Komander Lab
@komanderlab.bsky.social
We love #ubiquitin. Lab researching ubiquitination in health and disease @WEHI-research. Posts are by Komander lab members.
A big year for the lab!
We hosted Australia’s first ubiquitin summit in Lorne,
Published the structure of PINK1 on a mitochondrial translocase array,
Reported a new PLpro inhibitor for long COVID,
Celebrated 3 PhD and 1 honours completions,
Went on a lab footy trip, 🏈
Won the Eureka prize!! 🏆
We hosted Australia’s first ubiquitin summit in Lorne,
Published the structure of PINK1 on a mitochondrial translocase array,
Reported a new PLpro inhibitor for long COVID,
Celebrated 3 PhD and 1 honours completions,
Went on a lab footy trip, 🏈
Won the Eureka prize!! 🏆
December 23, 2025 at 1:25 AM
A big year for the lab!
We hosted Australia’s first ubiquitin summit in Lorne,
Published the structure of PINK1 on a mitochondrial translocase array,
Reported a new PLpro inhibitor for long COVID,
Celebrated 3 PhD and 1 honours completions,
Went on a lab footy trip, 🏈
Won the Eureka prize!! 🏆
We hosted Australia’s first ubiquitin summit in Lorne,
Published the structure of PINK1 on a mitochondrial translocase array,
Reported a new PLpro inhibitor for long COVID,
Celebrated 3 PhD and 1 honours completions,
Went on a lab footy trip, 🏈
Won the Eureka prize!! 🏆
Reposted by Komander Lab
It’s hard to believe that #AusUb2025 has already come to an end 😢. Don’t worry though - we’ll still be posting our speaker interviews in the next couple of days.
Here’s what Sonja Lorenz thought of the Australian Ubiquitin Summit. 👇
Here’s what Sonja Lorenz thought of the Australian Ubiquitin Summit. 👇
November 25, 2025 at 7:07 AM
It’s hard to believe that #AusUb2025 has already come to an end 😢. Don’t worry though - we’ll still be posting our speaker interviews in the next couple of days.
Here’s what Sonja Lorenz thought of the Australian Ubiquitin Summit. 👇
Here’s what Sonja Lorenz thought of the Australian Ubiquitin Summit. 👇
Reposted by Komander Lab
Today we have Brenda Schulman, Director of the Department of Molecular Machines and Signalling at Max Planck Institute of Biochemistry, as our interviewee at #AusUb2025. Jump in to find out her research focus and conference tips!
November 26, 2025 at 6:27 AM
Today we have Brenda Schulman, Director of the Department of Molecular Machines and Signalling at Max Planck Institute of Biochemistry, as our interviewee at #AusUb2025. Jump in to find out her research focus and conference tips!
Reposted by Komander Lab
‼️Have a listen to a little about Kylie Walter’s exciting new research, conference talk, and her experience at #AusUb2025. What did she enjoy most about the conference?
More interviews to come in the next week so stay tuned 😁
More interviews to come in the next week so stay tuned 😁
December 9, 2025 at 5:08 AM
‼️Have a listen to a little about Kylie Walter’s exciting new research, conference talk, and her experience at #AusUb2025. What did she enjoy most about the conference?
More interviews to come in the next week so stay tuned 😁
More interviews to come in the next week so stay tuned 😁
Reposted by Komander Lab
‼️It was wonderful to have Professor Kay Hoffmann at the #AusUb25 - and even better to get the chance to interview him! Hear about his experiences in industry and academia as well as his love for proteins😁
December 11, 2025 at 2:37 AM
‼️It was wonderful to have Professor Kay Hoffmann at the #AusUb25 - and even better to get the chance to interview him! Hear about his experiences in industry and academia as well as his love for proteins😁
Reposted by Komander Lab
‼️ Following on from our “M1 chains everywhere!” session at #AusUb25 we took the chance to interview one of the pioneering researchers in this field, Kazuhiro Iwai. Have a look below! ✨✨✨
December 13, 2025 at 8:31 AM
‼️ Following on from our “M1 chains everywhere!” session at #AusUb25 we took the chance to interview one of the pioneering researchers in this field, Kazuhiro Iwai. Have a look below! ✨✨✨
Reposted by Komander Lab
‼️Towards the end of #AusUb25, we caught up with Jonathan Pruneda to discuss ubiquitin signalling and its relationship with host-pathogen interactions. It was an amazing conference and such a great chance to meet people from across the ubiquitin field 🤩
December 17, 2025 at 4:20 AM
‼️Towards the end of #AusUb25, we caught up with Jonathan Pruneda to discuss ubiquitin signalling and its relationship with host-pathogen interactions. It was an amazing conference and such a great chance to meet people from across the ubiquitin field 🤩
Reposted by Komander Lab
‼️For our final invited speaker interview, we talked with the amazing Titia Sixma about her work on the role of ubiquitin in DNA regulation, and some #AusUb2025 highlights. Thank you to everyone who came, it was an amazing conference and a great chance to see the breadth of global ubiquitin research!
