Institute of Molecular Genetics
@imgprague.bsky.social
Public scientific institution, part of the Czech Academy of Sciences. Research in molecular, structure and cell biology, immunology, genomics and bioinformatics.
Prague became my 2nd home, says Mehak about her PhD transition.
Read the full interview ➡ www.img.cas.cz/2026/02/8964...
Do you wish to join us in one of the safest cities in the world?
🧡APPLY NOW img.cas.cz/phd
Read the full interview ➡ www.img.cas.cz/2026/02/8964...
Do you wish to join us in one of the safest cities in the world?
🧡APPLY NOW img.cas.cz/phd
February 12, 2026 at 1:54 PM
Prague became my 2nd home, says Mehak about her PhD transition.
Read the full interview ➡ www.img.cas.cz/2026/02/8964...
Do you wish to join us in one of the safest cities in the world?
🧡APPLY NOW img.cas.cz/phd
Read the full interview ➡ www.img.cas.cz/2026/02/8964...
Do you wish to join us in one of the safest cities in the world?
🧡APPLY NOW img.cas.cz/phd
🚀Open PhD position!
Combine bioinformatics, single-cell and spatial multi-omics, with machine learning to uncover how the vertebrate head evolved.
🧫Laboratory of Transcriptional Regulation is seeking a highly motivated PhD candidate.
Come and join us
🧡APPLY NOW img.cas.cz/phd
Combine bioinformatics, single-cell and spatial multi-omics, with machine learning to uncover how the vertebrate head evolved.
🧫Laboratory of Transcriptional Regulation is seeking a highly motivated PhD candidate.
Come and join us
🧡APPLY NOW img.cas.cz/phd
February 10, 2026 at 10:52 AM
🚀Open PhD position!
Combine bioinformatics, single-cell and spatial multi-omics, with machine learning to uncover how the vertebrate head evolved.
🧫Laboratory of Transcriptional Regulation is seeking a highly motivated PhD candidate.
Come and join us
🧡APPLY NOW img.cas.cz/phd
Combine bioinformatics, single-cell and spatial multi-omics, with machine learning to uncover how the vertebrate head evolved.
🧫Laboratory of Transcriptional Regulation is seeking a highly motivated PhD candidate.
Come and join us
🧡APPLY NOW img.cas.cz/phd
🚀Open PhD position!
Genome instability promotes cancer development. This project will examine metabolic signaling defects to reveal cell vulnerabilities and novel chemotherapeutics.
🧬Laboratory of Cancer Cell Biology is seeking a new team player.
Do you fit?
🧡APPLY NOW img.cas.cz/phd
Genome instability promotes cancer development. This project will examine metabolic signaling defects to reveal cell vulnerabilities and novel chemotherapeutics.
🧬Laboratory of Cancer Cell Biology is seeking a new team player.
Do you fit?
🧡APPLY NOW img.cas.cz/phd
February 9, 2026 at 9:51 AM
🚀Open PhD position!
Genome instability promotes cancer development. This project will examine metabolic signaling defects to reveal cell vulnerabilities and novel chemotherapeutics.
🧬Laboratory of Cancer Cell Biology is seeking a new team player.
Do you fit?
🧡APPLY NOW img.cas.cz/phd
Genome instability promotes cancer development. This project will examine metabolic signaling defects to reveal cell vulnerabilities and novel chemotherapeutics.
🧬Laboratory of Cancer Cell Biology is seeking a new team player.
Do you fit?
🧡APPLY NOW img.cas.cz/phd
🚀Open PhD position!
Join Nenad at IMG and share with us:
💛Experience
🧡Friendship
💙Professionalism
💜PhD community
APPLY NOW: img.cas.cz/phd
Join Nenad at IMG and share with us:
💛Experience
🧡Friendship
💙Professionalism
💜PhD community
APPLY NOW: img.cas.cz/phd
February 4, 2026 at 1:32 PM
🚀Open PhD position!
