Mathurin Dorel
@mathsrish.bsky.social
Cancer systems biologist. I'm poking at cancer cells to model how they work in details. #perturbation #model #highthroughout #targetedtherapy
ORCID: 0000-0002-1663-2075
ORCID: 0000-0002-1663-2075
Pinned
Mathurin Dorel
@mathsrish.bsky.social
· Mar 17
Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants - KFF Health News
Two senior scientists say National Institutes of Health officials advised them to remove references to mRNA vaccines in grant applications, and they fear the Trump administration will abandon a promis...
kffhealthnews.org
And now the US gov has started a war on vaccines...
kffhealthnews.org/news/article...
It's becoming more urgent for Europe to increase funding massively to enable thousands of US researcher to move and continue their research in Europe.
@elisabeth-borne.bsky.social
@oezdemir.de @fpetit.bsky.social
kffhealthnews.org/news/article...
It's becoming more urgent for Europe to increase funding massively to enable thousands of US researcher to move and continue their research in Europe.
@elisabeth-borne.bsky.social
@oezdemir.de @fpetit.bsky.social
Reposted by Mathurin Dorel
![4-panel vertical comic. (1) 100 Years Ago [two people standing next to bicycle with small car nearby] PERSON 1: It’s too dangerous riding a bike with these cars around. I should get a car, too. (2) 50 Years Ago [two people between smaller car and bigger car] PERSON 2 with short hair: Small cars are less safe in collisions with larger vehicles, so I should get a bigger one. (3) Today [two people between big car and even bigger car] PERSON 1: Everyone has huge SUVs now. If I don’t get the biggest one, I’m putting my family at risk. (4) Soon [two people next to large armored car with spiked clubs attached] PERSON 2: If I don’t install more whirling spike clubs, I’ll be destroyed by all the other drivers who...](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreiby6can6k76yzfmv2czxs4pu2l7zie7bqbrpswi7h3ifmiadkuqvu@jpeg)
Reposted by Mathurin Dorel
You are under no obligation to mourn the death of people who would’ve celebrated yours.
September 10, 2025 at 8:56 PM
You are under no obligation to mourn the death of people who would’ve celebrated yours.
Anyone knows more about the new Russian cancer vaccine ?
The most reliable info I could find in English is that it's 4 viruses. The new press releases also sound like the full treatment involves personalized mRNA and that it was tested in 48 patients with 100% success
new.nmicr.ru/en/pacientam...
The most reliable info I could find in English is that it's 4 viruses. The new press releases also sound like the full treatment involves personalized mRNA and that it was tested in 48 patients with 100% success
new.nmicr.ru/en/pacientam...
Cancer Vaccine - biotech solutions in the fight against cancer diseases
Oncolytic and personalized vaccines - clinical trials and patient enrollment for Phase I begins as early as late 2024, early 2025
new.nmicr.ru
September 8, 2025 at 10:09 AM
Anyone knows more about the new Russian cancer vaccine ?
The most reliable info I could find in English is that it's 4 viruses. The new press releases also sound like the full treatment involves personalized mRNA and that it was tested in 48 patients with 100% success
new.nmicr.ru/en/pacientam...
The most reliable info I could find in English is that it's 4 viruses. The new press releases also sound like the full treatment involves personalized mRNA and that it was tested in 48 patients with 100% success
new.nmicr.ru/en/pacientam...
Yeah, LLM suck at data retrieval...
(Tried to be lazy today)
(Tried to be lazy today)
August 21, 2025 at 3:13 PM
Yeah, LLM suck at data retrieval...
(Tried to be lazy today)
(Tried to be lazy today)
Reposted by Mathurin Dorel
Je m’arrête là dessus un instant, car je vois souvent cette étude citée pour dire qu’en gros le recours à la clim augmenterait systématiquement la température de la ville de 2 à 3°C et que c’est bien la preuve que c’est pas une solution.
Ce qui est complètement partiel et trompeur.
Ce qui est complètement partiel et trompeur.