December 20, 2025 at 10:53 AM
‼️For our final invited speaker interview, we talked with the amazing Titia Sixma about her work on the role of ubiquitin in DNA regulation, and some #AusUb2025 highlights. Thank you to everyone who came, it was an amazing conference and a great chance to see the breadth of global ubiquitin research!
Reposted by Komander Lab
Is there any biomolecule thats not #Ubiquitinated ? 🫣
It was super fun to chair my fav session on 'Ubiquitinating EVERYthing' during the kickstart event of #AusUb2025
It was super fun to chair my fav session on 'Ubiquitinating EVERYthing' during the kickstart event of #AusUb2025
#AusUb25 kicked off with an amazing session on ‘Ubiquitinating Things’. Thank you to all speakers: Brenda Schulman, Jonathan Pruneda, Satpal Virdee, Andrii Gorelik, and Yukiko Yoshida!
November 21, 2025 at 12:47 AM
Is there any biomolecule thats not #Ubiquitinated ? 🫣
It was super fun to chair my fav session on 'Ubiquitinating EVERYthing' during the kickstart event of #AusUb2025
It was super fun to chair my fav session on 'Ubiquitinating EVERYthing' during the kickstart event of #AusUb2025
Reposted by Komander Lab
Today is the day! The Inaugural Australian Ubiquitin Summit #AusUb2025 was officially opened by committee chair David Komander.
November 20, 2025 at 5:02 AM
Today is the day! The Inaugural Australian Ubiquitin Summit #AusUb2025 was officially opened by committee chair David Komander.
Really excited for the first Australian Ubiquitin Summit starting tomorrow!
Some of us got an early start at ISA11 Lorne. Awesome presentations from @simoncobb.bsky.social, Laura Fielden and @sylviecallegari.bsky.social
See you in Lorne!
@ausub.bsky.social
Some of us got an early start at ISA11 Lorne. Awesome presentations from @simoncobb.bsky.social, Laura Fielden and @sylviecallegari.bsky.social
See you in Lorne!
@ausub.bsky.social
November 19, 2025 at 3:10 AM
Really excited for the first Australian Ubiquitin Summit starting tomorrow!
Some of us got an early start at ISA11 Lorne. Awesome presentations from @simoncobb.bsky.social, Laura Fielden and @sylviecallegari.bsky.social
See you in Lorne!
@ausub.bsky.social
Some of us got an early start at ISA11 Lorne. Awesome presentations from @simoncobb.bsky.social, Laura Fielden and @sylviecallegari.bsky.social
See you in Lorne!
@ausub.bsky.social
Reposted by Komander Lab
⏳Four days to go until #AusUb2025! Check out the video below to hear some conference tips and tricks from our committee chair David Komander (and some potentially controversial interest rankings!?!?).
More interviews to come in the next few days so watch this space 😉
More interviews to come in the next few days so watch this space 😉
November 16, 2025 at 12:25 PM
⏳Four days to go until #AusUb2025! Check out the video below to hear some conference tips and tricks from our committee chair David Komander (and some potentially controversial interest rankings!?!?).
More interviews to come in the next few days so watch this space 😉
More interviews to come in the next few days so watch this space 😉
Reposted by Komander Lab
Stay tuned for some ✨exclusive✨ interviews from our organising committee members (including committee chair David Komander!).
November 14, 2025 at 11:16 AM
Stay tuned for some ✨exclusive✨ interviews from our organising committee members (including committee chair David Komander!).
