Institute of Molecular Genetics
@imgprague.bsky.social
Public scientific institution, part of the Czech Academy of Sciences. Research in molecular, structure and cell biology, immunology, genomics and bioinformatics.
🎓 PhD Bootcamp:
A weekend full of learning, exploring, and networking!🌟
This traditional event brought together our new PhD students - and for the first time, also the advanced ones🤝
We didn’t forget to spend time outside 🏞️ and enjoy fun evenings together!✨
A weekend full of learning, exploring, and networking!🌟
This traditional event brought together our new PhD students - and for the first time, also the advanced ones🤝
We didn’t forget to spend time outside 🏞️ and enjoy fun evenings together!✨
November 7, 2025 at 1:56 PM
🎓 PhD Bootcamp:
A weekend full of learning, exploring, and networking!🌟
This traditional event brought together our new PhD students - and for the first time, also the advanced ones🤝
We didn’t forget to spend time outside 🏞️ and enjoy fun evenings together!✨
A weekend full of learning, exploring, and networking!🌟
This traditional event brought together our new PhD students - and for the first time, also the advanced ones🤝
We didn’t forget to spend time outside 🏞️ and enjoy fun evenings together!✨
New publication in Nature Communications from Lukáš Čermák lab
⚖️Cells need the right balance between old and new MCM proteins for error-free DNA copying
🧩We identified DCAF12 as a key factor that controls how new MCM complexes are assembled
www.nature.com/articles/s41...
⚖️Cells need the right balance between old and new MCM proteins for error-free DNA copying
🧩We identified DCAF12 as a key factor that controls how new MCM complexes are assembled
www.nature.com/articles/s41...
CRL4DCAF12 regulation of MCMBP ensures optimal licensing of DNA replication - Nature Communications
MCM2-7 complexes drive genome duplication, but their assembly in human cells is not fully understood. Here, the authors identify the CRL4-DCAF12 ubiquitin ligase as crucial for MCM2-7 maturation, safe...
www.nature.com
November 5, 2025 at 11:34 AM
New publication in Nature Communications from Lukáš Čermák lab
⚖️Cells need the right balance between old and new MCM proteins for error-free DNA copying
🧩We identified DCAF12 as a key factor that controls how new MCM complexes are assembled
www.nature.com/articles/s41...
⚖️Cells need the right balance between old and new MCM proteins for error-free DNA copying
🧩We identified DCAF12 as a key factor that controls how new MCM complexes are assembled
www.nature.com/articles/s41...
🧬Get a feeling of electron microscopy in biomedicine in one week
🔬Learn principles of electron microscopy and become an independent user
👩🏫Highly experienced tutors – focus on hands-on training
Register now – spots are limited to 15 participants!
course.img.cas.cz/tem/
🔬Learn principles of electron microscopy and become an independent user
👩🏫Highly experienced tutors – focus on hands-on training
Register now – spots are limited to 15 participants!
course.img.cas.cz/tem/
October 17, 2025 at 6:44 AM
🧬Get a feeling of electron microscopy in biomedicine in one week
🔬Learn principles of electron microscopy and become an independent user
👩🏫Highly experienced tutors – focus on hands-on training
Register now – spots are limited to 15 participants!
course.img.cas.cz/tem/
🔬Learn principles of electron microscopy and become an independent user
👩🏫Highly experienced tutors – focus on hands-on training
Register now – spots are limited to 15 participants!
course.img.cas.cz/tem/
Huge congratulations to Jiří Černý!
📸Nikon Small World - 2025 Photomicrography Competition announced its winners!
www.nikonsmallworld.com
📸Nikon Small World - 2025 Photomicrography Competition announced its winners!
www.nikonsmallworld.com
October 16, 2025 at 3:21 PM
Huge congratulations to Jiří Černý!
