Misha Rosenbach, MD
@misharosenbach.bsky.social
Dermatologist (medical derm, granulomas [sarcoid & more], neutrophilic dzs [PG/Sweets/etc], inpatient derm, drug reactions [SJS/DRESS], MedEd, climate & sustainability) @pennmedicine.bsky.social Residency PD @PennDerm. Views mine, not medical advice
Reposted by Misha Rosenbach, MD
Yellow fever and dengue cases surge in South America as climate crisis fuels health issues: Disease outbreaks from South America to Europe have been worsened by rising global temperatures, experts say Surging cases of yellow fever and dengue in South America highlight the growing assault ...
Yellow fever and dengue cases surge in South America as climate crisis fuels health issues
Yellow fever and dengue cases surge in South America as climate crisis fuels health issues: Disease outbreaks from South America to Europe have been worsened by rising global temperatures, experts say Surging cases of yellow fever and dengue in South America highlight the growing assault ...
www.theguardian.com
November 14, 2025 at 12:08 PM
Yellow fever and dengue cases surge in South America as climate crisis fuels health issues: Disease outbreaks from South America to Europe have been worsened by rising global temperatures, experts say Surging cases of yellow fever and dengue in South America highlight the growing assault ...
Reposted by Misha Rosenbach, MD
#IDboardreview 25 yo M w/ recent tattoo (2 wks ago) now presents with this non-pruritic non-tender rash? Diagnosis? #medEd #IDMedEd #idsky
November 12, 2025 at 11:27 PM
#IDboardreview 25 yo M w/ recent tattoo (2 wks ago) now presents with this non-pruritic non-tender rash? Diagnosis? #medEd #IDMedEd #idsky
Reposted by Misha Rosenbach, MD
I’m delighted to share our special issue on Climate Change & Dermatology (out 1/2026)
Our intro article prefacing the issue is linked below.
Thank you #Dermatology Clinics for dedicating an issue to this important topic!
#MedSky #DermSky
www.sciencedirect.com/science/arti...
Our intro article prefacing the issue is linked below.
Thank you #Dermatology Clinics for dedicating an issue to this important topic!
#MedSky #DermSky
www.sciencedirect.com/science/arti...
Climate Change and Dermatology: A Review and Update for 2026 and Beyond
www.sciencedirect.com
November 7, 2025 at 8:52 PM
I’m delighted to share our special issue on Climate Change & Dermatology (out 1/2026)
Our intro article prefacing the issue is linked below.
Thank you #Dermatology Clinics for dedicating an issue to this important topic!
#MedSky #DermSky
www.sciencedirect.com/science/arti...
Our intro article prefacing the issue is linked below.
Thank you #Dermatology Clinics for dedicating an issue to this important topic!
#MedSky #DermSky
www.sciencedirect.com/science/arti...
Reposted by Misha Rosenbach, MD
A commentary by Richie Jeremian & Vincent Piguet, "Toward Pharmacogenomic Approaches to Hidradenitis Suppurativa" https://doi.org/10.1016/j.jid.2025.05.001 #JIDJournal #DermatologyJournal #dermatology #dermatologists #dermscience #dermatologyresearch #dermsky
November 2, 2025 at 5:05 PM
A commentary by Richie Jeremian & Vincent Piguet, "Toward Pharmacogenomic Approaches to Hidradenitis Suppurativa" https://doi.org/10.1016/j.jid.2025.05.001 #JIDJournal #DermatologyJournal #dermatology #dermatologists #dermscience #dermatologyresearch #dermsky
Reposted by Misha Rosenbach, MD
For moderate-to-severe plaque psoriasis, biologic therapies are highly effective but are available only by injection, and current oral therapies are often less effective. Research findings from the ICONIC-LEAD phase 3 trial are summarized in a Quick Take video. nej.md/47o15uv
#MedSky #DermSky
#MedSky #DermSky
November 7, 2025 at 2:20 PM
For moderate-to-severe plaque psoriasis, biologic therapies are highly effective but are available only by injection, and current oral therapies are often less effective. Research findings from the ICONIC-LEAD phase 3 trial are summarized in a Quick Take video. nej.md/47o15uv
#MedSky #DermSky
#MedSky #DermSky
Reposted by Misha Rosenbach, MD
A 52-year-old woman with hypertension presented with fatigue, vomiting, and confusion. Examination was notable for powdery, crystalline deposits on the arms, legs, trunk, and scalp. Read the full case details: nej.md/4pKf6tL
#MedSky #DermSky #Nephrology
#MedSky #DermSky #Nephrology
October 5, 2025 at 4:01 PM
