Krishna Melnattur
@melnattur.bsky.social
Asst Prof at Ashoka Univ | ex: Staff Scientist at WUSTL neuroscience | sleep scientist | lover of things that love dew
melnatturlab.weebly.com
melnatturlab.weebly.com
Pinned
Krishna Melnattur
@melnattur.bsky.social
· Dec 13
Neuroscience of Sleep
Sleep science is at an exciting juncture. The realization that sleep is near universal among animals has revolutionized the field. The ubiquity of sleep extends to the discovery of different sleep st…
meetings.embo.org
We are super excited for this conference on the Neuroscience of Sleep, 11-13 March 2025, at the India Habitat Centre, New Delhi. The program is terrific and the venue lovely, do apply! Re-skeets appreciated! meetings.embo.org/event/25-neu...
Reposted by Krishna Melnattur
@senapati.bsky.social latest and greatest! Charly Treiber on board too. Over and out.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Visceral signaling of post-ingestive malaise directs memory updating in Drosophila
Consolidation is a time when labile memories transition to a stable form. Malaise learning in Drosophila reveals consolidation to also permit memory updating. Flies taught to associate one of two odor...
www.biorxiv.org
October 23, 2025 at 8:32 PM
@senapati.bsky.social latest and greatest! Charly Treiber on board too. Over and out.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Krishna Melnattur
"Universities have existed for more than a thousand years — and for almost all of that time, they weren’t centers of research. What changed in 19th century Germany?" asteriskmag.substack.com/p/the-origin...
The Origin of the Research University
Universities have existed for more than a thousand years — and for almost all of that time, they weren’t centers of research. What changed in 19th century Germany?
asteriskmag.substack.com
October 21, 2025 at 11:09 PM
"Universities have existed for more than a thousand years — and for almost all of that time, they weren’t centers of research. What changed in 19th century Germany?" asteriskmag.substack.com/p/the-origin...
Happy to share our lab’s first preprint! ‘Mutations in antimicrobial peptides differently affect sleep and plasticity’. Led by @rahulkumar211.bsky.social, with help from many in the lab. In collaboration with @evoimmunoimroze A thread 1/n www.biorxiv.org/content/10.1...
Mutations in antimicrobial peptides differently affect sleep and plasticity
Molecules implicated in host defense can, independent of their roles as immune mediators, regulate sleep. In mammals, cytokines such as Tumor Necrosis Factor α (TNF α) and Interleukin 1β (IL1 β) promo...
www.biorxiv.org
October 1, 2025 at 8:28 PM
Happy to share our lab’s first preprint! ‘Mutations in antimicrobial peptides differently affect sleep and plasticity’. Led by @rahulkumar211.bsky.social, with help from many in the lab. In collaboration with @evoimmunoimroze A thread 1/n www.biorxiv.org/content/10.1...
Reposted by Krishna Melnattur
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Krishna Melnattur
Fresh results now in bioRxiv! 🎉 We know about the function of NREM sleep for overnight memory consolidation. But what about REM sleep? We found that in aging, slow delta waves can intrude phasic REM periods, and this, is associated with worse overnight consolidation 🧠 (1/5) doi.org/10.1101/2025...
REM Sleep Misfires: Intruding Delta Waves Forecast Tau, Amyloid, and Forgetting in Aging
Rapid Eye Movement (REM) sleep degrades with age, and more severely in Alzheimer's disease (AD). REM sleep comprises about twenty percent of adult sleep, alternates between phasic and tonic periods, a...
doi.org
August 23, 2025 at 2:32 PM
Fresh results now in bioRxiv! 🎉 We know about the function of NREM sleep for overnight memory consolidation. But what about REM sleep? We found that in aging, slow delta waves can intrude phasic REM periods, and this, is associated with worse overnight consolidation 🧠 (1/5) doi.org/10.1101/2025...
Reposted by Krishna Melnattur
We are still accepting applications for the #postdoc opportunity in the lab 🕵♀️ 🧠
More details 👇
Postdoctoral position: lnkd.in/g4TkRxpM
Research directions: lnkd.in/eV2iMKGf
Our team and philosophy: lnkd.in/eh3nnNgq
⏬
More details 👇
Postdoctoral position: lnkd.in/g4TkRxpM
Research directions: lnkd.in/eV2iMKGf
Our team and philosophy: lnkd.in/eh3nnNgq
⏬
August 25, 2025 at 4:32 AM
We are still accepting applications for the #postdoc opportunity in the lab 🕵♀️ 🧠
More details 👇
Postdoctoral position: lnkd.in/g4TkRxpM
Research directions: lnkd.in/eV2iMKGf
Our team and philosophy: lnkd.in/eh3nnNgq
⏬
More details 👇
Postdoctoral position: lnkd.in/g4TkRxpM
Research directions: lnkd.in/eV2iMKGf
Our team and philosophy: lnkd.in/eh3nnNgq
⏬
Reposted by Krishna Melnattur
"The aim of science is not to open the door to infinite wisdom but to set a limit to infinite error.”
