Maria Viola
@mariafviola.bsky.social
Wanderer and macrophage enthusiast, working in Bonn @masslab !
Had the wonderful opportunity to present our data on the effect of microplastics on macrophages at #EMDS2025 ! Such a beautiful venue 🤩 @masslab.bsky.social
Fascinating (and disturbing!) presentation about the impact of ingested microplastics on liver macrophages by @mariafviola.bsky.social #EMDS2025
September 16, 2025 at 1:07 PM
Had the wonderful opportunity to present our data on the effect of microplastics on macrophages at #EMDS2025 ! Such a beautiful venue 🤩 @masslab.bsky.social
Reposted by Maria Viola
🔥NEW paper from our lab! Ever wondered how the metabolite/lipid composition of human bone marrow HSCs changes during differentiation,aging,AML? Check our work www.nature.com/articles/s41... driven by the brilliant Marialena & Maricarmen with Jörg! @mpi-ie.bsky.social @ethz.ch @natcellbio.nature.com
Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells - Nature Cell Biology
Lalioti, Romero-Mulero et al. combine metabolomics, lipidomics and transcriptomics of haematopoietic stem and progenitor cells during differentiation, ageing and leukaemia, finding a role for choline ...
www.nature.com
July 16, 2025 at 10:13 AM
🔥NEW paper from our lab! Ever wondered how the metabolite/lipid composition of human bone marrow HSCs changes during differentiation,aging,AML? Check our work www.nature.com/articles/s41... driven by the brilliant Marialena & Maricarmen with Jörg! @mpi-ie.bsky.social @ethz.ch @natcellbio.nature.com
Reposted by Maria Viola
Nature research paper: Kupffer cell programming by maternal obesity triggers fatty liver disease
https://go.nature.com/4laOA9s
https://go.nature.com/4laOA9s
Kupffer cell programming by maternal obesity triggers fatty liver disease - Nature
In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.
go.nature.com
June 19, 2025 at 9:48 AM
Nature research paper: Kupffer cell programming by maternal obesity triggers fatty liver disease
https://go.nature.com/4laOA9s
https://go.nature.com/4laOA9s
It‘s finally out!!! ⬇️
We are SO EXCITED to share our story @nature.com:
🧵1/
Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b
🧵1/
Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b
Kupffer cell programming by maternal obesity triggers fatty liver disease
Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.
rdcu.be
June 18, 2025 at 5:00 PM
It‘s finally out!!! ⬇️
Reposted by Maria Viola
Just presented our story on #KupfferCells #liver & #microplastics togehter with @mariafviola.bsky.social in the basic science session @ #EASL2025 in #Amsterdam. Great format to promote ECRs and for fantastic discussions with scientists and clinicians!
May 7, 2025 at 10:09 AM
Just presented our story on #KupfferCells #liver & #microplastics togehter with @mariafviola.bsky.social in the basic science session @ #EASL2025 in #Amsterdam. Great format to promote ECRs and for fantastic discussions with scientists and clinicians!
Reposted by Maria Viola
Read our newest publication @jem.org about #microglia and #CD8Tcell interactions in spastic paraplegia! 💡Immune activation happens before #neuronal loss! 💡
Team effort with the labs of Marc Beyer and Ralf Stumm 👇
doi.org/10.1084/jem....
@limes-bonn.bsky.social @immunosens.bsky.social #immunosky
Team effort with the labs of Marc Beyer and Ralf Stumm 👇
doi.org/10.1084/jem....
@limes-bonn.bsky.social @immunosens.bsky.social #immunosky
April 23, 2025 at 2:45 PM
Read our newest publication @jem.org about #microglia and #CD8Tcell interactions in spastic paraplegia! 💡Immune activation happens before #neuronal loss! 💡
Team effort with the labs of Marc Beyer and Ralf Stumm 👇
doi.org/10.1084/jem....
@limes-bonn.bsky.social @immunosens.bsky.social #immunosky
Team effort with the labs of Marc Beyer and Ralf Stumm 👇
doi.org/10.1084/jem....
@limes-bonn.bsky.social @immunosens.bsky.social #immunosky
Please check out this awesome tldr of our new preprint on micro- and nanoplastics and their effect on #macrophages and #metabolism ! So excited to share this with the world, let us know what you think ! #microplastics #nanoplastics
1/ 🚨 New preprint alert! 🚨
Micro- and nanoplastics (MNPs) are everywhere, but what happens when they get inside us? Our latest study reveals how chronic plastic exposure affects macrophages and metabolism in a size-dependent manner. 🧵👇 www.researchsquare.com/article/rs-6...
Micro- and nanoplastics (MNPs) are everywhere, but what happens when they get inside us? Our latest study reveals how chronic plastic exposure affects macrophages and metabolism in a size-dependent manner. 🧵👇 www.researchsquare.com/article/rs-6...
Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism
Plastic pollution is an emerging yet understudied environmental risk to the immune system. Once ingested, nano- and microplastic particles (MNPs) can translocate from the gut to internal organs, with ...
www.researchsquare.com
March 18, 2025 at 9:14 PM
Please check out this awesome tldr of our new preprint on micro- and nanoplastics and their effect on #macrophages and #metabolism ! So excited to share this with the world, let us know what you think ! #microplastics #nanoplastics
So happy this is *finally* out!
Our new paper is also out in Gut! gut.bmj.com/content/earl...
#Mastcells #IBS #GISky #Immunosky #MRGPRX2 #pain
#Mastcells #IBS #GISky #Immunosky #MRGPRX2 #pain
Characterisation of MRGPRX2+ mast cells in irritable bowel syndrome
Background Mast cell activation is an important driver of abdominal pain in irritable bowel syndrome (IBS). While evidence supports the role of IgE-mediated mast cell activation in visceral pain devel...
gut.bmj.com
February 26, 2025 at 6:44 AM
So happy this is *finally* out!
Could bacterial translocation during colitis rewire the bone marrow? Check out our highlight of these cool findings by the Sancho lab ⬇️ authors.elsevier.com/a/1kbBf3qNrU...
@masslab.bsky.social
@masslab.bsky.social
February 11, 2025 at 8:15 PM
Could bacterial translocation during colitis rewire the bone marrow? Check out our highlight of these cool findings by the Sancho lab ⬇️ authors.elsevier.com/a/1kbBf3qNrU...
@masslab.bsky.social
@masslab.bsky.social
Reposted by Maria Viola
"Bacterial translocation promotes #trained #immunity" !!! 🤩
Check out our preview highlighting the beautiful peace @cp-immunity.bsky.social by the Sanches lab. With @mariafviola.bsky.social
#macrophages #Mincle authors.elsevier.com/a/1kbBf3qNrU...
Check out our preview highlighting the beautiful peace @cp-immunity.bsky.social by the Sanches lab. With @mariafviola.bsky.social
#macrophages #Mincle authors.elsevier.com/a/1kbBf3qNrU...
February 11, 2025 at 5:16 PM
"Bacterial translocation promotes #trained #immunity" !!! 🤩
Check out our preview highlighting the beautiful peace @cp-immunity.bsky.social by the Sanches lab. With @mariafviola.bsky.social
#macrophages #Mincle authors.elsevier.com/a/1kbBf3qNrU...
Check out our preview highlighting the beautiful peace @cp-immunity.bsky.social by the Sanches lab. With @mariafviola.bsky.social
#macrophages #Mincle authors.elsevier.com/a/1kbBf3qNrU...
Reposted by Maria Viola
Join our #MagNet #Seminar by Nicolas Venteclef! He will be talking about #epigenetics and #adipose tissue #macrophages: January 20th at 4pm CET. Enter #zoom via QR code
January 15, 2025 at 3:33 PM
Join our #MagNet #Seminar by Nicolas Venteclef! He will be talking about #epigenetics and #adipose tissue #macrophages: January 20th at 4pm CET. Enter #zoom via QR code
Reposted by Maria Viola
Are you looking for a #PhD position in the interdisciplinary field of #immunology #development #cellbiology? Do you love #macrophages? #FOR5775 is hiring!! Find details here: macrophagenetwork.com/news-2/
Pls repost👇 #immunosky
Pls repost👇 #immunosky
News – My WordPress
macrophagenetwork.com
December 21, 2024 at 3:02 PM
Are you looking for a #PhD position in the interdisciplinary field of #immunology #development #cellbiology? Do you love #macrophages? #FOR5775 is hiring!! Find details here: macrophagenetwork.com/news-2/
Pls repost👇 #immunosky
Pls repost👇 #immunosky
Reposted by Maria Viola
We are super happy that our #FOR5775 #MagNet got funded! 🥳 Thanks to @dfgpublic.bsky.social look out for interesting #macrophage science in the coming 4 years!
www.dfg.de/de/service/p...
www.dfg.de/de/service/p...
DFG fördert acht neue Forschungsgruppen
www.dfg.de
December 12, 2024 at 9:29 AM
We are super happy that our #FOR5775 #MagNet got funded! 🥳 Thanks to @dfgpublic.bsky.social look out for interesting #macrophage science in the coming 4 years!
www.dfg.de/de/service/p...
www.dfg.de/de/service/p...
Not ✨macrophages✨ but a characterisation of a rather elusive cell type in the human colon : mast cells! Congrats @hindhussein.bsky.social , I've been looking forward to this !
Intro time! I'm Hind, a mucosal #immunologist working in KU Leuven on mast cells in health and in gut disease.
Speaking of, I can finally show what I have been working on for the last 4 years, ie characterizing human mast cells in layers of the colon via scRNAseq
www.biorxiv.org/content/10.1...
Speaking of, I can finally show what I have been working on for the last 4 years, ie characterizing human mast cells in layers of the colon via scRNAseq
www.biorxiv.org/content/10.1...