📸Nikon Small World - 2025 Photomicrography Competition announced its winners!
www.nikonsmallworld.com
📸Nikon Small World - 2025 Photomicrography Competition announced its winners!
www.nikonsmallworld.com
Reposted by Institute of Molecular Genetics
NIVB unites top research institutes in the Czech Republic accelerating drug and vaccine development against viral and bacterial diseases:
@iocbprague.bsky.social @imgprague.bsky.social @mbuavcr.bsky.social @charlesuni.cuni.cz @masarykuniversity.bsky.social @vschtpraha.bsky.social Biology Centre CAS
@iocbprague.bsky.social @imgprague.bsky.social @mbuavcr.bsky.social @charlesuni.cuni.cz @masarykuniversity.bsky.social @vschtpraha.bsky.social Biology Centre CAS
October 15, 2025 at 11:34 AM
NIVB unites top research institutes in the Czech Republic accelerating drug and vaccine development against viral and bacterial diseases:
@iocbprague.bsky.social @imgprague.bsky.social @mbuavcr.bsky.social @charlesuni.cuni.cz @masarykuniversity.bsky.social @vschtpraha.bsky.social Biology Centre CAS
@iocbprague.bsky.social @imgprague.bsky.social @mbuavcr.bsky.social @charlesuni.cuni.cz @masarykuniversity.bsky.social @vschtpraha.bsky.social Biology Centre CAS
Reposted by Institute of Molecular Genetics
👥 Last month, we hosted Dr. Hana Hanzlikova ( #unibern / @imgprague.bsky.social @czechacademy.bsky.social) for another lecture in the #DanaHockováLecture Series.
#IOCB #IOCBPrague #WomenInScience
#IOCB #IOCBPrague #WomenInScience
October 13, 2025 at 1:53 PM
👥 Last month, we hosted Dr. Hana Hanzlikova ( #unibern / @imgprague.bsky.social @czechacademy.bsky.social) for another lecture in the #DanaHockováLecture Series.
#IOCB #IOCBPrague #WomenInScience
#IOCB #IOCBPrague #WomenInScience
“Scientists’ salaries in the Czech Republic are significantly lower than in Western Europe, which makes it difficult to attract top international talent,” says Meritxell Alberich Jordà, one of the Forbes Top Women Scientists in the Czech Republic
forbes.cz/nejvetsi-brz...
forbes.cz/nejvetsi-brz...
Největší brzda vědy? Kurýr si v Česku vydělá víc než univerzitní profesor
Kvůli nízkým platům ve vědě přichází Česko o řadu talentovaných lidí, kteří odcházejí dělat špičkovou vědu do světa.
forbes.cz
October 10, 2025 at 1:05 PM
“Scientists’ salaries in the Czech Republic are significantly lower than in Western Europe, which makes it difficult to attract top international talent,” says Meritxell Alberich Jordà, one of the Forbes Top Women Scientists in the Czech Republic
forbes.cz/nejvetsi-brz...
forbes.cz/nejvetsi-brz...
Reposted by Institute of Molecular Genetics
Our study on fibroblast functional heterogeneity in mammary glands is out in @natcomms.nature.com! This tour de force by Jakub Sumbal reveals contractile fibroblasts in TEB niche. Great collaboration @imgprague.bsky.social with @frelab.bsky.social @institutcurie.bsky.social
▶️https://rdcu.be/eIIKD
▶️https://rdcu.be/eIIKD
October 5, 2025 at 11:03 PM
Our study on fibroblast functional heterogeneity in mammary glands is out in @natcomms.nature.com! This tour de force by Jakub Sumbal reveals contractile fibroblasts in TEB niche. Great collaboration @imgprague.bsky.social with @frelab.bsky.social @institutcurie.bsky.social
▶️https://rdcu.be/eIIKD
▶️https://rdcu.be/eIIKD
Reposted by Institute of Molecular Genetics
Today is the #BBSGlobalDay — an opportunity to raise awareness of this rare condition and offer support to everyone living with BBS and their loved ones 🌍 🌎 🌏
www.img.cas.cz/2025/10/8758...
www.img.cas.cz/2025/10/8758...
October 4, 2025 at 12:33 PM
Today is the #BBSGlobalDay — an opportunity to raise awareness of this rare condition and offer support to everyone living with BBS and their loved ones 🌍 🌎 🌏
www.img.cas.cz/2025/10/8758...
www.img.cas.cz/2025/10/8758...
Reposted by Institute of Molecular Genetics
From the Czech Academy of Sciences:
Meritxell Alberich Jordà (@imgprague.bsky.social)
Research group: www.img.cas.cz/group/meritx...
#ForbesTopWomenInScience
Meritxell Alberich Jordà (@imgprague.bsky.social)
Research group: www.img.cas.cz/group/meritx...
#ForbesTopWomenInScience
October 3, 2025 at 2:58 PM
From the Czech Academy of Sciences:
Meritxell Alberich Jordà (@imgprague.bsky.social)
Research group: www.img.cas.cz/group/meritx...
