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schalleklab.bsky.social
Schallek Lab
@schalleklab.bsky.social
410 followers 480 following 82 posts
At the junction of optics, neuroscience, ophthalmology and bioengineering.

https://aria.cvs.rochester.edu/our_work/blood_flow.html
Posts Replies Media Videos
Reposted by Schallek Lab
arvoinfo.bsky.social
@arvoinfo.bsky.social members, remember to cast your vote for the 2025 ARVO Scientific Image Contest! Review the fabulous finalists and select your favorite by Nov. 14: https://bit.ly/4mNNbq8
Graphic banner for the 2025 ARVO Scientific Image Contest Finalists featuring colorful swirling ribbons on a black background.
November 12, 2025 at 5:54 PM
schalleklab.bsky.social
#FluorescenceFriday
@arvoinfo.bsky.social scientific image contest
(voting link below)

👇👁️👇: microglia imaged in the retina, color-coded for depth
ARVO Image Contest
www.arvo.org/news/scienti...

@flaumeye.bsky.social @cvsuor.bsky.social @urochestersmd.bsky.social @urneuroscience.bsky.social
November 7, 2025 at 5:11 AM
schalleklab.bsky.social
This is the way...
Happy Halloween from @cvsuor.bsky.social

@flaumeye.bsky.social @urochester.bsky.social @urneuroscience.bsky.social @marcoslabur.bsky.social @uofrbme.bsky.social
October 31, 2025 at 5:16 PM
schalleklab.bsky.social
happening tomorrow! Full day covering latest applications and advances in the Center for Visual Science
@cvsuor.bsky.social @flaumeye.bsky.social @urochester.bsky.social
October 23, 2025 at 9:29 PM
schalleklab.bsky.social
#FluorescenceFriday
Watch to the end! Immune cells in the retina remain flat until damage is detected. Cells change their shape and dive deep in response to damage (pink cell)
@cvsuor.bsky.social @urochester.bsky.social
@flaumeye.bsky.social @uofrbme.bsky.social
elifesciences.org/articles/98662
October 9, 2025 at 9:57 PM
Reposted by Schallek Lab
leahgjohnston.bsky.social
My boss/mentor Teresa Puthussery won a MacArthur genius grant today! She shares the award with Oakland novelist Tommy Orange (read There There! It's awesome!), resource recovery chemist William Tarpeh, and 22 others. Congratulations Teresa! www.macfound.org/fellows/clas...
Teresa Puthussery
Exploring how neural circuits of the retina encode visual information for the human brain.
www.macfound.org
October 8, 2025 at 5:58 PM
schalleklab.bsky.social
Austin Roorda @roordalab.bsky.social delivering the richly deserved Boynton Lecture @optica-fvm.bsky.social
@optica.org

A tremendous journey with an incredible cast of characters that brought the world high resolution retinal imaging, Oz Vision and olo
October 6, 2025 at 9:26 PM
schalleklab.bsky.social
Congratulations to Susana Marcos @marcoslabur.bsky.social receiving the Tillyer Award @optica.org Fall Vision Meeting in #minneapolis
Introduced by Steve Burns, her mentor from postdoctoral days.
@cvsuor.bsky.social @flaumeye.bsky.social @urochestersmd.bsky.social
October 4, 2025 at 12:49 PM
Reposted by Schallek Lab
flaumeye.bsky.social
Our next researcher at the Optica meeting is Jesse B. Schallek, Ph.D., who along with his lab, studies how blood flows through the vessels in the retina. They aim to understand how changes in this neural-vascular network contribute to retinal diseases and vision loss.
Flaum Researcher Jesse Schallek, Ph.D., posing in front of optical research equipment, in front of a white board and an optical imaging poster.
October 3, 2025 at 7:16 PM
schalleklab.bsky.social
Microglia (white/green) are immune cells that live in specific layers in the retina.
In response to injury, they migrate into location of damage.

doi.org/10.7554/eLif...

@flaumeye.bsky.social @cvsuor.bsky.social @urneuroscience.bsky.social @uofrbme.bsky.social
@urochestersmd.bsky.social
September 30, 2025 at 2:42 PM
Reposted by Schallek Lab
cvsuor.bsky.social
#cvstoday 3:00 pm, Helen Wood Hall SON Auditorium, 1W-304
Knill Lecture: Daniel Wolpert, Columbia University
Computational principles underlying the learning of sensorimotor repertoires

There will be a reception immediately following the lecture in Helen Wood Hall 1W-300.
September 24, 2025 at 12:28 PM
schalleklab.bsky.social
#FluorescenceFriday
Strand and branch pericytes surround the vessels of the retina👁️🔬

color=depth
@flaumeye.bsky.social @urneuroscience.bsky.social @cvsuor.bsky.social @uofrbme.bsky.social @urochestersmd.bsky.social
September 12, 2025 at 7:10 PM
Reposted by Schallek Lab
flaumeye.bsky.social
Meet Dr. Sara Patterson, a researcher at Flaum who is participating in the Emerging Vision Scientist Program.

Her lab studies how the eye communicates with the brain. This groundbreaking work is paving the way for new treatments to restore vision.

