Adam Hendricks
@mindonmotors.bsky.social
kinesins, dynein, microtubules, neurodegeneration
Help me spread the word about an opening for the Furino Chair in Bioengineering in the Department of Bioengineering at McGill University. We seek candidates focused on developing biotherapeutic approaches to cancer, including but not limited to mRNA vaccines, CAR-T, and immunotherapy. (1/3)
November 12, 2025 at 6:05 PM
Help me spread the word about an opening for the Furino Chair in Bioengineering in the Department of Bioengineering at McGill University. We seek candidates focused on developing biotherapeutic approaches to cancer, including but not limited to mRNA vaccines, CAR-T, and immunotherapy. (1/3)
A few highlights from our new preprint:
On taxol-stabilized microtubules In vitro, wild-type (WT) and phosphor-resistive (AP) tau form well-defined envelopes, while phosphomimetic (E14) tau does not bind cooperatively.
On taxol-stabilized microtubules In vitro, wild-type (WT) and phosphor-resistive (AP) tau form well-defined envelopes, while phosphomimetic (E14) tau does not bind cooperatively.
August 4, 2025 at 5:43 PM
A few highlights from our new preprint:
On taxol-stabilized microtubules In vitro, wild-type (WT) and phosphor-resistive (AP) tau form well-defined envelopes, while phosphomimetic (E14) tau does not bind cooperatively.
On taxol-stabilized microtubules In vitro, wild-type (WT) and phosphor-resistive (AP) tau form well-defined envelopes, while phosphomimetic (E14) tau does not bind cooperatively.
Very happy to share our latest work on tau. We show that tau binds cooperatively in living neurons. Phosphorylation disrupts tau envelopes, and misregulates axonal transport.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons
Tau, a neuronal microtubule-associated protein (MAP), organizes the axonal cytoskeleton and regulates intracellular transport. Tau hyperphosphorylation is closely linked to neurodegeneration in tauopa...
www.biorxiv.org
August 1, 2025 at 12:24 PM
Very happy to share our latest work on tau. We show that tau binds cooperatively in living neurons. Phosphorylation disrupts tau envelopes, and misregulates axonal transport.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Adam Hendricks
Steven M. Block | 2025 Benjamin Franklin Medal in Life Science
fi.edu/en/awards/la...
youtu.be/yeZJXeQo3JQ?... via @YouTube
fi.edu/en/awards/la...
youtu.be/yeZJXeQo3JQ?... via @YouTube
Steven M. Block
fi.edu
May 7, 2025 at 9:10 AM
Steven M. Block | 2025 Benjamin Franklin Medal in Life Science
fi.edu/en/awards/la...
youtu.be/yeZJXeQo3JQ?... via @YouTube
fi.edu/en/awards/la...
youtu.be/yeZJXeQo3JQ?... via @YouTube
Reposted by Adam Hendricks
Great chance for Canadian researchers to attend a great scientific meeting in Canada!
Missed the deadline for the abstract submission for the CSMB meeting on Protein Homeostasis – From Basic Science to Human Health?
Well the deadline was extended until April 15th!
event.fourwaves.com/csmb-prince-...
Well the deadline was extended until April 15th!
event.fourwaves.com/csmb-prince-...
2025 CSMB-PRinCE Joint Conference
Fourwaves - 2025 CSMB-PRinCE Joint Conference
event.fourwaves.com
April 1, 2025 at 3:48 PM
Great chance for Canadian researchers to attend a great scientific meeting in Canada!
Reposted by Adam Hendricks
Competition for microtubule lattice spacing between a microtubule expander and compactor. https://www.biorxiv.org/content/10.1101/2025.02.28.640185v1
March 3, 2025 at 11:30 PM
Competition for microtubule lattice spacing between a microtubule expander and compactor. https://www.biorxiv.org/content/10.1101/2025.02.28.640185v1