#ForbesTopWomenInScience
Meritxell Alberich Jordà (@imgprague.bsky.social)
Research group: www.img.cas.cz/group/meritx...
#ForbesTopWomenInScience
European Researchers' Night last week was a huge success. More than 900 people visited premises of the Krč Biomed Campus.
Thanks to all visitors, organizers and colleagues from @iphys-cas.bsky.social & @mbuavcr.bsky.social
#EuropeanResearchersNight #NocVedcu #NocVedy
Thanks to all visitors, organizers and colleagues from @iphys-cas.bsky.social & @mbuavcr.bsky.social
#EuropeanResearchersNight #NocVedcu #NocVedy
October 3, 2025 at 2:02 PM
European Researchers' Night last week was a huge success. More than 900 people visited premises of the Krč Biomed Campus.
Thanks to all visitors, organizers and colleagues from @iphys-cas.bsky.social & @mbuavcr.bsky.social
#EuropeanResearchersNight #NocVedcu #NocVedy
Thanks to all visitors, organizers and colleagues from @iphys-cas.bsky.social & @mbuavcr.bsky.social
#EuropeanResearchersNight #NocVedcu #NocVedy
✨ For the first time ever, the IMG PhD Conference stepped outside institute grounds! ✨
🏆Best Presentation Awards:
Flash-talk: Magdalena Havlová
Short talk: Irina Ribeiro Bas
Talk: Veronika Niederlová
Poster: Kriti Attri
🏆Best Presentation Awards:
Flash-talk: Magdalena Havlová
Short talk: Irina Ribeiro Bas
Talk: Veronika Niederlová
Poster: Kriti Attri
September 30, 2025 at 2:09 PM
✨ For the first time ever, the IMG PhD Conference stepped outside institute grounds! ✨
🏆Best Presentation Awards:
Flash-talk: Magdalena Havlová
Short talk: Irina Ribeiro Bas
Talk: Veronika Niederlová
Poster: Kriti Attri
🏆Best Presentation Awards:
Flash-talk: Magdalena Havlová
Short talk: Irina Ribeiro Bas
Talk: Veronika Niederlová
Poster: Kriti Attri
Reposted by Institute of Molecular Genetics
#nocvedcu již zítra 26.9. v krčském areálu Akademie věd! Spolupracujeme společně s @mbuavcr.bsky.social
a @imgprague.bsky.social.
Začátek v 17:00. Od 17:30 streamujeme přednášky:
cesnet.zoom.us/j/9714813650...
a @imgprague.bsky.social.
Začátek v 17:00. Od 17:30 streamujeme přednášky:
cesnet.zoom.us/j/9714813650...
September 25, 2025 at 1:35 PM
#nocvedcu již zítra 26.9. v krčském areálu Akademie věd! Spolupracujeme společně s @mbuavcr.bsky.social
a @imgprague.bsky.social.
Začátek v 17:00. Od 17:30 streamujeme přednášky:
cesnet.zoom.us/j/9714813650...
a @imgprague.bsky.social.
Začátek v 17:00. Od 17:30 streamujeme přednášky:
cesnet.zoom.us/j/9714813650...
Reposted by Institute of Molecular Genetics
26th of September: the 20th anniversary of the Researchers’ Night🌜🧪 is coming to the Krč Campus! Four biological institutes - @iphys-cas.bsky.social, @imgprague.bsky.social, @mbuavcr.bsky.social, @iemcas.bsky.social - joined to provide everyone with an unforgettable experience! Come this Friday!
September 24, 2025 at 3:44 PM
26th of September: the 20th anniversary of the Researchers’ Night🌜🧪 is coming to the Krč Campus! Four biological institutes - @iphys-cas.bsky.social, @imgprague.bsky.social, @mbuavcr.bsky.social, @iemcas.bsky.social - joined to provide everyone with an unforgettable experience! Come this Friday!
Reposted by Institute of Molecular Genetics
Huge congrats to our PhD student, Piyush Bisht, for presenting his work on Flipper-TR probe applied to Circulating Tumor Cells at #Czechbioimaging's Imaging Principles of Life 2025 conference in Brno! He had amazing discussions and valuable feedback. Way to go, Piyush!" @imgprague.bsky.social
September 23, 2025 at 2:17 PM
Huge congrats to our PhD student, Piyush Bisht, for presenting his work on Flipper-TR probe applied to Circulating Tumor Cells at #Czechbioimaging's Imaging Principles of Life 2025 conference in Brno! He had amazing discussions and valuable feedback. Way to go, Piyush!" @imgprague.bsky.social
💪 SUPER SCIENTISTS
Forbes magazine has selected our Meritxell (Meri) Alberich Jordà, head of the Laboratory of hematooncology, among the Women Super Scientists in the Czech Republic.
