RentmeisterLab
@rentmeisterlab.bsky.social
Researcher in Chemical Biology, Professor at LMU Munich
https://www.rentmeister-group.com/
Foto: LC Productions
https://www.rentmeister-group.com/
Foto: LC Productions
Pinned
Interesting paper by the group of @rentmeisterlab.bsky.social in @chemistryeurope.bsky.social. They describe photocaged guanosine-based dinucleotide tetraphosphates like m7Gp4G and their characteristics as RNA cap analogs. chemistry-europe.onl...
Photocaged Dinucleoside Tetraphosphates for Light‐Mediated Activation of 5′ Cap Interactions and Translation In Vitro
Photocaged dinucleoside tetraphosphates can be incorporated into mRNA by T7 RNA polymerase. Subsequent irradiation with light activates 5′ cap interactions and translation. These 5′ cap analogs are u...
chemistry-europe.onlinelibrary.wiley.com
Thanks @stephanhacker2.bsky.social ! Very happy to see our photocaged dinucleoside tetraphosphates published. Congrats to the entire team!
Interesting insights into publishing in Chem @cp-chem.bsky.social @cellpress.bsky.social by the editor in chief. Thank you Vjekoslav Dekaris for visiting the Chemistry Departement @lmumuenchen.bsky.social today!
October 30, 2025 at 8:05 PM
Interesting insights into publishing in Chem @cp-chem.bsky.social @cellpress.bsky.social by the editor in chief. Thank you Vjekoslav Dekaris for visiting the Chemistry Departement @lmumuenchen.bsky.social today!
Had a great day visiting Francoise Debart and Michael Smietana @smietana-m.bsky.social at IBMM in Montpellier. 😊 Thank you for the invitation, the hospitality and the scientific discussions. 🧬🤩
October 23, 2025 at 3:16 PM
Had a great day visiting Francoise Debart and Michael Smietana @smietana-m.bsky.social at IBMM in Montpellier. 😊 Thank you for the invitation, the hospitality and the scientific discussions. 🧬🤩
Reposted by RentmeisterLab
Join us as the first PhD student in my group! Based in the beautiful city of Münster, Germany, you will develop the chemo-enzymatic synthesis of modified nucleotides, which are used as building blocks of mRNA.
Here is the link:
stellen.uni-muenster.de/jobposting/6...
#chemsky #chembio
Here is the link:
stellen.uni-muenster.de/jobposting/6...
#chemsky #chembio
October 17, 2025 at 12:20 PM
Join us as the first PhD student in my group! Based in the beautiful city of Münster, Germany, you will develop the chemo-enzymatic synthesis of modified nucleotides, which are used as building blocks of mRNA.
Here is the link:
stellen.uni-muenster.de/jobposting/6...
#chemsky #chembio
Here is the link:
stellen.uni-muenster.de/jobposting/6...
#chemsky #chembio
Very much looking forward to this session highlighting SAM-dependent chemistry! 🤩 My first time at the Irsee Natural Product Symposium 😊
We are organizing a session on SAM-dependent enzymes at the 38th Irsee Natural Product Symposium, February 25-27, 2026. We are pleased to welcome the following speakers:
Prof. Andrea Rentmeister, Prof. Jörg Pietruszka, and Prof. Andreas Kirschning.
Please spread the news and join us in Irsee!
Prof. Andrea Rentmeister, Prof. Jörg Pietruszka, and Prof. Andreas Kirschning.
Please spread the news and join us in Irsee!
September 9, 2025 at 6:29 PM
Very much looking forward to this session highlighting SAM-dependent chemistry! 🤩 My first time at the Irsee Natural Product Symposium 😊
Very proud of my PhD students Wiebke Teich and Bayram Terzi, who explain their latest paper in this interview. #proudPI 🤩
💬 🧪 Behind the Science Interview with B. Terzi and W. Teich (@rentmeisterlab.bsky.social LMU Munich): Light-Activated mRNA Cap Analogs Allow Timed Control of mRNA Translation
Their work is published in @ChemistryEur - flagship journal of @ChemEurope
www.chemistryviews.org/light-activa...
Their work is published in @ChemistryEur - flagship journal of @ChemEurope
www.chemistryviews.org/light-activa...
August 7, 2025 at 3:07 PM
Very proud of my PhD students Wiebke Teich and Bayram Terzi, who explain their latest paper in this interview. #proudPI 🤩
Thanks @stephanhacker2.bsky.social ! Very happy to see our photocaged dinucleoside tetraphosphates published. Congrats to the entire team!
