Max Korbmacher
@maxkorbmacher.bsky.social
Imaging neuroscientist.
Brain (bio)markers, big data, MRI, meta & open/better science. Views are my own.
Brain (bio)markers, big data, MRI, meta & open/better science. Views are my own.
Ren, J., Zhang, W., Dahmani, L. et al. Parkinson’s disease as a somato-cognitive action network disorder. Nature (2026). doi.org/10.1038/s415...
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
doi.org
February 9, 2026 at 8:36 AM
Ren, J., Zhang, W., Dahmani, L. et al. Parkinson’s disease as a somato-cognitive action network disorder. Nature (2026). doi.org/10.1038/s415...
Reposted by Max Korbmacher
New paper in Imaging Neuroscience by James D. Kent, Alejandro de la Vega, et al:
Neurosynth Compose: A web-based platform for flexible and reproducible neuroimaging meta-analysis
doi.org/10.1162/IMAG...
Neurosynth Compose: A web-based platform for flexible and reproducible neuroimaging meta-analysis
doi.org/10.1162/IMAG...
January 29, 2026 at 12:11 PM
New paper in Imaging Neuroscience by James D. Kent, Alejandro de la Vega, et al:
Neurosynth Compose: A web-based platform for flexible and reproducible neuroimaging meta-analysis
doi.org/10.1162/IMAG...
Neurosynth Compose: A web-based platform for flexible and reproducible neuroimaging meta-analysis
doi.org/10.1162/IMAG...
Would be great to make migraine meds obsolete for rTMS responders. Q is whether the classification into responders can be done with cheaper means than fMRI...
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Prospective open-label trial of personalised connectivity-guided transcranial magnetic stimulation therapy for migraine - The Journal of Headache and Pain
The Journal of Headache and Pain - Migraine is a leading cause of disability worldwide, affecting hundreds of millions of individuals. Repetitive transcranial magnetic stimulation (rTMS) offers a...
link.springer.com
January 24, 2026 at 10:50 PM
Would be great to make migraine meds obsolete for rTMS responders. Q is whether the classification into responders can be done with cheaper means than fMRI...
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Multimodal meta-analysis of brain integrity in disorders of consciousness
A Sala, M Meys, N Alnagger, N Beliy, S Abagnale… - 2026
scholar.google.com/scholar_url?...
A Sala, M Meys, N Alnagger, N Beliy, S Abagnale… - 2026
scholar.google.com/scholar_url?...
scholar.google.com
January 11, 2026 at 1:46 PM
Multimodal meta-analysis of brain integrity in disorders of consciousness
A Sala, M Meys, N Alnagger, N Beliy, S Abagnale… - 2026
scholar.google.com/scholar_url?...
A Sala, M Meys, N Alnagger, N Beliy, S Abagnale… - 2026
scholar.google.com/scholar_url?...
Reposted by Max Korbmacher
New post!
There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost.
Medical breakthroughs in 2025. Plus a serious note at the end.
www.scientificdiscovery.dev/p/medical-br...
There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost.
Medical breakthroughs in 2025. Plus a serious note at the end.
www.scientificdiscovery.dev/p/medical-br...
Medical breakthroughs in 2025
... and a happy new year.
www.scientificdiscovery.dev
December 28, 2025 at 6:37 PM
New post!
There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost.
Medical breakthroughs in 2025. Plus a serious note at the end.
www.scientificdiscovery.dev/p/medical-br...
There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost.
Medical breakthroughs in 2025. Plus a serious note at the end.
www.scientificdiscovery.dev/p/medical-br...
Sex‐Modified Effects of APOE‐ε4 on Spatial Patterns of Brain Atrophy: A Multi‐cohort Study
Zhang et al
doi.org/10.1002/alz7...
Zhang et al
doi.org/10.1002/alz7...
doi.org
December 30, 2025 at 11:10 AM
Sex‐Modified Effects of APOE‐ε4 on Spatial Patterns of Brain Atrophy: A Multi‐cohort Study
Zhang et al
doi.org/10.1002/alz7...
Zhang et al
doi.org/10.1002/alz7...
Seems like gold for the Computational neuroscientists and data farmers among us:
BrainScape: An open-source framework for integrating and preprocessing anatomical MRI datasets
Muhammad Nabi Yasinzai, Remika Mito, Mangor Pedersen
doi.org/10.1162/IMAG...