Join Nenad at IMG and share with us:
💛Experience
🧡Friendship
💙Professionalism
💜PhD community
APPLY NOW: img.cas.cz/phd
Join Nenad at IMG and share with us:
💛Experience
🧡Friendship
💙Professionalism
💜PhD community
APPLY NOW: img.cas.cz/phd
🚀Open PhD position!
Ever wondered how cells polarize during early development?
This PhD project dives into how mechanochemically-driven cell polarization evolves.
🧪 Genomics
🔬 Biophysics
📊 Fitness analysis
Hooked?
🧡APPLY NOW img.cas.cz/phd
Ever wondered how cells polarize during early development?
This PhD project dives into how mechanochemically-driven cell polarization evolves.
🧪 Genomics
🔬 Biophysics
📊 Fitness analysis
Hooked?
🧡APPLY NOW img.cas.cz/phd
February 3, 2026 at 10:42 AM
🚀Open PhD position!
Ever wondered how cells polarize during early development?
This PhD project dives into how mechanochemically-driven cell polarization evolves.
🧪 Genomics
🔬 Biophysics
📊 Fitness analysis
Hooked?
🧡APPLY NOW img.cas.cz/phd
Ever wondered how cells polarize during early development?
This PhD project dives into how mechanochemically-driven cell polarization evolves.
🧪 Genomics
🔬 Biophysics
📊 Fitness analysis
Hooked?
🧡APPLY NOW img.cas.cz/phd
🚀Open PhD position!
Join our newly established Lab of Immunophysiology.
🧪How do lymph nodes maintain immune tolerance? We‘ll study how fibroblastic reticular cells present self-antigens to support Treg maintenance and prevent autoimmunity.
👉Do you know lab work and coding?
🧡APPLY NOW img.cas.cz/phd
Join our newly established Lab of Immunophysiology.
🧪How do lymph nodes maintain immune tolerance? We‘ll study how fibroblastic reticular cells present self-antigens to support Treg maintenance and prevent autoimmunity.
👉Do you know lab work and coding?
🧡APPLY NOW img.cas.cz/phd
January 29, 2026 at 2:32 PM
🚀Open PhD position!
Join our newly established Lab of Immunophysiology.
🧪How do lymph nodes maintain immune tolerance? We‘ll study how fibroblastic reticular cells present self-antigens to support Treg maintenance and prevent autoimmunity.
👉Do you know lab work and coding?
🧡APPLY NOW img.cas.cz/phd
Join our newly established Lab of Immunophysiology.
🧪How do lymph nodes maintain immune tolerance? We‘ll study how fibroblastic reticular cells present self-antigens to support Treg maintenance and prevent autoimmunity.
👉Do you know lab work and coding?
🧡APPLY NOW img.cas.cz/phd
Joining IMG was the right choice 🎉
Read the full interview with our PhD student Kristína Jamrichová www.img.cas.cz/2025/02/8515...
Be like Kristína, join us now!
APPLY HERE img.cas.cz/phd
Read the full interview with our PhD student Kristína Jamrichová www.img.cas.cz/2025/02/8515...
Be like Kristína, join us now!
APPLY HERE img.cas.cz/phd
January 27, 2026 at 9:59 AM
Joining IMG was the right choice 🎉
Read the full interview with our PhD student Kristína Jamrichová www.img.cas.cz/2025/02/8515...
Be like Kristína, join us now!
APPLY HERE img.cas.cz/phd
Read the full interview with our PhD student Kristína Jamrichová www.img.cas.cz/2025/02/8515...
Be like Kristína, join us now!
APPLY HERE img.cas.cz/phd
🚀Open PhD position!
Lab of Cell and Developmental Biology is seeking a new team player.
🤝Join us to study stem cells, DNA repair, and how 💥cancer💥 really starts.
👉We seek independent thinker ready to learn both experimental and computational approaches.
