Revathi Balasubramanian
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ladyglaucoma.bsky.social
Revathi Balasubramanian
@ladyglaucoma.bsky.social
Assistant Professor of Ophthalmic Sciences
@Columbia University, Developmental ocular biology, Mom-scientist, Chai lover, All things women-in-science, Immigrant.
Pinned
Excited to share this study! We created a developmental atlas of the anterior segment of the eye and provide crucial molecular information that guides the development of Schlemm’s canal and trabecular meshwork cell subtypes. www.biorxiv.org/content/10.1...
Single-Cell Characterization of Anterior Segment Development: Cell Types, Pathways, and Signals Driving Formation of the Trabecular Meshwork and Schlemm's Canal
Morphogenesis of the anterior segment (AS) is crucial for healthy ocular physiology and vision but is only partially understood. The Schlemm's canal (SC) and trabecular meshwork (TM) are essential dra...
www.biorxiv.org
This Diwali I am hoping that the good truly does triumph over all evil, and soon. Happy Diwali to those celebrating!
a greeting card for happy diwali with fireworks and candles
ALT: a greeting card for happy diwali with fireworks and candles
media.tenor.com
October 20, 2025 at 6:29 PM
Reposted by Revathi Balasubramanian
My department at Emory is a hiring a tenure-track neuroscientist!

Anyone who's talked to me in the last 4 years knows I cannot say enough good things about my dept and the neuroscience community here. My colleagues are so wonderfully supportive. Postdocs, please apply!

apply.interfolio.com/174371
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
September 30, 2025 at 6:25 PM
Reposted by Revathi Balasubramanian
#FluorescenceFriday
Strand and branch pericytes surround the vessels of the retina👁️🔬

color=depth
@flaumeye.bsky.social @urneuroscience.bsky.social @cvsuor.bsky.social @uofrbme.bsky.social @urochestersmd.bsky.social
September 12, 2025 at 7:10 PM
Reposted by Revathi Balasubramanian
Our latest manuscript is out, and this one tackles the problem of cellular aging in the retina, using comparative multiomic analysis of zebrafish, mouse, and humans. What led us to work on aging after studying development and regeneration? Explainer follows./1
www.biorxiv.org/content/10.1...
Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal aging.
Biological age is a major risk factor in the development of common degenerative retinal diseases such as age-related macular degeneration and glaucoma. To systematically characterize molecular mechani...
www.biorxiv.org
September 12, 2025 at 7:04 PM
Excited to share this study! We created a developmental atlas of the anterior segment of the eye and provide crucial molecular information that guides the development of Schlemm’s canal and trabecular meshwork cell subtypes. www.biorxiv.org/content/10.1...
Single-Cell Characterization of Anterior Segment Development: Cell Types, Pathways, and Signals Driving Formation of the Trabecular Meshwork and Schlemm's Canal
Morphogenesis of the anterior segment (AS) is crucial for healthy ocular physiology and vision but is only partially understood. The Schlemm's canal (SC) and trabecular meshwork (TM) are essential dra...
www.biorxiv.org
August 22, 2025 at 1:27 AM
Reposted by Revathi Balasubramanian
Please repost and share
July 31, 2025 at 6:54 PM
Reposted by Revathi Balasubramanian
The NIH was healthiest when pay lines were in the 20th percentile range.

We are headed into an environment where pay lines are in the 5% range.

In my entire career, I’ve only had 3 grants that scored better than 5%. And my lab is considered a successful one.

This is going to destroy science.
July 28, 2025 at 8:12 PM
Paper alert! With co-first authors Nick Tolman and @taiboli.bsky.social , we profile trabecular meshwork cells using single-cell RNA + ATAC seq, identify mitochondrial dysfunction in an early-onset glaucoma model, and use Vitamin B3 to protect against nerve damage.
elifesciences.org/reviewed-pre...
Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment
elifesciences.org
July 29, 2025 at 2:36 PM
Reposted by Revathi Balasubramanian
Hi all, we got a grant for a cool project that will follow up of our paper published a few months ago (see below). We will explore how light acts as a morphogen to instruct PCP. If you are looking for a postdoc position and interested in this topic, please reach out!
ICYMI our latest paper is now out officially in print (is there still such thing?). And since Dev Cell @cellpress.bsky.social did not select our submission for cover, I post it here. A really cool illustration from my son Zack. www.cell.com/developmenta...
July 25, 2025 at 9:08 PM
Reposted by Revathi Balasubramanian
On Sunday I will cycle 50 km to raise money to support research to prevent blindness. If you can, please sponsor me! fightingblindness.akaraisin.com/ui/MOVEFORSI...
fightingblindness.akaraisin.com
June 20, 2025 at 5:37 PM
In more good new for the lab.. Just heard that we got a grant from The Glaucoma Foundation for our work on early onset glaucomas! Thank you TGF.
June 13, 2025 at 1:58 PM
Reposted by Revathi Balasubramanian
Ok, that’s it. Here’s the link again: joinus.cuimc.columbia.edu/participant/.... I know there's a lot of chaos right now, and it’s hard to know which crisis to focus your attention on and where to devote your time/resources. So if you decided to support my lab, I really do appreciate it! 9/9
June 10, 2025 at 4:28 PM
Just got word that I got the RPB career development award. It feels weird to be happy when science funding is under attack. But one small win, one more day of science (or 4 more years). Thank you, Research to Prevent Blindness foundation.
June 4, 2025 at 6:02 PM
Reposted by Revathi Balasubramanian
🚨 Final Reminder! 🚨
Don't miss your chance to share your research at the ISER BrightFocus Glaucoma Meeting 2025!
📅 Abstract Submission Deadline: May 27, 2025
🔗 iserbrightfocusglaucoma.org/abstract-sub...
@iser.bsky.social @brightfocus.bsky.social
Abstract Submission – Iser/Bright Focus Glaucoma Symposium
iserbrightfocusglaucoma.org
May 22, 2025 at 7:40 PM
Reposted by Revathi Balasubramanian
The pact of the federal govt with universities was not a handout. It was a strategic decision to boost US leadership in technology, defense, and health. And it paid dividends. In tech, internet, in cancer drugs (for example), No other sector has invested in high risk high reward ideas like US govt.
May 10, 2025 at 2:42 AM
Reposted by Revathi Balasubramanian
We have updated our database of funding opportunities for Early-Career Researchers (private foundations, federal, international)

