DMartin
@drddom.bsky.social
Assistant Prof at UWaterloo in Biology. Study autophagy & protein lipidation (S-acylation & N-myristoylation) in ALS & Huntington disease. Expect science, food, some cdnpoli, & dog pics
https://neurdyphagylab.squarespace.com/
https://neurdyphagylab.squarespace.com/
There's a reason Julia Child was an icon & this cookbook is timeless. First time making coq au vin. Not sure there's a good way to photograph it. Only took 3 hours, but damn that was amazing. Paired it with spatzle. Worth the time.
November 9, 2025 at 2:47 AM
There's a reason Julia Child was an icon & this cookbook is timeless. First time making coq au vin. Not sure there's a good way to photograph it. Only took 3 hours, but damn that was amazing. Paired it with spatzle. Worth the time.
Welcome to the Canadian Hunger Games where the motto truly is 'May the odds be ever in your favour!'
Canada makes pitch for US researchers to relocate with $1.7bn in new funding. My story for @science.org 🧪
www.science.org/content/arti...
www.science.org/content/arti...
Canada’s new budget aims to lure U.S. researchers to relocate
Spending plan also calls for smaller research spending cut than feared
www.science.org
November 6, 2025 at 1:55 AM
Welcome to the Canadian Hunger Games where the motto truly is 'May the odds be ever in your favour!'
Reposted by DMartin
“Canada is the best place to live, and top talent from around the world want to come here because they see opportunities and possibilities to contribute to cutting-edge research”...
...he says while allocating $1.7B to bribe people to move here and cutting grant funding. Unbelievable.
...he says while allocating $1.7B to bribe people to move here and cutting grant funding. Unbelievable.
Canada makes pitch for US researchers to relocate with $1.7bn in new funding. My story for @science.org 🧪
www.science.org/content/arti...
www.science.org/content/arti...
Canada’s new budget aims to lure U.S. researchers to relocate
Spending plan also calls for smaller research spending cut than feared
www.science.org
November 5, 2025 at 10:16 PM
“Canada is the best place to live, and top talent from around the world want to come here because they see opportunities and possibilities to contribute to cutting-edge research”...
...he says while allocating $1.7B to bribe people to move here and cutting grant funding. Unbelievable.
...he says while allocating $1.7B to bribe people to move here and cutting grant funding. Unbelievable.
Dear CIHR Reviewers, pls keep in mind that knowledge users on grants see the reviews. If you tell us a protein/gene is not interesting/less important because it's rare, it reads as those patients aren't important.
November 5, 2025 at 11:32 PM
Dear CIHR Reviewers, pls keep in mind that knowledge users on grants see the reviews. If you tell us a protein/gene is not interesting/less important because it's rare, it reads as those patients aren't important.
Scientists, please come to Canada! We'll pay to bring you here, but you need to fund your own research!
Came here to see if I was interpreting this correctly. Seems like I am.
November 4, 2025 at 9:39 PM
Scientists, please come to Canada! We'll pay to bring you here, but you need to fund your own research!
Reposted by DMartin
The Canadian government has seemingly never read a single one of its own commissioned reports on what Canadian science needs. (It's not more people.)
Globe & Mail reports “the budget is expected to include up to $1-billion to attract high-quality talent and researchers from the United States and elsewhere”
So far hospitals and universities have been going it alone….
www.ctvnews.ca/health/artic...
@ctvnews-mirror.bsky.social
So far hospitals and universities have been going it alone….
www.ctvnews.ca/health/artic...
@ctvnews-mirror.bsky.social
November 4, 2025 at 9:28 PM
The Canadian government has seemingly never read a single one of its own commissioned reports on what Canadian science needs. (It's not more people.)
What a week! Submitted my NSERC today. Submitted a paper today. Incoming PhD got a scholarship today! And PDF landed an award/small grant! Can't wait to tell you all the details when we can.
Now I need to rest before a double header talks tomorrow at the HSC meeting!
Now I need to rest before a double header talks tomorrow at the HSC meeting!
November 1, 2025 at 1:31 AM
What a week! Submitted my NSERC today. Submitted a paper today. Incoming PhD got a scholarship today! And PDF landed an award/small grant! Can't wait to tell you all the details when we can.
Now I need to rest before a double header talks tomorrow at the HSC meeting!
Now I need to rest before a double header talks tomorrow at the HSC meeting!
Been awhile since I've been so nervous & excited to work in the lab. Today I'm helping culture human stem cells into muscle & motor neurons. The cells need to be fed daily & I'm helping while a student is away. Contamination is a constant fear. Thank you @stemcell.com for the help!
October 17, 2025 at 8:00 PM
Been awhile since I've been so nervous & excited to work in the lab. Today I'm helping culture human stem cells into muscle & motor neurons. The cells need to be fed daily & I'm helping while a student is away. Contamination is a constant fear. Thank you @stemcell.com for the help!
Reposted by DMartin
During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost!
apply.interfolio.com/174756
apply.interfolio.com/174756
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 14, 2025 at 5:35 PM
During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost!
apply.interfolio.com/174756
apply.interfolio.com/174756
Reposted by DMartin
We used live-cell imaging with plus-end binding protein EB3 to determine microtubule polarity in astrocytes for the first time. They are ~88% plus-ends out.
