DECISION Horizon2020
@decision4liver.bsky.social
DECISION is an international, EU-funded research project on decompensated cirrhosis to identify new combinatorial therapies based on systems approaches.
🌐 https://decision-for-liver.eu/
🌐 https://decision-for-liver.eu/
Pinned
Hi! We're the DECISION consortium, an EU-funded research project striving to better understand the #pathophysiology of decompensated #cirrhosis leading to acute-on-chronic liver failure ( #ACLF ) at the systems level.
We're 21 institutions form 10 European countries 💪
That’s a wrap on our final DECISION GA!
From COMBAT & PROSPECT updates to forward-looking discussions and feedback, we’re proud of our shared achievements and motivated to keep advancing ACLF & decompensated cirrhosis research together.
#LiverSky
From COMBAT & PROSPECT updates to forward-looking discussions and feedback, we’re proud of our shared achievements and motivated to keep advancing ACLF & decompensated cirrhosis research together.
#LiverSky
October 10, 2025 at 10:31 AM
That’s a wrap on our final DECISION GA!
From COMBAT & PROSPECT updates to forward-looking discussions and feedback, we’re proud of our shared achievements and motivated to keep advancing ACLF & decompensated cirrhosis research together.
#LiverSky
From COMBAT & PROSPECT updates to forward-looking discussions and feedback, we’re proud of our shared achievements and motivated to keep advancing ACLF & decompensated cirrhosis research together.
#LiverSky
Our final GA is a look back and forward - from major scientific milestones to future discoveries!
After a keynote by Prof. Rubén Francés, partners shared results on omics integration, biomarkers & systems medicine - and closed today with a masterclass on data repositories. #cirrhosis
After a keynote by Prof. Rubén Francés, partners shared results on omics integration, biomarkers & systems medicine - and closed today with a masterclass on data repositories. #cirrhosis
October 9, 2025 at 2:47 PM
Our final GA is a look back and forward - from major scientific milestones to future discoveries!
After a keynote by Prof. Rubén Francés, partners shared results on omics integration, biomarkers & systems medicine - and closed today with a masterclass on data repositories. #cirrhosis
After a keynote by Prof. Rubén Francés, partners shared results on omics integration, biomarkers & systems medicine - and closed today with a masterclass on data repositories. #cirrhosis
Next week: the final DECISION General Assembly in Madrid! 🎉
Celebrating 5+ years of science, collaboration, & results
@rautoupe.bsky.social @concentris.bsky.social
@navarrabiomed.bsky.social
@bioeticayderecho.bsky.social
@medblab.bsky.social
@europeliver.bsky.social
@easlnews.bsky.social et al
Celebrating 5+ years of science, collaboration, & results
@rautoupe.bsky.social @concentris.bsky.social
@navarrabiomed.bsky.social
@bioeticayderecho.bsky.social
@medblab.bsky.social
@europeliver.bsky.social
@easlnews.bsky.social et al
October 1, 2025 at 8:02 AM
Next week: the final DECISION General Assembly in Madrid! 🎉
Celebrating 5+ years of science, collaboration, & results
@rautoupe.bsky.social @concentris.bsky.social
@navarrabiomed.bsky.social
@bioeticayderecho.bsky.social
@medblab.bsky.social
@europeliver.bsky.social
@easlnews.bsky.social et al
Celebrating 5+ years of science, collaboration, & results
@rautoupe.bsky.social @concentris.bsky.social
@navarrabiomed.bsky.social
@bioeticayderecho.bsky.social
@medblab.bsky.social
@europeliver.bsky.social
@easlnews.bsky.social et al
The latest DECISION Masterclass is live!
💡 Clinical Bioinformatics – It’s More Than Pressing a Button with Núria Planell, Cristina Sanchez & David Gomez-Cabrero.
Watch here: https://youtu.be/UBm1_JGhw6M
#Bioinformatics #ClinicalResearch #ACLF
💡 Clinical Bioinformatics – It’s More Than Pressing a Button with Núria Planell, Cristina Sanchez & David Gomez-Cabrero.
Watch here: https://youtu.be/UBm1_JGhw6M
#Bioinformatics #ClinicalResearch #ACLF
September 24, 2025 at 8:02 AM
The latest DECISION Masterclass is live!
