Marco Podobnik
@mpodobnik.bsky.social
Walter Benjamin Fellow at @armilabs.bsky.social Melbourne interested in developmental, regenerative and evolutionary biology. @mpi-bio-fml.bsky.social alumnus. https://marcopodobnik.wordpress.com/
Pinned
Marco Podobnik
@mpodobnik.bsky.social
· Oct 20
Happy to have contributed to this big story. We present new genome assemblies, genus-wide complementation and allele-specific expression analyses in hybrids between zebrafish and closely related Danio species with divergent pigment patterns. A vertebrate model genus for basic comparative biology.
Reposted by Marco Podobnik
New paper alert!🤩Super proud that our story led by superstar postdocs @liujinghui.bsky.social and @nerlielisa.bsky.social is finally out! We found how electrical signals are key for promoting organ regenerative growth!!! A thread 🧵https://www.science.org/doi/10.1126/sciadv.aec0687
Injury-induced electrochemical coupling triggers organ growth
Organ repair and growth rely on coupling tissue-wide membrane depolarization with intracellular proliferative signaling.
www.science.org
February 5, 2026 at 9:33 AM
New paper alert!🤩Super proud that our story led by superstar postdocs @liujinghui.bsky.social and @nerlielisa.bsky.social is finally out! We found how electrical signals are key for promoting organ regenerative growth!!! A thread 🧵https://www.science.org/doi/10.1126/sciadv.aec0687
If you are interested in a PhD on protein science in a very pretty part of Southern Germany, consider this amazing opportunity to work with @hadeerelhabashy.bsky.social.
📣 Call for a PhD position in Artificial Intelligence for Protein Science
Details of the call can be found at the following link:
www.uni-bayreuth.de/job-vacancy-...
Please feel free to spread the word!
Details of the call can be found at the following link:
www.uni-bayreuth.de/job-vacancy-...
Please feel free to spread the word!
January 1, 2026 at 10:25 AM
If you are interested in a PhD on protein science in a very pretty part of Southern Germany, consider this amazing opportunity to work with @hadeerelhabashy.bsky.social.
Reposted by Marco Podobnik
Can we tune a plant’s epigenetic toolkit to disrupt plant homeostasis in ways that enable phenotypic innovation?
🌱Check out our new Opinion Paper with @thanvisrikant.bsky.social discussing this topic in @cp-trendsplantsci.bsky.social!
www.sciencedirect.com/science/arti...
🌱Check out our new Opinion Paper with @thanvisrikant.bsky.social discussing this topic in @cp-trendsplantsci.bsky.social!
www.sciencedirect.com/science/arti...
December 12, 2025 at 11:49 AM
Can we tune a plant’s epigenetic toolkit to disrupt plant homeostasis in ways that enable phenotypic innovation?
🌱Check out our new Opinion Paper with @thanvisrikant.bsky.social discussing this topic in @cp-trendsplantsci.bsky.social!
www.sciencedirect.com/science/arti...
🌱Check out our new Opinion Paper with @thanvisrikant.bsky.social discussing this topic in @cp-trendsplantsci.bsky.social!
www.sciencedirect.com/science/arti...
Reposted by Marco Podobnik
We have a new preprint on bioRxiv from postdoc Delai Huang and colleagues. It's not about peacocks. www.biorxiv.org/content/10.6...
December 9, 2025 at 6:53 PM
We have a new preprint on bioRxiv from postdoc Delai Huang and colleagues. It's not about peacocks. www.biorxiv.org/content/10.6...
Reposted by Marco Podobnik
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Development's Pathway to Independence Programme
Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...
www.biologists.com
December 3, 2025 at 6:56 AM
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Reposted by Marco Podobnik
Exciting new #Zebrafish research from the #WeinsteinLab, led by Jong Park!
“Specialized gas-exchange endothelium of the zebrafish gill” —
www.biorxiv.org/content/10.6...
Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)
“Specialized gas-exchange endothelium of the zebrafish gill” —
www.biorxiv.org/content/10.6...
Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)
December 2, 2025 at 10:48 PM
Exciting new #Zebrafish research from the #WeinsteinLab, led by Jong Park!
“Specialized gas-exchange endothelium of the zebrafish gill” —
www.biorxiv.org/content/10.6...
Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)
“Specialized gas-exchange endothelium of the zebrafish gill” —
www.biorxiv.org/content/10.6...
Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)
Reposted by Marco Podobnik
***Super cool-project alert***⚠️ Come work with @dirkmetzler.bsky.social and me in trying to understand how transcriptional noise evolves in a phylogenetic context 🧬 Deadline 15th Dec 2025 (Project funded by @dfg.de @gevol.bsky.social)
PhD position available for theoretical and statistical modeling in my joint @gevol.bsky.social project with @luisapallares.bsky.social on the evolution of transcriptional variability and its role in adaptation and evolutionary innovation.
See
job-portal.lmu.de/jobposting/6...
See
job-portal.lmu.de/jobposting/6...
PhD candidate in biology — theoretical and statistical modeling (m/f/x)
job-portal.lmu.de
November 27, 2025 at 2:30 AM
***Super cool-project alert***⚠️ Come work with @dirkmetzler.bsky.social and me in trying to understand how transcriptional noise evolves in a phylogenetic context 🧬 Deadline 15th Dec 2025 (Project funded by @dfg.de @gevol.bsky.social)
Reposted by Marco Podobnik
Come join us in Heidelberg for the first German fish meeting 👩🔬👨🔬🧬🔬🐟🐠
November 22, 2025 at 4:03 PM
Come join us in Heidelberg for the first German fish meeting 👩🔬👨🔬🧬🔬🐟🐠
Reposted by Marco Podobnik
How does messenger RNA (mRNA) get out of the nucleus to become a protein? Eukaryotic mRNA is packaged, exported, and then translated in the cytoplasm. But how do these steps work? And what are open questions? Check out our new review for our take: www.annualreviews.org/content/jour... (1/3)
November 21, 2025 at 5:37 PM
How does messenger RNA (mRNA) get out of the nucleus to become a protein? Eukaryotic mRNA is packaged, exported, and then translated in the cytoplasm. But how do these steps work? And what are open questions? Check out our new review for our take: www.annualreviews.org/content/jour... (1/3)
Reposted by Marco Podobnik
Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 17, 2025 at 11:22 PM
Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Marco Podobnik
I am so excited to share new work on a TE insertion that regulates iridescence in swordtails, led by fantastic grad student @nadiahaghani.bsky.social and with help from many coauthors! In a time that has been so difficult to navigate, this & other projects have kept my spirits up: shorturl.at/NE65A
Insertion of an invading retrovirus regulates a novel color trait in swordtail fish
For over a century, evolutionary biologists have been motivated to understand the mechanisms through which organisms adapt to their environments. Coloration and pigmentation are remarkably variable wi...
shorturl.at
November 12, 2025 at 8:34 PM
I am so excited to share new work on a TE insertion that regulates iridescence in swordtails, led by fantastic grad student @nadiahaghani.bsky.social and with help from many coauthors! In a time that has been so difficult to navigate, this & other projects have kept my spirits up: shorturl.at/NE65A
Reposted by Marco Podobnik
🔍 In our review, led by Tina Munch, a hydrocephalus neurosurgeon, we explore this question. We examined the role of cilia in human hydrocephalus and highlight a key insight: primary cilia may play a more critical role than motile cilia, particularly through their influence on brain development.
October 30, 2025 at 8:43 PM
🔍 In our review, led by Tina Munch, a hydrocephalus neurosurgeon, we explore this question. We examined the role of cilia in human hydrocephalus and highlight a key insight: primary cilia may play a more critical role than motile cilia, particularly through their influence on brain development.
Reposted by Marco Podobnik
Good to see this study from Ribes & co in print: PAX3/PAX7 transcription factors control neural tube patterning by simultaneously repressing ventral fates via H3K27me3 deposition at silencers & activating dorsal fates as pioneer factors at enhancers
@ribes
journals.plos.org/plosbiology/...
@ribes
journals.plos.org/plosbiology/...
Dual transcriptional activities of PAX3 and PAX7 spatially encode spinal cell fates through distinct gene networks
How do transcription factors, with pleotropic functions, generate organized cellular diversity in developing tissues? This study shows that PAX3 and PAX7 orchestrate spinal cord patterning by acting a...
journals.plos.org
October 29, 2025 at 3:21 PM
Good to see this study from Ribes & co in print: PAX3/PAX7 transcription factors control neural tube patterning by simultaneously repressing ventral fates via H3K27me3 deposition at silencers & activating dorsal fates as pioneer factors at enhancers
@ribes
journals.plos.org/plosbiology/...
@ribes
journals.plos.org/plosbiology/...
Reposted by Marco Podobnik
1/2 Want to become up to date with pangenomes and genome graphs and their history? Check out this fantastic review by @zbao.bsky.social!