We have 456 entries, for which we provide $ amount, deadline, eligibility criteria, etc.

Download this massive database here for free: research.jhu.edu/rdt/funding-...
May 7, 2025 at 4:46 PM
These are my people! 🫶
Celebrating a successful Utah Vision Science Symposium! A day of amazing science and people!
May 3, 2025 at 10:00 PM
Reposted by Revathi Balasubramanian
Our latest manuscript (7 years in the works) tackles the question of how diurnal ground squirrels evolved a cone-dominant retina, in contrast to the ancestral rod-dominant retina retained by virtually all other mammals./1
www.biorxiv.org/content/10.1...
Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.
Evolutionary adaptation to diurnal vision in ground squirrels has led to the development of a cone-dominant retina, in stark contrast to the rod-dominant retinas of most mammals. The molecular mechani...
www.biorxiv.org
April 29, 2025 at 11:06 AM
Reposted by Revathi Balasubramanian
Deaths from heart disease down 75%, that’s NIH.

Deaths from stroke down 75%, that’s NIH.

HIV/AIDS no longer a death sentence, that’s NIH.

99% of FDA approved drugs in the last decade, that’s NIH.

Please show this video to anyone who doesn’t understand why the NIH is so important.
April 28, 2025 at 5:20 PM
Will be at #ARVO next week and would love to catch up, vision science folk! I am also presenting a talk on May 6th on trascriptomics in aging and glaucoma.
April 27, 2025 at 3:54 PM
Reposted by Revathi Balasubramanian
Wanna grow organoids to understand human retinal development as a research assistant?

Wanna help run the lab as a lab manager?

The Johnston lab is hiring a research assistant/lab manager.

If you are interested, please apply (also please share!):

jobs.jhu.edu/job/Baltimor...
Research Technologist
Research Technologist
jobs.jhu.edu
April 22, 2025 at 2:06 PM
Reposted by Revathi Balasubramanian
Scientists must explore R&D careers beyond U.S. in current climate. My @insidehighered.com article today outlines approaches to explore global research careers for U.S. trained early-career scientists, particularly international scientists. 1/2

www.insidehighered.com/opinion/care...
Approaches for Finding International Research Jobs (opinion)
For U.S.-trained scientists searching for early-career research opportunities in other countries, Sonali Majumdar suggests some approaches to consider.
www.insidehighered.com
April 21, 2025 at 12:59 PM
Reposted by Revathi Balasubramanian
Exclusive: Weeks after President Donald Trump’s administration ordered NIH to pull $250 million in biomedical research grants to Columbia University, the agency is freezing all remaining grant money owed to the university until further notice. scim.ag/4if5Rg1
NIH freezes all research grants to Columbia University
Amid negotiations with Trump, the university could risk losing nearly $700 million
scim.ag
April 9, 2025 at 6:56 PM
Reposted by Revathi Balasubramanian
See, if you just cooperate with the administration and comply, it all turns out OK...

www.science.org/content/arti...
NIH freezes all research grants to Columbia University
Amid negotiations with Trump, the university could risk losing nearly $700 million
www.science.org
April 9, 2025 at 9:31 PM
Spotted Valerie Wallace in this. Need to bring her here to bluesky. Or maybe we move to Canada? @blockintheback.bsky.social @michelcayouette.bsky.social @flyeyelab.bsky.social
Today UHN launches the Canada Leads 100 Challenge! 🇨🇦💯

We’re making an ambitious investment to recruit 100 world-leading scientists. Together, we'll drive the future of health research and position Canada as a leader in global innovation!

Learn more:
www.uhn.ca/corporate/Ab...
April 7, 2025 at 4:40 PM