💡 Clinical Bioinformatics – It’s More Than Pressing a Button with Núria Planell, Cristina Sanchez & David Gomez-Cabrero.
Watch here: https://youtu.be/UBm1_JGhw6M
#Bioinformatics #ClinicalResearch #ACLF
💡 Clinical Bioinformatics – It’s More Than Pressing a Button with Núria Planell, Cristina Sanchez & David Gomez-Cabrero.
Watch here: https://youtu.be/UBm1_JGhw6M
#Bioinformatics #ClinicalResearch #ACLF
Today is #WorldHepatitisDay! We spotlight two DECISION partners deeply committed to #liverhealth:
🔬 @easlnews.bsky.social – advancing #hepatology research
🧡 @europeliver.bsky.social – amplifying the voice of liver patients
Together, we work toward a healthier future beyond ACLF.
#Cirrhosis
🔬 @easlnews.bsky.social – advancing #hepatology research
🧡 @europeliver.bsky.social – amplifying the voice of liver patients
Together, we work toward a healthier future beyond ACLF.
#Cirrhosis
July 28, 2025 at 8:55 AM
Today is #WorldHepatitisDay! We spotlight two DECISION partners deeply committed to #liverhealth:
🔬 @easlnews.bsky.social – advancing #hepatology research
🧡 @europeliver.bsky.social – amplifying the voice of liver patients
Together, we work toward a healthier future beyond ACLF.
#Cirrhosis
🔬 @easlnews.bsky.social – advancing #hepatology research
🧡 @europeliver.bsky.social – amplifying the voice of liver patients
Together, we work toward a healthier future beyond ACLF.
#Cirrhosis
🔥 We’ve hit 50% recruitment in the #COMBATtrial!
Huge thanks to all involved!💙
@rautoupe.bsky.social @hopitalbeaujon.bsky.social @hospitalclinic.bsky.social @rwth.bsky.social @uni-muenster.de @brunslab.bsky.social @medblab.bsky.social @frankuschner.bsky.social
#LiverSky #ClinicalTrial
Huge thanks to all involved!💙
@rautoupe.bsky.social @hopitalbeaujon.bsky.social @hospitalclinic.bsky.social @rwth.bsky.social @uni-muenster.de @brunslab.bsky.social @medblab.bsky.social @frankuschner.bsky.social
#LiverSky #ClinicalTrial
June 30, 2025 at 3:55 PM
🔥 We’ve hit 50% recruitment in the #COMBATtrial!
Huge thanks to all involved!💙
@rautoupe.bsky.social @hopitalbeaujon.bsky.social @hospitalclinic.bsky.social @rwth.bsky.social @uni-muenster.de @brunslab.bsky.social @medblab.bsky.social @frankuschner.bsky.social
#LiverSky #ClinicalTrial
Huge thanks to all involved!💙
@rautoupe.bsky.social @hopitalbeaujon.bsky.social @hospitalclinic.bsky.social @rwth.bsky.social @uni-muenster.de @brunslab.bsky.social @medblab.bsky.social @frankuschner.bsky.social
#LiverSky #ClinicalTrial
🎥 New keynote online!
Prof. Richard Moreau, Director of #EFCLIF, explores immune dysfunction in AD & #ACLF and suggests a common mechanism behind inflammation & immune deficiency.
Watch now 👉 https://youtu.be/KWoUbTsNjQM
#LiverSky #Hepatology
Prof. Richard Moreau, Director of #EFCLIF, explores immune dysfunction in AD & #ACLF and suggests a common mechanism behind inflammation & immune deficiency.
Watch now 👉 https://youtu.be/KWoUbTsNjQM
#LiverSky #Hepatology
June 26, 2025 at 11:20 AM
🎥 New keynote online!
Prof. Richard Moreau, Director of #EFCLIF, explores immune dysfunction in AD & #ACLF and suggests a common mechanism behind inflammation & immune deficiency.
Watch now 👉 https://youtu.be/KWoUbTsNjQM
#LiverSky #Hepatology
Prof. Richard Moreau, Director of #EFCLIF, explores immune dysfunction in AD & #ACLF and suggests a common mechanism behind inflammation & immune deficiency.