Congratulations! 🎉🙏
#GirlsPower #WomenInScience #ForbesCesko
Forbes magazine has selected our Meritxell (Meri) Alberich Jordà, head of the Laboratory of hematooncology, among the Women Super Scientists in the Czech Republic.
Congratulations! 🎉🙏
#GirlsPower #WomenInScience #ForbesCesko
September 22, 2025 at 1:26 PM
💪 SUPER SCIENTISTS
Forbes magazine has selected our Meritxell (Meri) Alberich Jordà, head of the Laboratory of hematooncology, among the Women Super Scientists in the Czech Republic.
Congratulations! 🎉🙏
#GirlsPower #WomenInScience #ForbesCesko
Forbes magazine has selected our Meritxell (Meri) Alberich Jordà, head of the Laboratory of hematooncology, among the Women Super Scientists in the Czech Republic.
Congratulations! 🎉🙏
#GirlsPower #WomenInScience #ForbesCesko
European Researchers' Night already next Friday at IMG! 🧪🌆
Knowledge free for anyone. Parts of the program in English.
#nocvedcu #nocvedy #EuropeanResearchersNight
Knowledge free for anyone. Parts of the program in English.
#nocvedcu #nocvedy #EuropeanResearchersNight
September 16, 2025 at 1:22 PM
European Researchers' Night already next Friday at IMG! 🧪🌆
Knowledge free for anyone. Parts of the program in English.
#nocvedcu #nocvedy #EuropeanResearchersNight
Knowledge free for anyone. Parts of the program in English.
#nocvedcu #nocvedy #EuropeanResearchersNight
Reposted by Institute of Molecular Genetics
📢We are delighted to share our know-how in light sheet 🔬 of mammary #organoids in this protocol article by Matea Brezak and colleagues. Great 🇨🇿 🇩🇪 collaboration @imgprague.bsky.social Martin Jechlinger Lab at Molit Institut, @embl.org, and Faculty of Medicine MUNI.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
September 1, 2025 at 11:24 PM
📢We are delighted to share our know-how in light sheet 🔬 of mammary #organoids in this protocol article by Matea Brezak and colleagues. Great 🇨🇿 🇩🇪 collaboration @imgprague.bsky.social Martin Jechlinger Lab at Molit Institut, @embl.org, and Faculty of Medicine MUNI.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Institute of Molecular Genetics
“Cellfie: A triple-stained portrait of HeLa’s senescence” by Spoorthi Suresh Hiremath (@imgprague.bsky.social; @gregorlab.bsky.social) has won the Prague @eurobioimaging.bsky.social Node Picture of the Month. Congrats Spoorthi!
August 20, 2025 at 4:02 PM
“Cellfie: A triple-stained portrait of HeLa’s senescence” by Spoorthi Suresh Hiremath (@imgprague.bsky.social; @gregorlab.bsky.social) has won the Prague @eurobioimaging.bsky.social Node Picture of the Month. Congrats Spoorthi!
Reposted by Institute of Molecular Genetics
Argonautes are coming :-) ... soon at @imgprague.bsky.social ... finishing preparations. Still missing a few things like drums, guitar, badges, beer ... but it's under control. I think. I hope. :-))
#argonautes2025
#argonautes2025
August 21, 2025 at 12:48 PM
Argonautes are coming :-) ... soon at @imgprague.bsky.social ... finishing preparations. Still missing a few things like drums, guitar, badges, beer ... but it's under control. I think. I hope. :-))
#argonautes2025
#argonautes2025
🧬 Happy RNA Day! 🎉
A tiny molecule with a massive impact #RNA!
From translating genetic code to fighting diseases through mRNA vaccines, RNA is currently at the heart of innovation in science and medicine.
A tiny molecule with a massive impact #RNA!
From translating genetic code to fighting diseases through mRNA vaccines, RNA is currently at the heart of innovation in science and medicine.
August 1, 2025 at 12:44 PM
🧬 Happy RNA Day! 🎉
A tiny molecule with a massive impact #RNA!
From translating genetic code to fighting diseases through mRNA vaccines, RNA is currently at the heart of innovation in science and medicine.