🧡APPLY NOW img.cas.cz/phd
Lab of Cell and Developmental Biology is seeking a new team player.
🤝Join us to study stem cells, DNA repair, and how 💥cancer💥 really starts.
👉We seek independent thinker ready to learn both experimental and computational approaches.
🧡APPLY NOW img.cas.cz/phd
January 26, 2026 at 12:03 PM
🚀Open PhD position!
Lab of Cell and Developmental Biology is seeking a new team player.
🤝Join us to study stem cells, DNA repair, and how 💥cancer💥 really starts.
👉We seek independent thinker ready to learn both experimental and computational approaches.
🧡APPLY NOW img.cas.cz/phd
Lab of Cell and Developmental Biology is seeking a new team player.
🤝Join us to study stem cells, DNA repair, and how 💥cancer💥 really starts.
👉We seek independent thinker ready to learn both experimental and computational approaches.
🧡APPLY NOW img.cas.cz/phd
Join the Laboratory of Haematooncology and study chronic inflammation, aging and blood stem cells🩸
👩🔬👨🔬We seek a highly motivated, enthusiastic and hard-working PhD student with a strong team spirit
🤝We offer a friendly and supportive environment in a state-of-the-art institution
APPLY: img.cas.cz/phd
👩🔬👨🔬We seek a highly motivated, enthusiastic and hard-working PhD student with a strong team spirit
🤝We offer a friendly and supportive environment in a state-of-the-art institution
APPLY: img.cas.cz/phd
January 22, 2026 at 9:46 AM
Join the Laboratory of Haematooncology and study chronic inflammation, aging and blood stem cells🩸
👩🔬👨🔬We seek a highly motivated, enthusiastic and hard-working PhD student with a strong team spirit
🤝We offer a friendly and supportive environment in a state-of-the-art institution
APPLY: img.cas.cz/phd
👩🔬👨🔬We seek a highly motivated, enthusiastic and hard-working PhD student with a strong team spirit
🤝We offer a friendly and supportive environment in a state-of-the-art institution
APPLY: img.cas.cz/phd
Reposted by Institute of Molecular Genetics
Hope for rare anemia patients: Czech scientists create "perfect" mouse model
Researchers from @czphenogenomics.bsky.social @imgprague.bsky.social achieved a breakthrough in understanding Diamond-Blackfan anemia, a severe genetic disease causing anemia and birth defects in children.
bit.ly/4r4dg6I
Researchers from @czphenogenomics.bsky.social @imgprague.bsky.social achieved a breakthrough in understanding Diamond-Blackfan anemia, a severe genetic disease causing anemia and birth defects in children.
bit.ly/4r4dg6I
Rps19R67∆ mutation creates a model of Diamond–Blackfan anemia and reveals downstream mediators of p53 pathway
Diamond–Blackfan anemia (DBA) is a rare bone marrow failure syndrome accompanied by cardiovascular, skeletal, and urogenital abnormalities. Most of the affected individuals carry mutations in ribosom...
onlinelibrary.wiley.com
January 21, 2026 at 12:51 PM
Hope for rare anemia patients: Czech scientists create "perfect" mouse model
Researchers from @czphenogenomics.bsky.social @imgprague.bsky.social achieved a breakthrough in understanding Diamond-Blackfan anemia, a severe genetic disease causing anemia and birth defects in children.
bit.ly/4r4dg6I
Researchers from @czphenogenomics.bsky.social @imgprague.bsky.social achieved a breakthrough in understanding Diamond-Blackfan anemia, a severe genetic disease causing anemia and birth defects in children.
bit.ly/4r4dg6I
💪PhD at IMG is always a good choice.
Join @sindija.s, our student representative, and start enjoying what IMG offers.
🧡PhD Conference, Career Day, Green Swap and much more - come and see!
Wanna help Sindi organizing PhD events?
APPLY NOW ➡ img.cas.cz/phd
Join @sindija.s, our student representative, and start enjoying what IMG offers.
