Karla Satchell
@karlasatchell.bsky.social
Northwestern University Microbiology Professor studying Vibrio toxins, Structural Biology, COVID and RAS degraders. Supporting women as leaders in Science.
The annual news blitz about danger this time year of Vibrio vulnificus is upon us. If you live in the Gulf or Atlantic areas, and particularly if you have liver disease, cancer, or immunosuppression, Vv is a danger. The disease is rare but death rates high, survivors have long hospitalizations 🧵
How to protect yourself from Vibrio vulnificus, the bacteria found in some coastal waters
States are warning beachgoers about a summertime surge in infections from a frightening, flesh-eating bacteria found in coastal waters.
apnews.com
August 25, 2025 at 6:20 PM
The annual news blitz about danger this time year of Vibrio vulnificus is upon us. If you live in the Gulf or Atlantic areas, and particularly if you have liver disease, cancer, or immunosuppression, Vv is a danger. The disease is rare but death rates high, survivors have long hospitalizations 🧵
Great time with my awesome Northwestern colleagues at #GRCMAST
Northwestern Micro representing at the 2025GRC MAST conference in beautiful Newport. Great science, collegial people but there’s a cloud hanging over us all. ☁️
July 25, 2025 at 4:16 AM
Great time with my awesome Northwestern colleagues at #GRCMAST
Reposted by Karla Satchell
Congratulations to Mason Clark who won the @fems MicroLife poster prize at the Microbial Adhesion and Signal Transduction GRC!
July 25, 2025 at 2:47 AM
Congratulations to Mason Clark who won the @fems MicroLife poster prize at the Microbial Adhesion and Signal Transduction GRC!
Reposted by Karla Satchell
Northwestern Micro representing at the 2025GRC MAST conference in beautiful Newport. Great science, collegial people but there’s a cloud hanging over us all. ☁️
July 24, 2025 at 7:39 PM
Northwestern Micro representing at the 2025GRC MAST conference in beautiful Newport. Great science, collegial people but there’s a cloud hanging over us all. ☁️
Reposted by Karla Satchell
“NIH will introduce a cap on allowable publication costs starting in Fiscal Year (FY) 2026, ensuring that publication fees remain reasonable across the research ecosystem. The policy aims to curb excessive APCs & ensure the broad dissemination of research findings w/o unnecessary financial barriers”
An actual good thing coming from this NIH nightmare? www.nih.gov/news-events/...
July 9, 2025 at 2:02 PM
“NIH will introduce a cap on allowable publication costs starting in Fiscal Year (FY) 2026, ensuring that publication fees remain reasonable across the research ecosystem. The policy aims to curb excessive APCs & ensure the broad dissemination of research findings w/o unnecessary financial barriers”
Reposted by Karla Satchell
This is an event on Tuesday in the House of Representatives hosted by the minority Science committee, led by @lofgren.house.gov.
Real question: why isn’t this being held in the evening and produced for TV and social media?
There are production and storytelling resources in Congress.
Real question: why isn’t this being held in the evening and produced for TV and social media?
There are production and storytelling resources in Congress.
Science 🧪 fair of knowledge lost due to grant terminations. Why isn’t this being live-streamed? How do we - the people - get to watch?
nasawatch.com/congress/con...
nasawatch.com/congress/con...
Congressional Event: A Science Fair of Canceled Grants
The Things We’ll Never Know: A Science Fair of Canceled Grants.
nasawatch.com
July 7, 2025 at 3:42 PM
This is an event on Tuesday in the House of Representatives hosted by the minority Science committee, led by @lofgren.house.gov.
Real question: why isn’t this being held in the evening and produced for TV and social media?
There are production and storytelling resources in Congress.
Real question: why isn’t this being held in the evening and produced for TV and social media?
There are production and storytelling resources in Congress.
Reposted by Karla Satchell
"A document [DHHS] sent to lawmakers to support Secretary Robert F. Kennedy Jr.’s decision to change U.S. policy on covid vaccines cites scientific studies that are unpublished or under dispute and mischaracterizes others."
kffhealthnews.org/news/article... via @kffhealthnews.org
kffhealthnews.org/news/article... via @kffhealthnews.org
Kennedy’s HHS Sent Congress ‘Junk Science’ To Defend Vaccine Changes, Experts Say - KFF Health News
A look inside the Department of Health and Human Services document citing vaccine misinformation that could influence congressional perceptions.
kffhealthnews.org
June 15, 2025 at 4:54 PM
"A document [DHHS] sent to lawmakers to support Secretary Robert F. Kennedy Jr.’s decision to change U.S. policy on covid vaccines cites scientific studies that are unpublished or under dispute and mischaracterizes others."
kffhealthnews.org/news/article... via @kffhealthnews.org
kffhealthnews.org/news/article... via @kffhealthnews.org
Reposted by Karla Satchell
RFK Jr's "MAHA" report is filled with references to studies that literally do not exist, or that completely misinterpret the studies' findings.
