Institute of Molecular Genetics
@imgprague.bsky.social
Public scientific institution, part of the Czech Academy of Sciences. Research in molecular, structure and cell biology, immunology, genomics and bioinformatics.
🚀Open PhD position!
Combine bioinformatics, single-cell and spatial multi-omics, with machine learning to uncover how the vertebrate head evolved.
🧫Laboratory of Transcriptional Regulation is seeking a highly motivated PhD candidate.
Come and join us
🧡APPLY NOW img.cas.cz/phd
Combine bioinformatics, single-cell and spatial multi-omics, with machine learning to uncover how the vertebrate head evolved.
🧫Laboratory of Transcriptional Regulation is seeking a highly motivated PhD candidate.
Come and join us
🧡APPLY NOW img.cas.cz/phd
February 10, 2026 at 10:52 AM
🚀Open PhD position!
Combine bioinformatics, single-cell and spatial multi-omics, with machine learning to uncover how the vertebrate head evolved.
🧫Laboratory of Transcriptional Regulation is seeking a highly motivated PhD candidate.
Come and join us
🧡APPLY NOW img.cas.cz/phd
Combine bioinformatics, single-cell and spatial multi-omics, with machine learning to uncover how the vertebrate head evolved.
🧫Laboratory of Transcriptional Regulation is seeking a highly motivated PhD candidate.
Come and join us
🧡APPLY NOW img.cas.cz/phd
🚀Open PhD position!
Genome instability promotes cancer development. This project will examine metabolic signaling defects to reveal cell vulnerabilities and novel chemotherapeutics.
🧬Laboratory of Cancer Cell Biology is seeking a new team player.
Do you fit?
🧡APPLY NOW img.cas.cz/phd
Genome instability promotes cancer development. This project will examine metabolic signaling defects to reveal cell vulnerabilities and novel chemotherapeutics.
🧬Laboratory of Cancer Cell Biology is seeking a new team player.
Do you fit?
🧡APPLY NOW img.cas.cz/phd
February 9, 2026 at 9:51 AM
🚀Open PhD position!
Genome instability promotes cancer development. This project will examine metabolic signaling defects to reveal cell vulnerabilities and novel chemotherapeutics.
🧬Laboratory of Cancer Cell Biology is seeking a new team player.
Do you fit?
🧡APPLY NOW img.cas.cz/phd
Genome instability promotes cancer development. This project will examine metabolic signaling defects to reveal cell vulnerabilities and novel chemotherapeutics.
🧬Laboratory of Cancer Cell Biology is seeking a new team player.
Do you fit?
🧡APPLY NOW img.cas.cz/phd
🚀Open PhD position!
Join Nenad at IMG and share with us:
💛Experience
🧡Friendship
💙Professionalism
💜PhD community
APPLY NOW: img.cas.cz/phd
Join Nenad at IMG and share with us:
💛Experience
🧡Friendship
💙Professionalism
💜PhD community
APPLY NOW: img.cas.cz/phd
February 4, 2026 at 1:32 PM
🚀Open PhD position!
Join Nenad at IMG and share with us:
💛Experience
🧡Friendship
💙Professionalism
💜PhD community
APPLY NOW: img.cas.cz/phd
Join Nenad at IMG and share with us:
💛Experience
🧡Friendship
💙Professionalism
💜PhD community
APPLY NOW: img.cas.cz/phd
🚀Open PhD position!
Ever wondered how cells polarize during early development?
This PhD project dives into how mechanochemically-driven cell polarization evolves.
🧪 Genomics
🔬 Biophysics
📊 Fitness analysis
Hooked?
🧡APPLY NOW img.cas.cz/phd
Ever wondered how cells polarize during early development?
This PhD project dives into how mechanochemically-driven cell polarization evolves.
🧪 Genomics
🔬 Biophysics
📊 Fitness analysis
Hooked?
🧡APPLY NOW img.cas.cz/phd
February 3, 2026 at 10:42 AM
🚀Open PhD position!
Ever wondered how cells polarize during early development?
This PhD project dives into how mechanochemically-driven cell polarization evolves.
🧪 Genomics
🔬 Biophysics
📊 Fitness analysis
Hooked?
🧡APPLY NOW img.cas.cz/phd
Ever wondered how cells polarize during early development?
This PhD project dives into how mechanochemically-driven cell polarization evolves.