BrainScape: An open-source framework for integrating and preprocessing anatomical MRI datasets
Muhammad Nabi Yasinzai, Remika Mito, Mangor Pedersen
doi.org/10.1162/IMAG...
BrainScape: An open-source framework for integrating and preprocessing anatomical MRI datasets
Abstract. MRI has revolutionized our ability to investigate and understand brain structure and function in health and disease. A large amount of MRI data is widely available to researchers, both from ...
doi.org
December 24, 2025 at 11:59 AM
Seems like gold for the Computational neuroscientists and data farmers among us:
BrainScape: An open-source framework for integrating and preprocessing anatomical MRI datasets
Muhammad Nabi Yasinzai, Remika Mito, Mangor Pedersen
doi.org/10.1162/IMAG...
BrainScape: An open-source framework for integrating and preprocessing anatomical MRI datasets
Muhammad Nabi Yasinzai, Remika Mito, Mangor Pedersen
doi.org/10.1162/IMAG...
Are tele-neuropsychology and in-person assessment scores meaningfully different? A systematic review and meta-analysis
Jessica I. Alva et al
doi.org/10.1080/1385...
Jessica I. Alva et al
doi.org/10.1080/1385...
Are tele-neuropsychology and in-person assessment scores meaningfully different? A systematic review and meta-analysis
Objectives: Despite growing evidence supporting tele-neuropsychology (teleNP), clinicians have voiced concerns about comparability to traditional in-person testing and the limited availability of t...
doi.org
December 24, 2025 at 11:56 AM
Are tele-neuropsychology and in-person assessment scores meaningfully different? A systematic review and meta-analysis
Jessica I. Alva et al
doi.org/10.1080/1385...
Jessica I. Alva et al
doi.org/10.1080/1385...
Reposted by Max Korbmacher
"Grassroots networks can help implement and harmonize open research efforts", by @agataboch.bsky.social, @tkalan.bsky.social, @maxkorbmacher.bsky.social, Lewend Mayiwar, @julienmayor.bsky.social & @dsquintana.bsky.social - doi.org/10.7557/11.8....
December 23, 2025 at 2:24 PM
"Grassroots networks can help implement and harmonize open research efforts", by @agataboch.bsky.social, @tkalan.bsky.social, @maxkorbmacher.bsky.social, Lewend Mayiwar, @julienmayor.bsky.social & @dsquintana.bsky.social - doi.org/10.7557/11.8....
Reposted by Max Korbmacher
We're delighted to welcome TWO new diamond-OA PCI RR-friendly journals
Registered Reports in Linguistics, ed. by @scoretta.bsky.social ky.social & @jess-hampton.bsky.social
+
Replication Research @r2journal.bsky.social ed. by @aufdroeseler.bsky.social & team
rr.peercommunityin.org/about/pci_rr...
Registered Reports in Linguistics, ed. by @scoretta.bsky.social ky.social & @jess-hampton.bsky.social
+
Replication Research @r2journal.bsky.social ed. by @aufdroeseler.bsky.social & team
rr.peercommunityin.org/about/pci_rr...
December 15, 2025 at 12:18 PM
We're delighted to welcome TWO new diamond-OA PCI RR-friendly journals
Registered Reports in Linguistics, ed. by @scoretta.bsky.social ky.social & @jess-hampton.bsky.social
+
Replication Research @r2journal.bsky.social ed. by @aufdroeseler.bsky.social & team
rr.peercommunityin.org/about/pci_rr...
Registered Reports in Linguistics, ed. by @scoretta.bsky.social ky.social & @jess-hampton.bsky.social
+
Replication Research @r2journal.bsky.social ed. by @aufdroeseler.bsky.social & team
rr.peercommunityin.org/about/pci_rr...
Reposted by Max Korbmacher
Hello world! Follow this account to receive announcements, invitations for open peer review, and publications from Replication Research.
November 25, 2025 at 3:59 PM
Hello world! Follow this account to receive announcements, invitations for open peer review, and publications from Replication Research.
Brain-age models with lower age prediction accuracy have higher sensitivity for disease detection
Marc-Andre Schulz, Nys Tjade Siegel, Kerstin Ritter
journals.plos.org/plosbiology/...
Marc-Andre Schulz, Nys Tjade Siegel, Kerstin Ritter
journals.plos.org/plosbiology/...
