Lev Tsypin, PhD
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ltsyp.in
Lev Tsypin, PhD
@ltsyp.in
・Postdoc working on weirdo microalgae
・Bigger than any known bacterium
・Views represent trillions of little cells
・🌐 https://ltsyp.in
・🌈🦠🔬🌱🌏
Pinned
I started this work 10 years ago as an undergrad in a "Computing for Biologists" class, and now it's finally out in the world! I'm very proud for it to be my first contributing author paper.

This work focuses on predicting and testing gene functions based on their co-expression, but there's more:
Inferring gene-pathway associations from consolidated transcriptome datasets: an interactive gene network explorer for Tetrahymena thermophila
Abstract. Although an established model organism, Tetrahymena thermophila remains comparatively inaccessible to high throughput screens, and alternative bi
doi.org
Reposted by Lev Tsypin, PhD
“You can get a other job, but you cannot get another soul”.
"We are speaking on behalf of hundreds of NIH staff who are standing up together to say: WE DISSENT.

I am so scared about doing this but I am trying to be brave for my kids because it's only gonna get harder to speak up."

Thank you to Dr. Jenna Norton and NIH scientists for your courage!
June 10, 2025 at 3:17 AM
I started this work 10 years ago as an undergrad in a "Computing for Biologists" class, and now it's finally out in the world! I'm very proud for it to be my first contributing author paper.

This work focuses on predicting and testing gene functions based on their co-expression, but there's more:
Inferring gene-pathway associations from consolidated transcriptome datasets: an interactive gene network explorer for Tetrahymena thermophila
Abstract. Although an established model organism, Tetrahymena thermophila remains comparatively inaccessible to high throughput screens, and alternative bi
doi.org
June 7, 2025 at 4:31 PM
Accepted with minor revisions! 🎉
It's now formatted more-or-less correctly!
March 12, 2025 at 7:19 PM
All of my old grievances and resentment toward faculty and administrators who asserted that science isn't political is bubbling to the surface.
January 22, 2025 at 11:28 PM
Timely for grad school admissions season...
Should research experience be used for selection into graduate school: A discussion and meta‐analytic synthesis of the available evidence
You have to enable JavaScript in your browser's settings in order to use the eReader.
onlinelibrary.wiley.com
January 18, 2025 at 6:24 PM
Reposted by Lev Tsypin, PhD
Had a great time talking to @atinygreencell.bsky.social abt my PhD work - small RNA transcriptome of rice gametes & zygotes. Please give his channel a follow. This podcast series of Sebastian is a great idea, and I found all previous episodes informative/inspirational. I hope mine is as well.
Tears In Rain Episode 6 is live!!
I hung out with another favorite plant biologist of mine,
@chenxinli2.bsky.social, where he regaled us with stories of his complex PhD project, pushing our understanding of the floral developmental transcriptome a bit further. Enjoy!
www.youtube.com/watch?v=vWj4...
Tears In Rain Ep6: Chenxin Li
YouTube video by Sebastian Cocioba
www.youtube.com
January 14, 2025 at 7:45 PM
What is the world coming to?
January 11, 2025 at 2:21 AM
Reposted by Lev Tsypin, PhD
Tears In Rain Episode 5 is live!!!

I hung out with @daniellebeckman.bsky.social where she told us about her experiences as a student in Brazil that shaped her current interests in viruses inside the human brain. I hope you enjoy! Please like and subscribe for more!

youtu.be/27AtqcYNHa8
Tears In Rain Ep5: Danielle Beckman
YouTube video by Sebastian Cocioba
youtu.be
January 8, 2025 at 11:41 PM
Grad school interview season is starting, and Sebastian's collecting biology PhD stories that I wish I had heard when I was figuring out where I should go. 🧪

It was a pleasure to share my experience--if I can help anyone think through things, please send me a message!
Episode 4 of Tears In Rain is live!!!

In this episode I hung out with Lev Tsypin (@ltsyp.in) and we talked about his adventures in microbiology during the pandemic and all the struggles that came with it. A nice dive into his project and lots of wisdom shared. Enjoy!
youtu.be/ucSORPmTrl0
Tears In Rain Ep4: Lev Tsypin
YouTube video by Sebastian Cocioba
youtu.be
January 8, 2025 at 6:11 PM
Just watched Moonstruck starring Cher and Nic Cage: 12/10 no notes, perfect film
January 8, 2025 at 6:23 AM
Thank you for inviting me on, Sebastian! This podcast is a wonderful project 🙂
Episode 4 of Tears In Rain is live!!!

