Marina Lusic
@marinalusic.bsky.social
PI @ CIID, Heidelberg, and @DZIF. Mom of two and scientist in love with nuclear architecture - NPC- RNA processing, metabolic switches in infected immune blood and brain cells 🧬🔬🧬🦠🧫
Reposted by Marina Lusic
@science.org ATP-dependent remodeling of #chromatin #condensates reveals distinct #mesoscale outcomes | Science www.science.org/doi/10.1126/...
October 13, 2025 at 1:50 AM
@science.org ATP-dependent remodeling of #chromatin #condensates reveals distinct #mesoscale outcomes | Science www.science.org/doi/10.1126/...
Reposted by Marina Lusic
Sometimes I think about how from 1935-1975ish, Bell Labs produced an insane amount of revolutionary science and technology, including 11 Nobel Prizes, the transistor, UNIX, C, the laser, the solar cell, information theory, etc. The secret? Provide scientists with ample, steady, no-strings funding.
sites.stat.columbia.edu
October 4, 2025 at 5:35 PM
Sometimes I think about how from 1935-1975ish, Bell Labs produced an insane amount of revolutionary science and technology, including 11 Nobel Prizes, the transistor, UNIX, C, the laser, the solar cell, information theory, etc. The secret? Provide scientists with ample, steady, no-strings funding.
Reposted by Marina Lusic
🚀We’re hiring! Join our international team at @ciid-heidelberg.bsky.social and @uniheidelberg.bsky.social
as a PhD Student or Postdoctoral Researcher to lead cutting edge research projects at the virus-host interface
Postdoc: tinyurl.com/d5sdhbnp
PhD: tinyurl.com/bdz5e5u6
as a PhD Student or Postdoctoral Researcher to lead cutting edge research projects at the virus-host interface
Postdoc: tinyurl.com/d5sdhbnp
PhD: tinyurl.com/bdz5e5u6
October 1, 2025 at 1:38 PM
🚀We’re hiring! Join our international team at @ciid-heidelberg.bsky.social and @uniheidelberg.bsky.social
as a PhD Student or Postdoctoral Researcher to lead cutting edge research projects at the virus-host interface
Postdoc: tinyurl.com/d5sdhbnp
PhD: tinyurl.com/bdz5e5u6
as a PhD Student or Postdoctoral Researcher to lead cutting edge research projects at the virus-host interface
Postdoc: tinyurl.com/d5sdhbnp
PhD: tinyurl.com/bdz5e5u6
Reposted by Marina Lusic
JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
Jane Goodall, legendary primatologist, has died at age 91
Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
n.pr
October 1, 2025 at 6:34 PM
JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
Reposted by Marina Lusic
In 1668, Francesco Redi challenged the idea of spontaneous generation by proving that maggots came from fly eggs, not from rotting meat. His experiment laid the foundation for modern microbiology and disproved centuries of misconceptions about life’s origins. #ScienceHistory
June 7, 2025 at 11:13 AM
In 1668, Francesco Redi challenged the idea of spontaneous generation by proving that maggots came from fly eggs, not from rotting meat. His experiment laid the foundation for modern microbiology and disproved centuries of misconceptions about life’s origins. #ScienceHistory
Reposted by Marina Lusic
Nucleosome phasing by chromatin remodelers regulates macrophage lineage fidelity by preserving nucleosome arrays flanking PU.1-bound sites to prevent lineage-inappropriate transcription by C/EBPβ @cp-immunity.bsky.social www.cell.com/immunity/ful...
September 25, 2025 at 3:25 PM
Nucleosome phasing by chromatin remodelers regulates macrophage lineage fidelity by preserving nucleosome arrays flanking PU.1-bound sites to prevent lineage-inappropriate transcription by C/EBPβ @cp-immunity.bsky.social www.cell.com/immunity/ful...
Reposted by Marina Lusic
about the $100K H1B fee, here's some interesting details: "If an employee is in the U.S., he or she will not be subject if (i) applying to extend or amend H-1B status, or (ii) applying to change from another visa category into H-1B status from within the U.S."
