Mark van Raaij
@markvanraaij.bsky.social
Structural biologist, virus proteins, bacteriophages, expresser and purifier, crystallisation, macromolecular crystallography, one of the main editors of Acta Cryst F.
Reposted by Mark van Raaij
November issue out now: journals.iucr.org/f/issues/202...
On the cover: the structure of the kinetically slow and catalytically impaired Gln143Asn mutant of human mitochondrial MnSOD leads to the observation of transient hydrogen peroxide-bound states. More at shorturl.at/41Mb9
On the cover: the structure of the kinetically slow and catalytically impaired Gln143Asn mutant of human mitochondrial MnSOD leads to the observation of transient hydrogen peroxide-bound states. More at shorturl.at/41Mb9
November 5, 2025 at 1:25 PM
November issue out now: journals.iucr.org/f/issues/202...
On the cover: the structure of the kinetically slow and catalytically impaired Gln143Asn mutant of human mitochondrial MnSOD leads to the observation of transient hydrogen peroxide-bound states. More at shorturl.at/41Mb9
On the cover: the structure of the kinetically slow and catalytically impaired Gln143Asn mutant of human mitochondrial MnSOD leads to the observation of transient hydrogen peroxide-bound states. More at shorturl.at/41Mb9
Reposted by Mark van Raaij
40% dierstudies naar hersenbloedingen bevat afbeeldingen die niet kloppen, ontdekten René Aquarius en Kim Wever @radboudumc.bsky.social. Sommige artikelen zijn mogelijk geheel of deels verzonnen. Zorgwekkend, zegt ook @elisabethbik.bsky.social.
Voor @voxweb.bsky.social.
www.voxweb.nl/nieuws/honde...
Voor @voxweb.bsky.social.
www.voxweb.nl/nieuws/honde...
Nijmeegse wetenschappers ontdekken honderden mogelijk frauduleuze publicaties over hersenbloedingen bij dieren - Vox magazine
40 procent van de dierexperimentele studies naar hersenbloedingen bevat afbeeldingen die niet kloppen, ontdekten onderzoekers van het Radboudumc. Een deel van deze publicaties is mogelijk geheel of de...
www.voxweb.nl
October 31, 2025 at 10:11 AM
40% dierstudies naar hersenbloedingen bevat afbeeldingen die niet kloppen, ontdekten René Aquarius en Kim Wever @radboudumc.bsky.social. Sommige artikelen zijn mogelijk geheel of deels verzonnen. Zorgwekkend, zegt ook @elisabethbik.bsky.social.
Voor @voxweb.bsky.social.
www.voxweb.nl/nieuws/honde...
Voor @voxweb.bsky.social.
www.voxweb.nl/nieuws/honde...
Reposted by Mark van Raaij
That merely being “under review” by a Nature family journal is offered as a quality proxy for a paper is a tragic illustration of the extent to which academia is addicted to brands and outsources evaluation
October 25, 2025 at 6:37 PM
That merely being “under review” by a Nature family journal is offered as a quality proxy for a paper is a tragic illustration of the extent to which academia is addicted to brands and outsources evaluation
Reposted by Mark van Raaij
Letter to the editor: Remember the red bus?
Brexiters said EU money would go to the NHS.
Instead, our most deprived communities lost billions in EU investment – and got slogans about “pride” instead.
Brexiters said EU money would go to the NHS.
Instead, our most deprived communities lost billions in EU investment – and got slogans about “pride” instead.
Letter to the editor: £5bn over ten years isn’t ‘ambitious’ – it’s a fraction of what the EU once gave
Letter to the editor
eastangliabylines.co.uk
October 16, 2025 at 6:52 AM
Letter to the editor: Remember the red bus?
Brexiters said EU money would go to the NHS.
Instead, our most deprived communities lost billions in EU investment – and got slogans about “pride” instead.
Brexiters said EU money would go to the NHS.
Instead, our most deprived communities lost billions in EU investment – and got slogans about “pride” instead.
Reposted by Mark van Raaij
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
October 5, 2025 at 9:08 AM
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
Reposted by Mark van Raaij
Douglas H. Juers et al.: Automated gradient equilibration of macromolecular crystals to new solution conditions ##Crystal##Solution##Cracking... ##IUCrhttps://journals.iucr.org/paper?S2053230X25008398
Automated gradient equilibration of macromolecular crystals to new solution conditions
A device and method for gentle, automated and inexpensive solution exchange for macromolecular crystals is described.
journals.iucr.org
October 4, 2025 at 12:00 AM
Douglas H. Juers et al.: Automated gradient equilibration of macromolecular crystals to new solution conditions ##Crystal##Solution##Cracking... ##IUCrhttps://journals.iucr.org/paper?S2053230X25008398
Reposted by Mark van Raaij
WE. NEVER. GIVE. UP. 👊
September 28, 2025 at 5:39 PM
WE. NEVER. GIVE. UP. 👊
Reposted by Mark van Raaij
Happy that I have finally published this work at @epljournal.bsky.social which calculates the distribution of pandemic extinction times using only NPIs (yes lockdowns) & predicts that the covid pandemic could have been eliminated in a time of order months! iopscience.iop.org/article/10.1...
