Karla Satchell
@karlasatchell.bsky.social
Northwestern University Microbiology Professor studying Vibrio toxins, Structural Biology, COVID and RAS degraders. Supporting women as leaders in Science.
Finally, I want to inform readers that my lab has been at the forefront for >15 years on understanding how these bacteria cause disease. However, we are struggling because, as a Northwestern Faculty member, my grants to study these infections have been frozen since March. Please Support Science!
August 25, 2025 at 6:20 PM
Finally, I want to inform readers that my lab has been at the forefront for >15 years on understanding how these bacteria cause disease. However, we are struggling because, as a Northwestern Faculty member, my grants to study these infections have been frozen since March. Please Support Science!
Studies from my group have shown that Vibrio vulnficus bacteria from around the phylogenetic tree can cause infections in humans. So there are not good Vv and bad Vv...they are all bad. Just some may be much worse.
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Genetic Divergence of Vibrio vulnificus Clinical Isolates with Mild to Severe Outcomes | mBio
Vibrio vulnificus is an aquatic pathogen that is capable of causing severe disease in humans. Previous
studies have suggested that pathogenic isolates were restricted to certain phylogenetic
lineages ...
journals.asm.org
August 25, 2025 at 6:20 PM
Studies from my group have shown that Vibrio vulnficus bacteria from around the phylogenetic tree can cause infections in humans. So there are not good Vv and bad Vv...they are all bad. Just some may be much worse.
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Vibrio vulnificus is also the leading cause of seafood-borne death. I love oysters...I recommend po' boys with fried oysters, grilled, and stews. But always cooked, especially in the warm months of the year. Shrimp and other seafood also can be sources of infection. journals.lww.com/ajg/fulltext...
S3249 A Deadly Case of Vibrio vulnificus Bacteremia After... : Official journal of the American College of Gastroenterology | ACG
An abstract is unavailable.
journals.lww.com
August 25, 2025 at 6:20 PM
Vibrio vulnificus is also the leading cause of seafood-borne death. I love oysters...I recommend po' boys with fried oysters, grilled, and stews. But always cooked, especially in the warm months of the year. Shrimp and other seafood also can be sources of infection. journals.lww.com/ajg/fulltext...
Caution should be taken when walking in brackish waters and swimming. Common clinical cases include cuts while fishing, walking in shallow waters with small cuts on feet, and this one of infection while swimming with a new tattoo. casereports.bmj.com/content/2017...
Vibrio vulnificus septic shock due to a contaminated tattoo
We present a case of Vibrio vulnificus septic shock and cellulitis in a patient with chronic liver disease that occurred after obtaining a leg tattoo with subsequent seawater exposure in the Gulf of Mexico. Initial suspicion for V. vulnificus was high and he was started on empiric doxycycline and ceftriaxone at admission. Blood and wound cultures grew oxidase positive and comma-shaped Gram-negative rods ultimately confirmed to be V. vulnificus. Despite aggressive initial treatment, the patient developed septic shock and died. This case highlights the association of chronic liver disease and high mortality associated with infections of V. vulnificus . Health providers should remain vigilant for V. vulnificus infections in patients with chronic liver disease and raw oyster ingestion or seawater exposure.
casereports.bmj.com
August 25, 2025 at 6:20 PM
Caution should be taken when walking in brackish waters and swimming. Common clinical cases include cuts while fishing, walking in shallow waters with small cuts on feet, and this one of infection while swimming with a new tattoo. casereports.bmj.com/content/2017...
Hi @schakowsky.house.gov The weather is supposed to be nice for @standupforscience.bsky.social Rally for Science on the National mall. I am coming from Evanston, hope to see my rep there too!!
March 6, 2025 at 12:00 AM
Hi @schakowsky.house.gov The weather is supposed to be nice for @standupforscience.bsky.social Rally for Science on the National mall. I am coming from Evanston, hope to see my rep there too!!
They can use AI bots on their side to save time/cost to replace editors, and now trying to normalize this behavior to get reviewers to volunteer more often so they can grow revenue.
March 5, 2025 at 1:02 PM
They can use AI bots on their side to save time/cost to replace editors, and now trying to normalize this behavior to get reviewers to volunteer more often so they can grow revenue.
Nature is responding to a critical flaw in their business model, they need to grow revenue to keep billionaire investors on board, but depend on volunteer peer reviewers.
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March 5, 2025 at 1:02 PM
Nature is responding to a critical flaw in their business model, they need to grow revenue to keep billionaire investors on board, but depend on volunteer peer reviewers.
1/n
1/n