- Bertolt Brecht
The Life of Galileo
- Bertolt Brecht
The Life of Galileo
August 18, 2025 at 6:06 PM
"The aim of science is not to open the door to infinite wisdom but to set a limit to infinite error.”
- Bertolt Brecht
The Life of Galileo
- Bertolt Brecht
The Life of Galileo
Reposted by Krishna Melnattur
More new science from the lab! Led by @nathancsharris.bsky.social (now at GA State) and PD Priya Dutta.
We describe how experience tunes the ratios of functional receptors in a single sensory neuron via coordinating transcriptional and post-transcriptional mechanisms to drive response plasticity.
We describe how experience tunes the ratios of functional receptors in a single sensory neuron via coordinating transcriptional and post-transcriptional mechanisms to drive response plasticity.
Experience-dependent reconfiguration of receptors at a sensory compartment regulates neuronal plasticity https://www.biorxiv.org/content/10.1101/2025.08.13.670147v1
August 15, 2025 at 12:58 AM
More new science from the lab! Led by @nathancsharris.bsky.social (now at GA State) and PD Priya Dutta.
We describe how experience tunes the ratios of functional receptors in a single sensory neuron via coordinating transcriptional and post-transcriptional mechanisms to drive response plasticity.
We describe how experience tunes the ratios of functional receptors in a single sensory neuron via coordinating transcriptional and post-transcriptional mechanisms to drive response plasticity.
Happy to share a wonderful Meeting Review of our @sleepneuroscience.bsky.social
meeting in March! #EMBONeuroSleep
shorturl.at/bFxPl
meeting in March! #EMBONeuroSleep
shorturl.at/bFxPl
Reflections on the EMBO Workshop: Neuroscience of Sleep 2025
Summary: The inaugural EMBO workshop on the neuroscience of sleep brought together a global sleep research community to discuss recent advances across species, scales and systems. The meeting explored...
shorturl.at
July 30, 2025 at 8:45 AM
Happy to share a wonderful Meeting Review of our @sleepneuroscience.bsky.social
meeting in March! #EMBONeuroSleep
shorturl.at/bFxPl
meeting in March! #EMBONeuroSleep
shorturl.at/bFxPl
Reposted by Krishna Melnattur
Sleep disturbance as the strongest predictor of subsequent psychiatric disorders in young people (greater than family history and adverse childhood experiences). Sleep disturbance is modifiable, a key node for intervention.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Prediction of mental health risk in adolescents - Nature Medicine
Using longitudinal survey and neuroimaging data from more than 11,000 adolescents in the United States, a machine learning model shows promising performance in identifying individuals at greater risk ...
www.nature.com
June 15, 2025 at 2:33 PM
Sleep disturbance as the strongest predictor of subsequent psychiatric disorders in young people (greater than family history and adverse childhood experiences). Sleep disturbance is modifiable, a key node for intervention.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Agree 100%. A lot of students think of science as a hit parade, and don’t like sweating the small stuff. But the small stuff matters
To do or say anything at all meaningful in something, you need to have the ability to focus on the small, boring, annoyingly finicky, unsexy parts of it.
Crackpots *never* do. They never, once, concern themselves with those unsexy boring things.
Crackpots *never* do. They never, once, concern themselves with those unsexy boring things.
May 29, 2025 at 9:07 AM
Agree 100%. A lot of students think of science as a hit parade, and don’t like sweating the small stuff. But the small stuff matters
Interesting read from the Seelig lab
Dynamics of glia and neurons regulate homeostatic rest, sleep and feeding behavior in Drosophila - Nature Neuroscience
Animals alternate between active periods and periods of rest or sleep. This study in fruit flies points to brain metabolism as a cause for this and shows that a network of glial cells interacting with...
www.nature.com
April 21, 2025 at 4:11 PM
Interesting read from the Seelig lab
And, it's a wrap! 3 wonderful days after a year in planning for the EMBO Workshop Neuroscience of Sleep @sleepneuroscience.bsky.social .
March 17, 2025 at 8:37 PM
And, it's a wrap! 3 wonderful days after a year in planning for the EMBO Workshop Neuroscience of Sleep @sleepneuroscience.bsky.social .