⚛️🧪
⚛️🧪
September 27, 2025 at 10:24 AM
Happy that I have finally published this work at @epljournal.bsky.social which calculates the distribution of pandemic extinction times using only NPIs (yes lockdowns) & predicts that the covid pandemic could have been eliminated in a time of order months! iopscience.iop.org/article/10.1...
⚛️🧪
⚛️🧪
Reposted by Mark van Raaij
I'm incredibly proud to present this @actacrystf.iucr.org interview with Alex Mendez and Cydni Bolling on their first paper ever! The interview was co-led by Dr Graham Chakafana from Hampton University in the USA, who supervised the authors' undergraduate research.
www.youtube.com/watch?v=5rjI...
www.youtube.com/watch?v=5rjI...
Structure of Plasmodium vivax N-myristoyltransferase with the NMT inhibitor IMP-1088
YouTube video by International Union of Crystallography
www.youtube.com
September 24, 2025 at 4:31 PM
I'm incredibly proud to present this @actacrystf.iucr.org interview with Alex Mendez and Cydni Bolling on their first paper ever! The interview was co-led by Dr Graham Chakafana from Hampton University in the USA, who supervised the authors' undergraduate research.
www.youtube.com/watch?v=5rjI...
www.youtube.com/watch?v=5rjI...
Reposted by Mark van Raaij
It was foolish for Russell to approach the hornets’ nest in the first place, but his timing was particularly bad.
August 17, 2025 at 12:09 PM
It was foolish for Russell to approach the hornets’ nest in the first place, but his timing was particularly bad.
Reposted by Mark van Raaij
📣 The #GE3C has awarded the Gold Medal 🎖️, its highest distinction, to Professor Santiago García Granda, from the University of Oviedo and President of the IUCr, in recognition of his extensive and outstanding 🔝 scientific career in the field of crystallography 💎.
September 23, 2025 at 7:51 AM
📣 The #GE3C has awarded the Gold Medal 🎖️, its highest distinction, to Professor Santiago García Granda, from the University of Oviedo and President of the IUCr, in recognition of his extensive and outstanding 🔝 scientific career in the field of crystallography 💎.
Reposted by Mark van Raaij
The crystal structure of Fasciola hepatica TPI has been solved at 1.51 Å and used to perform molecular-docking studies with the most successful fasciolocide triclabendazole #FasciolaHepatica #TriosephosphateIsomerase #TPI doi.org/10.1107/S205...
September 10, 2025 at 2:37 PM
The crystal structure of Fasciola hepatica TPI has been solved at 1.51 Å and used to perform molecular-docking studies with the most successful fasciolocide triclabendazole #FasciolaHepatica #TriosephosphateIsomerase #TPI doi.org/10.1107/S205...
Reposted by Mark van Raaij
Virulence protein J domain 1 maintains the canonical α/β-hydrolase fold but is likely to lack a functional catalytic triad, suggesting functional divergence from classical hydrolases of this superfamily #BacterialPathogens #TypeIVSecretionSystem doi.org/10.1107/S205...
September 9, 2025 at 2:50 PM
Virulence protein J domain 1 maintains the canonical α/β-hydrolase fold but is likely to lack a functional catalytic triad, suggesting functional divergence from classical hydrolases of this superfamily #BacterialPathogens #TypeIVSecretionSystem doi.org/10.1107/S205...
Reposted by Mark van Raaij
Our September issue is available! tinyurl.com/58x22mpx
The cover shows the crystal structure of the N-terminal domain 1 of virulence protein J from Brucella abortus, which adopts an α/β-hydrolase fold but lacks the characteristic catalytic triad: see tinyurl.com/bdduy23d
The cover shows the crystal structure of the N-terminal domain 1 of virulence protein J from Brucella abortus, which adopts an α/β-hydrolase fold but lacks the characteristic catalytic triad: see tinyurl.com/bdduy23d
September 3, 2025 at 2:20 PM
Our September issue is available! tinyurl.com/58x22mpx
The cover shows the crystal structure of the N-terminal domain 1 of virulence protein J from Brucella abortus, which adopts an α/β-hydrolase fold but lacks the characteristic catalytic triad: see tinyurl.com/bdduy23d
The cover shows the crystal structure of the N-terminal domain 1 of virulence protein J from Brucella abortus, which adopts an α/β-hydrolase fold but lacks the characteristic catalytic triad: see tinyurl.com/bdduy23d
Reposted by Mark van Raaij
My quote of the day
Nobody ever thanks you for saving them from the disease they didn't know they were going to get.
William Foege
Nobody ever thanks you for saving them from the disease they didn't know they were going to get.
William Foege
September 1, 2025 at 11:26 AM
My quote of the day
Nobody ever thanks you for saving them from the disease they didn't know they were going to get.
William Foege
Nobody ever thanks you for saving them from the disease they didn't know they were going to get.
William Foege
Reposted by Mark van Raaij
Dear Americans, welcome to the thrilling game of ‘Did this dictator die or just disappear for a day?’ We’ve been playing it with Putin and Lukashenko for decades. Enjoy the suspense.
August 30, 2025 at 11:43 AM
Dear Americans, welcome to the thrilling game of ‘Did this dictator die or just disappear for a day?’ We’ve been playing it with Putin and Lukashenko for decades. Enjoy the suspense.