DECISION Horizon2020
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decision4liver.bsky.social
DECISION Horizon2020
@decision4liver.bsky.social
DECISION is an international, EU-funded research project on decompensated cirrhosis to identify new combinatorial therapies based on systems approaches.
🌐 https://decision-for-liver.eu/

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Hi! We're the DECISION consortium, an EU-funded research project striving to better understand the #pathophysiology of decompensated #cirrhosis leading to acute-on-chronic liver failure ( #ACLF ) at the systems level.
We're 21 institutions form 10 European countries 💪
📺New masterclass!
‘Data repositories & their access and publication rights’ covers the history of databases, an overview of repositories used in DECISION & provides a hands-on recipe on how to make the best out of different types of data
⏯️ youtu.be/aoA0WC1yaqs

#bioinformatics
Data repositories and their access and publication rights | Masterclass in bioinformatics
YouTube video by concentris research management
youtu.be
January 15, 2026 at 9:21 AM
DECISION's Year-in-Review2️⃣0️⃣2️⃣5️⃣
💙Networking session at EASL2025
🩵New publication on maladaptive emergency granulopoiesis
💙Met at Final General Assembly in Bologna
🩵Released 3 high-level lectures

We look forward to continuing our collaboration in 2026, finishing strong, and maximizing our impact 💪
December 16, 2025 at 12:47 PM
New keynote out now!
🌟 Prof. Rubén Francés explains how LSECtin shapes immune tolerance and inflammation in advanced chronic liver disease.
Watch here: www.youtube.com/watch?v=pY9H...

#LiverSky #cirrhosis #inflammation
The Role of LSECtin in Regulating Inflammation in Advanced Chronic Liver Disease | DECISION Keynote
YouTube video by concentris research management
www.youtube.com
December 9, 2025 at 9:31 AM
New DECISION study in @jhepatology.bsky.social: maladaptive emergency granulopoiesis predicts poor outcomes in acutely #decompensatedcirrhosis.
This could guide early identification and novel therapies.
www.sciencedirect.com/science/arti...

#ACLF #LiverSky #Hepatology @easlnews.bsky.social
Maladaptive emergency granulopoiesis predicts poor outcomes in patients hospitalized with decompensated cirrhosis
Whether analysis of whole blood transcriptome assessed on admission of patients with acutely decompensated cirrhosis (ADC) without acute-on-chronic li…
www.sciencedirect.com
November 27, 2025 at 9:29 AM
That’s a wrap on our final DECISION GA!

From COMBAT & PROSPECT updates to forward-looking discussions and feedback, we’re proud of our shared achievements and motivated to keep advancing ACLF & decompensated cirrhosis research together.

#LiverSky
October 10, 2025 at 10:31 AM
Our final GA is a look back and forward - from major scientific milestones to future discoveries!
After a keynote by Prof. Rubén Francés, partners shared results on omics integration, biomarkers & systems medicine - and closed today with a masterclass on data repositories. #cirrhosis
October 9, 2025 at 2:47 PM
Next week: the final DECISION General Assembly in Madrid! 🎉
Celebrating 5+ years of science, collaboration, & results
@rautoupe.bsky.social  @concentris.bsky.social 
@navarrabiomed.bsky.social 
@bioeticayderecho.bsky.social 
@medblab.bsky.social 
@europeliver.bsky.social 
@easlnews.bsky.social et al
October 1, 2025 at 8:02 AM
The latest DECISION Masterclass is live!
💡 Clinical Bioinformatics – It’s More Than Pressing a Button with Núria Planell, Cristina Sanchez & David Gomez-Cabrero.

Watch here: https://youtu.be/UBm1_JGhw6M

#Bioinformatics #ClinicalResearch #ACLF
September 24, 2025 at 8:02 AM
Today is #WorldHepatitisDay! We spotlight two DECISION partners deeply committed to #liverhealth:
🔬 @easlnews.bsky.social – advancing #hepatology research
🧡 @europeliver.bsky.social – amplifying the voice of liver patients
Together, we work toward a healthier future beyond ACLF.

#Cirrhosis
July 28, 2025 at 8:55 AM
🎥 New keynote online!
Prof. Richard Moreau, Director of #EFCLIF, explores immune dysfunction in AD & #ACLF and suggests a common mechanism behind inflammation & immune deficiency.
Watch now 👉 https://youtu.be/KWoUbTsNjQM 
#LiverSky #Hepatology
June 26, 2025 at 11:20 AM
🎉 Exciting news: We’ve surpassed 500 followers on @linkedin.com!
Follow us there for updates on trials, science, and more 👉 www.linkedin.com/company/deci...

