Marina Lusic
@marinalusic.bsky.social
PI @ CIID, Heidelberg, and @DZIF. Mom of two and scientist in love with nuclear architecture - NPC- RNA processing, metabolic switches in infected immune blood and brain cells 🧬🔬🧬🦠🧫
Reposted by Marina Lusic
I started offering career advice to two junior colleagues today in separate meetings, and both times I caught myself thinking that, if I'm honest, I don't have very good advice on navigating the current funding and job climate. I think it's important to say that no one does.
February 3, 2026 at 3:46 AM
I started offering career advice to two junior colleagues today in separate meetings, and both times I caught myself thinking that, if I'm honest, I don't have very good advice on navigating the current funding and job climate. I think it's important to say that no one does.
Reposted by Marina Lusic
"Another remarkable case is a 106-year-old woman who took up swimming at age 70 & won her first competition three decades later. Longevity runs in the family: she has two younger sisters over 100 & a 110-year-old aunt."
Great story from @marilenharo.bsky.social
www.nature.com/articles/d41... 🧪
Great story from @marilenharo.bsky.social
www.nature.com/articles/d41... 🧪
Still working at 107: supercentenarian study probes genetics of extreme longevity
Scientists seek to understand the factors that have allowed people in Brazil to reach their 100th or even 110th birthdays despite facing adversities.
www.nature.com
January 28, 2026 at 10:51 AM
"Another remarkable case is a 106-year-old woman who took up swimming at age 70 & won her first competition three decades later. Longevity runs in the family: she has two younger sisters over 100 & a 110-year-old aunt."
Great story from @marilenharo.bsky.social
www.nature.com/articles/d41... 🧪
Great story from @marilenharo.bsky.social
www.nature.com/articles/d41... 🧪
Reposted by Marina Lusic
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
January 23, 2026 at 6:41 AM
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
Reposted by Marina Lusic
This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.
www.nature.com/immersive/d4...
www.nature.com/immersive/d4...
January 20, 2026 at 10:53 PM
This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.
www.nature.com/immersive/d4...
www.nature.com/immersive/d4...
Reposted by Marina Lusic
A trial was about to launch for a vaccine that would ward off the HIV virus. It would be an incredible breakthrough. Then it looked as if it would be over before it started. n.pr/3NnYj0O
The near death -- and last-minute reprieve -- of a trial for an HIV vaccine
A trial was about to launch for a vaccine that would ward off the HIV virus. It would be an incredible breakthrough. Then it looked as if it would be over before it started.
n.pr
January 17, 2026 at 5:36 PM
A trial was about to launch for a vaccine that would ward off the HIV virus. It would be an incredible breakthrough. Then it looked as if it would be over before it started. n.pr/3NnYj0O
Reposted by Marina Lusic
1/ 🎄 We got our Christmas present today: "Two distinct chromatin modules regulate proinflammatory gene expression" is now published @natcellbio.nature.com doi.org/10.1038/s415.... Our study introduces a scATAC-seq-based framework for genome-wide analysis of gene regulation features.
December 24, 2025 at 10:44 PM
1/ 🎄 We got our Christmas present today: "Two distinct chromatin modules regulate proinflammatory gene expression" is now published @natcellbio.nature.com doi.org/10.1038/s415.... Our study introduces a scATAC-seq-based framework for genome-wide analysis of gene regulation features.
Exciting times ahead, indeed. Looking forward to 2026 and new inspiring and productive encounters, in Germany and Uk! !!!
Really excited to be awarded a British council UK-Germany Springboard grant!
Exciting times ahead as a UK cohort featuring the labs of myself and Ines Castro and @jollylab.bsky.social will launch trips and research meetings to build a collaboration with @marinalusic.bsky.social in CIID Heidelberg.
Exciting times ahead as a UK cohort featuring the labs of myself and Ines Castro and @jollylab.bsky.social will launch trips and research meetings to build a collaboration with @marinalusic.bsky.social in CIID Heidelberg.
December 21, 2025 at 9:28 PM
Exciting times ahead, indeed. Looking forward to 2026 and new inspiring and productive encounters, in Germany and Uk! !!!