🧪 Genomics
🔬 Biophysics
📊 Fitness analysis
Hooked?
🧡APPLY NOW img.cas.cz/phd
🚀Open PhD position!
Join our newly established Lab of Immunophysiology.
🧪How do lymph nodes maintain immune tolerance? We‘ll study how fibroblastic reticular cells present self-antigens to support Treg maintenance and prevent autoimmunity.
👉Do you know lab work and coding?
🧡APPLY NOW img.cas.cz/phd
Join our newly established Lab of Immunophysiology.
🧪How do lymph nodes maintain immune tolerance? We‘ll study how fibroblastic reticular cells present self-antigens to support Treg maintenance and prevent autoimmunity.
👉Do you know lab work and coding?
🧡APPLY NOW img.cas.cz/phd
January 29, 2026 at 2:32 PM
🚀Open PhD position!
Join our newly established Lab of Immunophysiology.
🧪How do lymph nodes maintain immune tolerance? We‘ll study how fibroblastic reticular cells present self-antigens to support Treg maintenance and prevent autoimmunity.
👉Do you know lab work and coding?
🧡APPLY NOW img.cas.cz/phd
Join our newly established Lab of Immunophysiology.
🧪How do lymph nodes maintain immune tolerance? We‘ll study how fibroblastic reticular cells present self-antigens to support Treg maintenance and prevent autoimmunity.
👉Do you know lab work and coding?
🧡APPLY NOW img.cas.cz/phd
Joining IMG was the right choice 🎉
Read the full interview with our PhD student Kristína Jamrichová www.img.cas.cz/2025/02/8515...
Be like Kristína, join us now!
APPLY HERE img.cas.cz/phd
Read the full interview with our PhD student Kristína Jamrichová www.img.cas.cz/2025/02/8515...
Be like Kristína, join us now!
APPLY HERE img.cas.cz/phd
January 27, 2026 at 9:59 AM
Joining IMG was the right choice 🎉
Read the full interview with our PhD student Kristína Jamrichová www.img.cas.cz/2025/02/8515...
Be like Kristína, join us now!
APPLY HERE img.cas.cz/phd
Read the full interview with our PhD student Kristína Jamrichová www.img.cas.cz/2025/02/8515...
Be like Kristína, join us now!
APPLY HERE img.cas.cz/phd
🚀Open PhD position!
Lab of Cell and Developmental Biology is seeking a new team player.
🤝Join us to study stem cells, DNA repair, and how 💥cancer💥 really starts.
👉We seek independent thinker ready to learn both experimental and computational approaches.
🧡APPLY NOW img.cas.cz/phd
Lab of Cell and Developmental Biology is seeking a new team player.
🤝Join us to study stem cells, DNA repair, and how 💥cancer💥 really starts.
👉We seek independent thinker ready to learn both experimental and computational approaches.
🧡APPLY NOW img.cas.cz/phd
January 26, 2026 at 12:03 PM
🚀Open PhD position!
Lab of Cell and Developmental Biology is seeking a new team player.
🤝Join us to study stem cells, DNA repair, and how 💥cancer💥 really starts.
👉We seek independent thinker ready to learn both experimental and computational approaches.
🧡APPLY NOW img.cas.cz/phd
Lab of Cell and Developmental Biology is seeking a new team player.
🤝Join us to study stem cells, DNA repair, and how 💥cancer💥 really starts.
👉We seek independent thinker ready to learn both experimental and computational approaches.
🧡APPLY NOW img.cas.cz/phd
Join the Laboratory of Haematooncology and study chronic inflammation, aging and blood stem cells🩸
👩🔬👨🔬We seek a highly motivated, enthusiastic and hard-working PhD student with a strong team spirit
🤝We offer a friendly and supportive environment in a state-of-the-art institution
APPLY: img.cas.cz/phd
👩🔬👨🔬We seek a highly motivated, enthusiastic and hard-working PhD student with a strong team spirit
🤝We offer a friendly and supportive environment in a state-of-the-art institution
APPLY: img.cas.cz/phd
January 22, 2026 at 9:46 AM
Join the Laboratory of Haematooncology and study chronic inflammation, aging and blood stem cells🩸
👩🔬👨🔬We seek a highly motivated, enthusiastic and hard-working PhD student with a strong team spirit
🤝We offer a friendly and supportive environment in a state-of-the-art institution
APPLY: img.cas.cz/phd
👩🔬👨🔬We seek a highly motivated, enthusiastic and hard-working PhD student with a strong team spirit
🤝We offer a friendly and supportive environment in a state-of-the-art institution
APPLY: img.cas.cz/phd
Reposted by Institute of Molecular Genetics
Hope for rare anemia patients: Czech scientists create "perfect" mouse model
Researchers from @czphenogenomics.bsky.social @imgprague.bsky.social achieved a breakthrough in understanding Diamond-Blackfan anemia, a severe genetic disease causing anemia and birth defects in children.