Watch now 👉 https://youtu.be/KWoUbTsNjQM
#LiverSky #Hepatology
🎉 Exciting news: We’ve surpassed 500 followers on @linkedin.com!
Follow us there for updates on trials, science, and more 👉 www.linkedin.com/company/deci...
#ClinicalResearch #DECISIONproject
Follow us there for updates on trials, science, and more 👉 www.linkedin.com/company/deci...
#ClinicalResearch #DECISIONproject
June 17, 2025 at 12:14 PM
🎉 Exciting news: We’ve surpassed 500 followers on @linkedin.com!
Follow us there for updates on trials, science, and more 👉 www.linkedin.com/company/deci...
#ClinicalResearch #DECISIONproject
Follow us there for updates on trials, science, and more 👉 www.linkedin.com/company/deci...
#ClinicalResearch #DECISIONproject
Consider joining this event by @a-tango.bsky.social and @crowdhelix.com!
"Industrial Perspective on Drug Development Challenges for Clinical Trials"
📅 4th June 2025
🕚 11:00 am CEST / 🕙 10:00 am BST
Register via this link: inevent.uk/en/Crowdheli...
"Industrial Perspective on Drug Development Challenges for Clinical Trials"
📅 4th June 2025
🕚 11:00 am CEST / 🕙 10:00 am BST
Register via this link: inevent.uk/en/Crowdheli...
June 2, 2025 at 7:45 AM
Consider joining this event by @a-tango.bsky.social and @crowdhelix.com!
"Industrial Perspective on Drug Development Challenges for Clinical Trials"
📅 4th June 2025
🕚 11:00 am CEST / 🕙 10:00 am BST
Register via this link: inevent.uk/en/Crowdheli...
"Industrial Perspective on Drug Development Challenges for Clinical Trials"
📅 4th June 2025
🕚 11:00 am CEST / 🕙 10:00 am BST
Register via this link: inevent.uk/en/Crowdheli...
It’s #ClinicalTrialsDay! At DECISION, we’re proud of our COMBAT & PROSPECT trials advancing care in decompensated cirrhosis.
💡COMBAT Q&A videos in multiple languages help engage patients ➡️ www.youtube.com/playlist?lis...
Thanks to all who make our trials possible! #LiverResearch
💡COMBAT Q&A videos in multiple languages help engage patients ➡️ www.youtube.com/playlist?lis...
Thanks to all who make our trials possible! #LiverResearch
May 20, 2025 at 6:52 AM
It’s #ClinicalTrialsDay! At DECISION, we’re proud of our COMBAT & PROSPECT trials advancing care in decompensated cirrhosis.
💡COMBAT Q&A videos in multiple languages help engage patients ➡️ www.youtube.com/playlist?lis...
Thanks to all who make our trials possible! #LiverResearch
💡COMBAT Q&A videos in multiple languages help engage patients ➡️ www.youtube.com/playlist?lis...
Thanks to all who make our trials possible! #LiverResearch
Reposted by DECISION Horizon2020
✨ #PosterTour today at #EASLCongress 2025:
All our 3 Horizon2020 #LiverResearch projects in 1 session!
Topic: #Cirrhosis & #PortalHypertension
Chair: Maria Papp
💡 Big moments:
#AMMON-OHE model for post-#TIPS #encephalopathy (Rajiv Jalan)
#Terlipressin response in AKI-HRS w/ CKD (Frank Uschner)
All our 3 Horizon2020 #LiverResearch projects in 1 session!
Topic: #Cirrhosis & #PortalHypertension
Chair: Maria Papp
💡 Big moments:
#AMMON-OHE model for post-#TIPS #encephalopathy (Rajiv Jalan)
#Terlipressin response in AKI-HRS w/ CKD (Frank Uschner)
May 10, 2025 at 12:04 PM
✨ #PosterTour today at #EASLCongress 2025:
All our 3 Horizon2020 #LiverResearch projects in 1 session!
Topic: #Cirrhosis & #PortalHypertension
Chair: Maria Papp
💡 Big moments:
#AMMON-OHE model for post-#TIPS #encephalopathy (Rajiv Jalan)
#Terlipressin response in AKI-HRS w/ CKD (Frank Uschner)
All our 3 Horizon2020 #LiverResearch projects in 1 session!