Reposted by Marina Lusic
I just published: ERC-Plus: jackpot science or missed chance to fix academia?
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building.
medium.com/p/erc-plus-j...
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building.
medium.com/p/erc-plus-j...
ERC-Plus: jackpot science or missed chance to fix academia?
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re…
medium.com
December 3, 2025 at 11:42 AM
I just published: ERC-Plus: jackpot science or missed chance to fix academia?
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building.
medium.com/p/erc-plus-j...
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building.
medium.com/p/erc-plus-j...
Reposted by Marina Lusic
Extrusive and cohesive cohesin cooperate to repair double-strand breaks in DNA @science.org @albertomarin.bsky.social @gerlichlab.bsky.social @imbavienna.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
December 5, 2025 at 3:28 AM
Extrusive and cohesive cohesin cooperate to repair double-strand breaks in DNA @science.org @albertomarin.bsky.social @gerlichlab.bsky.social @imbavienna.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Marina Lusic
Here is a copy of last year's Twitter thread explaining our preprint - jump to (21) for the new stuff 👀
Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function
now revised and journal accepted at www.science.org/doi/10.1126/...
🧵👇
Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function
now revised and journal accepted at www.science.org/doi/10.1126/...
🧵👇
November 27, 2025 at 9:59 PM
Here is a copy of last year's Twitter thread explaining our preprint - jump to (21) for the new stuff 👀
Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function
now revised and journal accepted at www.science.org/doi/10.1126/...
🧵👇
Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function
now revised and journal accepted at www.science.org/doi/10.1126/...
🧵👇
Reposted by Marina Lusic
I am happy to share that my postdoctoral work in the @gerlichlab.bsky.social at @imbavienna.bsky.social is finally out 🎉!
Our study reveals how cohesin guides focused and accurate homology search.
Read more 👉 www.science.org/doi/10.1126/...
Follow along for key insights and updates! 🧵
Our study reveals how cohesin guides focused and accurate homology search.
Read more 👉 www.science.org/doi/10.1126/...
Follow along for key insights and updates! 🧵
Cohesin guides homology search during DNA repair using loops and sister chromatid linkages
Accurate repair of DNA double-strand breaks (DSBs) is essential for genome stability, and defective repair underlies diseases such as cancer. Homologous recombination uses an intact homologous sequenc...
www.science.org
December 4, 2025 at 8:18 PM
I am happy to share that my postdoctoral work in the @gerlichlab.bsky.social at @imbavienna.bsky.social is finally out 🎉!
Our study reveals how cohesin guides focused and accurate homology search.
Read more 👉 www.science.org/doi/10.1126/...
Follow along for key insights and updates! 🧵
Our study reveals how cohesin guides focused and accurate homology search.
Read more 👉 www.science.org/doi/10.1126/...
Follow along for key insights and updates! 🧵
Reposted by Marina Lusic
New paper out!
How can we force HIV genomes out of their capsid shells and what can we learn about HIV biology doing so?
Hint: capsid inhibitors actively re-route nuclear HIV complexes, and expose genomes via intriguing structural effects!
open access:
link.springer.com/article/10.1...
read below
How can we force HIV genomes out of their capsid shells and what can we learn about HIV biology doing so?
Hint: capsid inhibitors actively re-route nuclear HIV complexes, and expose genomes via intriguing structural effects!
open access:
link.springer.com/article/10.1...
read below
Lenacapavir-induced capsid damage uncovers HIV-1 genomes emanating from nuclear speckles - The EMBO Journal
Following cell entry, HIV-1 capsids enter the nucleus by passage through nuclear pores and reach nuclear speckles with subsequent uncoating of the reverse-transcribed genome and its integration into s...
link.springer.com
December 4, 2025 at 1:58 PM
New paper out!
How can we force HIV genomes out of their capsid shells and what can we learn about HIV biology doing so?
Hint: capsid inhibitors actively re-route nuclear HIV complexes, and expose genomes via intriguing structural effects!
open access:
link.springer.com/article/10.1...
read below
How can we force HIV genomes out of their capsid shells and what can we learn about HIV biology doing so?