Interesting paper by the group of @rentmeisterlab.bsky.social in @chemistryeurope.bsky.social. They describe photocaged guanosine-based dinucleotide tetraphosphates like m7Gp4G and their characteristics as RNA cap analogs. chemistry-europe.onl...
Photocaged Dinucleoside Tetraphosphates for Light‐Mediated Activation of 5′ Cap Interactions and Translation In Vitro
Photocaged dinucleoside tetraphosphates can be incorporated into mRNA by T7 RNA polymerase. Subsequent irradiation with light activates 5′ cap interactions and translation. These 5′ cap analogs are u...
chemistry-europe.onlinelibrary.wiley.com
August 4, 2025 at 1:25 PM
Thanks @stephanhacker2.bsky.social ! Very happy to see our photocaged dinucleoside tetraphosphates published. Congrats to the entire team!
Great talk by Ronald Micura about Challenges in biological RNA chemistry @lmumuenchen.bsky.social 😀
July 14, 2025 at 12:02 PM
Great talk by Ronald Micura about Challenges in biological RNA chemistry @lmumuenchen.bsky.social 😀
Great work by @nicocorn.bsky.social - congratulations! 👍 Happy we could contribute a little bit. 😊
We systematically studied the substrate preferences of EbPPK2, determined the first crystal structure of the enzyme and used structure-guided engineering to enable efficient access to base-modified GTP and ATP analogues. #ChemSky #ChemBio
pubs.rsc.org/en/content/a...
pubs.rsc.org/en/content/a...
July 10, 2025 at 5:49 PM
Great work by @nicocorn.bsky.social - congratulations! 👍 Happy we could contribute a little bit. 😊
Great workshop of @angewandtechemie.bsky.social and @gdch.de today @lmumuenchen.bsky.social.Thanks for opening the editor's blackbox and the wonderful networking opportunity! 😊🙏
July 8, 2025 at 7:29 PM
Great workshop of @angewandtechemie.bsky.social and @gdch.de today @lmumuenchen.bsky.social.Thanks for opening the editor's blackbox and the wonderful networking opportunity! 😊🙏
Reminder for everyone currently in Munich area: Workshop tomorrow (Tue, July 08, 2025) by @angewandtechemie.bsky.social at @lmumuenchen.bsky.social. Please join! 🤩
We are looking forward to hosting @angewandtechemie.bsky.social at @lmumuenchen.bsky.social next week. Please spread the news and join us for this fantastic event! #chembio #chemsky #chemistry
July 7, 2025 at 11:13 AM
Reminder for everyone currently in Munich area: Workshop tomorrow (Tue, July 08, 2025) by @angewandtechemie.bsky.social at @lmumuenchen.bsky.social. Please join! 🤩
We are looking forward to hosting @angewandtechemie.bsky.social at @lmumuenchen.bsky.social next week. Please spread the news and join us for this fantastic event! #chembio #chemsky #chemistry
July 1, 2025 at 10:16 AM
We are looking forward to hosting @angewandtechemie.bsky.social at @lmumuenchen.bsky.social next week. Please spread the news and join us for this fantastic event! #chembio #chemsky #chemistry
Our latest article is now published in @ChemicalScience
🤩 We use light-mediated activation of translation of Cas9-mRNAfor gene editing with spatio-temporal control ⚡️🧬🧪🧫
pubs.rsc.org/en/content/a...
🤩 We use light-mediated activation of translation of Cas9-mRNAfor gene editing with spatio-temporal control ⚡️🧬🧪🧫
pubs.rsc.org/en/content/a...
pubs.rsc.org
June 30, 2025 at 2:07 PM
Our latest article is now published in @ChemicalScience
🤩 We use light-mediated activation of translation of Cas9-mRNAfor gene editing with spatio-temporal control ⚡️🧬🧪🧫
pubs.rsc.org/en/content/a...
🤩 We use light-mediated activation of translation of Cas9-mRNAfor gene editing with spatio-temporal control ⚡️🧬🧪🧫
pubs.rsc.org/en/content/a...
Enjoying the science & interactions at #SCNAC2025 😊 Thanks for the very nice foto 🙏
What do you call a group of nucleic acid chemists?
Suggestions welcome 🧬❤️
#SCNAC2025
@cjserpell.bsky.social @hoeferlab.bsky.social @boekhovenlab.bsky.social @rentmeisterlab.bsky.social @kgoepfrich.bsky.social @chlab.bsky.social
Suggestions welcome 🧬❤️
#SCNAC2025
@cjserpell.bsky.social @hoeferlab.bsky.social @boekhovenlab.bsky.social @rentmeisterlab.bsky.social @kgoepfrich.bsky.social @chlab.bsky.social
June 11, 2025 at 6:23 AM
Enjoying the science & interactions at #SCNAC2025 😊 Thanks for the very nice foto 🙏
Reposted by RentmeisterLab
If you are interested in #Biochemistry, #ChemBio and the related disciplines, already mark your calendars for the @gdchbiochem.bsky.social Conference in Würzburg on March 16th to 18th, 2026.