“We did not publish a paper.. on this topic with that co-author group, or with that title,” says one cited researcher.
www.notus.org/health-scien...
“We did not publish a paper.. on this topic with that co-author group, or with that title,” says one cited researcher.
www.notus.org/health-scien...
The MAHA Report Cites Studies That Don’t Exist
The Trump administration’s “Make America Healthy Again” report misinterprets some studies and cites others that don’t exist, according to the listed authors.
www.notus.org
May 29, 2025 at 12:35 PM
RFK Jr's "MAHA" report is filled with references to studies that literally do not exist, or that completely misinterpret the studies' findings.
“We did not publish a paper.. on this topic with that co-author group, or with that title,” says one cited researcher.
www.notus.org/health-scien...
“We did not publish a paper.. on this topic with that co-author group, or with that title,” says one cited researcher.
www.notus.org/health-scien...
Thanks to Northwestern Feinberg communications for writing this nice article on our recent work for the newsletter. @vibrio-vulnificus.bsky.social
Scientists led by @karlasatchell.bsky.social have discovered previously unknown molecular mechanisms that help a type of foodborne bacteria, Vibrio vulnificus, recognize host cells and initiate infection, according to a recent study in Science Advances. @jiexic.bsky.social
tinyurl.com/mtu457fj
tinyurl.com/mtu457fj
Novel Mechanisms Help Lethal Bacteria Recognize and Infect Cells - News Center
Scientists led by Karla Satchell, PhD, have discovered previously unknown molecular mechanisms that help a type of foodborne bacteria called Vibrio vulnificus recognize host cells and initiate infecti...
tinyurl.com
May 11, 2025 at 10:23 PM
Thanks to Northwestern Feinberg communications for writing this nice article on our recent work for the newsletter. @vibrio-vulnificus.bsky.social
Great new study by my excellent colleague @jutraslab.bsky.social on treatments for Luke’s disease
After screening nearly 500 FDA approved compounds, researchers have settled on piperacillin as a good candidate for clearing the bacteria that cause Lyme disease. B. burgdoferi is known for lingering in some patients causing post-treatment Lyme disease syndrome, also called chronic Lyme 👇
Antibiotic Candidate for Lyme Disease Boosts Hope for Custom Approach
Researchers also put forth one explanation for chronic symptoms after treatment
www.medpagetoday.com
April 28, 2025 at 12:07 PM
Great new study by my excellent colleague @jutraslab.bsky.social on treatments for Luke’s disease
Reposted by Karla Satchell
To say it once more today: I think you'll be moved if you take 2 minutes to look through 269 institutions signed on here.
Yes, still a few notable absences. (Where is Stanford?) But such an array of *presence.* Big and small. Public and private. World famous and barely known. Check them out.
Yes, still a few notable absences. (Where is Stanford?) But such an array of *presence.* Big and small. Public and private. World famous and barely known. Check them out.
Now it's nearly 270 university presidents who have signed onto this "unprecedented government overreach" public letter. It was less than 180 this morning.
www.aacu.org/newsroom/a-c...
Universities, and judges, taking the lead in standing up.
www.aacu.org/newsroom/a-c...
Universities, and judges, taking the lead in standing up.
April 23, 2025 at 4:58 AM
To say it once more today: I think you'll be moved if you take 2 minutes to look through 269 institutions signed on here.
Yes, still a few notable absences. (Where is Stanford?) But such an array of *presence.* Big and small. Public and private. World famous and barely known. Check them out.
Yes, still a few notable absences. (Where is Stanford?) But such an array of *presence.* Big and small. Public and private. World famous and barely known. Check them out.
Graduate student Jiexi Chen presented today in the emerging scientist session #ASBMB25 on her new paper on toxin binding N-glycans. She did a great job!!
April 12, 2025 at 11:20 PM
Graduate student Jiexi Chen presented today in the emerging scientist session #ASBMB25 on her new paper on toxin binding N-glycans. She did a great job!!