3/x
3/x
October 13, 2025 at 8:44 PM
We used live-cell imaging with plus-end binding protein EB3 to determine microtubule polarity in astrocytes for the first time. They are ~88% plus-ends out.
3/x
3/x
Reposted by DMartin
Excited to share our preprint on cytoskeletal organization in astrocytes!
biorxiv.org/content/10.110…
Postdoc @mewynne759 looked at microtubules, IFs/GFAP & actin along long elaborate processes.
Wonderful to collaborate w postdoc @dharshinigopal & @NogalesLab on cryo-ET 🤓
1/x
biorxiv.org/content/10.110…
Postdoc @mewynne759 looked at microtubules, IFs/GFAP & actin along long elaborate processes.
Wonderful to collaborate w postdoc @dharshinigopal & @NogalesLab on cryo-ET 🤓
1/x
https://biorxiv.org/content/10.110…
October 13, 2025 at 8:44 PM
Excited to share our preprint on cytoskeletal organization in astrocytes!
biorxiv.org/content/10.110…
Postdoc @mewynne759 looked at microtubules, IFs/GFAP & actin along long elaborate processes.
Wonderful to collaborate w postdoc @dharshinigopal & @NogalesLab on cryo-ET 🤓
1/x
biorxiv.org/content/10.110…
Postdoc @mewynne759 looked at microtubules, IFs/GFAP & actin along long elaborate processes.
Wonderful to collaborate w postdoc @dharshinigopal & @NogalesLab on cryo-ET 🤓
1/x
Amazing news today for HD patients! I hope this keeps up.
uniQure reports promising results from a key clinical study, showing that its experimental gene therapy, AMT-130, may slow the progress of Huntington's disease
en.hdbuzz.net/the-first-do...
en.hdbuzz.net/the-first-do...
September 24, 2025 at 7:56 PM
Amazing news today for HD patients! I hope this keeps up.
Working on my NSERC renewal & being reminded about all the projects we had lined up that have been scooped. At $37k/yr there's only so much we can do. And it's not much. Canadian science is laughably underfunded.
September 24, 2025 at 12:46 AM
Working on my NSERC renewal & being reminded about all the projects we had lined up that have been scooped. At $37k/yr there's only so much we can do. And it's not much. Canadian science is laughably underfunded.
Reposted by DMartin
A big study in JAMA last year in which 185 909 children were exposed to acetaminophen during pregnancy. Conclusion: Acetaminophen use during pregnancy was not associated with children's risk of autism, ADHD, or intellectual disability in sibling control analysis.
pubmed.ncbi.nlm.nih.gov/38592388/
pubmed.ncbi.nlm.nih.gov/38592388/
Acetaminophen Use During Pregnancy and Children's Risk of Autism, ADHD, and Intellectual Disability - PubMed
Acetaminophen use during pregnancy was not associated with children's risk of autism, ADHD, or intellectual disability in sibling control analysis. This suggests that associations observed in other mo...
pubmed.ncbi.nlm.nih.gov
September 22, 2025 at 6:05 PM
A big study in JAMA last year in which 185 909 children were exposed to acetaminophen during pregnancy. Conclusion: Acetaminophen use during pregnancy was not associated with children's risk of autism, ADHD, or intellectual disability in sibling control analysis.
pubmed.ncbi.nlm.nih.gov/38592388/
pubmed.ncbi.nlm.nih.gov/38592388/
Reposted by DMartin
SKY-0515, an oral drug, safely lowers huntingtin in people with HD—and may also reduce PMS1, a DNA repair protein. This two-pronged approach could open new doors for HD treatment. A larger Phase 2/3 trial is now underway.
Full article: en.hdbuzz.net/sky-0515-low...
Full article: en.hdbuzz.net/sky-0515-low...
SKY-0515 Lowers Huntingtin In People With Huntington’s Disease In Trial Update – HDBuzz
en.hdbuzz.net
September 19, 2025 at 3:16 PM
SKY-0515, an oral drug, safely lowers huntingtin in people with HD—and may also reduce PMS1, a DNA repair protein. This two-pronged approach could open new doors for HD treatment. A larger Phase 2/3 trial is now underway.
Full article: en.hdbuzz.net/sky-0515-low...
Full article: en.hdbuzz.net/sky-0515-low...
Reposted by DMartin
David Letterman on his career mocking presidents: “Beating up on these people, rightly or wrongly, accurately or perhaps inaccurately, in the name of comedy—not once were we squeezed by anyone from any governmental agency, let alone the dreaded FCC.”
Watch more: bit.ly/4n0Uv2p
Watch more: bit.ly/4n0Uv2p
September 18, 2025 at 7:31 PM
David Letterman on his career mocking presidents: “Beating up on these people, rightly or wrongly, accurately or perhaps inaccurately, in the name of comedy—not once were we squeezed by anyone from any governmental agency, let alone the dreaded FCC.”