Hint: capsid inhibitors actively re-route nuclear HIV complexes, and expose genomes via intriguing structural effects!
open access:
link.springer.com/article/10.1...
read below
Great new collaboration with @thmllr.bsky.social and Hans-Georg Kräusslich from @ciid-heidelberg.bsky.social came out on December 1st #HIV day - nuclear speckles & HIV capsid & antivirals gallore!!!
If you’re interested in HIV capsids, nuclear speckles, or capsid-targeting antivirals, we’d love for you to check it out and share! 🙌
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Lenacapavir-induced capsid damage uncovers HIV-1 genomes emanating from nuclear speckles - The EMBO Journal
Following cell entry, HIV-1 capsids enter the nucleus by passage through nuclear pores and reach nuclear speckles with subsequent uncoating of the reverse-transcribed genome and its integration into s...
link.springer.com
December 4, 2025 at 5:42 PM
Great new collaboration with @thmllr.bsky.social and Hans-Georg Kräusslich from @ciid-heidelberg.bsky.social came out on December 1st #HIV day - nuclear speckles & HIV capsid & antivirals gallore!!!
Lab life and Christmas cookies can match when the students get creative
December 1, 2025 at 10:14 PM
Lab life and Christmas cookies can match when the students get creative
Reposted by Marina Lusic
Our Spatial Genome Organisation 2025 attendees! Fantastic presentations, discussions & collaborations have taken place over the past 2 days, with plenty more to come. Its been a pleasure working with Karim, Irene & Matthias, looking forward to what the future holds for this brilliant series. #SGO25
November 1, 2025 at 10:32 PM
Our Spatial Genome Organisation 2025 attendees! Fantastic presentations, discussions & collaborations have taken place over the past 2 days, with plenty more to come. Its been a pleasure working with Karim, Irene & Matthias, looking forward to what the future holds for this brilliant series. #SGO25
Reposted by Marina Lusic
🌮✨ Two conferences, one epic poster session - and yes, there’s an open bar! 🍸
We’re mixing research, tacos, and good vibes here in Mexico for #SGO25 & #ecDNA25🇲🇽
We’re mixing research, tacos, and good vibes here in Mexico for #SGO25 & #ecDNA25🇲🇽
November 2, 2025 at 12:39 PM
🌮✨ Two conferences, one epic poster session - and yes, there’s an open bar! 🍸
We’re mixing research, tacos, and good vibes here in Mexico for #SGO25 & #ecDNA25🇲🇽
We’re mixing research, tacos, and good vibes here in Mexico for #SGO25 & #ecDNA25🇲🇽
Reposted by Marina Lusic
@science.org ATP-dependent remodeling of #chromatin #condensates reveals distinct #mesoscale outcomes | Science www.science.org/doi/10.1126/...
October 13, 2025 at 1:50 AM
@science.org ATP-dependent remodeling of #chromatin #condensates reveals distinct #mesoscale outcomes | Science www.science.org/doi/10.1126/...
Reposted by Marina Lusic
Sometimes I think about how from 1935-1975ish, Bell Labs produced an insane amount of revolutionary science and technology, including 11 Nobel Prizes, the transistor, UNIX, C, the laser, the solar cell, information theory, etc. The secret? Provide scientists with ample, steady, no-strings funding.
sites.stat.columbia.edu
October 4, 2025 at 5:35 PM
Sometimes I think about how from 1935-1975ish, Bell Labs produced an insane amount of revolutionary science and technology, including 11 Nobel Prizes, the transistor, UNIX, C, the laser, the solar cell, information theory, etc. The secret? Provide scientists with ample, steady, no-strings funding.