Looking forward to seeing everyone in Lorne!! Only three weeks to go!
📢 All ubiquitin aficionados! 📢
We are gearing up for the first Australian Ubiquitin Summit in three weeks 🤩🗓️
Are you ready for talking ubiquitin by the bay?
🗓️ 20-23 Nov
📍Mantra, Lorne, VIC
Chaired by David Komander (@komanderlab.bsky.social)
#AusUb2025
We are gearing up for the first Australian Ubiquitin Summit in three weeks 🤩🗓️
Are you ready for talking ubiquitin by the bay?
🗓️ 20-23 Nov
📍Mantra, Lorne, VIC
Chaired by David Komander (@komanderlab.bsky.social)
#AusUb2025
October 31, 2025 at 12:37 PM
Looking forward to seeing everyone in Lorne!! Only three weeks to go!
Reposted by Komander Lab
Very exciting to see the @wehi-research.bsky.social PINK1 Parkinson’s Disease research team win the Eureka Prize for Scientific Research. Amazing achievement by a brilliant team! @eurekaprizes.bsky.social
September 3, 2025 at 10:00 AM
Very exciting to see the @wehi-research.bsky.social PINK1 Parkinson’s Disease research team win the Eureka Prize for Scientific Research. Amazing achievement by a brilliant team! @eurekaprizes.bsky.social
Reposted by Komander Lab
🎉 What an honour to be a finalist in the 2025 Australian Museum Eureka Prizes for Scientific Discovery!! With David Komander, @zhongyangan.bsky.social, Alisa Glukhova and @nskirk.bsky.social.
Excited for the awards ceremony on Sept 3rd!
@eurekaprizes.bsky.social
@wehi-research.bsky.social
Excited for the awards ceremony on Sept 3rd!
@eurekaprizes.bsky.social
@wehi-research.bsky.social
PINK1 Parkinson's Disease Research Team – Finalist, 2025 Eureka Prize for Scientific Research
YouTube video by Australian Museum
www.youtube.com
July 31, 2025 at 12:00 AM
🎉 What an honour to be a finalist in the 2025 Australian Museum Eureka Prizes for Scientific Discovery!! With David Komander, @zhongyangan.bsky.social, Alisa Glukhova and @nskirk.bsky.social.
Excited for the awards ceremony on Sept 3rd!
@eurekaprizes.bsky.social
@wehi-research.bsky.social
Excited for the awards ceremony on Sept 3rd!
@eurekaprizes.bsky.social
@wehi-research.bsky.social
📣📣 Abstract deadline extension to Friday 1st August 📣📣
If you missed the last deadline, then don't miss out again!! Join us for sun, surf and ubiquitin in November at Lorne, Australia.
If you missed the last deadline, then don't miss out again!! Join us for sun, surf and ubiquitin in November at Lorne, Australia.
July 28, 2025 at 10:40 AM
📣📣 Abstract deadline extension to Friday 1st August 📣📣
If you missed the last deadline, then don't miss out again!! Join us for sun, surf and ubiquitin in November at Lorne, Australia.
If you missed the last deadline, then don't miss out again!! Join us for sun, surf and ubiquitin in November at Lorne, Australia.
Grateful for the support from the Parkinson's Research Foundation!
WEHI has formed a partnership with the Parkinson’s Research Foundation with one clear goal: to intensify the search for drug treatments to stop Parkinson’s.
Read more👇 www.wehi.edu.au/news/new-par...
Read more👇 www.wehi.edu.au/news/new-par...
New partnership with Parkinson’s Research Foundation to accelerate Parkinson’s drug discovery
WEHI has formed a partnership with the Parkinson’s Research Foundation with one clear goal: to intensify the search for drug treatments to stop Parkinson’s.
www.wehi.edu.au
July 17, 2025 at 3:24 AM
Grateful for the support from the Parkinson's Research Foundation!
📣 Calling all ubiquitin aficionados - one week to go before abstract deadline (July 18th)!! Join us on the coast in Lorne, Australia. www.lorneubiquitin.org
#ubiquitin
#ubiquitin
July 11, 2025 at 7:08 AM
📣 Calling all ubiquitin aficionados - one week to go before abstract deadline (July 18th)!! Join us on the coast in Lorne, Australia. www.lorneubiquitin.org
#ubiquitin
#ubiquitin
Two weeks to go before the abstract deadline (July 18th)! Looking forward to seeing you all there!