#VisionResearch #VisionRestoration #EyeHealth
September 10, 2025 at 6:31 PM
Reposted by Schallek Lab
flaumeye.bsky.social
Thank you, Rep. Morelle, for visiting the Flaum Eye Institute to discuss and see firsthand how NEI-funded research improves patient care and drives innovation in ophthalmology. We are grateful for your support and recognition of the important role federally funded research plays.
Congressman Joe Morelle posing in a group photo with members of the Flaum Eye Institute.
September 8, 2025 at 9:12 PM
schalleklab.bsky.social
She did it!
Very proud to announce: the newly minted Dr. Fei Shang, PhD in Neuroscience.
Vascular insights... to what gives us sight!
@urneuroscience.bsky.social @flaumeye.bsky.social @cvsuor.bsky.social @urmed.bsky.social
September 5, 2025 at 9:51 PM
schalleklab.bsky.social
🧠Today🔬
PhD Thesis defense by Schallek Lab student Fei Shang!
1pm K-207 conference room, URMC.

Come to learn about how vessels nourish the eye.👁️
@cvsuor.bsky.social @urmed.bsky.social @urneuroscience.bsky.social @flaumeye.bsky.social
September 5, 2025 at 4:17 PM
Reposted by Schallek Lab
flaumeye.bsky.social
We’re thrilled to share that our very own Matt Cavanaugh has been chosen for the Emerging Vision Scientist Program, where he will advocate for congressional support of vision research. We’re so proud of all he has accomplished so far and for his commitment to advancing vision care!
September 3, 2025 at 2:20 PM
schalleklab.bsky.social
#FluorescenceFriday
NEUTROPHILS are rare immune cells flowing within trillions of blood cells of the body. Using #AdaptiveOptics cameras, we directly image fluorescent neutrophils in the vessels of the eye

doi.org/10.7554/eLif...
@flaumeye.bsky.social @cvsuor.bsky.social @urneuroscience.bsky.social
August 14, 2025 at 8:51 PM
Reposted by Schallek Lab
urneuroscience.bsky.social
You don't have to be a scientist to think lasers are cool😎
But the 👨‍🔬 in @schalleklab.bsky.social have cool lasers
👇Lab mngr Derek Power led research using the adaptive optics camera, a laser engine, & found how immune cells in the eye respond differently when the retina is injured
👉 bit.ly/4fB7y7P
Lab manager Derek Power is photographed in his lab in the University of Rochester’s Flaum Eye Institute // photo by J. Adam Fenster / University of Rochester Adaptive optics imaging table pioneered at the Flaum Eye Institute. // photo by J. Adam Fenster / University of Rochester
August 14, 2025 at 1:20 PM
schalleklab.bsky.social
Love this...
Here's a chunk of mine in peer-reviewed form 😉
@cvsuor.bsky.social @flaumeye.bsky.social
August 8, 2025 at 3:33 PM
schalleklab.bsky.social
EXCITATION
At the heart of our adaptive optics camera is a laser engine. A beam of light scans the retina to image the eye with single cell resolution. @cvsuor.bsky.social
#FluorescenceFriday
#AOSLO
@urochester.bsky.social
@urochestersmd.bsky.social
@flaumeye.bsky.social
@urneuroscience.bsky.social
laser beam excites fluorescence in the eye
August 7, 2025 at 4:46 PM
Reposted by Schallek Lab
urneuroscience.bsky.social
👇3D look at adaptive optics imaging table in the @schalleklab.bsky.social This tool allowed researchers to discover that microglia, not neutrophils, a type of white blood cells, respond to photoreceptor damage in the retina

Read more: bit.ly/4mmmPvx
#URochesterResearch @flaumeye.bsky.social
July 29, 2025 at 8:01 PM
schalleklab.bsky.social
✨Our newest eLife paper is out!✨
👉 elifesciences.org/articles/98662
When retinal cells die, who cleans up?
Non-invasive imaging shows microglia👇 rush to help but don’t recruit neutrophils from the bloodstream. @urneuroscience.bsky.social @cvsuor.bsky.social
@elife.bsky.social #FluorescenceFriday
July 24, 2025 at 8:46 PM
Reposted by Schallek Lab
urneuroscience.bsky.social
#URochesterResearch by @schalleklab found that when photoreceptor cells in the retina are damaged, the brain’s immune cells respond, and neutrophils are not recruited to help despite passing through nearby blood vessels

via eLife 👉 elifesciences.org/articles/98662
@cvsuor.bsky.social
This finding has high implications for what happens to millions of Americans who suffer vision loss through loss of photoreceptors. Jesse Schallek, PhD, associate professor of Ophthalmology
July 24, 2025 at 6:07 PM
schalleklab.bsky.social
Thrilled to have been selected for the @cvsuor.bsky.social pilot award with additional support from @flaumeye.bsky.social.
Our collaboration with Wojtovich lab will study mitochondria survival and anatomy in the diabetic retina. @urochester.bsky.social @urochestersmd.bsky.social
cvsuor.bsky.social UR Center for Visual Science @cvsuor.bsky.social · Jul 23
1of2) Announcing the awardees of the 2025 CVS Pilot Funds for Vision Research: Ania Majewska & Houhui Xia; Jesse Schallek & Andrew Wojtovich; David Williams, Jude Mitchell, Juliette McGregor, Sara Patterson, Bill Merigan.
July 23, 2025 at 4:03 PM