A 52-year-old woman with hypertension presented with fatigue, vomiting, and confusion. Examination was notable for powdery, crystalline deposits on the arms, legs, trunk, and scalp. Read the full case details: nej.md/4pKf6tL
#MedSky #DermSky #Nephrology
#MedSky #DermSky #Nephrology
Reposted by Misha Rosenbach, MD
A 34-year-old man with recent travel to Zimbabwe presented with a 4-day history of fever and generalized weakness. A painful, crusted ulceration was noted on the parietal scalp. Read the full case details: nej.md/4nk9IL7
@meduniwien.ac.at #MedSky #IDSky #DermSky
@meduniwien.ac.at #MedSky #IDSky #DermSky
October 22, 2025 at 10:02 PM
A 34-year-old man with recent travel to Zimbabwe presented with a 4-day history of fever and generalized weakness. A painful, crusted ulceration was noted on the parietal scalp. Read the full case details: nej.md/4nk9IL7
@meduniwien.ac.at #MedSky #IDSky #DermSky
@meduniwien.ac.at #MedSky #IDSky #DermSky
I’m delighted to share our special issue on Climate Change & Dermatology (out 1/2026)
Our intro article prefacing the issue is linked below.
Thank you #Dermatology Clinics for dedicating an issue to this important topic!
#MedSky #DermSky
www.sciencedirect.com/science/arti...
Our intro article prefacing the issue is linked below.
Thank you #Dermatology Clinics for dedicating an issue to this important topic!
#MedSky #DermSky
www.sciencedirect.com/science/arti...
Climate Change and Dermatology: A Review and Update for 2026 and Beyond
www.sciencedirect.com
November 7, 2025 at 8:52 PM
I’m delighted to share our special issue on Climate Change & Dermatology (out 1/2026)
Our intro article prefacing the issue is linked below.
Thank you #Dermatology Clinics for dedicating an issue to this important topic!
#MedSky #DermSky
www.sciencedirect.com/science/arti...
Our intro article prefacing the issue is linked below.
Thank you #Dermatology Clinics for dedicating an issue to this important topic!
#MedSky #DermSky
www.sciencedirect.com/science/arti...
Reposted by Misha Rosenbach, MD
Chloe Villani at MGH on ICIs
The basics:
-113 FDA approved indications for ICIs with 12-65% response rate by tumor
-90% report iRAEs and rash is most common
-1-2% can get myocarditis with mortality about 50%
-iRAEs differ by ICI type
#ACR25
The basics:
-113 FDA approved indications for ICIs with 12-65% response rate by tumor
-90% report iRAEs and rash is most common
-1-2% can get myocarditis with mortality about 50%
-iRAEs differ by ICI type
#ACR25
October 25, 2025 at 2:53 PM
Chloe Villani at MGH on ICIs
The basics:
-113 FDA approved indications for ICIs with 12-65% response rate by tumor
-90% report iRAEs and rash is most common
-1-2% can get myocarditis with mortality about 50%
-iRAEs differ by ICI type
#ACR25
The basics:
-113 FDA approved indications for ICIs with 12-65% response rate by tumor
-90% report iRAEs and rash is most common
-1-2% can get myocarditis with mortality about 50%
-iRAEs differ by ICI type
#ACR25
Reposted by Misha Rosenbach, MD
A review of select immune checkpoints that have been identified
Immunology 101: T cells need 2 signals for full activation to migrate to the periphery
#ACR25
Immunology 101: T cells need 2 signals for full activation to migrate to the periphery
#ACR25
October 25, 2025 at 2:18 PM
A review of select immune checkpoints that have been identified
Immunology 101: T cells need 2 signals for full activation to migrate to the periphery
#ACR25
Immunology 101: T cells need 2 signals for full activation to migrate to the periphery
#ACR25
Reposted by Misha Rosenbach, MD
Previously shared: In Sweet syndrome, skin cells keep immune cells alive longer, worsening inflammation
@misharosenbach.bsky.social & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
@misharosenbach.bsky.social & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
October 25, 2025 at 1:02 PM
Previously shared: In Sweet syndrome, skin cells keep immune cells alive longer, worsening inflammation
@misharosenbach.bsky.social & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
@misharosenbach.bsky.social & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
Reposted by Misha Rosenbach, MD
SAA1/FPR2 signaling between keratinocytes & neutrophils sustains chronic inflammation in Sweet syndrome ft Jianhe Huang, Satish Sati, Olivia Ahart, Emmanuel Rapp-Reyes, Linda Zhou, Robert Micheletti, William James @misharosenbach.bsky.social & Thomas Leung (Derm) @jci.org www.jci.org/articles/vie...