In this episode I hung out with Lev Tsypin (@ltsyp.in) and we talked about his adventures in microbiology during the pandemic and all the struggles that came with it. A nice dive into his project and lots of wisdom shared. Enjoy!
youtu.be/ucSORPmTrl0
Tears In Rain Ep4: Lev Tsypin
YouTube video by Sebastian Cocioba
youtu.be
January 6, 2025 at 1:32 AM
Happy new year, everyone
January 1, 2025 at 5:33 PM
It's now formatted more-or-less correctly!
December 20, 2024 at 6:14 PM
When a journal rejects your manuscript but recommends that you transfer it to a subsidiary, how do you decide whether to do it or send the paper somewhere else?
December 20, 2024 at 4:33 PM
Reposted by Lev Tsypin, PhD
Infamous paper that popularized unproven COVID-19 treatment finally retracted

Study on hydroxychloroquine by Didier Raoult and colleagues gets pulled on ethical and scientific grounds
@cathleenogrady.bsky.social reports.

www.science.org/content/arti...
Infamous paper that popularized unproven COVID-19 treatment finally retracted
Study on hydroxychloroquine by Didier Raoult and colleagues gets pulled on ethical and scientific grounds
www.science.org
December 17, 2024 at 8:41 PM
Question for the bird people out there: how do hummingbirds avoid going into torpor while incubating their eggs?
December 17, 2024 at 6:02 PM
My first last-author paper is out as a preprint! 🧪

"Inferring gene-pathway associations from consolidated transcriptome datasets: an interactive gene network explorer for Tetrahymena thermophila"

I wanted to wait til bioRxiv finished formatting it, but I couldn't!

www.biorxiv.org/content/10.1...
December 17, 2024 at 1:06 AM
"My other car is a..."
December 15, 2024 at 11:45 PM
Eugenicists, eat your heart out
In a @currentbiology.bsky.social paper earlier this year, led by @laurawesseldijk.bsky.social, we analysed Beethoven’s genome with a polygenic index related to musicality, as a way to communicate limits of genetic predictions at the individual level & the complexity of links between DNA & behaviour:
Notes from Beethoven’s genome
Wesseldijk et al. compare the genomic information collected from Ludwig van Beethoven with population-based datasets used to quantify musical achievement.
www.cell.com
December 13, 2024 at 5:23 PM
Reposted by Lev Tsypin, PhD
In a @currentbiology.bsky.social paper earlier this year, led by @laurawesseldijk.bsky.social, we analysed Beethoven’s genome with a polygenic index related to musicality, as a way to communicate limits of genetic predictions at the individual level & the complexity of links between DNA & behaviour:
Notes from Beethoven’s genome
Wesseldijk et al. compare the genomic information collected from Ludwig van Beethoven with population-based datasets used to quantify musical achievement.
www.cell.com
December 5, 2024 at 8:45 PM
Reposted by Lev Tsypin, PhD
In one year, I genetically engineered the boring Arabidopsis into a beautiful ornamental flower 🧬🌹

Here is how and why I gave this model organism a visual upgrade 🧵(1/7)
December 12, 2024 at 11:24 AM
You've heard of classical eugenics.

Now presenting: corporate emotional eugenics!! 🎉
This is pure supervillain behavior
December 10, 2024 at 4:42 AM
Reposted by Lev Tsypin, PhD
This article, which contains not one critical commentator and reads like a press release, is a shocking dereliction of duty from one of our leading scientific publications 🧪 🔭
Finance billionaire & private astronaut Jared Isaacman has been nominated as the next head of Nasa.

How might he approach the job, and what challenges await him? Here’s the @science.org report 🧪🔭🚀
www.science.org/content/arti...
Trump picks billionaire astronaut to lead NASA
Jared Isaacman has twice flown in space in capsules made by Elon Musk’s rocket company
www.science.org
December 5, 2024 at 11:49 PM
This was so cathartic to watch: youtu.be/TwKpj2ISQAc

I had a very similar experience being given his "autobiographies" as a kid and again in college, and every time I felt like I was crazy for finding Feynman an intolerable ass
the sham legacy of Richard Feynman
YouTube video by Angela Collier
youtu.be
December 5, 2024 at 3:21 AM
Stunning!
December 4, 2024 at 7:26 AM