Reposted by Krishna Melnattur
Amazing time indeed. Thank you so much, everybody, and @melnattur.bsky.social particularly! 🐙
Had a really amazing time @sleepneuroscience.bsky.social at Neuroscience of sleep conference in Delhi. Thought provoking science and fabulous company. Thankyou @melnattur.bsky.social and other organisers.
March 16, 2025 at 7:34 AM
Amazing time indeed. Thank you so much, everybody, and @melnattur.bsky.social particularly! 🐙
Reposted by Krishna Melnattur
Had a really amazing time @sleepneuroscience.bsky.social at Neuroscience of sleep conference in Delhi. Thought provoking science and fabulous company. Thankyou @melnattur.bsky.social and other organisers.
March 14, 2025 at 4:04 PM
Had a really amazing time @sleepneuroscience.bsky.social at Neuroscience of sleep conference in Delhi. Thought provoking science and fabulous company. Thankyou @melnattur.bsky.social and other organisers.
Reposted by Krishna Melnattur
🎉🛍️ Exciting news!
The EMBO workshop- Neuroscience of Sleep 2025 kit is here. It includes a T-shirt, tote bag, notebook, and pencil. We hope all the attendees are ready to dive into the latest in sleep research 🧠💤.
Get ready to learn, connect, and take notes in style! ✨
#EMBOneuroSleep
The EMBO workshop- Neuroscience of Sleep 2025 kit is here. It includes a T-shirt, tote bag, notebook, and pencil. We hope all the attendees are ready to dive into the latest in sleep research 🧠💤.
Get ready to learn, connect, and take notes in style! ✨
#EMBOneuroSleep
March 9, 2025 at 8:35 AM
🎉🛍️ Exciting news!
The EMBO workshop- Neuroscience of Sleep 2025 kit is here. It includes a T-shirt, tote bag, notebook, and pencil. We hope all the attendees are ready to dive into the latest in sleep research 🧠💤.
Get ready to learn, connect, and take notes in style! ✨
#EMBOneuroSleep
The EMBO workshop- Neuroscience of Sleep 2025 kit is here. It includes a T-shirt, tote bag, notebook, and pencil. We hope all the attendees are ready to dive into the latest in sleep research 🧠💤.
Get ready to learn, connect, and take notes in style! ✨
#EMBOneuroSleep
Reposted by Krishna Melnattur
I am thrilled that our paper, which is packed with our 10 years of data on the venom proteins of the parasitoid wasp Asobara japonica, has just been published!
Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism | Science Advances www.science.org/doi/10.1126/...
Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism | Science Advances www.science.org/doi/10.1126/...
Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism
Two parasitoid wasp venom proteins induce imaginal disc degradation of its host fly Drosophila larva, ensuring parasitism success.
www.science.org
January 29, 2025 at 8:30 PM
I am thrilled that our paper, which is packed with our 10 years of data on the venom proteins of the parasitoid wasp Asobara japonica, has just been published!
Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism | Science Advances www.science.org/doi/10.1126/...
Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism | Science Advances www.science.org/doi/10.1126/...
Thanks to everyone who applied. Applications are now closed. Please follow the account quoted here for updates!
#EMBOconferenceAlert!
EMBO Workshop- Neuroscience of Sleep
📆 11 – 13 March 2025
📍 India Habitat Centre, Lodhi Road, New Delhi
🌐 meetings.embo.org/event/25-neu...
⏳ Registration Deadline: 19 January 2025
#EMBOworkshop #Neuroscienceofsleep
EMBO Workshop- Neuroscience of Sleep
📆 11 – 13 March 2025
📍 India Habitat Centre, Lodhi Road, New Delhi
🌐 meetings.embo.org/event/25-neu...
⏳ Registration Deadline: 19 January 2025
#EMBOworkshop #Neuroscienceofsleep
Neuroscience of Sleep
Sleep science is at an exciting juncture. The realization that sleep is near universal among animals has revolutionized the field. The ubiquity of sleep extends to the discovery of different sleep st…
meetings.embo.org
January 21, 2025 at 6:53 PM
Thanks to everyone who applied. Applications are now closed. Please follow the account quoted here for updates!
Reposted by Krishna Melnattur
Eleanor Maguire, who died 4 January at age 54, pioneered the famous London taxi-driver study and naturalistic approaches for studying spatial and episodic memory in people.
By @callimcflurry.bsky.social
www.thetransmitter.org/memory/remem...
By @callimcflurry.bsky.social
www.thetransmitter.org/memory/remem...