Taking a break from the news in Bsky. Happy to share amazing study by student Jiexi Chen on Vibrio vulnificus MARTX toxin engagement of N-glycans and receptor L1CAM. First study on this toxin binding to cell surfaces. #vibrio #microsky #toxins www.science.org/doi/10.1126/...
Vibrio MARTX toxin binding of biantennary N-glycans at host cell surfaces
The large pore-forming toxin MARTX with broad tissue tropism binds the essential unit of N-glycans on eukaryotic cell membranes.
www.science.org
April 11, 2025 at 12:12 PM
Taking a break from the news in Bsky. Happy to share amazing study by student Jiexi Chen on Vibrio vulnificus MARTX toxin engagement of N-glycans and receptor L1CAM. First study on this toxin binding to cell surfaces. #vibrio #microsky #toxins www.science.org/doi/10.1126/...
Was great to participate in this project designed to test robustness of AI ligand prediction but had a side benefit of crowd-sourced discovery of a SARS-CoV-2 helicase inhibitor
...and kudo to Karina Machado and @dkoes.compstruct.org for their winning predictions and to @karlasatchell.bsky.social for the unwinding assays!
The CACHE #2 preprint is now online: bit.ly/3DyCmHN Active learning and fragment growing delivered confirmed hits. A citizen scientist using the Fold-it gaming interface designed the top compound! Kudos to Sasha and Madhushika @thesgc.bsky.social at the bench. @conscience-network.bsky.social
March 11, 2025 at 12:00 AM
Was great to participate in this project designed to test robustness of AI ligand prediction but had a side benefit of crowd-sourced discovery of a SARS-CoV-2 helicase inhibitor
Reposted by Karla Satchell
Slashing IRS staff will end up costing the U.S. government.
Multiple studies have shown that for every dollar spent by the IRS, the agency returns between $5 and $12.
New @propublica.org by @andykroll.bsky.social
Multiple studies have shown that for every dollar spent by the IRS, the agency returns between $5 and $12.
New @propublica.org by @andykroll.bsky.social
How DOGE’s Cuts to the IRS Threaten to Cost More Than DOGE Will Ever Save
The Trump administration claims gutting federal agencies will save money, but cutting the IRS means the government collects less taxes. “If you’re interested in the deficit and curbing it, why would y...
www.propublica.org
March 5, 2025 at 11:25 AM
Slashing IRS staff will end up costing the U.S. government.
Multiple studies have shown that for every dollar spent by the IRS, the agency returns between $5 and $12.
New @propublica.org by @andykroll.bsky.social
Multiple studies have shown that for every dollar spent by the IRS, the agency returns between $5 and $12.
New @propublica.org by @andykroll.bsky.social
Wonderful recognition! Hank gave great speech at ceremony on how service and faculty joining together is most important in challenging times
Congratulations to H. Steven (Hank) Seifert, PhD, on receiving Northwestern’s 2025 Provost Award for Exemplary Faculty Service! This annual honor recognizes outstanding service and academic citizenship. @gcrox.bsky.social
bit.ly/3XlaJZc
bit.ly/3XlaJZc
March 4, 2025 at 4:57 PM
Wonderful recognition! Hank gave great speech at ceremony on how service and faculty joining together is most important in challenging times
Reposted by Karla Satchell
Reposted by Karla Satchell
🗽🔬 STAND UP FOR SCIENCE. Chicago joins the nationwide movement to demand that our government fully support scientific research, which employs people, benefits our economy, and SAVES LIVES
Join Indivisible Chicago & @standupforscience.bsky.social on Fri, March 7th, 12pm, Federal Plaza. Info/Sign-up:
Join Indivisible Chicago & @standupforscience.bsky.social on Fri, March 7th, 12pm, Federal Plaza. Info/Sign-up:
Stand up for Science · Indivisible Chicago
Science is for everyone–and benefits everyone.
When the federal government supports scientific research through taxpayer funding, it fuels innovation, creates jobs, and sustains the
world we live in...
www.mobilize.us
February 26, 2025 at 4:00 PM
🗽🔬 STAND UP FOR SCIENCE. Chicago joins the nationwide movement to demand that our government fully support scientific research, which employs people, benefits our economy, and SAVES LIVES
Join Indivisible Chicago & @standupforscience.bsky.social on Fri, March 7th, 12pm, Federal Plaza. Info/Sign-up:
Join Indivisible Chicago & @standupforscience.bsky.social on Fri, March 7th, 12pm, Federal Plaza. Info/Sign-up:
Reposted by Karla Satchell
It’s impossible to overstate how much damage Trump/Elon/Vought/RFKJ are doing to science in America.