#ClinicalResearch #DECISIONproject
June 17, 2025 at 12:14 PM
Consider joining this event by @a-tango.bsky.social and @crowdhelix.com!
"Industrial Perspective on Drug Development Challenges for Clinical Trials"

📅 4th June 2025
🕚 11:00 am CEST / 🕙 10:00 am BST

Register via this link: inevent.uk/en/Crowdheli...
June 2, 2025 at 7:45 AM
It’s #ClinicalTrialsDay! At DECISION, we’re proud of our COMBAT & PROSPECT trials advancing care in decompensated cirrhosis.
💡COMBAT Q&A videos in multiple languages help engage patients ➡️ www.youtube.com/playlist?lis...

Thanks to all who make our trials possible! #LiverResearch
May 20, 2025 at 6:52 AM
Reposted by DECISION Horizon2020
#PosterTour today at #EASLCongress 2025:
All our 3 Horizon2020 #LiverResearch projects in 1 session!

Topic: #Cirrhosis & #PortalHypertension
Chair: Maria Papp

💡 Big moments:

#AMMON-OHE model for post-#TIPS #encephalopathy (Rajiv Jalan)

#Terlipressin response in AKI-HRS w/ CKD (Frank Uschner)
May 10, 2025 at 12:04 PM
Clinical trajectories of patients with cirrhosis and ascites receiving long-term albumin
#POSTER SAT-145-YI by Enrico Pompili (UNIBO) proposes a personalized management approach for patients with cirrhosis and ascites, based on real-world data from long-term albumin therapy. #EASL2025
May 10, 2025 at 10:58 AM
🩺 Impact of diabetes mellitus on clinical outcomes in patients with acutely decompensated cirrhosis

#E_POSTER SAT-184-YI by Mimma Bonomo (UNITO) explores how coexisting diabetes mellitus affects prognosis in patients hospitalized with acute decompensation of cirrhosis.

#EASL2025
May 10, 2025 at 10:45 AM
🦠The recovery failure of fecal microbiota diversity in patients after liver transplant is associated with a complicated postoperative course

#POSTER SAT-518 by @beccsipollsi.bsky.social from @rwth.bsky.social at #EASL2025

@brunslab.bsky.social
@easlnews.bsky.social
May 10, 2025 at 10:35 AM
🧪 Acute kidney disease in acutely decompensated cirrhosis: impact on clinical outcomes

#POSTER SAT-122-YI by Alberto Calleri (UNITO) examines how acute kidney disease affects outcomes in patients with acutely decompensated cirrhosis.

📅 Presented at #EASLCongress | #EASL2025
@easlnews.bsky.social
May 10, 2025 at 10:20 AM
❤️ Cardiac performance is impaired in patients with proven alcohol-related hepatitis and predicts 3-month mortality in this patient population

#POSTER SAT-503-YI by Pierre-Emmanuel Rautou (@inserm.fr, APHP, EF CLIF)

📅 Presented at the #EASLCongress | #EASL2025
@easlnews.bsky.social
May 10, 2025 at 10:07 AM
Back in the Abstract Session: Theresa Wirtz presents her scRNA-seq work on monocyte subsets and ACLF risk.

@rwth.bsky.social
@brunslab.bsky.social
@easlnews.bsky.social

#Cirrhosis #ACLF #EASL2025"
May 10, 2025 at 8:58 AM
Estefania Huergo presents methylation data in AD patients, selected as best Young Investigator abstract in Basic Science at #EASL2025 - Congrats! 🎉
@navarrabiomed.bsky.social
@easlnews.bsky.social
#Epigenetics #LiverResearch
May 10, 2025 at 8:42 AM
Javier Fernandez (FCRB) is giving the hepatologist perspective on management of MDR infections in cirrhosis as part of the EASL/ESCMID Symposium: MDR infections - a challenge in decompensated cirrhosis at #EASL2025

#LiverDisease #Cirrhosis #Hepatology @easlnews.bsky.social
May 10, 2025 at 7:13 AM
Is the etiological work-up of #PSVD a one-size-fits-all?

DECISION consortium member Lucile Moga from APHP takes part in EASL/ VALDIG's session on "Do's and Don'ts in the management of Porto-Sinusoidal Vascular Disease".

#EASLCongress #EASL2025 #LiverResearch
@easlnews.bsky.social
May 10, 2025 at 7:00 AM
How do you build&lead a successful research team?
The next generation of PIs learned straight from the best in today's workshop “How to Start a Research Group: From Postdoc to PI" as @rautoupe.bsky.social shared practical insights on building&maintaining a high-performing team.
@inserm.fr #EASL2025
May 9, 2025 at 4:33 PM