Champi
@jpascualanaya.bsky.social
Evo-devo researcher at the University of Málaga, Spain. Barça fanatic. Sparrows lover. Beer drinker. Cheese and salmon eater. Warhammer gamer and painter. 🇪🇸🇯🇵
Pinned
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
October 30, 2025 at 5:50 PM
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
Reposted by Champi
We are thrilled to share our new preprint entitled “The origin and molecular evolution of the mammalian liver cell architecture” www.biorxiv.org/content/10.1...
October 15, 2025 at 12:51 PM
We are thrilled to share our new preprint entitled “The origin and molecular evolution of the mammalian liver cell architecture” www.biorxiv.org/content/10.1...
Reposted by Champi
Did transposable elements shape brain evolution — and if so, which ones, and in which cell states and lineages? Led by @tyamadat.bsky.social, we explored this question in cerebellum development using sequence-based deep learning models!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 16, 2025 at 10:01 PM
Did transposable elements shape brain evolution — and if so, which ones, and in which cell states and lineages? Led by @tyamadat.bsky.social, we explored this question in cerebellum development using sequence-based deep learning models!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Champi
Our study on a male-essential microRNA and the evolution of other dosage compensation mechanisms in birds is now out in Nature! www.nature.com/articles/s41...
A male-essential miRNA is key for avian sex chromosome dosage compensation - Nature
Birds have evolved a unique sex chromosome dosage compensation mechanism involving the male-biased microRNA (miR-2954), which is essential for male survival by regulating the expression of dosage-sens...
www.nature.com
July 16, 2025 at 3:23 PM
Our study on a male-essential microRNA and the evolution of other dosage compensation mechanisms in birds is now out in Nature! www.nature.com/articles/s41...
Zapatero: "El PP de Andalucía tendría que hablar menos de Puigdemont y dedicarse más a la sanidad pública" www.eldiario.es/1_c121ca?utm...
Zapatero: "El PP de Andalucía tendría que hablar menos de Puigdemont y dedicarse más a la sanidad pública"
El expresidente del Gobierno ha compartido un acto con la vicepresidenta María Jesús Montero, que ha cuestionado "qué le pasa a la derecha" con las mujeres y ha cargado contra el apoyo del PP al falso...
www.eldiario.es
October 4, 2025 at 8:36 PM
Zapatero: "El PP de Andalucía tendría que hablar menos de Puigdemont y dedicarse más a la sanidad pública" www.eldiario.es/1_c121ca?utm...
Reposted by Champi
La UEFA abordará la expulsión de los equipos israelíes de sus competiciones la semana que viene
La UEFA abordará la expulsión de los equipos israelíes de sus competiciones la semana que viene
La mayoría de los países miembros del organismo que rige el fútbol europeo estarían a favor de suspender a los equipos israelíes, según el medio británico 'The Times'
www.eldiario.es
September 25, 2025 at 2:09 PM
La UEFA abordará la expulsión de los equipos israelíes de sus competiciones la semana que viene
Reposted by Champi
In case you've ever wondered, I talked with @amjeve.bsky.social about science, myself, and the future of #DevBio as part of the Pathway to Independence Fellowship @biologists.bsky.social 🧪 journals.biologists.com/dev/article/...
Pathway to Independence – an interview with Joaquín Navajas Acedo
Joaquín Navajas Acedo is a Postdoc in the lab of Dr Alexander Schier in Biozentrum at the University of Basel, Switzerland. He is interested in how the nervous system evolves and develops at the singl...
journals.biologists.com
August 5, 2025 at 10:54 AM
In case you've ever wondered, I talked with @amjeve.bsky.social about science, myself, and the future of #DevBio as part of the Pathway to Independence Fellowship @biologists.bsky.social 🧪 journals.biologists.com/dev/article/...
Reposted by Champi
Tardigrades tardigrades tardigrades
New preprint from @morielab.bsky.social: tardigrades are super resistant to DNA insult, yet are not immortal. We asked: why & how do they die? We have discovered their Achilles’ heel! Check it to know (spoiler: it has to do of course with DNA… but also lipids!! 😍)
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
August 5, 2025 at 12:56 PM
Tardigrades tardigrades tardigrades
In Japan, Anti-Establishment Parties Resonate With Young Voters www.nytimes.com/2025/07/21/w...
In Japan, Anti-Establishment Parties Resonate With Young Voters
www.nytimes.com
July 22, 2025 at 12:00 AM
In Japan, Anti-Establishment Parties Resonate With Young Voters www.nytimes.com/2025/07/21/w...
Reposted by Champi
No new genes needed to fly - just rewire what you have! 🦇🧬
Great new paper from the labs of @fany-real.bsky.social @stemundi.bsky.social @dariloops.bsky.social
doi.org/10.1038/s415...
#EvoDevo #SingleCell #BatWings
Great new paper from the labs of @fany-real.bsky.social @stemundi.bsky.social @dariloops.bsky.social
doi.org/10.1038/s415...
#EvoDevo #SingleCell #BatWings
July 16, 2025 at 1:49 PM
No new genes needed to fly - just rewire what you have! 🦇🧬
Great new paper from the labs of @fany-real.bsky.social @stemundi.bsky.social @dariloops.bsky.social
doi.org/10.1038/s415...
#EvoDevo #SingleCell #BatWings
Great new paper from the labs of @fany-real.bsky.social @stemundi.bsky.social @dariloops.bsky.social
doi.org/10.1038/s415...
