Jonathan Friedman
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labfriedman.bsky.social
Jonathan Friedman
@labfriedman.bsky.social
Associate Professor in Cell Biology at UTSW, studying how organelles are shaped and organized
Reposted by Jonathan Friedman
Excited to share that we are hiring a research assistant for my lab at UTSW in Dallas (www.nils-burger-lab.com). Please share with your mentees.
utsw.taleo.net/careersectio...

We are also looking for motivated, curious, and enthusiastic postdoctoral fellows!
Research Assistant I, Pharmacology
Click the link provided to see the complete job description.
utsw.taleo.net
October 16, 2025 at 4:25 PM
Thrilled to announce my official promotion to associate professor with tenure at UTSW! So grateful to all the trainees in the lab for their hard work and proud of their accomplishments over the last several years. This an individual recognition but truly a team effort!
September 3, 2025 at 1:31 PM
Does anyone have a favorite mNeonGreen antibody that works well for western and IPs?
August 13, 2025 at 3:32 PM
Reposted by Jonathan Friedman
Finally, we find that presequence strength influences yeast metabolism in a model of COX4 deletion. When fused to a leaderless COX4, only presequences that promote “strong” import behavior restore respiratory growth to wild-type levels. 8/n
May 29, 2025 at 9:18 PM
Reposted by Jonathan Friedman
Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented @washubbsb.bsky.social graduate student Youmian Yan. A 🧵

www.biorxiv.org/content/10.1...
Mitochondrial presequences harbor variable strengths to maintain organellar function
Hundreds of mitochondrial-destined proteins rely on N-terminal presequences for organellar targeting and import. While generally described as positively charged amphipathic helices, presequences lack ...
www.biorxiv.org
May 29, 2025 at 9:18 PM
Reposted by Jonathan Friedman
Niemi lab and @washubbsb.bsky.social graduate student Youmian Yan gave a fantastic presentation on her work at the @asbmb.bsky.social meeting in Chicago! #ProudPI (photo credit to @kerikozul.bsky.social)
April 14, 2025 at 4:13 PM
Reposted by Jonathan Friedman
This is a very sad day. Shock, despair, disappointment, disbelief... These only scratch the surface in describing this decision and how I feel. I began my career in Parkinson's research in Richard's lab. What happens now to all the trainees still there?
April 2, 2025 at 7:21 AM
Reposted by Jonathan Friedman
Come to St. Louis this summer for the United Mitochondrial Disease Foundation MitoMed 2025 Conference! We have a fantastic line up with lots of opportunities for short talks. We're also running a Masterclass for Early Career Investigators. More info here: www.umdfconference.org
UMDF Conference
www.umdfconference.org
March 28, 2025 at 1:22 PM
Reminder to join us tomorrow at 12pm ET!
Join us March 26th at 12pm ET - @asbmb.bsky.social LRD seminar series.

We have two great mitochondria-focused lipid talks planned from @jasoncasler.bsky.social from @lllackner.bsky.social's lab and Kailash Venkatraman from @ibudin.bsky.social's lab.

Register here! www.asbmb.org/meetings-eve...
Lipid Research Division Seminar Series
March 26, 2025 | 12 p.m. Eastern
www.asbmb.org
March 25, 2025 at 3:36 PM
Join us March 26th at 12pm ET - @asbmb.bsky.social LRD seminar series.

We have two great mitochondria-focused lipid talks planned from @jasoncasler.bsky.social from @lllackner.bsky.social's lab and Kailash Venkatraman from @ibudin.bsky.social's lab.

Register here! www.asbmb.org/meetings-eve...
Lipid Research Division Seminar Series
March 26, 2025 | 12 p.m. Eastern
www.asbmb.org
March 14, 2025 at 5:35 PM
Some good news (and fresh science) to break things up! Our work identifying a subpopulation of compositionally unique mitochondria that localize to filopodia and promote cell migration is now @currentbiology.bsky.social! Led by fantastic @madeleinempavey.bsky.social!

