I love pugs, 🏐, and travel, but actually spend most of my free time figuring out parenting of young kids🪇
⚠️ Many non-lactose fermenters (especially Stenotrophomonas, Burkholderia, and Acinetobacter) can be very challenging to treat. ID consultation should be considered for invasive infections.
⚠️ Many non-lactose fermenters (especially Stenotrophomonas, Burkholderia, and Acinetobacter) can be very challenging to treat. ID consultation should be considered for invasive infections.
So what to do? Check out our ABX pearl on which ICH patients are best candidates for expanded empiric ABX coverage in CAP. ✅
#amssky #Idsky #medsky #pharmsky
IDSA Guidelines on the Treatment and Management of Complicated Urinary Tract Infections (cUTI)
#idsky
www.idsociety.org/practice-gui...
IDSA Guidelines on the Treatment and Management of Complicated Urinary Tract Infections (cUTI)
#idsky
www.idsociety.org/practice-gui...
doi.org/10.1016/j.ec...
#IDSky @eclinicalmed.bsky.social
doi.org/10.1016/j.ec...
#IDSky @eclinicalmed.bsky.social
✔️ 2017: switch to UA with reflex only of wbc>10
✔️2024: a creation of UCx order panel.
🚧 remove UA/UCx orders from surgery pre-op ordersets?
#IDsky #AMSsky
-Borderline urine WBC counts (6–10 cells/mL) may reflect dehydration and should be expected in patients with oliguria or anuria.
-Low urine WBC (WBC < 10) almost always excludes the diagnosis of UTI.
pubmed.ncbi.nlm.nih.gov/39181595/
pubmed.ncbi.nlm.nih.gov/39181595/
See useful tidbits on this interaction👇
See useful tidbits on this interaction👇
pyuria cutoff (in elderly♀️)"At a cutoff of 264 leuk/µL, sensitivity and specificity of microscopy were 88% (positive and negative likelihood ratio: 7.2 and 0.1, respectively). The commonly used cutoff of 10 leuk/µL had a poor specificity (36%) and a sensitivity of 100%."
@cjcrnich.bsky.social 😊 when you & I were on #Breakpoints we were asked whether there was a pyuria cutoff to help differentiate btw infection & colonization
Here may be one (in elderly ♀️ at least) #IDSky
academic.oup.com/cid/article/...
pyuria cutoff (in elderly♀️)"At a cutoff of 264 leuk/µL, sensitivity and specificity of microscopy were 88% (positive and negative likelihood ratio: 7.2 and 0.1, respectively). The commonly used cutoff of 10 leuk/µL had a poor specificity (36%) and a sensitivity of 100%."
Welcome to Blue Sky! 🌟 #AMSsky #IDsky #pharmsky #skyRX #medsky
@idsainfo.bsky.social
@sidpharm.bsky.social
#IDsky
📋 Q: My patient presented with septic shock from a urinary source, blood cultures positive for E. coli.
What is the duration of therapy, and must I use IV to complete the course for Enterobacterales bacteremia? 🤔
#IDsky
@idsainfo.bsky.social
@sidpharm.bsky.social
#IDsky
Me: Pick anything. You're just about done with treatment!
...1g q8h
#IDsky #medsky #pharmsky #RXsky
74 hospitals in 7 countries
3,608 patients
A 7-day course of antibiotics for hospitalized patients with bloodstream infections was non inferior to 14d within a 4% prespecified margin for mortality at 90 days #idsky
www.nejm.org/doi/full/10....
#IDSky
onlinelibrary.wiley.com/doi/10.1111/...
#IDSky
onlinelibrary.wiley.com/doi/10.1111/...