@gdch.de #chemsky
www.gdch.de/veranstaltun...
@gdch.de #chemsky
www.gdch.de/veranstaltun...
May 28, 2025 at 1:40 PM
If you are interested in #Biochemistry, #ChemBio and the related disciplines, already mark your calendars for the @gdchbiochem.bsky.social Conference in Würzburg on March 16th to 18th, 2026.
@gdch.de #chemsky
www.gdch.de/veranstaltun...
@gdch.de #chemsky
www.gdch.de/veranstaltun...
Reposted by RentmeisterLab
#DanioDigest (April 2025)
Community News:
Prof Wendy Bickmore @wbickmor.bsky.social elected as an International Member of the US National Academy of Sciences (NAS).
Prof Dr Andrea Rentmeister @rentmeisterlab.bsky.social receives 2024 Franco-German Georg Wittig - Victor Grignard Prize. (1/46)
Community News:
Prof Wendy Bickmore @wbickmor.bsky.social elected as an International Member of the US National Academy of Sciences (NAS).
Prof Dr Andrea Rentmeister @rentmeisterlab.bsky.social receives 2024 Franco-German Georg Wittig - Victor Grignard Prize. (1/46)
May 25, 2025 at 5:35 AM
#DanioDigest (April 2025)
Community News:
Prof Wendy Bickmore @wbickmor.bsky.social elected as an International Member of the US National Academy of Sciences (NAS).
Prof Dr Andrea Rentmeister @rentmeisterlab.bsky.social receives 2024 Franco-German Georg Wittig - Victor Grignard Prize. (1/46)
Community News:
Prof Wendy Bickmore @wbickmor.bsky.social elected as an International Member of the US National Academy of Sciences (NAS).
Prof Dr Andrea Rentmeister @rentmeisterlab.bsky.social receives 2024 Franco-German Georg Wittig - Victor Grignard Prize. (1/46)
Reposted by RentmeisterLab
🔥 Exciting online, free #chembio event on 28th May!!
Please join us online for the hybrid ESBOC Satellite meeting! Setup as a teaser to allow for accessibility and see some of the speakers that will attend ESBOC in Gregynog/Wales. To attend, please register by sending an email: lnkd.in/e-U7C6Jb
Please join us online for the hybrid ESBOC Satellite meeting! Setup as a teaser to allow for accessibility and see some of the speakers that will attend ESBOC in Gregynog/Wales. To attend, please register by sending an email: lnkd.in/e-U7C6Jb
May 23, 2025 at 3:38 PM
🔥 Exciting online, free #chembio event on 28th May!!
Please join us online for the hybrid ESBOC Satellite meeting! Setup as a teaser to allow for accessibility and see some of the speakers that will attend ESBOC in Gregynog/Wales. To attend, please register by sending an email: lnkd.in/e-U7C6Jb
Please join us online for the hybrid ESBOC Satellite meeting! Setup as a teaser to allow for accessibility and see some of the speakers that will attend ESBOC in Gregynog/Wales. To attend, please register by sending an email: lnkd.in/e-U7C6Jb
Thrilled to learn that the excellence cluster NUCLEATE will be funded 😃, and proud to be part of it. Congratulations to the coordinators and all contributers 👏👍
Die #Exzellenzcluster stehen fest: Heute hat die Exzellenzkommission 70 Projekte zur Förderung ausgewählt. 45 Cluster werden fortgesetzt, 25 neu eingerichtet. Die Förderung beginnt ab 1. Jan. 2026 für 7 Jahre, die Fördersumme beträgt insg. 539 Mio. €/Jahr. Die Liste: www.dfg.de/resource/blo... 1/3
May 22, 2025 at 3:37 PM
Thrilled to learn that the excellence cluster NUCLEATE will be funded 😃, and proud to be part of it. Congratulations to the coordinators and all contributers 👏👍
Reposted by RentmeisterLab
Increased ERC funding for top global researchers moving to Europe now confirmed
#Enlightenment #Facts #ProtectScience 🧪
erc.europa.eu/news-events/...
#Enlightenment #Facts #ProtectScience 🧪
erc.europa.eu/news-events/...