August 15, 2025 at 10:29 PM
Je m’arrête là dessus un instant, car je vois souvent cette étude citée pour dire qu’en gros le recours à la clim augmenterait systématiquement la température de la ville de 2 à 3°C et que c’est bien la preuve que c’est pas une solution.
Ce qui est complètement partiel et trompeur.
Ce qui est complètement partiel et trompeur.
Reposted by Mathurin Dorel
No, you did not give those of us who happened to look like the people who bombed Pearl Harbor any due process. And that was profoundly wrong. It destroyed our lives.
August 8, 2025 at 6:46 PM
No, you did not give those of us who happened to look like the people who bombed Pearl Harbor any due process. And that was profoundly wrong. It destroyed our lives.
Great model for both science and the journals viability.
Everyone just need to convince philanthropists to fund their favorite journals and everybody wins.
Everyone just need to convince philanthropists to fund their favorite journals and everybody wins.
The Royal Society is joining a growing wave of scientific publishers that are implementing the 'subscribe to open' model
go.nature.com/3UPt7b3
go.nature.com/3UPt7b3
UK Royal Society adopts ‘subscribe to open’ publishing model
Nature - Eight of its journals will publish papers open-access each year they earn sufficient library revenue.
go.nature.com
August 9, 2025 at 8:38 AM
Great model for both science and the journals viability.
Everyone just need to convince philanthropists to fund their favorite journals and everybody wins.
Everyone just need to convince philanthropists to fund their favorite journals and everybody wins.
Reposted by Mathurin Dorel
If I could change one thing about #ScientificPublishing I'd ask funding bodies to stipulate all work they fund be published in non-profit journals.
The knock-on effects would alleviate most of the strain on #AcademicSky.
This isn't hard. It's big, but actually, it's pretty easy.
1/n
The knock-on effects would alleviate most of the strain on #AcademicSky.
This isn't hard. It's big, but actually, it's pretty easy.
1/n
The strain on scientific publishing
Abstract. Scientists are increasingly overwhelmed by the volume of articles being published. The total number of articles indexed in Scopus and Web of Science has grown exponentially in recent years; ...
direct.mit.edu
August 4, 2025 at 8:10 AM
If I could change one thing about #ScientificPublishing I'd ask funding bodies to stipulate all work they fund be published in non-profit journals.
The knock-on effects would alleviate most of the strain on #AcademicSky.
This isn't hard. It's big, but actually, it's pretty easy.
1/n
The knock-on effects would alleviate most of the strain on #AcademicSky.
This isn't hard. It's big, but actually, it's pretty easy.
1/n
But if falls to less than 5% in winter, when Europe needs the most electricity.
Notice on the left graph how wind, *gas* and *coal* take over.
Europe needs to scale up nuclear and batteries big time, for the climate and for it's energy independence. (Hydro scale up is not possible sadly).
Notice on the left graph how wind, *gas* and *coal* take over.
Europe needs to scale up nuclear and batteries big time, for the climate and for it's energy independence. (Hydro scale up is not possible sadly).
NEW | Solar power was the EU’s biggest power source in June 2025 ☀️
For the first time, solar ranked first among all power sources, producing 22.1% of the EU’s power ahead of nuclear at 21.8%.
Coal power fell to a record low 6.1% in sixth place.
For the first time, solar ranked first among all power sources, producing 22.1% of the EU’s power ahead of nuclear at 21.8%.
Coal power fell to a record low 6.1% in sixth place.
July 10, 2025 at 9:52 AM
But if falls to less than 5% in winter, when Europe needs the most electricity.
Notice on the left graph how wind, *gas* and *coal* take over.
Europe needs to scale up nuclear and batteries big time, for the climate and for it's energy independence. (Hydro scale up is not possible sadly).
Notice on the left graph how wind, *gas* and *coal* take over.
Europe needs to scale up nuclear and batteries big time, for the climate and for it's energy independence. (Hydro scale up is not possible sadly).