Topic: #Cirrhosis & #PortalHypertension
Chair: Maria Papp
💡 Big moments:
#AMMON-OHE model for post-#TIPS #encephalopathy (Rajiv Jalan)
#Terlipressin response in AKI-HRS w/ CKD (Frank Uschner)
Clinical trajectories of patients with cirrhosis and ascites receiving long-term albumin
#POSTER SAT-145-YI by Enrico Pompili (UNIBO) proposes a personalized management approach for patients with cirrhosis and ascites, based on real-world data from long-term albumin therapy. #EASL2025
#POSTER SAT-145-YI by Enrico Pompili (UNIBO) proposes a personalized management approach for patients with cirrhosis and ascites, based on real-world data from long-term albumin therapy. #EASL2025
May 10, 2025 at 10:58 AM
🩺 Impact of diabetes mellitus on clinical outcomes in patients with acutely decompensated cirrhosis
#E_POSTER SAT-184-YI by Mimma Bonomo (UNITO) explores how coexisting diabetes mellitus affects prognosis in patients hospitalized with acute decompensation of cirrhosis.
#EASL2025
#E_POSTER SAT-184-YI by Mimma Bonomo (UNITO) explores how coexisting diabetes mellitus affects prognosis in patients hospitalized with acute decompensation of cirrhosis.
#EASL2025
May 10, 2025 at 10:45 AM
🦠The recovery failure of fecal microbiota diversity in patients after liver transplant is associated with a complicated postoperative course
#POSTER SAT-518 by @beccsipollsi.bsky.social from @rwth.bsky.social at #EASL2025
@brunslab.bsky.social
@easlnews.bsky.social
#POSTER SAT-518 by @beccsipollsi.bsky.social from @rwth.bsky.social at #EASL2025
@brunslab.bsky.social
@easlnews.bsky.social
May 10, 2025 at 10:35 AM
🦠The recovery failure of fecal microbiota diversity in patients after liver transplant is associated with a complicated postoperative course
#POSTER SAT-518 by @beccsipollsi.bsky.social from @rwth.bsky.social at #EASL2025
@brunslab.bsky.social
@easlnews.bsky.social
#POSTER SAT-518 by @beccsipollsi.bsky.social from @rwth.bsky.social at #EASL2025
@brunslab.bsky.social
@easlnews.bsky.social
🧪 Acute kidney disease in acutely decompensated cirrhosis: impact on clinical outcomes
#POSTER SAT-122-YI by Alberto Calleri (UNITO) examines how acute kidney disease affects outcomes in patients with acutely decompensated cirrhosis.
📅 Presented at #EASLCongress | #EASL2025
@easlnews.bsky.social
#POSTER SAT-122-YI by Alberto Calleri (UNITO) examines how acute kidney disease affects outcomes in patients with acutely decompensated cirrhosis.
📅 Presented at #EASLCongress | #EASL2025
@easlnews.bsky.social
May 10, 2025 at 10:20 AM
🧪 Acute kidney disease in acutely decompensated cirrhosis: impact on clinical outcomes
#POSTER SAT-122-YI by Alberto Calleri (UNITO) examines how acute kidney disease affects outcomes in patients with acutely decompensated cirrhosis.
📅 Presented at #EASLCongress | #EASL2025
@easlnews.bsky.social
#POSTER SAT-122-YI by Alberto Calleri (UNITO) examines how acute kidney disease affects outcomes in patients with acutely decompensated cirrhosis.
📅 Presented at #EASLCongress | #EASL2025
@easlnews.bsky.social
❤️ Cardiac performance is impaired in patients with proven alcohol-related hepatitis and predicts 3-month mortality in this patient population
#POSTER SAT-503-YI by Pierre-Emmanuel Rautou (@inserm.fr, APHP, EF CLIF)
📅 Presented at the #EASLCongress | #EASL2025
@easlnews.bsky.social
#POSTER SAT-503-YI by Pierre-Emmanuel Rautou (@inserm.fr, APHP, EF CLIF)
📅 Presented at the #EASLCongress | #EASL2025
@easlnews.bsky.social
May 10, 2025 at 10:07 AM
❤️ Cardiac performance is impaired in patients with proven alcohol-related hepatitis and predicts 3-month mortality in this patient population
#POSTER SAT-503-YI by Pierre-Emmanuel Rautou (@inserm.fr, APHP, EF CLIF)
📅 Presented at the #EASLCongress | #EASL2025
@easlnews.bsky.social
#POSTER SAT-503-YI by Pierre-Emmanuel Rautou (@inserm.fr, APHP, EF CLIF)
📅 Presented at the #EASLCongress | #EASL2025
@easlnews.bsky.social
Back in the Abstract Session: Theresa Wirtz presents her scRNA-seq work on monocyte subsets and ACLF risk.
