Madalena M. Reimão Pinto
@madalenamrp.bsky.social
Incoming Group Leader @ MPI-CBG
Postdoc @ Schier lab
PhD @ Ameres lab
Fascinated about post-transcriptional gene regulation & RNA biology in early development.
Postdoc @ Schier lab
PhD @ Ameres lab
Fascinated about post-transcriptional gene regulation & RNA biology in early development.
This past month marked the end of an era at the @schierlab.bsky.social @biozentrum.unibas.ch. It was a meaningful, intense, often challenging, but also incredibly rewarding chapter of my scientific journey. Thank you all in the Schier Lab for the unconditional support and the Schierleading!
December 2, 2025 at 1:47 PM
This past month marked the end of an era at the @schierlab.bsky.social @biozentrum.unibas.ch. It was a meaningful, intense, often challenging, but also incredibly rewarding chapter of my scientific journey. Thank you all in the Schier Lab for the unconditional support and the Schierleading!
A dire warning about what is happening in the U.S. thenode.biologists.com/hungary-offe...
Hungary offers a dire warning about what is happening in the U.S. - the Node
I work at Northwestern University where all of our NIH funding has been frozen since March. I am increasingly concerned that too few of my fellow
thenode.biologists.com
September 23, 2025 at 10:45 AM
A dire warning about what is happening in the U.S. thenode.biologists.com/hungary-offe...
Reposted by Madalena M. Reimão Pinto
I am excited to share that I will join the Friedrich Miescher Institute @fmiscience.bsky.social in Basel as a group leader, starting my lab in March 2026 🎉
We will explore cell fate regulation during organogenesis, with a focus on how cell elimination underlies the emergence of functional tissues.
We will explore cell fate regulation during organogenesis, with a focus on how cell elimination underlies the emergence of functional tissues.
August 25, 2025 at 5:21 PM
I am excited to share that I will join the Friedrich Miescher Institute @fmiscience.bsky.social in Basel as a group leader, starting my lab in March 2026 🎉
We will explore cell fate regulation during organogenesis, with a focus on how cell elimination underlies the emergence of functional tissues.
We will explore cell fate regulation during organogenesis, with a focus on how cell elimination underlies the emergence of functional tissues.
Reposted by Madalena M. Reimão Pinto
Excited to share our latest work, led by the incredible @automnenine.bsky.social (now an Ass. Prof. at Princeton)! We uncover key insights into the retrotransposition mechanisms of LINE-1 ORF2p, the enzyme responsible for writing a significant portion of our genome.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Structural mechanism of LINE-1 target-primed reverse transcription
Long interspersed element-1 (LINE-1) retrotransposons are the only active autonomous transposable elements in humans. They propagate by reverse transcribing their mRNA into new genomic locations by a ...
www.science.org
March 6, 2025 at 9:33 PM
Excited to share our latest work, led by the incredible @automnenine.bsky.social (now an Ass. Prof. at Princeton)! We uncover key insights into the retrotransposition mechanisms of LINE-1 ORF2p, the enzyme responsible for writing a significant portion of our genome.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Madalena M. Reimão Pinto
Applications open: Masters in Cancer Biology in Heidelberg. 100% English, international program focusing on hands-on research from discovery to translation in a top European science hub. Apply now:
www.dkfz.de/en/career/ca...
www.dkfz.de/en/career/ca...
Major Cancer Biology (MSc) - German Cancer Research CenterLogo des Deutschen KrebsforschungszentrumsLogo des Deutschen KrebsforschungszentrumLogo der Deutschen Zentren der GesundheitsforschungLogo des...
www.dkfz.de
March 3, 2025 at 1:20 PM
Applications open: Masters in Cancer Biology in Heidelberg. 100% English, international program focusing on hands-on research from discovery to translation in a top European science hub. Apply now:
www.dkfz.de/en/career/ca...
www.dkfz.de/en/career/ca...