A tiny molecule with a massive impact #RNA!
From translating genetic code to fighting diseases through mRNA vaccines, RNA is currently at the heart of innovation in science and medicine.
🧬 Happy RNA Day! 🎉
A tiny molecule with a massive impact #RNA!
From translating genetic code to fighting diseases through mRNA vaccines, RNA is currently at the heart of innovation in science and medicine.
A tiny molecule with a massive impact #RNA!
From translating genetic code to fighting diseases through mRNA vaccines, RNA is currently at the heart of innovation in science and medicine.
August 1, 2025 at 12:40 PM
🧬 Happy RNA Day! 🎉
A tiny molecule with a massive impact #RNA!
From translating genetic code to fighting diseases through mRNA vaccines, RNA is currently at the heart of innovation in science and medicine.
A tiny molecule with a massive impact #RNA!
From translating genetic code to fighting diseases through mRNA vaccines, RNA is currently at the heart of innovation in science and medicine.
Reposted by Institute of Molecular Genetics
🗣️ #WomeninScience at IOCB cordially invite you to the next event in the #DanaHockoválecture series by Dr. Hana Hanzlíková ( #UniBern/ @imgprague.bsky.social @czechacademy.bsky.social).
See more ► www.uochb.cz/en/event-cal... ⤵️
See more ► www.uochb.cz/en/event-cal... ⤵️
July 28, 2025 at 10:04 AM
🗣️ #WomeninScience at IOCB cordially invite you to the next event in the #DanaHockoválecture series by Dr. Hana Hanzlíková ( #UniBern/ @imgprague.bsky.social @czechacademy.bsky.social).
See more ► www.uochb.cz/en/event-cal... ⤵️
See more ► www.uochb.cz/en/event-cal... ⤵️
💣Rab25-endosomes influence formation of actin protrusions helping cancer migration
🧲Using magnetogenetics, the position of endosomes in living cells can be manipulated, leading to the triggering of filopodia formation
💉The role of intracellular transport in cancer spread may lead to a new therapy
🧲Using magnetogenetics, the position of endosomes in living cells can be manipulated, leading to the triggering of filopodia formation
💉The role of intracellular transport in cancer spread may lead to a new therapy
"It's official 🎉: Our remote magnetic control of #endosomes, driving invasive protrusions in living cells, has landed in #ScienceAdvances! #Magnetogenetics meets #Rabs! The journey was wild, but it works! 🔥 www.science.org/doi/full/10....
@imgprague.bsky.social #3Dmatrix #CellBiology
@science.org
@imgprague.bsky.social #3Dmatrix #CellBiology
@science.org
Live-cell magnetic manipulation of recycling endosomes reveals their direct effect on actin protrusions to promote invasive migration
Repositioning of Rab25 vesicles containing formin and integrin cargos to the cell periphery promotes protrusion formation.
www.science.org
July 11, 2025 at 11:17 AM
💣Rab25-endosomes influence formation of actin protrusions helping cancer migration
🧲Using magnetogenetics, the position of endosomes in living cells can be manipulated, leading to the triggering of filopodia formation
💉The role of intracellular transport in cancer spread may lead to a new therapy
🧲Using magnetogenetics, the position of endosomes in living cells can be manipulated, leading to the triggering of filopodia formation
💉The role of intracellular transport in cancer spread may lead to a new therapy
Targeted inhibition of the plectin protein can significantly slow the growth of liver tumors and reduce the formation of metastases ⤵
www.irozhlas.cz/zivotni-styl...
@gregorlab.bsky.social @akademievedcr.bsky.social
www.irozhlas.cz/zivotni-styl...
@gregorlab.bsky.social @akademievedcr.bsky.social
Naděje pro léčbu rakoviny jater. Vědci u myší zablokovali protein, který pomáhá v šíření nemoci
Plektin je bílkovina a v rakovinné buňce funguje jako jakési lepidlo, které drží její tvar. Když se poruší, buňka změkne a ztratí svou schopnost pohybu i růstu, nádor tedy hůř roste i metastazuje.
www.irozhlas.cz
July 9, 2025 at 11:29 AM
Targeted inhibition of the plectin protein can significantly slow the growth of liver tumors and reduce the formation of metastases ⤵
www.irozhlas.cz/zivotni-styl...
@gregorlab.bsky.social @akademievedcr.bsky.social
www.irozhlas.cz/zivotni-styl...
@gregorlab.bsky.social @akademievedcr.bsky.social