bit.ly/4r4dg6I
Researchers from @czphenogenomics.bsky.social @imgprague.bsky.social achieved a breakthrough in understanding Diamond-Blackfan anemia, a severe genetic disease causing anemia and birth defects in children.
bit.ly/4r4dg6I
Rps19R67∆ mutation creates a model of Diamond–Blackfan anemia and reveals downstream mediators of p53 pathway
Diamond–Blackfan anemia (DBA) is a rare bone marrow failure syndrome accompanied by cardiovascular, skeletal, and urogenital abnormalities. Most of the affected individuals carry mutations in ribosom...
onlinelibrary.wiley.com
January 21, 2026 at 12:51 PM
Hope for rare anemia patients: Czech scientists create "perfect" mouse model
Researchers from @czphenogenomics.bsky.social @imgprague.bsky.social achieved a breakthrough in understanding Diamond-Blackfan anemia, a severe genetic disease causing anemia and birth defects in children.
bit.ly/4r4dg6I
Researchers from @czphenogenomics.bsky.social @imgprague.bsky.social achieved a breakthrough in understanding Diamond-Blackfan anemia, a severe genetic disease causing anemia and birth defects in children.
bit.ly/4r4dg6I
💪PhD at IMG is always a good choice.
Join @sindija.s, our student representative, and start enjoying what IMG offers.
🧡PhD Conference, Career Day, Green Swap and much more - come and see!
Wanna help Sindi organizing PhD events?
APPLY NOW ➡ img.cas.cz/phd
Join @sindija.s, our student representative, and start enjoying what IMG offers.
🧡PhD Conference, Career Day, Green Swap and much more - come and see!
Wanna help Sindi organizing PhD events?
APPLY NOW ➡ img.cas.cz/phd
January 21, 2026 at 9:24 AM
💪PhD at IMG is always a good choice.
Join @sindija.s, our student representative, and start enjoying what IMG offers.
🧡PhD Conference, Career Day, Green Swap and much more - come and see!
Wanna help Sindi organizing PhD events?
APPLY NOW ➡ img.cas.cz/phd
Join @sindija.s, our student representative, and start enjoying what IMG offers.
🧡PhD Conference, Career Day, Green Swap and much more - come and see!
Wanna help Sindi organizing PhD events?
APPLY NOW ➡ img.cas.cz/phd
🚀Open PhD position!
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
January 19, 2026 at 10:16 AM
🚀Open PhD position!
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
🤝Join us in Prague!
Browse our open PhD positions at www.img.cas.cz/phd
Join a global team and supportive environment, work with top-notch facilities, and enjoy our IMG community!
➡APPLY NOW!
Browse our open PhD positions at www.img.cas.cz/phd
Join a global team and supportive environment, work with top-notch facilities, and enjoy our IMG community!
➡APPLY NOW!
January 15, 2026 at 9:13 AM
🤝Join us in Prague!
Browse our open PhD positions at www.img.cas.cz/phd
Join a global team and supportive environment, work with top-notch facilities, and enjoy our IMG community!
➡APPLY NOW!
Browse our open PhD positions at www.img.cas.cz/phd
Join a global team and supportive environment, work with top-notch facilities, and enjoy our IMG community!
➡APPLY NOW!
🚀CALL for PhDs just launched🚀
We are accepting applications for the PhD program
🚨APPLY NOW!🚨
📅28. 2. 2026
➡www.img.cas.cz/phd
We are accepting applications for the PhD program
🚨APPLY NOW!🚨
📅28. 2. 2026
➡www.img.cas.cz/phd
January 13, 2026 at 5:46 PM
🚀CALL for PhDs just launched🚀
We are accepting applications for the PhD program
🚨APPLY NOW!🚨
📅28. 2. 2026
➡www.img.cas.cz/phd
We are accepting applications for the PhD program
🚨APPLY NOW!🚨
📅28. 2. 2026
➡www.img.cas.cz/phd
Publication pubmed.ncbi.nlm.nih.gov/41381478/
Press release (in Czech) www.img.cas.cz/2026/01/8901...