Reposted by Madalena M. Reimão Pinto
Using a newly developed AI model, the research group @schierlab.bsky.social @biozentrum.unibas.ch @unibasel.ch has discovered in #zebrafish that certain sections of #mRNA control the extent of protein synthesis during early embryonic development. ow.ly/4zyU50V7v1c @cellpress.bsky.social
February 27, 2025 at 11:39 AM
Using a newly developed AI model, the research group @schierlab.bsky.social @biozentrum.unibas.ch @unibasel.ch has discovered in #zebrafish that certain sections of #mRNA control the extent of protein synthesis during early embryonic development. ow.ly/4zyU50V7v1c @cellpress.bsky.social
Reposted by Madalena M. Reimão Pinto
📢 Don't miss! Matthias Muhar of ETH Zurich Corn Lab will speak at our #DahlemColloquium!
📜 How chemical scars mark proteins for degradation
📆 05. MAR, 11:00 AM (CET)
📍 MPIMG, Berlin
🔗 www.molgen.mpg.de/events/41002...
📜 How chemical scars mark proteins for degradation
📆 05. MAR, 11:00 AM (CET)
📍 MPIMG, Berlin
🔗 www.molgen.mpg.de/events/41002...
February 27, 2025 at 1:20 PM
📢 Don't miss! Matthias Muhar of ETH Zurich Corn Lab will speak at our #DahlemColloquium!
📜 How chemical scars mark proteins for degradation
📆 05. MAR, 11:00 AM (CET)
📍 MPIMG, Berlin
🔗 www.molgen.mpg.de/events/41002...
📜 How chemical scars mark proteins for degradation
📆 05. MAR, 11:00 AM (CET)
📍 MPIMG, Berlin
🔗 www.molgen.mpg.de/events/41002...
Reposted by Madalena M. Reimão Pinto
Translation of mRNA can be triggered with spatiotemporal control in zebrafish 🐟 embryos by light ⚡ & FlashCaps 🧪⚗😊 Kudos to all authors and collaborators 🙏👍
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Spatiotemporal control of translation in live zebrafish embryos via photoprotected mRNAs - Communications Chemistry
Translation of mRNA into protein is a fundamental process and tightly controlled during development, however, experimentally controlling the mRNA translation remains challenging. Here, the authors dem...
www.nature.com
January 27, 2025 at 8:21 PM
Translation of mRNA can be triggered with spatiotemporal control in zebrafish 🐟 embryos by light ⚡ & FlashCaps 🧪⚗😊 Kudos to all authors and collaborators 🙏👍
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Madalena M. Reimão Pinto
Our new preprint is out - please share!
We asked: How can we make CRISPR knockouts in vivo more efficient? And set up an assay that enables detection of CRISPR cutting with 100s-1000s of sgRNAs over entire chromosome arms in living animals.
Grab a ☕ and let’s dive in. 🧵🧪 1/n
#CRISPR #geneediting
We asked: How can we make CRISPR knockouts in vivo more efficient? And set up an assay that enables detection of CRISPR cutting with 100s-1000s of sgRNAs over entire chromosome arms in living animals.
Grab a ☕ and let’s dive in. 🧵🧪 1/n
#CRISPR #geneediting
December 2, 2024 at 3:16 PM
Our new preprint is out - please share!
We asked: How can we make CRISPR knockouts in vivo more efficient? And set up an assay that enables detection of CRISPR cutting with 100s-1000s of sgRNAs over entire chromosome arms in living animals.
Grab a ☕ and let’s dive in. 🧵🧪 1/n
#CRISPR #geneediting
We asked: How can we make CRISPR knockouts in vivo more efficient? And set up an assay that enables detection of CRISPR cutting with 100s-1000s of sgRNAs over entire chromosome arms in living animals.
Grab a ☕ and let’s dive in. 🧵🧪 1/n
#CRISPR #geneediting
We (schierlab.bsky.social and Seelig lab) are very happy to share that our work has found a home at DevCell cellpress.bsky.social! Free access here: authors.elsevier.com/sd/article/S...
What are the features in 5′ UTRs that determine when and how much of a protein to make during embryogenesis?
What are the features in 5′ UTRs that determine when and how much of a protein to make during embryogenesis?
January 16, 2025 at 3:59 PM
We (schierlab.bsky.social and Seelig lab) are very happy to share that our work has found a home at DevCell cellpress.bsky.social! Free access here: authors.elsevier.com/sd/article/S...
What are the features in 5′ UTRs that determine when and how much of a protein to make during embryogenesis?
What are the features in 5′ UTRs that determine when and how much of a protein to make during embryogenesis?