Reposted by Mathurin Dorel
La #ScienceTailleXXelles revient en lle-de-France ! 🤩
Nos 21 nouvelles ambassadrices sont mécatronicienne, archéobotaniste, exobiologiste, ou encore informaticienne👩🔬
Chercheuses, doctorantes, ingénieures et techniciennes, toutes ont à cœur de montrer que la science se conjugue aussi au féminin !
⤵️
Nos 21 nouvelles ambassadrices sont mécatronicienne, archéobotaniste, exobiologiste, ou encore informaticienne👩🔬
Chercheuses, doctorantes, ingénieures et techniciennes, toutes ont à cœur de montrer que la science se conjugue aussi au féminin !
⤵️
June 23, 2025 at 10:40 AM
La #ScienceTailleXXelles revient en lle-de-France ! 🤩
Nos 21 nouvelles ambassadrices sont mécatronicienne, archéobotaniste, exobiologiste, ou encore informaticienne👩🔬
Chercheuses, doctorantes, ingénieures et techniciennes, toutes ont à cœur de montrer que la science se conjugue aussi au féminin !
⤵️
Nos 21 nouvelles ambassadrices sont mécatronicienne, archéobotaniste, exobiologiste, ou encore informaticienne👩🔬
Chercheuses, doctorantes, ingénieures et techniciennes, toutes ont à cœur de montrer que la science se conjugue aussi au féminin !
⤵️
Nice thing about having a thermal camera on your phone is that you can quantify your suffering during a heat wave.
You can also check if your insulation measures are working and how much worse it could get which is nice I guess.
You can also check if your insulation measures are working and how much worse it could get which is nice I guess.
July 2, 2025 at 1:26 PM
Nice thing about having a thermal camera on your phone is that you can quantify your suffering during a heat wave.
You can also check if your insulation measures are working and how much worse it could get which is nice I guess.
You can also check if your insulation measures are working and how much worse it could get which is nice I guess.
Poland knows where it's at!
On the final day of Poland’s EU Presidency, 🇵🇱 Deputy Minister for Science Andrzej Szeptycki @szeptycki.bsky.social argues that Europe’s global standing depends on stronger investment in research and innovation.
🧠 “Strategic sovereignty starts with research”
Read the piece 👉 europa.eu/!6BkvPj
🧠 “Strategic sovereignty starts with research”
Read the piece 👉 europa.eu/!6BkvPj
Europe’s path to competitiveness: The strategic role of research and innovation
By Andrzej Szeptycki
europa.eu
June 30, 2025 at 9:12 AM
Poland knows where it's at!
Reposted by Mathurin Dorel
On the final day of Poland’s EU Presidency, 🇵🇱 Deputy Minister for Science Andrzej Szeptycki @szeptycki.bsky.social argues that Europe’s global standing depends on stronger investment in research and innovation.
🧠 “Strategic sovereignty starts with research”
Read the piece 👉 europa.eu/!6BkvPj
🧠 “Strategic sovereignty starts with research”
Read the piece 👉 europa.eu/!6BkvPj
Europe’s path to competitiveness: The strategic role of research and innovation
By Andrzej Szeptycki
europa.eu
June 30, 2025 at 7:53 AM
On the final day of Poland’s EU Presidency, 🇵🇱 Deputy Minister for Science Andrzej Szeptycki @szeptycki.bsky.social argues that Europe’s global standing depends on stronger investment in research and innovation.
🧠 “Strategic sovereignty starts with research”
Read the piece 👉 europa.eu/!6BkvPj
🧠 “Strategic sovereignty starts with research”
Read the piece 👉 europa.eu/!6BkvPj
Reposted by Mathurin Dorel
Good read. My fav: "If I could distill my scientific life into five words, they would read: “I regret to inform you”"... www.embopress.org/doi/full/10....
A career in science requires a thick skin | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
June 30, 2025 at 7:26 AM
Good read. My fav: "If I could distill my scientific life into five words, they would read: “I regret to inform you”"... www.embopress.org/doi/full/10....