Complexity welcome: Pangenome graphs for comprehensive population genomics
#pangenomes #plantscience #genomegraphs
www.cambridge.org/core/journal...
Complexity welcome: Pangenome graphs for comprehensive population genomics
#pangenomes #plantscience #genomegraphs
www.cambridge.org/core/journal...
October 27, 2025 at 5:53 PM
1/2 Want to become up to date with pangenomes and genome graphs and their history? Check out this fantastic review by @zbao.bsky.social!
Complexity welcome: Pangenome graphs for comprehensive population genomics
#pangenomes #plantscience #genomegraphs
www.cambridge.org/core/journal...
Complexity welcome: Pangenome graphs for comprehensive population genomics
#pangenomes #plantscience #genomegraphs
www.cambridge.org/core/journal...
Reposted by Marco Podobnik
The Question: We know the spinal cord has 11 molecularly distinct progenitor domains generating distinct neurons, but how are these linked by actual LINEAGE relationships? When do progenitors commit to specific cardinal neuron fates, and how early is that commitment resolved?
October 26, 2025 at 5:15 PM
The Question: We know the spinal cord has 11 molecularly distinct progenitor domains generating distinct neurons, but how are these linked by actual LINEAGE relationships? When do progenitors commit to specific cardinal neuron fates, and how early is that commitment resolved?
Happy to have contributed to this big story. We present new genome assemblies, genus-wide complementation and allele-specific expression analyses in hybrids between zebrafish and closely related Danio species with divergent pigment patterns. A vertebrate model genus for basic comparative biology.
October 20, 2025 at 2:21 AM
Happy to have contributed to this big story. We present new genome assemblies, genus-wide complementation and allele-specific expression analyses in hybrids between zebrafish and closely related Danio species with divergent pigment patterns. A vertebrate model genus for basic comparative biology.
Reposted by Marco Podobnik
#ResearchCareers: Just finishing your #PhD and wondering if the DFG’s Walter Benjamin Programme is a #funding option for your next step in academia? Come and find out in our digital info talk on 14 October. No registration, the meeting link will be published here:
➡️ www.dfg.de/en/research-...
➡️ www.dfg.de/en/research-...
October 2, 2025 at 10:23 AM
#ResearchCareers: Just finishing your #PhD and wondering if the DFG’s Walter Benjamin Programme is a #funding option for your next step in academia? Come and find out in our digital info talk on 14 October. No registration, the meeting link will be published here:
➡️ www.dfg.de/en/research-...
➡️ www.dfg.de/en/research-...
Reposted by Marco Podobnik
The @crick.ac.uk is recruiting Early Career Group Leaders
- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology
Deadline 27 Nov
www.crick.ac.uk/careers-stud...
- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology
Deadline 27 Nov
www.crick.ac.uk/careers-stud...
Early career group leaders
We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.
www.crick.ac.uk
October 10, 2025 at 8:20 AM
The @crick.ac.uk is recruiting Early Career Group Leaders
- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology
Deadline 27 Nov
www.crick.ac.uk/careers-stud...
- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology
Deadline 27 Nov
www.crick.ac.uk/careers-stud...
Reposted by Marco Podobnik
Out @natcomms.nature.com:
our work on how the ❤️-supporting pericardium forms & acts in pediatric heart conditions.🎈🫀
Expanding our preprint & with our first HCR (thx to @thelovelylab.bsky.social!).
Congrats all! #devbio #zebrafish #CHD @cupediatrics.bsky.social @cudevbio.bsky.social
rdcu.be/eIJm5
our work on how the ❤️-supporting pericardium forms & acts in pediatric heart conditions.🎈🫀
Expanding our preprint & with our first HCR (thx to @thelovelylab.bsky.social!).
Congrats all! #devbio #zebrafish #CHD @cupediatrics.bsky.social @cudevbio.bsky.social
rdcu.be/eIJm5
September 30, 2025 at 5:55 PM
Out @natcomms.nature.com:
our work on how the ❤️-supporting pericardium forms & acts in pediatric heart conditions.🎈🫀
Expanding our preprint & with our first HCR (thx to @thelovelylab.bsky.social!).
Congrats all! #devbio #zebrafish #CHD @cupediatrics.bsky.social @cudevbio.bsky.social
rdcu.be/eIJm5
our work on how the ❤️-supporting pericardium forms & acts in pediatric heart conditions.🎈🫀
Expanding our preprint & with our first HCR (thx to @thelovelylab.bsky.social!).