Press release (in Czech) www.img.cas.cz/2026/01/8901...
Imbalance of stem-like and effector T cell states in children with early type 1 diabetes across conventional and regulatory subsets - PubMed
Type 1 diabetes (T1D) is an autoimmune disease caused by the loss of self-tolerance toward insulin-producing pancreatic β-cells. Its etiology remains incompletely understood but involves dysregulated T cell responses. Here, we perform single-cell transcriptomic analysis of peripheral blood T cells f …
pubmed.ncbi.nlm.nih.gov
January 9, 2026 at 2:02 PM
Publication pubmed.ncbi.nlm.nih.gov/41381478/
Press release (in Czech) www.img.cas.cz/2026/01/8901...
Press release (in Czech) www.img.cas.cz/2026/01/8901...
🎉Publication in Nature Communications!🎉
The immune system at diagnosis in type 1 diabetes in children isn’t overactive, it’s immature🧒
Veronika Niederlova @vercanie.bsky.social and her colleagues showed that key immune cells fail to fully develop, allowing autoimmunity to arise⚖️
The immune system at diagnosis in type 1 diabetes in children isn’t overactive, it’s immature🧒
Veronika Niederlova @vercanie.bsky.social and her colleagues showed that key immune cells fail to fully develop, allowing autoimmunity to arise⚖️
January 9, 2026 at 2:02 PM
🎉Publication in Nature Communications!🎉
The immune system at diagnosis in type 1 diabetes in children isn’t overactive, it’s immature🧒
Veronika Niederlova @vercanie.bsky.social and her colleagues showed that key immune cells fail to fully develop, allowing autoimmunity to arise⚖️
The immune system at diagnosis in type 1 diabetes in children isn’t overactive, it’s immature🧒
Veronika Niederlova @vercanie.bsky.social and her colleagues showed that key immune cells fail to fully develop, allowing autoimmunity to arise⚖️
Reposted by Institute of Molecular Genetics
Our paper on #tcells in Type 1 #Diabetes is now out in @natcomms.nature.com 👩🔬 rdcu.be/eXEH6
T cells in T1D show higher stem-like signatures and signs of Treg dysfunction. Thanks all the collaborators! @imgprague.bsky.social
T cells in T1D show higher stem-like signatures and signs of Treg dysfunction. Thanks all the collaborators! @imgprague.bsky.social
Imbalance of stem-like and effector T cell states in children with early type 1 diabetes across conventional and regulatory subsets
Nature Communications - Dysregulation of the T cell compartment is a driving factor in the development of Type 1 diabetes (T1D). Here, the authors present a single-cell gene expression analysis of...
rdcu.be
January 5, 2026 at 2:53 PM
Our paper on #tcells in Type 1 #Diabetes is now out in @natcomms.nature.com 👩🔬 rdcu.be/eXEH6
T cells in T1D show higher stem-like signatures and signs of Treg dysfunction. Thanks all the collaborators! @imgprague.bsky.social
T cells in T1D show higher stem-like signatures and signs of Treg dysfunction. Thanks all the collaborators! @imgprague.bsky.social
Read the full story ➡
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Contractile fibroblasts form a transient niche for the branching mammary epithelium - Nature Communications
Fibroblasts represent a heterogenous cell population but how their differences reflect their plasticity and origin is not fully understood. Here, the authors map the origin and fate of a transient con...
www.nature.com
January 6, 2026 at 12:59 PM
Read the full story ➡
www.nature.com/articles/s41...
www.nature.com/articles/s41...
🎉New publication in NatCom!
@sumbalovakoledova.bsky.social and her colleagues identified specialized contractile fibroblasts that actively guide growth and branching of the mammary gland during puberty.
👉These cells are temporary – once their job is done, they transform into other cell types.
@sumbalovakoledova.bsky.social and her colleagues identified specialized contractile fibroblasts that actively guide growth and branching of the mammary gland during puberty.
👉These cells are temporary – once their job is done, they transform into other cell types.
January 6, 2026 at 12:59 PM
🎉New publication in NatCom!