September 20, 2025 at 6:17 PM
about the $100K H1B fee, here's some interesting details: "If an employee is in the U.S., he or she will not be subject if (i) applying to extend or amend H-1B status, or (ii) applying to change from another visa category into H-1B status from within the U.S."
www.nature.com/articles/d41...
Do you think this is a matter of progress or concern?
Do you think this is a matter of progress or concern?
World's first AI-designed viruses a step towards AI-generated life
Scientists used AI to write coherent viral genomes, using them to synthesize bacteriophages capable of killing resistant strains of bacteria.
www.nature.com
September 19, 2025 at 1:55 PM
www.nature.com/articles/d41...
Do you think this is a matter of progress or concern?
Do you think this is a matter of progress or concern?
Reposted by Marina Lusic
1/ One of the questions I get asked about my book is what new they'll discover about #epigenetics.
I hope there will be a lot to learn, but maybe one of the most intriguing stories will be about the contribution of John Pugh.
www.amazon.com/Epigenetics-...
I hope there will be a lot to learn, but maybe one of the most intriguing stories will be about the contribution of John Pugh.
www.amazon.com/Epigenetics-...
Epigenetics: History, Molecules, and Diseases
Buy Epigenetics: History, Molecules, and Diseases on Amazon.com ✓ FREE SHIPPING on qualified orders
www.amazon.com
September 17, 2025 at 11:27 AM
1/ One of the questions I get asked about my book is what new they'll discover about #epigenetics.
I hope there will be a lot to learn, but maybe one of the most intriguing stories will be about the contribution of John Pugh.
www.amazon.com/Epigenetics-...
I hope there will be a lot to learn, but maybe one of the most intriguing stories will be about the contribution of John Pugh.
www.amazon.com/Epigenetics-...
Reposted by Marina Lusic
@kazu_maeshima from the Genome Dynamics Laboratory at the National Institute of Genetics (@NIG_idenken) will present groundbreaking research on chromatin organization and behavior in live cells revealed by super-resolution imaging. nyulangone.zoom.us/webinar/regi... #chromatin2025
September 9, 2025 at 5:47 PM
@kazu_maeshima from the Genome Dynamics Laboratory at the National Institute of Genetics (@NIG_idenken) will present groundbreaking research on chromatin organization and behavior in live cells revealed by super-resolution imaging. nyulangone.zoom.us/webinar/regi... #chromatin2025
Reposted by Marina Lusic
Speaker Spotlight: Don’t miss @Anders_S_Hansen from MIT as he unpacks the secrets of distal gene regulation in space and time! Learn how enhancers find and activate their target genes—revealing new insights into the selectivity and dynamics of gene control. Reserve your seat:
September 17, 2025 at 10:59 PM
Speaker Spotlight: Don’t miss @Anders_S_Hansen from MIT as he unpacks the secrets of distal gene regulation in space and time! Learn how enhancers find and activate their target genes—revealing new insights into the selectivity and dynamics of gene control. Reserve your seat:
Reposted by Marina Lusic
“Antiscience has gone beyond U.S. borders to Europe, Australia, and Africa. Defeating it will require unprecedented commitment and international cooperation, not only between scientific organizations, but also their host governments.”
🧪 #Disinformation #AntiScience
time.com/7317436/scie...
🧪 #Disinformation #AntiScience
time.com/7317436/scie...
Antiscience Is an Existential Threat
The ideologically-motivated assault on science threatens us all.
time.com
September 18, 2025 at 2:01 AM
“Antiscience has gone beyond U.S. borders to Europe, Australia, and Africa. Defeating it will require unprecedented commitment and international cooperation, not only between scientific organizations, but also their host governments.”
🧪 #Disinformation #AntiScience
time.com/7317436/scie...
🧪 #Disinformation #AntiScience
time.com/7317436/scie...
Reposted by Marina Lusic
Liquid-liquid phase separation of HP1? Not in our mouse fibroblasts… This paper by the Fabian Erdel group offers a fresh perspective on how this can be reconciled with seemingly conflicting reports: The phase separation propensity of HP1 decreases from yeast → fly → mouse. doi.org/10.1038/s414...