Remembering Eleanor Maguire, ‘trailblazer’ of human memory
Maguire, mastermind of the famous London taxi-driver study, broadened the field and championed the importance of spatial representations in memory.
www.thetransmitter.org
January 10, 2025 at 10:07 PM
Eleanor Maguire, who died 4 January at age 54, pioneered the famous London taxi-driver study and naturalistic approaches for studying spatial and episodic memory in people.
By @callimcflurry.bsky.social
www.thetransmitter.org/memory/remem...
By @callimcflurry.bsky.social
www.thetransmitter.org/memory/remem...
Re-upping this as the deadline is approaching (Jan 15). The program for this EMBO meeting really is terrific - do apply and do spread the word!
We are super excited for this conference on the Neuroscience of Sleep, 11-13 March 2025, at the India Habitat Centre, New Delhi. The program is terrific and the venue lovely, do apply! Re-skeets appreciated! meetings.embo.org/event/25-neu...
Neuroscience of Sleep
Sleep science is at an exciting juncture. The realization that sleep is near universal among animals has revolutionized the field. The ubiquity of sleep extends to the discovery of different sleep st…
meetings.embo.org
January 9, 2025 at 4:57 AM
Re-upping this as the deadline is approaching (Jan 15). The program for this EMBO meeting really is terrific - do apply and do spread the word!
Reposted by Krishna Melnattur
Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus
Mice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal synapse number, seizure susceptibility, neuronal and astrocytic gene expression
www.nature.com/articles/s41...
Mice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal synapse number, seizure susceptibility, neuronal and astrocytic gene expression
www.nature.com/articles/s41...
Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus - Nature Neuroscience
Microglia are proposed to have a role in brain development through synaptic engulfment and paracrine signaling. O’Keeffe et al. show that certain neurodevelopmental processes attributed to microglia c...
www.nature.com
January 7, 2025 at 2:41 PM
Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus
Mice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal synapse number, seizure susceptibility, neuronal and astrocytic gene expression
www.nature.com/articles/s41...
Mice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal synapse number, seizure susceptibility, neuronal and astrocytic gene expression
www.nature.com/articles/s41...
We are super excited for this conference on the Neuroscience of Sleep, 11-13 March 2025, at the India Habitat Centre, New Delhi. The program is terrific and the venue lovely, do apply! Re-skeets appreciated! meetings.embo.org/event/25-neu...
Neuroscience of Sleep
Sleep science is at an exciting juncture. The realization that sleep is near universal among animals has revolutionized the field. The ubiquity of sleep extends to the discovery of different sleep st…
meetings.embo.org
December 13, 2024 at 3:01 PM
We are super excited for this conference on the Neuroscience of Sleep, 11-13 March 2025, at the India Habitat Centre, New Delhi. The program is terrific and the venue lovely, do apply! Re-skeets appreciated! meetings.embo.org/event/25-neu...
Reposted by Krishna Melnattur
We're hiring! Please share!
Exciting opportunities for #PhD students, #postdocs, and #research assistants to join our team in exploring how the brain prioritizes actions in conflict.
#Neuroscience #Drosophila
Interested? Reach out! rezavallab.org
Exciting opportunities for #PhD students, #postdocs, and #research assistants to join our team in exploring how the brain prioritizes actions in conflict.
#Neuroscience #Drosophila
Interested? Reach out! rezavallab.org
November 15, 2024 at 7:09 PM
We're hiring! Please share!
Exciting opportunities for #PhD students, #postdocs, and #research assistants to join our team in exploring how the brain prioritizes actions in conflict.
#Neuroscience #Drosophila
Interested? Reach out! rezavallab.org
Exciting opportunities for #PhD students, #postdocs, and #research assistants to join our team in exploring how the brain prioritizes actions in conflict.
#Neuroscience #Drosophila
Interested? Reach out! rezavallab.org
Reposted by Krishna Melnattur
Our latest discovery of “lowest recorded temperature for eukaryotic cell motility” going all the way down to -15deg C. Come for the crazy cold Arctic & stay for diatoms. Will write longer thread - but enjoy video below of diatoms gliding on frozen ice surfaces. Congrats @zqing.bsky.social & team.
November 21, 2024 at 10:36 AM
Our latest discovery of “lowest recorded temperature for eukaryotic cell motility” going all the way down to -15deg C. Come for the crazy cold Arctic & stay for diatoms. Will write longer thread - but enjoy video below of diatoms gliding on frozen ice surfaces. Congrats @zqing.bsky.social & team.
Reposted by Krishna Melnattur
Happy Fly Day, everyone! On 11/18 (and every day, really), we celebrate this amazing Drosophila model system!
November 18, 2024 at 4:30 PM
Happy Fly Day, everyone! On 11/18 (and every day, really), we celebrate this amazing Drosophila model system!