Reposted by Mathurin Dorel
Vaccination schedules on the CDC website have already started changing under RFK Jr. So we published a guide to the evidence-based vaccine recommendations in place *before* all 17 members of the advisory panel were abruptly dismissed by the new admin. www.scientificamerican.com/article/see-... 🧪
Here’s Your Cheat Sheet for Vaccine Recommendations Backed by Science
These graphics will guide you through science-based vaccine guidelines for children and adults
www.scientificamerican.com
June 25, 2025 at 11:49 AM
Vaccination schedules on the CDC website have already started changing under RFK Jr. So we published a guide to the evidence-based vaccine recommendations in place *before* all 17 members of the advisory panel were abruptly dismissed by the new admin. www.scientificamerican.com/article/see-... 🧪
Reposted by Mathurin Dorel
An immigration crackdown makes the United States less attractive. Where should you hold your next conference?
https://go.nature.com/407qJ2w
https://go.nature.com/407qJ2w
Where is the best place to hold a scientific conference right now?
An immigration crackdown makes the United States less attractive. These locations could steal its crown and make conferences more globally inclusive.
go.nature.com
June 20, 2025 at 9:02 AM
An immigration crackdown makes the United States less attractive. Where should you hold your next conference?
https://go.nature.com/407qJ2w
https://go.nature.com/407qJ2w
You regular reminder that European science does not lack ideas, it lacks fundings.
Congratulations! The new Advanced Grant winners are great news.
But yet again, many scientists - around 260 - with ground-breaking ideas were rated as excellent, but remained unfunded due to a lack of funds at the ERC. Hope that more funding will be available in the future!
But yet again, many scientists - around 260 - with ground-breaking ideas were rated as excellent, but remained unfunded due to a lack of funds at the ERC. Hope that more funding will be available in the future!
📣 Good news: 281 top researchers have just won ERC Advanced Grants!
The new funding, worth nearly €721 million, is part of the 🇪🇺 EU’s #HorizonEurope programme.
Find out more 👉 europa.eu/!JYKxkD
#ERCAdG #FrontierResearch @ec.europa.eu
The new funding, worth nearly €721 million, is part of the 🇪🇺 EU’s #HorizonEurope programme.
Find out more 👉 europa.eu/!JYKxkD
#ERCAdG #FrontierResearch @ec.europa.eu
June 18, 2025 at 8:39 AM
You regular reminder that European science does not lack ideas, it lacks fundings.
Reposted by Mathurin Dorel
Weizmann Institute rn
June 15, 2025 at 6:22 AM
Weizmann Institute rn
Reposted by Mathurin Dorel
I also reject the notion that "most biomedical literature is unreliable/untrue." This is simply not the case. The vast majority of biomedical research is so reliable we don't even think about it. And yes, some studies and even subfields have issues, but let's acknowledge all the things that work. 🧵
"Create a journal for replication work". 🙄
This comes up time again as if there aren't existing places to put replications. PLOSOne will taken them, plenty of other journals will, and bioRxiv has had an article type called "Confirmatory Results" since we launched in 2013!
This comes up time again as if there aren't existing places to put replications. PLOSOne will taken them, plenty of other journals will, and bioRxiv has had an article type called "Confirmatory Results" since we launched in 2013!
JB plans for NIH: give grants for replication work. Create journal for replication work. Evaluate on metrics including efforts to facilitate replication, not just influence.
AH raises: funding this will take money from somewhere else. JB kind of shrugs this off but...FY2026 budget is a 40% cut.
AH raises: funding this will take money from somewhere else. JB kind of shrugs this off but...FY2026 budget is a 40% cut.
June 10, 2025 at 2:29 PM
I also reject the notion that "most biomedical literature is unreliable/untrue." This is simply not the case. The vast majority of biomedical research is so reliable we don't even think about it. And yes, some studies and even subfields have issues, but let's acknowledge all the things that work. 🧵
Reposted by Mathurin Dorel
It’s becoming clearer and clearer that universities have to produce their own open models.