🧡PhD Conference, Career Day, Green Swap and much more - come and see!
Wanna help Sindi organizing PhD events?
APPLY NOW ➡ img.cas.cz/phd
January 21, 2026 at 9:24 AM
💪PhD at IMG is always a good choice.
Join @sindija.s, our student representative, and start enjoying what IMG offers.
🧡PhD Conference, Career Day, Green Swap and much more - come and see!
Wanna help Sindi organizing PhD events?
APPLY NOW ➡ img.cas.cz/phd
Join @sindija.s, our student representative, and start enjoying what IMG offers.
🧡PhD Conference, Career Day, Green Swap and much more - come and see!
Wanna help Sindi organizing PhD events?
APPLY NOW ➡ img.cas.cz/phd
🚀Open PhD position!
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
January 19, 2026 at 10:16 AM
🚀Open PhD position!
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
🤝Join us in Prague!
Browse our open PhD positions at www.img.cas.cz/phd
Join a global team and supportive environment, work with top-notch facilities, and enjoy our IMG community!
➡APPLY NOW!
Browse our open PhD positions at www.img.cas.cz/phd
Join a global team and supportive environment, work with top-notch facilities, and enjoy our IMG community!
➡APPLY NOW!
January 15, 2026 at 9:13 AM
🤝Join us in Prague!
Browse our open PhD positions at www.img.cas.cz/phd
Join a global team and supportive environment, work with top-notch facilities, and enjoy our IMG community!
➡APPLY NOW!
Browse our open PhD positions at www.img.cas.cz/phd
Join a global team and supportive environment, work with top-notch facilities, and enjoy our IMG community!
➡APPLY NOW!
🚀CALL for PhDs just launched🚀
We are accepting applications for the PhD program
🚨APPLY NOW!🚨
📅28. 2. 2026
➡www.img.cas.cz/phd
We are accepting applications for the PhD program
🚨APPLY NOW!🚨
📅28. 2. 2026
➡www.img.cas.cz/phd
January 13, 2026 at 5:46 PM
🚀CALL for PhDs just launched🚀
We are accepting applications for the PhD program
🚨APPLY NOW!🚨
📅28. 2. 2026
➡www.img.cas.cz/phd
We are accepting applications for the PhD program
🚨APPLY NOW!🚨
📅28. 2. 2026
➡www.img.cas.cz/phd
🎉Publication in Nature Communications!🎉
The immune system at diagnosis in type 1 diabetes in children isn’t overactive, it’s immature🧒
Veronika Niederlova @vercanie.bsky.social and her colleagues showed that key immune cells fail to fully develop, allowing autoimmunity to arise⚖️
The immune system at diagnosis in type 1 diabetes in children isn’t overactive, it’s immature🧒
Veronika Niederlova @vercanie.bsky.social and her colleagues showed that key immune cells fail to fully develop, allowing autoimmunity to arise⚖️
January 9, 2026 at 2:02 PM
🎉Publication in Nature Communications!🎉
The immune system at diagnosis in type 1 diabetes in children isn’t overactive, it’s immature🧒
Veronika Niederlova @vercanie.bsky.social and her colleagues showed that key immune cells fail to fully develop, allowing autoimmunity to arise⚖️
The immune system at diagnosis in type 1 diabetes in children isn’t overactive, it’s immature🧒
Veronika Niederlova @vercanie.bsky.social and her colleagues showed that key immune cells fail to fully develop, allowing autoimmunity to arise⚖️
Reposted by Institute of Molecular Genetics
Our paper on #tcells in Type 1 #Diabetes is now out in @natcomms.nature.com 👩🔬 rdcu.be/eXEH6
T cells in T1D show higher stem-like signatures and signs of Treg dysfunction. Thanks all the collaborators! @imgprague.bsky.social
T cells in T1D show higher stem-like signatures and signs of Treg dysfunction. Thanks all the collaborators! @imgprague.bsky.social
Imbalance of stem-like and effector T cell states in children with early type 1 diabetes across conventional and regulatory subsets
Nature Communications - Dysregulation of the T cell compartment is a driving factor in the development of Type 1 diabetes (T1D). Here, the authors present a single-cell gene expression analysis of...