October 21, 2025 at 7:50 PM
SAA1/FPR2 signaling between keratinocytes & neutrophils sustains chronic inflammation in Sweet syndrome ft Jianhe Huang, Satish Sati, Olivia Ahart, Emmanuel Rapp-Reyes, Linda Zhou, Robert Micheletti, William James @misharosenbach.bsky.social & Thomas Leung (Derm) @jci.org www.jci.org/articles/vie...
Reposted by Misha Rosenbach, MD
In Sweet syndrome, skin cells keep immune cells alive longer, worsening inflammation.
@misharosenbach.bsky.social, Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
@misharosenbach.bsky.social, Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
October 20, 2025 at 4:55 PM
In Sweet syndrome, skin cells keep immune cells alive longer, worsening inflammation.
@misharosenbach.bsky.social, Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
@misharosenbach.bsky.social, Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
Reposted by Misha Rosenbach, MD
In Sweet syndrome, skin cells keep immune cells alive longer, worsening inflammation.
ASCI member Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
ASCI member Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
October 20, 2025 at 4:40 PM
In Sweet syndrome, skin cells keep immune cells alive longer, worsening inflammation.
ASCI member Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
ASCI member Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
Thanks @jci.org for highlighting our group’s important work in #SweetSyndrome @pennmedcso.bsky.social #Derm #Dermatology @the-asci.org
In Sweet syndrome, skin cells keep immune cells alive longer, worsening inflammation.
@misharosenbach.bsky.social, Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
@misharosenbach.bsky.social, Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
October 20, 2025 at 5:36 PM
Thanks @jci.org for highlighting our group’s important work in #SweetSyndrome @pennmedcso.bsky.social #Derm #Dermatology @the-asci.org
Thanks @the-asci.org for highlighting our group’s important work in #SweetSyndrome @pennmedcso.bsky.social #Derm #Dermatology @jci.org
In Sweet syndrome, skin cells keep immune cells alive longer, worsening inflammation.
ASCI member Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
ASCI member Thomas H. Leung & team identify long-lived neutrophils that can be blocked, offering comparable efficacy to high-dose corticosteroids in coculture assays: www.jci.org/articles/vie...
October 20, 2025 at 5:35 PM
Thanks @the-asci.org for highlighting our group’s important work in #SweetSyndrome @pennmedcso.bsky.social #Derm #Dermatology @jci.org
Reposted by Misha Rosenbach, MD
Large study of COVID outcomes with US Veterans with updated mRNA vaccines
www.nejm.org/doi/full/10....
1/2
www.nejm.org/doi/full/10....
1/2
Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans | NEJM
Amid the declining clinical severity of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection and diminishing public uptake of annual coronavirus disease
2019 (Covid-19) vaccines, ...
www.nejm.org
October 14, 2025 at 4:26 PM
Large study of COVID outcomes with US Veterans with updated mRNA vaccines
www.nejm.org/doi/full/10....
1/2
www.nejm.org/doi/full/10....
1/2
Reposted by Misha Rosenbach, MD
Inhaler-related #greenhouse gas emissions in the VA health system dropped 68% from 2008 to 2023, primarily due to policy and formulary changes favoring lower-emission inhaler options.
ja.ma/4nYMM54
ja.ma/4nYMM54
October 6, 2025 at 4:30 PM
Inhaler-related #greenhouse gas emissions in the VA health system dropped 68% from 2008 to 2023, primarily due to policy and formulary changes favoring lower-emission inhaler options.
ja.ma/4nYMM54
ja.ma/4nYMM54
Reposted by Misha Rosenbach, MD
The world produces enough food, yet billions lack access to healthy & sustainable diets. A new EAT–Lancet report presents a science-based approach to improve health, safeguard our environment & provide for a projected 9.6 billion people by 2050.