If we can’t pull that off, we may continue to provide cafeterias and climbing walls — but the key decisions about learning will take place elsewhere.
If we can’t pull that off, we may continue to provide cafeterias and climbing walls — but the key decisions about learning will take place elsewhere.
June 7, 2025 at 2:31 PM
It’s becoming clearer and clearer that universities have to produce their own open models.
If we can’t pull that off, we may continue to provide cafeterias and climbing walls — but the key decisions about learning will take place elsewhere.
If we can’t pull that off, we may continue to provide cafeterias and climbing walls — but the key decisions about learning will take place elsewhere.
Seems I'm exhausting my jinx this week (technically last week).
In one back and forth trip I'm getting enough flights cancelled to make a thread about it.
In one back and forth trip I'm getting enough flights cancelled to make a thread about it.
June 2, 2025 at 8:09 PM
Seems I'm exhausting my jinx this week (technically last week).
In one back and forth trip I'm getting enough flights cancelled to make a thread about it.
In one back and forth trip I'm getting enough flights cancelled to make a thread about it.
As I just visited CERN I have to oppose this statement.
But EMBO is a very good second ^^
And I say it as a biologist who regularly interacts with EMBO.
(Also personally I choose Geneva over Heidelberg any day 😍)
But EMBO is a very good second ^^
And I say it as a biologist who regularly interacts with EMBO.
(Also personally I choose Geneva over Heidelberg any day 😍)
June 2, 2025 at 11:51 AM
As I just visited CERN I have to oppose this statement.
But EMBO is a very good second ^^
And I say it as a biologist who regularly interacts with EMBO.
(Also personally I choose Geneva over Heidelberg any day 😍)
But EMBO is a very good second ^^
And I say it as a biologist who regularly interacts with EMBO.
(Also personally I choose Geneva over Heidelberg any day 😍)
Reposted by Mathurin Dorel
🚀We are very pleased to announce that Prof. David Staněk became a member of the European Molecular Biology Organization @embo.org
👏David considers EMBO as "the best thing that European countries have done for science."
👏David considers EMBO as "the best thing that European countries have done for science."
February 18, 2025 at 10:08 AM
🚀We are very pleased to announce that Prof. David Staněk became a member of the European Molecular Biology Organization @embo.org
👏David considers EMBO as "the best thing that European countries have done for science."
👏David considers EMBO as "the best thing that European countries have done for science."
Reposted by Mathurin Dorel
200+ scientists are in the middle of a marathon livestream to show why weather and climate science is so important and needs all our help to continue.
It is here: wclivestream.com/watch
It is here: wclivestream.com/watch
Redirecting to: https://www.youtube.com/@wclivestream/live
wclivestream.com
May 28, 2025 at 11:03 PM
200+ scientists are in the middle of a marathon livestream to show why weather and climate science is so important and needs all our help to continue.
It is here: wclivestream.com/watch
It is here: wclivestream.com/watch
Reposted by Mathurin Dorel
INCREDIBLE !!
Here we are... 😱😱😱
After days of overloading and cracks propagating, Birch Glacier collapsed today at 3.24 pm over Blatten and the dammed Lonza river...
Devastating! 😭
www.letemps.ch/suisse/valai...
Here we are... 😱😱😱
After days of overloading and cracks propagating, Birch Glacier collapsed today at 3.24 pm over Blatten and the dammed Lonza river...
Devastating! 😭
www.letemps.ch/suisse/valai...
May 28, 2025 at 3:09 PM
INCREDIBLE !!
Here we are... 😱😱😱
After days of overloading and cracks propagating, Birch Glacier collapsed today at 3.24 pm over Blatten and the dammed Lonza river...
Devastating! 😭
www.letemps.ch/suisse/valai...
Here we are... 😱😱😱
After days of overloading and cracks propagating, Birch Glacier collapsed today at 3.24 pm over Blatten and the dammed Lonza river...
Devastating! 😭
www.letemps.ch/suisse/valai...