rdcu.be
January 5, 2026 at 2:53 PM
Our paper on #tcells in Type 1 #Diabetes is now out in @natcomms.nature.com 👩🔬 rdcu.be/eXEH6
T cells in T1D show higher stem-like signatures and signs of Treg dysfunction. Thanks all the collaborators! @imgprague.bsky.social
T cells in T1D show higher stem-like signatures and signs of Treg dysfunction. Thanks all the collaborators! @imgprague.bsky.social
🎉New publication in NatCom!
@sumbalovakoledova.bsky.social and her colleagues identified specialized contractile fibroblasts that actively guide growth and branching of the mammary gland during puberty.
👉These cells are temporary – once their job is done, they transform into other cell types.
@sumbalovakoledova.bsky.social and her colleagues identified specialized contractile fibroblasts that actively guide growth and branching of the mammary gland during puberty.
👉These cells are temporary – once their job is done, they transform into other cell types.
January 6, 2026 at 12:59 PM
🎉New publication in NatCom!
@sumbalovakoledova.bsky.social and her colleagues identified specialized contractile fibroblasts that actively guide growth and branching of the mammary gland during puberty.
👉These cells are temporary – once their job is done, they transform into other cell types.
@sumbalovakoledova.bsky.social and her colleagues identified specialized contractile fibroblasts that actively guide growth and branching of the mammary gland during puberty.
👉These cells are temporary – once their job is done, they transform into other cell types.
PF 2026 🧡💙
December 31, 2025 at 8:22 AM
PF 2026 🧡💙
Merry and scientifically peaceful Christmas!
✨🧬We wish you lovely holidays, minimal cellular stress, stable DNA, functional RNA, well-tempered reactions, and lots of joy not only in the laboratory.
🧡💙Thank you for being with us. And we look forward to another year full of discoveries.
✨🧬We wish you lovely holidays, minimal cellular stress, stable DNA, functional RNA, well-tempered reactions, and lots of joy not only in the laboratory.
🧡💙Thank you for being with us. And we look forward to another year full of discoveries.
December 24, 2025 at 9:58 AM
Merry and scientifically peaceful Christmas!
✨🧬We wish you lovely holidays, minimal cellular stress, stable DNA, functional RNA, well-tempered reactions, and lots of joy not only in the laboratory.
🧡💙Thank you for being with us. And we look forward to another year full of discoveries.
✨🧬We wish you lovely holidays, minimal cellular stress, stable DNA, functional RNA, well-tempered reactions, and lots of joy not only in the laboratory.
🧡💙Thank you for being with us. And we look forward to another year full of discoveries.
📣We’re proud to announce the successful completion of our first Single-Cell RNA-seq course at the Institute of Molecular Genetics
📅 1–3 December 2025
🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
📅 1–3 December 2025
🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
December 16, 2025 at 4:46 PM
📣We’re proud to announce the successful completion of our first Single-Cell RNA-seq course at the Institute of Molecular Genetics
📅 1–3 December 2025
🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
📅 1–3 December 2025
🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
🔥 WE ARE HIRING!
🔬Join Filip Šenigl and dive into the world of somatic hypermutation, DNA repair, and transcriptional kinetics!
Work with cutting-edge methods (CRISPR/Cas9-degron, CUT&RUN, integration libraries) and contribute to high-impact immunology research.
www.img.cas.cz/group/jiri-h...
🔬Join Filip Šenigl and dive into the world of somatic hypermutation, DNA repair, and transcriptional kinetics!
Work with cutting-edge methods (CRISPR/Cas9-degron, CUT&RUN, integration libraries) and contribute to high-impact immunology research.
www.img.cas.cz/group/jiri-h...