@rwth.bsky.social
@brunslab.bsky.social
@easlnews.bsky.social
#Cirrhosis #ACLF #EASL2025"
@rwth.bsky.social
@brunslab.bsky.social
@easlnews.bsky.social
#Cirrhosis #ACLF #EASL2025"
May 10, 2025 at 8:58 AM
Back in the Abstract Session: Theresa Wirtz presents her scRNA-seq work on monocyte subsets and ACLF risk.
@rwth.bsky.social
@brunslab.bsky.social
@easlnews.bsky.social
#Cirrhosis #ACLF #EASL2025"
@rwth.bsky.social
@brunslab.bsky.social
@easlnews.bsky.social
#Cirrhosis #ACLF #EASL2025"
Estefania Huergo presents methylation data in AD patients, selected as best Young Investigator abstract in Basic Science at #EASL2025 - Congrats! 🎉
@navarrabiomed.bsky.social
@easlnews.bsky.social
#Epigenetics #LiverResearch
@navarrabiomed.bsky.social
@easlnews.bsky.social
#Epigenetics #LiverResearch
May 10, 2025 at 8:42 AM
Estefania Huergo presents methylation data in AD patients, selected as best Young Investigator abstract in Basic Science at #EASL2025 - Congrats! 🎉
@navarrabiomed.bsky.social
@easlnews.bsky.social
#Epigenetics #LiverResearch
@navarrabiomed.bsky.social
@easlnews.bsky.social
#Epigenetics #LiverResearch
Javier Fernandez (FCRB) is giving the hepatologist perspective on management of MDR infections in cirrhosis as part of the EASL/ESCMID Symposium: MDR infections - a challenge in decompensated cirrhosis at #EASL2025
#LiverDisease #Cirrhosis #Hepatology @easlnews.bsky.social
#LiverDisease #Cirrhosis #Hepatology @easlnews.bsky.social
May 10, 2025 at 7:13 AM
Javier Fernandez (FCRB) is giving the hepatologist perspective on management of MDR infections in cirrhosis as part of the EASL/ESCMID Symposium: MDR infections - a challenge in decompensated cirrhosis at #EASL2025
#LiverDisease #Cirrhosis #Hepatology @easlnews.bsky.social
#LiverDisease #Cirrhosis #Hepatology @easlnews.bsky.social
Is the etiological work-up of #PSVD a one-size-fits-all?
DECISION consortium member Lucile Moga from APHP takes part in EASL/ VALDIG's session on "Do's and Don'ts in the management of Porto-Sinusoidal Vascular Disease".
#EASLCongress #EASL2025 #LiverResearch
@easlnews.bsky.social
DECISION consortium member Lucile Moga from APHP takes part in EASL/ VALDIG's session on "Do's and Don'ts in the management of Porto-Sinusoidal Vascular Disease".
#EASLCongress #EASL2025 #LiverResearch
@easlnews.bsky.social
May 10, 2025 at 7:00 AM
Is the etiological work-up of #PSVD a one-size-fits-all?
DECISION consortium member Lucile Moga from APHP takes part in EASL/ VALDIG's session on "Do's and Don'ts in the management of Porto-Sinusoidal Vascular Disease".
#EASLCongress #EASL2025 #LiverResearch
@easlnews.bsky.social
DECISION consortium member Lucile Moga from APHP takes part in EASL/ VALDIG's session on "Do's and Don'ts in the management of Porto-Sinusoidal Vascular Disease".
#EASLCongress #EASL2025 #LiverResearch
@easlnews.bsky.social
How do you build&lead a successful research team?