www.cell.com/current-biol...
Compositionally unique mitochondria in filopodia support cellular migration
Marlar-Pavey et al. determine that a subpopulation of compositionally unique mitochondria, METEORs, dynamically localize to filopodia. Loss of mitochondrial targeting to filopodia correlates with a re...
www.cell.com
February 19, 2025 at 4:06 PM
An excellent opportunity!
Some good news: applications are open for the Weill Institute Emerging Scholars Symposium @ Cornell! Senior PhD students and, now, postdocs interested in networking & presenting their work in cell & molecular biology at Cornell should apply by Apr 14. Please repost! wicmb.cornell.edu/emerging-sch...
February 19, 2025 at 3:54 PM
Reposted by Jonathan Friedman
It’s so nice to be able to celebrate something this week. Newest work from the group! How are nuclear contents delivered to the cytosolic autophagy machinery while maintaining nuclear integrity? Nuclear envelope gymnastics! Cool role for Dnm1/Drp1. www.nature.com/articles/s41...
A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope - Nature Cell Biology
Mannino et al. provide a quantitative and ultrastructural timeline of nucleophagy in yeast with lattice light sheet microscopy and correlative light and electron tomography. They identify a role for d...
www.nature.com
February 7, 2025 at 12:12 PM
Reposted by Jonathan Friedman
In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:
January 17, 2025 at 6:43 PM
A big congrats to Alia on a successful thesis defense! @themitotracker.bsky.social gave an excellent talk and did the lab proud! 🥳🎉🍾
January 16, 2025 at 11:29 PM
Reposted by Jonathan Friedman
New: @themitotracker.bsky.social et al. from @labfriedman.bsky.social identify a mitochondrial inner membrane protein that marks and facilitates a subset of sites of mitochondrial fission in human cells. rupress.org/jcb/article/...
December 24, 2024 at 5:15 PM
Looking for some holiday reading material? Our latest paper identifying a new player in mitochondrial fission is now out @jcellbiol.bsky.social! A wonderful early present to see this now online!

rupress.org/jcb/article/...
Functionally conserved inner mitochondrial membrane proteins CCDC51 and Mdm33 demarcate a subset of fission events | Journal of Cell Biology | Rockefeller University Press
Edington et al. determine that Mdm33 and CCDC51 are functionally conserved mitochondrial inner membrane proteins that are required for normal mitochondrial
rupress.org
December 24, 2024 at 8:07 PM
Reposted by Jonathan Friedman
I’m ultra excited about our preprints on mitochondrial pearling. In two concurrent collaborative studies with @wallaceucsf.bsky.social, we investigated its consequences on mtDNA nucleoids (led by @jclandoni.bsky.social) & its biophysical causes (led by @gavsturm.bsky.social). Funders HFSP, ERC, SNSF
December 23, 2024 at 4:11 PM
Reposted by Jonathan Friedman
Our executive editor with Alia Edington @themitotracker.bsky.social from @labfriedman.bsky.social, winner of the 2024 Alan Hall Travel Award! 👉 Be sure to catch Alia's talk today at #CellBio2024! Read about his year's winners: https://buff.ly/4gtpqRk
December 16, 2024 at 2:28 PM
Reposted by Jonathan Friedman
Excited to announce that I was awarded the Alan Hall Travel Award from @jcellbiol.bsky.social to attend #CellBio2024 this weekend! If you're attending this year, please join me at my poster or my talk (details below) to learn about my story on novel mediators of mitochondrial dynamics!
🎉 Congratulations to Alia Edington @themitotracker.bsky.social the winner of 2024 Alan Hall Travel Award! Alia is a graduating PhD student from @labfriedman.bsky.social.
👉 Be sure to catch Alia's talk during #CellBio2024!
Read about his year's winners: https://buff.ly/4ffCQz8
December 12, 2024 at 5:18 PM
Congrats Alia! 🎉🎉 Well deserved!
🎉 Congratulations to Alia Edington @themitotracker.bsky.social the winner of 2024 Alan Hall Travel Award! Alia is a graduating PhD student from @labfriedman.bsky.social.
👉 Be sure to catch Alia's talk during #CellBio2024!
Read about his year's winners: https://buff.ly/4ffCQz8
December 11, 2024 at 7:03 PM
So proud of Alia Edington @themitotracker.bsky.social for winning the JCB Alan Hall Travel award to attend ASCB! Thank you @jcellbiol.bsky.social for recognizing the hard work of our trainees!

Be sure to check out Alia's talk 5pm Mon. in the organelle subgroup or at poster B143 Sun. 11:15!
December 9, 2024 at 6:15 PM
As you're planning out your ASCB schedule be sure to attend the organelle-focused special interest group hosted by @nieminm.bsky.social and myself Mon. 12/16 at 5pm

Come hear a fantastic lineup of speakers including @walterwchen.bsky.social @themitotracker.bsky.social @lianjiejerrywei.bsky.social
December 9, 2024 at 6:04 PM
Happy to have my first post on this site be to share the news that our amazing student Alia will be presenting her work on mitochondrial fission at MitoChats Thursday (10am US central time)! Be sure to check it out!
MITOtalks have not made it here (yet) but we are excited to host two fantastic trainee talks this week on MITOchats - Alia Edington from Friedman lab at UTSW and David Eberhardt from Chaudhuri at UUtah - visit www.mitotalks.org for more info and zoom link to join! #mitochondria please share!
November 12, 2024 at 7:36 PM