & @mdaware.org about the recent story of a popular oncologist accused of fraud and inappropriate treatment with chemotherapy.

iTunes: tinyurl.com/2s475zp8
Spotify: tinyurl.com/4ej5ky56
December 17, 2024 at 4:53 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
saltnshekar.bsky.social
What an exciting time! 🐷✨ @nyunephro.bsky.social
www.npr.org/sections/sho...
A transplanted pig kidney offers a grandmother hope for life without dialysis
The patient was in kidney failure and her immune system would reject a human organ. Scientists hope genetically modified pig organs prove safe and will alleviate the organ shortage and save lives.
www.npr.org
December 17, 2024 at 3:59 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
pauleric70.bsky.social
Bryce Canyon National Park at sunrise 🇺🇲
Stunning capture ✨🧡✨🧡✨🧡✨
December 16, 2024 at 6:59 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
asnkidney.bsky.social
🚨 Now Hiring: ASN is seeking an Editor-in-Chief for Kidney360 🌟 Lead innovation in nephrology, drive research, and shape the future of kidney care. Apply by Jan 31, 2025. Apply today.

👉 bit.ly/Kidney360EIC

#Kidney360 #Nephrology #JobAlert
December 16, 2024 at 9:48 PM
mtbastin.bsky.social
#Pharmsky
mtbastin.bsky.social Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · Dec 16
It’s the derivation of this equation (from Josh’s link to the Matzke nonogram paper) which plots vancomycin Cl (ke-1) to CrCL..

Ke=0.00083(CrCL) + 0.0044

Also need to advocate this type of work is a clinical pharmacists bread and butter, and one of the many reasons we need Pharmds at the bedside.
December 16, 2024 at 9:17 PM
Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP
mtbastin.bsky.social
It’s the derivation of this equation (from Josh’s link to the Matzke nonogram paper) which plots vancomycin Cl (ke-1) to CrCL..

Ke=0.00083(CrCL) + 0.0044

Also need to advocate this type of work is a clinical pharmacists bread and butter, and one of the many reasons we need Pharmds at the bedside.
December 16, 2024 at 7:01 PM
mtbastin.bsky.social
Some more depressing US quality of lifespan data to start your Monday.. ☹️
meganranney.bsky.social Megan Ranney MD MPH @meganranney.bsky.social · Dec 16
An interesting study of gaps between “healthspan” (yrs of healthy life) & “lifespan” across the globe.

Takeaway: the US has amongst the largest gaps, despite relatively low lifespan.

And women in the US have even bigger gaps. 🛟🩺🧪😷

jamanetwork.com/journals/jam...
December 16, 2024 at 1:37 PM
mtbastin.bsky.social
Love to see this work of sex differences in outcome response being done. But it needs to happen as part of the primary hypothesis and not in retrospect.. ✨ #womenshealth
December 16, 2024 at 1:33 PM