@sumbalovakoledova.bsky.social and her colleagues identified specialized contractile fibroblasts that actively guide growth and branching of the mammary gland during puberty.
👉These cells are temporary – once their job is done, they transform into other cell types.
@sumbalovakoledova.bsky.social and her colleagues identified specialized contractile fibroblasts that actively guide growth and branching of the mammary gland during puberty.
👉These cells are temporary – once their job is done, they transform into other cell types.
PF 2026 🧡💙
December 31, 2025 at 8:22 AM
PF 2026 🧡💙
Merry and scientifically peaceful Christmas!
✨🧬We wish you lovely holidays, minimal cellular stress, stable DNA, functional RNA, well-tempered reactions, and lots of joy not only in the laboratory.
🧡💙Thank you for being with us. And we look forward to another year full of discoveries.
✨🧬We wish you lovely holidays, minimal cellular stress, stable DNA, functional RNA, well-tempered reactions, and lots of joy not only in the laboratory.
🧡💙Thank you for being with us. And we look forward to another year full of discoveries.
December 24, 2025 at 9:58 AM
Merry and scientifically peaceful Christmas!
✨🧬We wish you lovely holidays, minimal cellular stress, stable DNA, functional RNA, well-tempered reactions, and lots of joy not only in the laboratory.
🧡💙Thank you for being with us. And we look forward to another year full of discoveries.
✨🧬We wish you lovely holidays, minimal cellular stress, stable DNA, functional RNA, well-tempered reactions, and lots of joy not only in the laboratory.
🧡💙Thank you for being with us. And we look forward to another year full of discoveries.
Big thanks to Michal Kolář's Laboratory of Genomics and Bioinformatics!
December 16, 2025 at 5:32 PM
Big thanks to Michal Kolář's Laboratory of Genomics and Bioinformatics!
The course brought together PhD students, postdocs, PIs, and technicians, all of whom did an outstanding job.
We’re grateful to be part of their learning journey and look forward to continuing bioinformatic education in the future!
We’re grateful to be part of their learning journey and look forward to continuing bioinformatic education in the future!
December 16, 2025 at 4:46 PM
The course brought together PhD students, postdocs, PIs, and technicians, all of whom did an outstanding job.
We’re grateful to be part of their learning journey and look forward to continuing bioinformatic education in the future!
We’re grateful to be part of their learning journey and look forward to continuing bioinformatic education in the future!
🧬Over three intensive days, participants learned the fundamentals of scRNA-seq data analysis — from quality control and normalization to dimensionality reduction, integration, and functional annotation. Most of the course was hands-on, with group work on participant-selected projects.
December 16, 2025 at 4:46 PM
🧬Over three intensive days, participants learned the fundamentals of scRNA-seq data analysis — from quality control and normalization to dimensionality reduction, integration, and functional annotation. Most of the course was hands-on, with group work on participant-selected projects.
📣We’re proud to announce the successful completion of our first Single-Cell RNA-seq course at the Institute of Molecular Genetics
📅 1–3 December 2025
🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
📅 1–3 December 2025
🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
December 16, 2025 at 4:46 PM
📣We’re proud to announce the successful completion of our first Single-Cell RNA-seq course at the Institute of Molecular Genetics
📅 1–3 December 2025
🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
📅 1–3 December 2025
🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
👩🔬 We’re looking for someone with:
• Tissue culture + basic molecular biology skills
• Curiosity, precision, and motivation
• Ability to work with scientific literature
• Good English communication
🌍 Bonus: Experience with high-throughput data or bioinformatics.
• Tissue culture + basic molecular biology skills
• Curiosity, precision, and motivation
• Ability to work with scientific literature
• Good English communication
🌍 Bonus: Experience with high-throughput data or bioinformatics.
Open PhD positions – Institute of Molecular Genetics of the Czech Academy of Sciences
www.img.cas.cz
December 15, 2025 at 12:05 PM
👩🔬 We’re looking for someone with:
• Tissue culture + basic molecular biology skills
• Curiosity, precision, and motivation
• Ability to work with scientific literature
• Good English communication
🌍 Bonus: Experience with high-throughput data or bioinformatics.
• Tissue culture + basic molecular biology skills
• Curiosity, precision, and motivation
• Ability to work with scientific literature
• Good English communication
🌍 Bonus: Experience with high-throughput data or bioinformatics.