🔗 bit.ly/3W7rxlP
🔗 bit.ly/3W7rxlP
October 3, 2025 at 7:29 AM
The world produces enough food, yet billions lack access to healthy & sustainable diets. A new EAT–Lancet report presents a science-based approach to improve health, safeguard our environment & provide for a projected 9.6 billion people by 2050.
🔗 bit.ly/3W7rxlP
🔗 bit.ly/3W7rxlP
Reposted by Misha Rosenbach, MD
A 42-year-old man presented with an expanding, asymptomatic rash on his trunk. Examination showed multiple papulosquamous plaques on the torso and a larger patch with central clearing and peripheral scaling on the left side. Read the full case details: nej.md/4m9mawS
#MedSky #DermSky
#MedSky #DermSky
September 15, 2025 at 4:04 PM
A 42-year-old man presented with an expanding, asymptomatic rash on his trunk. Examination showed multiple papulosquamous plaques on the torso and a larger patch with central clearing and peripheral scaling on the left side. Read the full case details: nej.md/4m9mawS
#MedSky #DermSky
#MedSky #DermSky
Reposted by Misha Rosenbach, MD
What treatments work for dermatologic immune-related adverse events (D-irAEs)? www.jidinnovations.org/article/S266... #medderm #dermsky
Assessing Treatment Efficacy for Dermatologic Immune-related Adverse Events: A Systematic Review
The management of dermatologic immune-related adverse events (D-irAEs) remains inconsistent
due to variability in treatment responses and a lack of standardized guidelines. Establishing
evidence-based...
www.jidinnovations.org
September 16, 2025 at 12:25 PM
What treatments work for dermatologic immune-related adverse events (D-irAEs)? www.jidinnovations.org/article/S266... #medderm #dermsky
Reposted by Misha Rosenbach, MD
The latest issue of the JID is now live.
Dive into the October issue at www.jidonline.org/current
#DermatologyJournal #dermatology #dermsky #dermatologists #dermresearch #dermscience #dermatologyresearch
Dive into the October issue at www.jidonline.org/current
#DermatologyJournal #dermatology #dermsky #dermatologists #dermresearch #dermscience #dermatologyresearch
September 19, 2025 at 4:00 PM
The latest issue of the JID is now live.
Dive into the October issue at www.jidonline.org/current
#DermatologyJournal #dermatology #dermsky #dermatologists #dermresearch #dermscience #dermatologyresearch
Dive into the October issue at www.jidonline.org/current
#DermatologyJournal #dermatology #dermsky #dermatologists #dermresearch #dermscience #dermatologyresearch
Reposted by Misha Rosenbach, MD
A 71-year-old man presented with a 2-year history of a darkening line on his left thumbnail. Also noted were a brown discoloration of the left thumbnail and hyperpigmentation of the proximal nail fold and tip of the thumb. Read the full case details: nej.md/4ngdaHb
#MedSky #DermSky
#MedSky #DermSky
September 8, 2025 at 4:01 PM
A 71-year-old man presented with a 2-year history of a darkening line on his left thumbnail. Also noted were a brown discoloration of the left thumbnail and hyperpigmentation of the proximal nail fold and tip of the thumb. Read the full case details: nej.md/4ngdaHb
#MedSky #DermSky
#MedSky #DermSky
Reposted by Misha Rosenbach, MD
A 44-year-old man presented with a 4-day history of an itchy rash and a 2-day history of fever and malaise. The rash had first appeared on the scalp and then spread across the body within 24 hours. What is the most likely diagnosis? nej.md/IC09112025
#MedSky #DermSky
#MedSky #DermSky
September 12, 2025 at 7:09 PM
A 44-year-old man presented with a 4-day history of an itchy rash and a 2-day history of fever and malaise. The rash had first appeared on the scalp and then spread across the body within 24 hours. What is the most likely diagnosis? nej.md/IC09112025
#MedSky #DermSky
#MedSky #DermSky
South Korea has long been a mecca for skincare enthusiasts, and part of Rejuran’s success is due to a broader interest in Korea-born beauty products and rituals. But some American doctors remain skeptical.
🔗 on.wsj.com/41Fp6dd
🔗 on.wsj.com/41Fp6dd
September 5, 2025 at 11:04 PM