We need everyone who can to show up and demand action to save scientific research in this country.
Scientists are trained to question everything which is why fascists always target them first.
We need everyone who can to show up and demand action to save scientific research in this country.
Scientists are trained to question everything which is why fascists always target them first.
WHERE WILL YOU BE ON MARCH 7TH!?
Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one!
#standupforscience2025
Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one!
#standupforscience2025
March 2, 2025 at 4:15 PM
It’s impossible to overstate how much damage Trump/Elon/Vought/RFKJ are doing to science in America.
We need everyone who can to show up and demand action to save scientific research in this country.
Scientists are trained to question everything which is why fascists always target them first.
We need everyone who can to show up and demand action to save scientific research in this country.
Scientists are trained to question everything which is why fascists always target them first.
Reposted by Karla Satchell
This is a crisis threatening the US scientific research enterprise which drives our wealth, health and prosperity. Make that clear to anyone and everyone you know
The NIH funding freeze has blocked 3 of our grant proposals (so far), which threatens to shut down our Lyme disease research program within a year.
🦠🧫🧪🧬🔬 #MicroSky
www.reuters.com/business/hea...
🦠🧫🧪🧬🔬 #MicroSky
www.reuters.com/business/hea...
Trump administration loophole snags US research grants from Lyme to lung disease
The Trump administration has for weeks been blocking the U.S. National Institutes of Health process for issuing new research grants for everything from Lyme disease to lung and heart disease, according to researchers, a departing NIH official and documents.
www.reuters.com
February 27, 2025 at 12:52 AM
This is a crisis threatening the US scientific research enterprise which drives our wealth, health and prosperity. Make that clear to anyone and everyone you know
Reposted by Karla Satchell
Elon Musk said DOGE made a mistake by cutting USAID’s Ebola prevention but it had been “restored.”
That’s not true, current and former officials told me and @johnphudson.bsky.social.
“There have been no efforts to ‘turn on’” Ebola prevention, said Nidhi Bouri, who oversaw team until January.
That’s not true, current and former officials told me and @johnphudson.bsky.social.
“There have been no efforts to ‘turn on’” Ebola prevention, said Nidhi Bouri, who oversaw team until January.
Musk claims DOGE ‘restored’ Ebola prevention effort. Officials disagree.
USAID’s initiatives to fight Ebola and other diseases have been gutted, current and former agency officials said.
www.washingtonpost.com
February 26, 2025 at 11:41 PM
Elon Musk said DOGE made a mistake by cutting USAID’s Ebola prevention but it had been “restored.”
That’s not true, current and former officials told me and @johnphudson.bsky.social.
“There have been no efforts to ‘turn on’” Ebola prevention, said Nidhi Bouri, who oversaw team until January.
That’s not true, current and former officials told me and @johnphudson.bsky.social.
“There have been no efforts to ‘turn on’” Ebola prevention, said Nidhi Bouri, who oversaw team until January.
I am going to join the Stand Up for Science in DC! Friends DM if will be there too. Chicago folks, will be missing you at Federal square #standupforscience2025
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
February 27, 2025 at 1:01 AM
I am going to join the Stand Up for Science in DC! Friends DM if will be there too. Chicago folks, will be missing you at Federal square #standupforscience2025
Reposted by Karla Satchell
Gregg is a former Marine and Forest Service ranger. He's saved the lives of hikers dangling off a cliff or going through cardiac arrest, and he's bravely fought forest fires to save small rural towns.
100% of his salary is paid by WA state.
Elon fired him. Share his story.
100% of his salary is paid by WA state.
Elon fired him. Share his story.
February 23, 2025 at 6:35 PM
Gregg is a former Marine and Forest Service ranger. He's saved the lives of hikers dangling off a cliff or going through cardiac arrest, and he's bravely fought forest fires to save small rural towns.
100% of his salary is paid by WA state.
Elon fired him. Share his story.
100% of his salary is paid by WA state.
Elon fired him. Share his story.
Reposted by Karla Satchell
Reposted by Karla Satchell
With measles flaring up and threatening to become a significant concern and H5N1 knocking on the door, today seems like a perfect day to fire all the fellows and postdocs working at the CDC
WTAF?!
WTAF?!
February 14, 2025 at 8:21 PM
With measles flaring up and threatening to become a significant concern and H5N1 knocking on the door, today seems like a perfect day to fire all the fellows and postdocs working at the CDC
WTAF?!
WTAF?!