Watch more: bit.ly/4n0Uv2p
Watch more: bit.ly/4n0Uv2p
So, maybe this is a good time for Canadian networks to rescue shows like @jimmykimmel.com & The Late Show?
September 18, 2025 at 2:18 PM
So, maybe this is a good time for Canadian networks to rescue shows like @jimmykimmel.com & The Late Show?
The very talented @cailyncreative.bsky.social took inspiration from Ruby at the vet & created this masterpiece on our whiteboard in the lab. Pretty sure we can never use it again & I'm ok with that. Makes me smile every time I see it.
Thanks again Cailyn!
Thanks again Cailyn!
September 16, 2025 at 3:19 AM
The very talented @cailyncreative.bsky.social took inspiration from Ruby at the vet & created this masterpiece on our whiteboard in the lab. Pretty sure we can never use it again & I'm ok with that. Makes me smile every time I see it.
Thanks again Cailyn!
Thanks again Cailyn!
Reposted by DMartin
Sometimes I think everything is going to be ok, and we’ll be able to secure grants to keep doing this cool stuff we’re doing.
Sometimes I don’t really know.
Sigh.
Tomorrow will be better.
Sometimes I don’t really know.
Sigh.
Tomorrow will be better.
September 16, 2025 at 3:13 AM
Sometimes I think everything is going to be ok, and we’ll be able to secure grants to keep doing this cool stuff we’re doing.
Sometimes I don’t really know.
Sigh.
Tomorrow will be better.
Sometimes I don’t really know.
Sigh.
Tomorrow will be better.
Feels like the world is on fire lately. So enjoy this pic of Ruby at the vet's office just after getting her vaccines. She loves the vet. Feel like she'd make a great receptionist.
September 12, 2025 at 9:43 PM
Feels like the world is on fire lately. So enjoy this pic of Ruby at the vet's office just after getting her vaccines. She loves the vet. Feel like she'd make a great receptionist.
Reposted by DMartin
Pridopidine has been studied for decades as a possible treatment for Huntington’s disease. The PROOF-HD trial didn’t meet its primary goals, but its full results are now published—making valuable data available for the HD community.
en.hdbuzz.net/proof-in-the...
en.hdbuzz.net/proof-in-the...
September 10, 2025 at 4:39 PM
Pridopidine has been studied for decades as a possible treatment for Huntington’s disease. The PROOF-HD trial didn’t meet its primary goals, but its full results are now published—making valuable data available for the HD community.
en.hdbuzz.net/proof-in-the...
en.hdbuzz.net/proof-in-the...
Save the Date for the next @csmb-scbm.bsky.social meeting:
Membrane Proteins in Health & Diseases
April 8-12, 2026 in beautiful Banff!
Looks like there's something for everyone.
event.fourwaves.com/2026csmb/pages
Membrane Proteins in Health & Diseases
April 8-12, 2026 in beautiful Banff!
Looks like there's something for everyone.
event.fourwaves.com/2026csmb/pages
September 11, 2025 at 7:23 PM
Save the Date for the next @csmb-scbm.bsky.social meeting:
Membrane Proteins in Health & Diseases
April 8-12, 2026 in beautiful Banff!
Looks like there's something for everyone.
event.fourwaves.com/2026csmb/pages
Membrane Proteins in Health & Diseases
April 8-12, 2026 in beautiful Banff!
Looks like there's something for everyone.
event.fourwaves.com/2026csmb/pages
I have reached the stage of file saving where the grant is labled as final, final-maybe, final maybe maybe... pray for me.
September 8, 2025 at 9:05 PM
I have reached the stage of file saving where the grant is labled as final, final-maybe, final maybe maybe... pray for me.
Reposted by DMartin
Come join us at University of Toronto. We're hiring a Professor of computational cognitive neuroscience.
#neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...
#neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...
Professor - Computational Cognitive Neuroscience
Professor - Computational Cognitive Neuroscience
jobs.utoronto.ca
September 5, 2025 at 8:22 AM
Come join us at University of Toronto. We're hiring a Professor of computational cognitive neuroscience.
#neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...
#neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...
Reposted by DMartin
For anyone on the neuroscience job market, our ads are up. We are looking for anyone working in systems neuroscience of animals to join us in southern Alberta 🇨🇦
#academicsky #neuroskyence #neuroethology #academicjobs #Canada
neurojobs.sfn.org/job/39049/as...
#academicsky #neuroskyence #neuroethology #academicjobs #Canada
neurojobs.sfn.org/job/39049/as...
Assistant Professor (Neuroscience, Tenure Track) - Lethbridge (City), Alberta (CA) job with University of Lethbridge | 39049
Assistant Professor (tenure track) of the Department of Neuroscience at the University of Lethbridge, Alberta, Canada
neurojobs.sfn.org
September 4, 2025 at 7:59 PM
For anyone on the neuroscience job market, our ads are up. We are looking for anyone working in systems neuroscience of animals to join us in southern Alberta 🇨🇦
#academicsky #neuroskyence #neuroethology #academicjobs #Canada
neurojobs.sfn.org/job/39049/as...
#academicsky #neuroskyence #neuroethology #academicjobs #Canada
neurojobs.sfn.org/job/39049/as...