Reposted by Marina Lusic
🚀We’re hiring! Join our international team at @ciid-heidelberg.bsky.social and @uniheidelberg.bsky.social
as a PhD Student or Postdoctoral Researcher to lead cutting edge research projects at the virus-host interface
Postdoc: tinyurl.com/d5sdhbnp
PhD: tinyurl.com/bdz5e5u6
as a PhD Student or Postdoctoral Researcher to lead cutting edge research projects at the virus-host interface
Postdoc: tinyurl.com/d5sdhbnp
PhD: tinyurl.com/bdz5e5u6
October 1, 2025 at 1:38 PM
🚀We’re hiring! Join our international team at @ciid-heidelberg.bsky.social and @uniheidelberg.bsky.social
as a PhD Student or Postdoctoral Researcher to lead cutting edge research projects at the virus-host interface
Postdoc: tinyurl.com/d5sdhbnp
PhD: tinyurl.com/bdz5e5u6
as a PhD Student or Postdoctoral Researcher to lead cutting edge research projects at the virus-host interface
Postdoc: tinyurl.com/d5sdhbnp
PhD: tinyurl.com/bdz5e5u6
Reposted by Marina Lusic
JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
Jane Goodall, legendary primatologist, has died at age 91
Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
n.pr
October 1, 2025 at 6:34 PM
JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
Reposted by Marina Lusic
In 1668, Francesco Redi challenged the idea of spontaneous generation by proving that maggots came from fly eggs, not from rotting meat. His experiment laid the foundation for modern microbiology and disproved centuries of misconceptions about life’s origins. #ScienceHistory
June 7, 2025 at 11:13 AM
In 1668, Francesco Redi challenged the idea of spontaneous generation by proving that maggots came from fly eggs, not from rotting meat. His experiment laid the foundation for modern microbiology and disproved centuries of misconceptions about life’s origins. #ScienceHistory
Reposted by Marina Lusic
Nucleosome phasing by chromatin remodelers regulates macrophage lineage fidelity by preserving nucleosome arrays flanking PU.1-bound sites to prevent lineage-inappropriate transcription by C/EBPβ @cp-immunity.bsky.social www.cell.com/immunity/ful...
September 25, 2025 at 3:25 PM
Nucleosome phasing by chromatin remodelers regulates macrophage lineage fidelity by preserving nucleosome arrays flanking PU.1-bound sites to prevent lineage-inappropriate transcription by C/EBPβ @cp-immunity.bsky.social www.cell.com/immunity/ful...
Reposted by Marina Lusic
about the $100K H1B fee, here's some interesting details: "If an employee is in the U.S., he or she will not be subject if (i) applying to extend or amend H-1B status, or (ii) applying to change from another visa category into H-1B status from within the U.S."
September 20, 2025 at 6:17 PM
about the $100K H1B fee, here's some interesting details: "If an employee is in the U.S., he or she will not be subject if (i) applying to extend or amend H-1B status, or (ii) applying to change from another visa category into H-1B status from within the U.S."
www.nature.com/articles/d41...
Do you think this is a matter of progress or concern?
Do you think this is a matter of progress or concern?
World's first AI-designed viruses a step towards AI-generated life
Scientists used AI to write coherent viral genomes, using them to synthesize bacteriophages capable of killing resistant strains of bacteria.
www.nature.com
September 19, 2025 at 1:55 PM
www.nature.com/articles/d41...
Do you think this is a matter of progress or concern?
Do you think this is a matter of progress or concern?
Reposted by Marina Lusic
1/ One of the questions I get asked about my book is what new they'll discover about #epigenetics.
I hope there will be a lot to learn, but maybe one of the most intriguing stories will be about the contribution of John Pugh.
www.amazon.com/Epigenetics-...
I hope there will be a lot to learn, but maybe one of the most intriguing stories will be about the contribution of John Pugh.
www.amazon.com/Epigenetics-...
Epigenetics: History, Molecules, and Diseases
Buy Epigenetics: History, Molecules, and Diseases on Amazon.com ✓ FREE SHIPPING on qualified orders
www.amazon.com
September 17, 2025 at 11:27 AM
1/ One of the questions I get asked about my book is what new they'll discover about #epigenetics.
I hope there will be a lot to learn, but maybe one of the most intriguing stories will be about the contribution of John Pugh.
www.amazon.com/Epigenetics-...
I hope there will be a lot to learn, but maybe one of the most intriguing stories will be about the contribution of John Pugh.
www.amazon.com/Epigenetics-...