Brain-age models with lower age prediction accuracy have higher sensitivity for disease detection
There is increasing interest in developing imaging-based models to characterize 'brain-age', but how accurate are these for predicting neurological disease? This study shows that simpler models, which...
journals.plos.org
November 19, 2025 at 9:55 PM
Brain-age models with lower age prediction accuracy have higher sensitivity for disease detection
Marc-Andre Schulz, Nys Tjade Siegel, Kerstin Ritter
journals.plos.org/plosbiology/...
Marc-Andre Schulz, Nys Tjade Siegel, Kerstin Ritter
journals.plos.org/plosbiology/...
Reposted by Max Korbmacher
Is the “standard workflow” holding back fMRI analysis?
Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die.
Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die.
November 18, 2025 at 10:13 PM
Is the “standard workflow” holding back fMRI analysis?
Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die.
Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die.
Reposted by Max Korbmacher
Smeland, O.B., Kutrolli, G., Bahrami, S. et al. A genome-wide analysis of the shared genetic risk architecture of complex neurological and psychiatric disorders. Nat Neurosci (2025). doi.org/10.1038/s415...
A genome-wide analysis of the shared genetic risk architecture of complex neurological and psychiatric disorders - Nature Neuroscience
Smeland et al. demonstrate greater genetic overlap between neurological and psychiatric disorders than previously recognized, along with diverse neurobiological associations. The findings support a mo...
doi.org
November 14, 2025 at 7:07 AM
Smeland, O.B., Kutrolli, G., Bahrami, S. et al. A genome-wide analysis of the shared genetic risk architecture of complex neurological and psychiatric disorders. Nat Neurosci (2025). doi.org/10.1038/s415...
Forskere skjuler nullfunn – koster samfunnet milliarder share.google/jgj4BlIEzVl4...
Forskere skjuler nullfunn – koster samfunnet milliarder
De fleste forskere sier de mener det er viktig å dele negative resultater, men langt færre gjør det i praksis. En ny undersøkelse fra Springer Nature viser at 98 prosent av forskerne er enige i at nul...
share.google
November 13, 2025 at 9:19 PM
Forskere skjuler nullfunn – koster samfunnet milliarder share.google/jgj4BlIEzVl4...
Reposted by Max Korbmacher
It's spooky season, so what better way to spend it than getting horrified by common statistical mistakes? A delightful dark read. It is great to follow the paper's development with reviewers' comments & authors' responses. By Tamar Makin from @plasticity-lab.bsky.social & Jean-Jacques Orban de Xivry
Science Forum: Ten common statistical mistakes to watch out for when writing or reviewing a manuscript
What can authors and reviewers do to keep common statistical mistakes out of the literature?
elifesciences.org
October 30, 2025 at 8:26 PM
It's spooky season, so what better way to spend it than getting horrified by common statistical mistakes? A delightful dark read. It is great to follow the paper's development with reviewers' comments & authors' responses. By Tamar Makin from @plasticity-lab.bsky.social & Jean-Jacques Orban de Xivry
Reposted by Max Korbmacher
New paper in Imaging Neuroscience by Adam M. Wright, Qiuting Wen, et al:
An fMRI approach to assess intracranial arterial-to-venous cardiac pulse delay in aging
doi.org/10.1162/IMAG...
An fMRI approach to assess intracranial arterial-to-venous cardiac pulse delay in aging
doi.org/10.1162/IMAG...
October 31, 2025 at 2:08 AM
New paper in Imaging Neuroscience by Adam M. Wright, Qiuting Wen, et al:
An fMRI approach to assess intracranial arterial-to-venous cardiac pulse delay in aging
doi.org/10.1162/IMAG...
An fMRI approach to assess intracranial arterial-to-venous cardiac pulse delay in aging
doi.org/10.1162/IMAG...
Reposted by Max Korbmacher
Sharing our new paper in Brain Communications ➡️ doi.org/10.1093/brai...
We show that structural connectivity, as measured by high-resolution diffusion-weighted MRI, improved the ability to predict age-related alterations in brain function and cognition, relative to standard spatial resolution.
We show that structural connectivity, as measured by high-resolution diffusion-weighted MRI, improved the ability to predict age-related alterations in brain function and cognition, relative to standard spatial resolution.
October 16, 2025 at 12:51 PM
Sharing our new paper in Brain Communications ➡️ doi.org/10.1093/brai...
We show that structural connectivity, as measured by high-resolution diffusion-weighted MRI, improved the ability to predict age-related alterations in brain function and cognition, relative to standard spatial resolution.