The next generation of PIs learned straight from the best in today's workshop “How to Start a Research Group: From Postdoc to PI" as @rautoupe.bsky.social shared practical insights on building&maintaining a high-performing team.
@inserm.fr #EASL2025
The next generation of PIs learned straight from the best in today's workshop “How to Start a Research Group: From Postdoc to PI" as @rautoupe.bsky.social shared practical insights on building&maintaining a high-performing team.
@inserm.fr #EASL2025
May 9, 2025 at 4:33 PM
How do you build&lead a successful research team?
The next generation of PIs learned straight from the best in today's workshop “How to Start a Research Group: From Postdoc to PI" as @rautoupe.bsky.social shared practical insights on building&maintaining a high-performing team.
@inserm.fr #EASL2025
The next generation of PIs learned straight from the best in today's workshop “How to Start a Research Group: From Postdoc to PI" as @rautoupe.bsky.social shared practical insights on building&maintaining a high-performing team.
@inserm.fr #EASL2025
DECISION consortium member Sophie Lotersztajn from the French research institute @inserm.fr at a late-afternoon abstract session today at #EASLCongress in Amsterdam, the Netherlands, about #fibrosis, #hepatocyte and #liver #regeneration. 🩺
#EASL2025 @easlnews.bsky.social
#EASL2025 @easlnews.bsky.social
May 9, 2025 at 3:13 PM
DECISION consortium member Sophie Lotersztajn from the French research institute @inserm.fr at a late-afternoon abstract session today at #EASLCongress in Amsterdam, the Netherlands, about #fibrosis, #hepatocyte and #liver #regeneration. 🩺
#EASL2025 @easlnews.bsky.social
#EASL2025 @easlnews.bsky.social
🔬 #POSTER FRI-222 by Thierry Gustot (EF CLIF) proposes one-week criteria to assess the appropriateness of continuing intensive care in ACLF patients who are not candidates for liver transplantation.
#EASL2025 @easlnews.bsky.social
#EASL2025 @easlnews.bsky.social
May 9, 2025 at 11:46 AM
🔬 #POSTER FRI-222 by Thierry Gustot (EF CLIF) proposes one-week criteria to assess the appropriateness of continuing intensive care in ACLF patients who are not candidates for liver transplantation.
#EASL2025 @easlnews.bsky.social
#EASL2025 @easlnews.bsky.social
📊 Fibroblast growth factor 19 (FGF-19) predicts transplant free-survival in critically ill patients with acute-onchronic liver failure
#POSTER FRI-199 by @beccsipollsi.bsky.social
📅 #EASLCongress | #EASL2025
@easlnews.bsky.social
#POSTER FRI-199 by @beccsipollsi.bsky.social
📅 #EASLCongress | #EASL2025
@easlnews.bsky.social
May 9, 2025 at 10:41 AM
📊 Fibroblast growth factor 19 (FGF-19) predicts transplant free-survival in critically ill patients with acute-onchronic liver failure
#POSTER FRI-199 by @beccsipollsi.bsky.social
📅 #EASLCongress | #EASL2025
@easlnews.bsky.social
#POSTER FRI-199 by @beccsipollsi.bsky.social
📅 #EASLCongress | #EASL2025
@easlnews.bsky.social
🧊 Hypothermic oxygenated machine perfusion (HOPE) treatment prior to organ transplant alters key immune modulators in patients receiving liver transplantation
#POSTER FRI-495-YI by @beccsipollsi.bsky.social
📅 #EASLCongress | #EASL2025
@brunslab.bsky.social @easlnews.bsky.social
#POSTER FRI-495-YI by @beccsipollsi.bsky.social
📅 #EASLCongress | #EASL2025
@brunslab.bsky.social @easlnews.bsky.social
May 9, 2025 at 10:34 AM
🧊 Hypothermic oxygenated machine perfusion (HOPE) treatment prior to organ transplant alters key immune modulators in patients receiving liver transplantation
#POSTER FRI-495-YI by @beccsipollsi.bsky.social
📅 #EASLCongress | #EASL2025
@brunslab.bsky.social @easlnews.bsky.social
#POSTER FRI-495-YI by @beccsipollsi.bsky.social
📅 #EASLCongress | #EASL2025
@brunslab.bsky.social @easlnews.bsky.social