July 11, 2025 at 5:35 AM
Liquid-liquid phase separation of HP1? Not in our mouse fibroblasts… This paper by the Fabian Erdel group offers a fresh perspective on how this can be reconciled with seemingly conflicting reports: The phase separation propensity of HP1 decreases from yeast → fly → mouse. doi.org/10.1038/s414...
Reposted by Marina Lusic
🧬DZIF researchers have discovered that #HIV does not randomly integrate into the genome: the virus follows R-loops as signposts, with the enzyme Aquarius enabling the process. These findings open new avenues for potentially curative treatments.
@marinalusic.bsky.social @natmicrobiol.nature.com
@marinalusic.bsky.social @natmicrobiol.nature.com
How HIV enters the genome – Researchers identify previously unknown mechanism | German Center for Infection Research
Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which
www.dzif.de
September 16, 2025 at 11:32 AM
🧬DZIF researchers have discovered that #HIV does not randomly integrate into the genome: the virus follows R-loops as signposts, with the enzyme Aquarius enabling the process. These findings open new avenues for potentially curative treatments.
@marinalusic.bsky.social @natmicrobiol.nature.com
@marinalusic.bsky.social @natmicrobiol.nature.com
www.dzif.de/en/how-hiv-e...
@dzif.bsky.social @dfg.de @natmicrobiol.nature.com #HIV #HIVScience #HIVCure #Nucleus #Nucleararchitecture #Splicing #R-loops #Genomeorganization
@dzif.bsky.social @dfg.de @natmicrobiol.nature.com #HIV #HIVScience #HIVCure #Nucleus #Nucleararchitecture #Splicing #R-loops #Genomeorganization
How HIV enters the genome – Researchers identify previously unknown mechanism | German Center for Infection Research
Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which
www.dzif.de
September 15, 2025 at 10:37 AM
Reposted by Marina Lusic
Lipid Nanoparticles with Aptamers Enable Targeted mRNA Delivery to CD4⁺ T Cells @biorxivpreprint.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 14, 2025 at 5:12 PM
Lipid Nanoparticles with Aptamers Enable Targeted mRNA Delivery to CD4⁺ T Cells @biorxivpreprint.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
I love his comment on productive careers being unpredictable - and how he was never consciously directing himself anywhere, he was just following his nose
www.science.org/content/arti...
www.science.org/content/arti...
Remembering David Baltimore, a titan who transformed biology and spoke bluntly
The influential Nobel laureate ran institutions, trained future scientific leaders, survived a scandal, and shaped policy
www.science.org
September 10, 2025 at 10:49 AM
I love his comment on productive careers being unpredictable - and how he was never consciously directing himself anywhere, he was just following his nose
www.science.org/content/arti...
www.science.org/content/arti...
Reposted by Marina Lusic
🎵WHY DO ENHANCER!
SUDDENLY APPEAR!
EVERY TIME!
THEY ARE NEAR!?!
JUST LIKE ME!
THEY LONG TO BE!
CLOSE TO POLII! 🎵
www.nature.com/articles/s41...
SUDDENLY APPEAR!
EVERY TIME!
THEY ARE NEAR!?!
JUST LIKE ME!
THEY LONG TO BE!
CLOSE TO POLII! 🎵
www.nature.com/articles/s41...
Distal enhancers loop to proximal enhancers, not to promoters - Nature Reviews Molecular Cell Biology
This Comment posits that enhancers stimulate the transcription machinery only through short-range interactions and, therefore, that enhancer activity at a distance is mediated by chromatin loops betwe...
www.nature.com
September 9, 2025 at 5:42 PM
🎵WHY DO ENHANCER!
SUDDENLY APPEAR!
EVERY TIME!
THEY ARE NEAR!?!
JUST LIKE ME!
THEY LONG TO BE!
CLOSE TO POLII! 🎵
www.nature.com/articles/s41...
SUDDENLY APPEAR!
EVERY TIME!
THEY ARE NEAR!?!
JUST LIKE ME!
THEY LONG TO BE!
CLOSE TO POLII! 🎵
www.nature.com/articles/s41...
Reposted by Marina Lusic
"I think each virus is its own set of surprises."
- David Baltimore. RIP.
- David Baltimore. RIP.
Co-discoverer of reverse transcriptase at 32, Nobel Prize at 37, played a key role at the 1975 Asilomar comference.