Increased ERC funding for top global researchers moving to Europe now confirmed
The European Research Council (ERC) decision to increase its support for leading researchers moving to Europe has today been formally adopted. On top of its standard grants, the ERC offers additional ...
erc.europa.eu
May 16, 2025 at 8:05 PM
Increased ERC funding for top global researchers moving to Europe now confirmed
#Enlightenment #Facts #ProtectScience 🧪
erc.europa.eu/news-events/...
#Enlightenment #Facts #ProtectScience 🧪
erc.europa.eu/news-events/...
Reposted by RentmeisterLab
Excited to see this out in @science.org today!! www.science.org/doi/10.1126/...
May 1, 2025 at 6:17 PM
Excited to see this out in @science.org today!! www.science.org/doi/10.1126/...
It was an honour to give a talk today in the historic lecture hall of Université Paris Cité, Faculté de Pharmacie after receiving the Wittig-Grignard Award yesterday. Thank you very much Bruno Sargueil and Mélanie Ethève-Quelquejeu for the invitation 🤩
April 30, 2025 at 12:18 PM
It was an honour to give a talk today in the historic lecture hall of Université Paris Cité, Faculté de Pharmacie after receiving the Wittig-Grignard Award yesterday. Thank you very much Bruno Sargueil and Mélanie Ethève-Quelquejeu for the invitation 🤩
Reposted by RentmeisterLab
Congratulations to all the authors of this paper, which just ranked in the top 10% of the most viewed papers published in ChemBioChem in 2023! We are very excited to be able to build on this amazing work in our FOR5596 research group.
@andexerlab.bsky.social @rentmeisterlab.bsky.social
@andexerlab.bsky.social @rentmeisterlab.bsky.social
Biomimetic S‐Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes**
The biomimetic regeneration system for S-adenosylmethionine (SAM) and SAM analogues presented is based on the salvage of the adenine moiety and in situ supply of d-ribose and polyphosphate. It is com...
chemistry-europe.onlinelibrary.wiley.com
April 17, 2025 at 8:39 AM
Congratulations to all the authors of this paper, which just ranked in the top 10% of the most viewed papers published in ChemBioChem in 2023! We are very excited to be able to build on this amazing work in our FOR5596 research group.
@andexerlab.bsky.social @rentmeisterlab.bsky.social
@andexerlab.bsky.social @rentmeisterlab.bsky.social
Come join our team! We have an opening for a research associate ("Ratsstelle"). Expertise in nucleotide chemistry and LC-MS is required. 👉 job-portal.lmu.de/jobposting/b... Deadline for application is June 01, 2025.
Research associate (Ratsstelle) for the duration of 5 years with the option to be tenured (m/f/x)
job-portal.lmu.de
April 15, 2025 at 2:02 PM
Come join our team! We have an opening for a research associate ("Ratsstelle"). Expertise in nucleotide chemistry and LC-MS is required. 👉 job-portal.lmu.de/jobposting/b... Deadline for application is June 01, 2025.
And here is the LMU press release for our article in Chem: www.lmu.de/en/newsroom/...
Organic syntheses: new chemistry challenges dogma
LMU researchers have developed a novel cofactor that broadens the use of methyltransferases – with great potential for research and applications.
www.lmu.de
April 10, 2025 at 6:54 PM
And here is the LMU press release for our article in Chem: www.lmu.de/en/newsroom/...
Ever wondered why prenylation and methylation use different cofactor scaffolds? We now show that the SAM scaffold enables both: Chimeric cofactors enable methyltransferase-catalyzed prenylation: Chem www.cell.com/chem/fulltex... Kudos to @nicocorn.bsky.social & Arne Hoffmann and all authors 👌👏🤩
Chimeric cofactors enable methyltransferase-catalyzed prenylation
In nature, many methyltransferases (C1) use S-adenosyl-l-methionine (AdoMet or SAM)
as a cofactor for methyl transfer, whereas prenyltransferases (C5) use dimethylallyl
diphosphate (DMAPP). We enginee...
www.cell.com
April 9, 2025 at 6:00 PM
Ever wondered why prenylation and methylation use different cofactor scaffolds? We now show that the SAM scaffold enables both: Chimeric cofactors enable methyltransferase-catalyzed prenylation: Chem www.cell.com/chem/fulltex... Kudos to @nicocorn.bsky.social & Arne Hoffmann and all authors 👌👏🤩
Congratulations to Dr. Katja Hartstock and Dr. Helena Schepers who successfully defended their PhD theses today. 👏🥂 So proud of my last two PhD students in Münster. 🤩All the best!
April 4, 2025 at 7:34 PM
Congratulations to Dr. Katja Hartstock and Dr. Helena Schepers who successfully defended their PhD theses today. 👏🥂 So proud of my last two PhD students in Münster. 🤩All the best!