December 15, 2025 at 12:05 PM
🔥 WE ARE HIRING!
🔬Join Filip Šenigl and dive into the world of somatic hypermutation, DNA repair, and transcriptional kinetics!
Work with cutting-edge methods (CRISPR/Cas9-degron, CUT&RUN, integration libraries) and contribute to high-impact immunology research.
www.img.cas.cz/group/jiri-h...
🔬Join Filip Šenigl and dive into the world of somatic hypermutation, DNA repair, and transcriptional kinetics!
Work with cutting-edge methods (CRISPR/Cas9-degron, CUT&RUN, integration libraries) and contribute to high-impact immunology research.
www.img.cas.cz/group/jiri-h...
🚨 New publication in Leukemia!
The germline JAK2-R1063H variant drives risk of thrombosis and accelerates leukemic transformation. Our data highlight its impact on stem cell aging and disease progression.
👏Great work by Veronika Zimolová, Lucie Láníková et al
The germline JAK2-R1063H variant drives risk of thrombosis and accelerates leukemic transformation. Our data highlight its impact on stem cell aging and disease progression.
👏Great work by Veronika Zimolová, Lucie Láníková et al
December 12, 2025 at 8:04 AM
🚨 New publication in Leukemia!
The germline JAK2-R1063H variant drives risk of thrombosis and accelerates leukemic transformation. Our data highlight its impact on stem cell aging and disease progression.
👏Great work by Veronika Zimolová, Lucie Láníková et al
The germline JAK2-R1063H variant drives risk of thrombosis and accelerates leukemic transformation. Our data highlight its impact on stem cell aging and disease progression.
👏Great work by Veronika Zimolová, Lucie Láníková et al
Reposted by Institute of Molecular Genetics
Our lab has two new members Hanka and Eashayan #cilia #fun #Xmas #photoshooting @imgprague.bsky.social
December 8, 2025 at 1:39 PM
Our lab has two new members Hanka and Eashayan #cilia #fun #Xmas #photoshooting @imgprague.bsky.social
🚨Welcoming António P. Baptista, who just launched the Laboratory of Immunophysiology at IMG.
His research dives into how immune cells develop and react during infection.
➡Read what he said about his experience, Prague and moving with family: www.img.cas.cz/2025/11/8874...
His research dives into how immune cells develop and react during infection.
➡Read what he said about his experience, Prague and moving with family: www.img.cas.cz/2025/11/8874...
November 25, 2025 at 2:03 PM
🚨Welcoming António P. Baptista, who just launched the Laboratory of Immunophysiology at IMG.
His research dives into how immune cells develop and react during infection.
➡Read what he said about his experience, Prague and moving with family: www.img.cas.cz/2025/11/8874...
His research dives into how immune cells develop and react during infection.
➡Read what he said about his experience, Prague and moving with family: www.img.cas.cz/2025/11/8874...
🎓 PhD Bootcamp:
A weekend full of learning, exploring, and networking!🌟
This traditional event brought together our new PhD students - and for the first time, also the advanced ones🤝
We didn’t forget to spend time outside 🏞️ and enjoy fun evenings together!✨
A weekend full of learning, exploring, and networking!🌟
This traditional event brought together our new PhD students - and for the first time, also the advanced ones🤝
We didn’t forget to spend time outside 🏞️ and enjoy fun evenings together!✨
November 7, 2025 at 1:56 PM
🎓 PhD Bootcamp:
A weekend full of learning, exploring, and networking!🌟
This traditional event brought together our new PhD students - and for the first time, also the advanced ones🤝
We didn’t forget to spend time outside 🏞️ and enjoy fun evenings together!✨
A weekend full of learning, exploring, and networking!🌟
This traditional event brought together our new PhD students - and for the first time, also the advanced ones🤝
We didn’t forget to spend time outside 🏞️ and enjoy fun evenings together!✨