David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87
www.nytimes.com
September 8, 2025 at 12:05 AM
"I think each virus is its own set of surprises."
- David Baltimore. RIP.
- David Baltimore. RIP.
Reposted by Marina Lusic
David Baltimore passed away yesterday, “a Nobel Prize-winning biologist whose work…profoundly shaped modern molecular biology &immunology. His discoveries…altered our understanding of viruses &immune responses, laying the foundation for advancements in gene therapy, cancer research, &vaccine devt”🧪🛟
Rest in peace, David Baltimore. explorers.com/david-baltim... @nationalacademies.org
@nobelprize.bsky.social
@nobelprize.bsky.social
New Heroes: David Baltimore
Dr. David Baltimore is a Nobel Prize-winning biologist whose work has profoundly shaped modern molecular biology and immunology. His discoveries have altered our understanding of viruses and immune…
explorers.com
September 8, 2025 at 1:56 AM
David Baltimore passed away yesterday, “a Nobel Prize-winning biologist whose work…profoundly shaped modern molecular biology &immunology. His discoveries…altered our understanding of viruses &immune responses, laying the foundation for advancements in gene therapy, cancer research, &vaccine devt”🧪🛟
David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87
www.nytimes.com
September 7, 2025 at 8:24 PM
Reposted by Marina Lusic
Researchers implanted CRISPR-edited pancreas cells into a person with type-1 diabetes.
The cells produced insulin for months
There was no need for immune-dampening drugs, due to gene edits that allowed the cells to evade detection by the recipient’s immune system.
🧪
www.nature.com/articles/d41...
The cells produced insulin for months
There was no need for immune-dampening drugs, due to gene edits that allowed the cells to evade detection by the recipient’s immune system.
🧪
www.nature.com/articles/d41...
Hope for diabetes: CRISPR-edited cells pump out insulin in a person – and evade immune detection
Edits create cells that don’t trigger an immune response, allowing implant recipient to forego immune-suppressing drugs.
www.nature.com
September 7, 2025 at 5:57 AM
Researchers implanted CRISPR-edited pancreas cells into a person with type-1 diabetes.
The cells produced insulin for months
There was no need for immune-dampening drugs, due to gene edits that allowed the cells to evade detection by the recipient’s immune system.
🧪
www.nature.com/articles/d41...
The cells produced insulin for months
There was no need for immune-dampening drugs, due to gene edits that allowed the cells to evade detection by the recipient’s immune system.
🧪
www.nature.com/articles/d41...
Reposted by Marina Lusic
Out now!
🍫🦠A defined microbial community reproduces attributes of fine flavour #chocolate fermentation
By Gabriel Castrillo, David Salt & co
#microsky #microbiomesky 🧪
Read it here: www.nature.com/articles/s41...
🍫🦠A defined microbial community reproduces attributes of fine flavour #chocolate fermentation
By Gabriel Castrillo, David Salt & co
#microsky #microbiomesky 🧪
Read it here: www.nature.com/articles/s41...
A defined microbial community reproduces attributes of fine flavour chocolate fermentation - Nature Microbiology
An in-depth microbiological and metagenomic analysis of Colombian farm and fermentation facilities resulted in the design of a defined microbial community that can reproduce the flavour of fine chocol...
www.nature.com
August 18, 2025 at 3:35 PM
Out now!
🍫🦠A defined microbial community reproduces attributes of fine flavour #chocolate fermentation
By Gabriel Castrillo, David Salt & co
#microsky #microbiomesky 🧪
Read it here: www.nature.com/articles/s41...
🍫🦠A defined microbial community reproduces attributes of fine flavour #chocolate fermentation
By Gabriel Castrillo, David Salt & co
#microsky #microbiomesky 🧪
Read it here: www.nature.com/articles/s41...
Reposted by Marina Lusic
Mind-blowing. "To our knowledge, females needing to clone members of another species have not previously been observed"
How is this possible?
This ant can lay eggs of two different species, birthed by the same mother
This ant can lay eggs of two different species, birthed by the same mother
September 4, 2025 at 12:38 PM
Mind-blowing. "To our knowledge, females needing to clone members of another species have not previously been observed"