Single cell transcriptomics reveal mast cell heterogeneity in the human gut
Gut mast cells are key players in infection and inflammation, as well as in homeostasis. Mast cells regulate gastrointestinal (GI) function by controlling vascular and epithelial permeability, and int...
www.biorxiv.org
December 4, 2024 at 9:53 AM
Not ✨macrophages✨ but a characterisation of a rather elusive cell type in the human colon : mast cells! Congrats @hindhussein.bsky.social , I've been looking forward to this !
@masslab.bsky.social had a successful #EMDS2024!
2 #poster #prizes for the incredible @mariafviola.bsky.social and @haohuang0086.bsky.social at #EMDS 🫶 #macrophages rock! #immunosky
November 29, 2024 at 11:59 AM
@masslab.bsky.social had a successful #EMDS2024!
OMG #EMDS2024 what is this room 😍 @haohuang0086.bsky.social
November 27, 2024 at 7:34 AM
OMG #EMDS2024 what is this room 😍 @haohuang0086.bsky.social
Reposted by Maria Viola
1/ Keen to share the story of my postdoc research out in @natureportfolio.bsky.social! We built a massive resource characterizing the spatial landscape of the gut—and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
www.nature.com
November 21, 2024 at 10:21 PM
1/ Keen to share the story of my postdoc research out in @natureportfolio.bsky.social! We built a massive resource characterizing the spatial landscape of the gut—and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
@masslab.bsky.social is on 🦋 ! Follow for lots of macrophage content 🤓
November 22, 2024 at 11:36 AM
@masslab.bsky.social is on 🦋 ! Follow for lots of macrophage content 🤓
Reposted by Maria Viola
My first #FluorescenceFriday post on BlueSky 😱.🤞 that this platform makes for a great space to share science.
#bioart #sciart #pathart #histoart #microscopy #intestine
#bioart #sciart #pathart #histoart #microscopy #intestine
November 16, 2024 at 4:35 AM
My first #FluorescenceFriday post on BlueSky 😱.🤞 that this platform makes for a great space to share science.
#bioart #sciart #pathart #histoart #microscopy #intestine
#bioart #sciart #pathart #histoart #microscopy #intestine
Macrophage people, who’s going to be at #EMDS2024? I will be presenting a poster on our latest work on what all these microplastics are doing to our liver (spoiler alert: it’s BAD) and I’d love to connect to other people interested in #macrophages #gutimmunology
November 16, 2024 at 8:57 AM
Macrophage people, who’s going to be at #EMDS2024? I will be presenting a poster on our latest work on what all these microplastics are doing to our liver (spoiler alert: it’s BAD) and I’d love to connect to other people interested in #macrophages #gutimmunology
So cool!
7 years ago, I met a junior fellow named Jason Buenrostro who blew me away with a vision of futuristic genomic technologies
Today, we (Ajay Labade, Caroline Comenho) are excited to share our first steps into that future: Expansion in situ genome sequencing
1/
Today, we (Ajay Labade, Caroline Comenho) are excited to share our first steps into that future: Expansion in situ genome sequencing
1/
November 14, 2024 at 7:53 PM
So cool!
As my blatant tour of self-promotion continues.. macrophages are so much more than just cells that eat things! Yet, even the eating can be very cool. Here, we showed that macrophages in gut shape the nervous system, and this makes 💩 happen correctly in adulthood: www.nature.com/articles/s41...
Dedicated macrophages organize and maintain the enteric nervous system - Nature
Resident macrophages of the muscularis externa refine the enteric nervous system (ENS) early in life by pruning synapses and phagocytosing enteric neurons, and later switch to a neuro-supportive funct...
www.nature.com
November 13, 2024 at 5:19 PM
As my blatant tour of self-promotion continues.. macrophages are so much more than just cells that eat things! Yet, even the eating can be very cool. Here, we showed that macrophages in gut shape the nervous system, and this makes 💩 happen correctly in adulthood: www.nature.com/articles/s41...
First up: our recent brainstorm on something a little different. We know macrophages are influenced by their surroundings, but do they retain memory of early life? Cool paper to follow, but for now: www.frontiersin.org/journals/imm...
Frontiers | Developmental programming of tissue-resident macrophages
www.frontiersin.org
November 13, 2024 at 5:04 PM
First up: our recent brainstorm on something a little different. We know macrophages are influenced by their surroundings, but do they retain memory of early life? Cool paper to follow, but for now: www.frontiersin.org/journals/imm...
Hi! I joined the migration and am new here. I work on macrophages and am interested in all things science! Please help me fill my feed with papers and interesting discussions #AcademicSky #Immunology #science #macrophages
November 13, 2024 at 4:56 PM
Hi! I joined the migration and am new here. I work on macrophages and am interested in all things science! Please help me fill my feed with papers and interesting discussions #AcademicSky #Immunology #science #macrophages