We show that structural connectivity, as measured by high-resolution diffusion-weighted MRI, improved the ability to predict age-related alterations in brain function and cognition, relative to standard spatial resolution.
Prado, P., Medel, V., Gonzalez-Gomez, R. et al. The BrainLat project, a multimodal neuroimaging dataset of neurodegeneration from underrepresented backgrounds. Sci Data 10, 889 (2023). doi.org/10.1038/s415...
The BrainLat project, a multimodal neuroimaging dataset of neurodegeneration from underrepresented backgrounds - Scientific Data
Scientific Data - The BrainLat project, a multimodal neuroimaging dataset of neurodegeneration from underrepresented backgrounds
doi.org
October 26, 2025 at 6:15 PM
Prado, P., Medel, V., Gonzalez-Gomez, R. et al. The BrainLat project, a multimodal neuroimaging dataset of neurodegeneration from underrepresented backgrounds. Sci Data 10, 889 (2023). doi.org/10.1038/s415...
Reposted by Max Korbmacher
12 waves!
Individual Differences in Developmental Trajectories of Global and Subcortical Brain Volumes Between Late Childhood and Late Adolescence: Findings From a 12-Wave Neuroimaging Study
Human Brain Mapping | Neuroimaging Journal | Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Individual Differences in Developmental Trajectories of Global and Subcortical Brain Volumes Between Late Childhood and Late Adolescence: Findings From a 12-Wave Neuroimaging Study
Human Brain Mapping | Neuroimaging Journal | Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Individual Differences in Developmental Trajectories of Global and Subcortical Brain Volumes Between Late Childhood and Late Adolescence: Findings From a 12‐Wave Neuroimaging Study
Global and subcortical brain volumes demonstrate sex-specific increases (white matter, hippocampus, amygdala, and pallidum) and decreases (cortical grey matter, total brain volume, caudate, putamen, ...
onlinelibrary.wiley.com
October 14, 2025 at 10:00 PM
12 waves!
Individual Differences in Developmental Trajectories of Global and Subcortical Brain Volumes Between Late Childhood and Late Adolescence: Findings From a 12-Wave Neuroimaging Study
Human Brain Mapping | Neuroimaging Journal | Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Individual Differences in Developmental Trajectories of Global and Subcortical Brain Volumes Between Late Childhood and Late Adolescence: Findings From a 12-Wave Neuroimaging Study
Human Brain Mapping | Neuroimaging Journal | Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Reposted by Max Korbmacher
Identifying brain functional subtypes and corresponding task performance profiles in autism spectrum disorder | Molecular Psychiatry www.nature.com/articles/s41...
Identifying brain functional subtypes and corresponding task performance profiles in autism spectrum disorder - Molecular Psychiatry
Molecular Psychiatry - Identifying brain functional subtypes and corresponding task performance profiles in autism spectrum disorder
www.nature.com
October 19, 2025 at 9:05 PM
Identifying brain functional subtypes and corresponding task performance profiles in autism spectrum disorder | Molecular Psychiatry www.nature.com/articles/s41...
Reposted by Max Korbmacher
New paper in Imaging Neuroscience by František Váša, Steven C.R. Williams, et al:
Ultra-low-field brain MRI morphometry: Test–retest reliability and correspondence to high-field MRI
doi.org/10.1162/IMAG...
Ultra-low-field brain MRI morphometry: Test–retest reliability and correspondence to high-field MRI
doi.org/10.1162/IMAG...
October 16, 2025 at 3:26 AM
New paper in Imaging Neuroscience by František Váša, Steven C.R. Williams, et al:
Ultra-low-field brain MRI morphometry: Test–retest reliability and correspondence to high-field MRI
doi.org/10.1162/IMAG...
Ultra-low-field brain MRI morphometry: Test–retest reliability and correspondence to high-field MRI
doi.org/10.1162/IMAG...
Reposted by Max Korbmacher
It’s not the thought that counts: Allostasis at the core of brain function
www.cell.com/neuron/fullt...
#neuroscience
www.cell.com/neuron/fullt...
#neuroscience
It’s not the thought that counts: Allostasis at the core of brain function
The authors review evidence that the primary function of the brain, supported by distributed
neural systems, is the predictive regulation of physiology (i.e., allostasis). An
example from Alzheimer’s ...
www.cell.com
October 18, 2025 at 1:54 PM
It’s not the thought that counts: Allostasis at the core of brain function
www.cell.com/neuron/fullt...
#neuroscience
www.cell.com/neuron/fullt...
#neuroscience