Congrats all! #devbio #zebrafish #CHD @cupediatrics.bsky.social @cudevbio.bsky.social
rdcu.be/eIJm5
Reposted by Marco Podobnik
Do zebrafish regenerate their hearts equally? In our new paper at the @tillymommersteeg.bsky.social lab we uncovered variations in the regenerative response of 7 wt zebrafish strains leading us to identify a critical role of oxidative phosphorylation in long-term heart regeneration.
rdcu.be/eI1v5
rdcu.be/eI1v5
Oxidative phosphorylation is required for cardiomyocyte re-differentiation and long-term fish heart regeneration
Nature Cardiovascular Research - Lekkos et al. show that a metabolic switch toward oxidative phosphorylation is required for cardiomyocyte re-differentiation and heart regeneration after injury in...
rdcu.be
October 1, 2025 at 11:26 AM
Do zebrafish regenerate their hearts equally? In our new paper at the @tillymommersteeg.bsky.social lab we uncovered variations in the regenerative response of 7 wt zebrafish strains leading us to identify a critical role of oxidative phosphorylation in long-term heart regeneration.
rdcu.be/eI1v5
rdcu.be/eI1v5
Reposted by Marco Podobnik
So happy to see my first first-author paper published! 🎈
A short thread on how Ectocarpus and its TE secrets have kept me busy lately:
rdcu.be/eITQH
A short thread on how Ectocarpus and its TE secrets have kept me busy lately:
rdcu.be/eITQH
Characterization of the transposable element landscape shaping the Ectocarpus genome | Genome Biology
rdcu.be
October 1, 2025 at 8:12 AM
So happy to see my first first-author paper published! 🎈
A short thread on how Ectocarpus and its TE secrets have kept me busy lately:
rdcu.be/eITQH
A short thread on how Ectocarpus and its TE secrets have kept me busy lately:
rdcu.be/eITQH
Reposted by Marco Podobnik
Super glad to contribute to this study on chromatin evolution in brown algae! Special thanks to Jeromine Vigneau, @borglab.bsky.social and Susana Coelho for making this happen.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Rewiring of chromatin regulation underlies the evolution of brown algal multicellularity
Chromatin structure plays a central role in regulating transcription, genome stability, and epigenetic inheritance in eukaryotes. Much of our understanding of chromatin architecture and histone post-t...
www.biorxiv.org
September 19, 2025 at 7:02 PM
Super glad to contribute to this study on chromatin evolution in brown algae! Special thanks to Jeromine Vigneau, @borglab.bsky.social and Susana Coelho for making this happen.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Marco Podobnik
Many conserved exons in the heart and brain utilize weak 5 ′ splice sites, yet they are accurately spliced. But how? We show that splicing fidelity is actively enforced through a QKI-U6 checkpoint at the U1→U6 handover in essential cardiac genes during organogenesis.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
QKI ensures splicing fidelity during cardiogenesis by engaging the U6 tri-snRNP to activate splicing at weak 5ʹ splice sites
During organogenesis, precise pre-mRNA splicing is essential to assemble tissue architecture. Many developmentally essential exons bear weak 5'splice sites (5'SS) yet are spliced with high precision, ...
www.biorxiv.org
September 8, 2025 at 6:12 AM
Many conserved exons in the heart and brain utilize weak 5 ′ splice sites, yet they are accurately spliced. But how? We show that splicing fidelity is actively enforced through a QKI-U6 checkpoint at the U1→U6 handover in essential cardiac genes during organogenesis.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Marco Podobnik
We have a fully funded 3y postdoc position open!!!! Come join us @mpi-cbg.de and @poldresden.bsky.social to understand the role of Membranes in Controlling Biogenic Crystallization :) this is part of our #HFSP funded project with @noemijimenezrojo.bsky.social and @vmonje.bsky.social! Applications👇
The #MaxPlanckPostdocProgram offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. The call for applications is open now! 🚀 Take advantage of this opportunity and browse the job vacancies. www.mpg.de/en/max-planc...
September 1, 2025 at 9:17 PM
We have a fully funded 3y postdoc position open!!!! Come join us @mpi-cbg.de and @poldresden.bsky.social to understand the role of Membranes in Controlling Biogenic Crystallization :) this is part of our #HFSP funded project with @noemijimenezrojo.bsky.social and @vmonje.bsky.social! Applications👇