Australia’s First Ubiquitin Summit is here! 🥳
📍Lorne, Victoria | 🗓️ 20–23 November 2025
Join us on the scenic coastline of Lorne for 4 days of cutting-edge ubiquitin science, featuring a fantastic lineup of international speakers covering all corners of the Ub world—from mechanisms to therapeutics
📍Lorne, Victoria | 🗓️ 20–23 November 2025
Join us on the scenic coastline of Lorne for 4 days of cutting-edge ubiquitin science, featuring a fantastic lineup of international speakers covering all corners of the Ub world—from mechanisms to therapeutics
July 4, 2025 at 1:42 PM
Two weeks to go before the abstract deadline (July 18th)! Looking forward to seeing you all there!
Reposted by Komander Lab
Excited to share our latest work, now out in @lsajournal.org. we show that the E3 ligase HOIL-1 can ubiquitinate many different saccharides and describe a chemoenzymatic platform to generate ubiquitinated sugars as tools for studying non-proteinaceous ubiquitination.
The RBR E3 ligase HOIL-1 ubiquitinates Ser/Thr-residues and various disaccharides in vitro and can be used to generate ubiquitinated sugars as tools to study non-proteinaceous ubiquitination
@lechtenberglab.bsky.social @wehi-research.bsky.social
www.life-science-alliance.org/content/8/6/...
@lechtenberglab.bsky.social @wehi-research.bsky.social
www.life-science-alliance.org/content/8/6/...
April 10, 2025 at 7:49 AM
Excited to share our latest work, now out in @lsajournal.org. we show that the E3 ligase HOIL-1 can ubiquitinate many different saccharides and describe a chemoenzymatic platform to generate ubiquitinated sugars as tools for studying non-proteinaceous ubiquitination.
Reposted by Komander Lab
Could this breakthrough research lead to the first treatment for #longCOVID? A world-first milestone made possible through the advanced technologies of the National Drug Discovery Centre.
Find out more: www.wehi.edu.au/news/tacklin...
Find out more: www.wehi.edu.au/news/tacklin...
April 8, 2025 at 11:53 PM
Could this breakthrough research lead to the first treatment for #longCOVID? A world-first milestone made possible through the advanced technologies of the National Drug Discovery Centre.
Find out more: www.wehi.edu.au/news/tacklin...
Find out more: www.wehi.edu.au/news/tacklin...
Excited to share news from the lab out in Nature Communications – A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID
www.nature.com/articles/s41...
@wehi-research.bsky.social
www.nature.com/articles/s41...
@wehi-research.bsky.social
A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID - Nature Communications
A novel antiviral targeting the SARS-CoV-2 PLpro protease shows strong efficacy in a mouse model, preventing lung pathology and reducing brain dysfunction. The study provides proof-of-principle that P...
www.nature.com
April 8, 2025 at 10:30 PM
Excited to share news from the lab out in Nature Communications – A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID
www.nature.com/articles/s41...
@wehi-research.bsky.social
www.nature.com/articles/s41...
@wehi-research.bsky.social
Join us at the beach for the first Australian Ubiquitin summit from 20-23 Nov! 🏄♀️ Check out the amazing speakers here: www.lorneubiquitin.org
And, why not stay a little longer and join the International Symposium on Autophagy from 16-20 Nov, also in beautiful Lorne ☀️. www.isa11.org
See you there!
And, why not stay a little longer and join the International Symposium on Autophagy from 16-20 Nov, also in beautiful Lorne ☀️. www.isa11.org
See you there!
April 7, 2025 at 10:10 AM
Join us at the beach for the first Australian Ubiquitin summit from 20-23 Nov! 🏄♀️ Check out the amazing speakers here: www.lorneubiquitin.org
And, why not stay a little longer and join the International Symposium on Autophagy from 16-20 Nov, also in beautiful Lorne ☀️. www.isa11.org
See you there!
And, why not stay a little longer and join the International Symposium on Autophagy from 16-20 Nov, also in beautiful Lorne ☀️. www.isa11.org
See you there!