#EvoDevo #SingleCell #BatWings
Reposted by Champi
Shark embryos of four different developmental stages, growing outside of their eggcases 🦈 🧪
July 16, 2025 at 1:00 PM
Shark embryos of four different developmental stages, growing outside of their eggcases 🦈 🧪
Yesterday my student Anita and I visited Tatsuya Hirasawa’s lab @utokyoofficial.bsky.social together with Wataru Takagi (AORI, Uni Tokyo). We had an afternoon full of fruitful discussions w/ everyone in his lab. Very excited by the new collaborative projects on the #hagfish we just started
July 16, 2025 at 12:45 PM
Yesterday my student Anita and I visited Tatsuya Hirasawa’s lab @utokyoofficial.bsky.social together with Wataru Takagi (AORI, Uni Tokyo). We had an afternoon full of fruitful discussions w/ everyone in his lab. Very excited by the new collaborative projects on the #hagfish we just started
Reposted by Champi
BUSCO v6.0.0 has been released. busco.ezlab.org
BUSCO - from QC to gene prediction and phylogenomics
from QC to gene prediction and phylogenomics
busco.ezlab.org
July 11, 2025 at 9:29 PM
BUSCO v6.0.0 has been released. busco.ezlab.org
Reposted by Champi
RT. Fully funded PhD position in my lab to investigate the origin, composition and function of Ambulacrarian ossicles.
June 23, 2025 at 5:28 PM
RT. Fully funded PhD position in my lab to investigate the origin, composition and function of Ambulacrarian ossicles.
Reposted by Champi
This month's ERGA BioGenome Analysis & Applications Seminar will feature a talk by speaker Pío Sierra about a new tool, pantera, which allows faster identification of Transposable Elements in genome assemblies. www.erga-biodiversity.eu/post/faster-...
Faster identification of Transposable Elements in full genome assemblies
This month's ERGA BioGenome Analysis & Applications Seminar will feature a talk by speaker Pío Sierra about a new tool, pantera, which allows faster identification of Transposable Elements in genome a...
www.erga-biodiversity.eu
July 4, 2025 at 6:35 AM
This month's ERGA BioGenome Analysis & Applications Seminar will feature a talk by speaker Pío Sierra about a new tool, pantera, which allows faster identification of Transposable Elements in genome assemblies. www.erga-biodiversity.eu/post/faster-...
Reposted by Champi
Reposted by Champi
Just noticed that Stavros has put out another 'solid' paper last month. 🔥 Impressive given what he has to deal with these days.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Solid phase transitions as a solution to the genome folding paradox - Nature
In vitro reconstitution and in vivo live-cell imaging of LHX2–EBF1–LDB1 enhancer hubs in olfactory sensory neurons reveals that these transcription factors form condensates with solid, rathe...
www.nature.com
July 3, 2025 at 4:28 AM
Just noticed that Stavros has put out another 'solid' paper last month. 🔥 Impressive given what he has to deal with these days.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Champi
Our paper describing the Range Extender element which is required and sufficient for long-range enhancer activation at the Shh locus is now available at @nature.com. Congrats to @gracebower.bsky.social who led the study. Below is a brief summary of the main findings www.nature.com/articles/s41... 1/
Range extender mediates long-distance enhancer activity - Nature
The REX element is associated with long-range enhancer–promoter interactions.
www.nature.com
July 2, 2025 at 4:17 PM
Our paper describing the Range Extender element which is required and sufficient for long-range enhancer activation at the Shh locus is now available at @nature.com. Congrats to @gracebower.bsky.social who led the study. Below is a brief summary of the main findings www.nature.com/articles/s41... 1/
Reposted by Champi
Getting the message across from a distance:
🧬REX🧬 is a “Range EXtender” element that can turn short-range into looooooooooooong-range enhancers
Great collaboration led by @gracebower.bsky.social and @evgenykvon.bsky.social
www.nature.com/articles/s41...
@biosci.lbl.gov @berkeleylab.lbl.gov
🧬REX🧬 is a “Range EXtender” element that can turn short-range into looooooooooooong-range enhancers
Great collaboration led by @gracebower.bsky.social and @evgenykvon.bsky.social
www.nature.com/articles/s41...
@biosci.lbl.gov @berkeleylab.lbl.gov
July 2, 2025 at 4:03 PM
Getting the message across from a distance:
🧬REX🧬 is a “Range EXtender” element that can turn short-range into looooooooooooong-range enhancers
Great collaboration led by @gracebower.bsky.social and @evgenykvon.bsky.social
www.nature.com/articles/s41...
@biosci.lbl.gov @berkeleylab.lbl.gov
🧬REX🧬 is a “Range EXtender” element that can turn short-range into looooooooooooong-range enhancers
Great collaboration led by @gracebower.bsky.social and @evgenykvon.bsky.social
www.nature.com/articles/s41...
@biosci.lbl.gov @berkeleylab.lbl.gov
Reposted by Champi
In our new preprint we describe the synaptic #connectome of the nerve net in the ctenophore gravisensory organ. https://www.biorxiv.org/content/10.1101/2025.06.26.661250v1 #biology #neuroscience #ctenophore #vem
June 30, 2025 at 5:51 AM
In our new preprint we describe the synaptic #connectome of the nerve net in the ctenophore gravisensory organ. https://www.biorxiv.org/content/10.1101/2025.06.26.661250v1 #biology #neuroscience #ctenophore #vem
Reposted by Champi
When you see convergent phenotypes do u wonder about their genetic basis? Did they re-invent some genetic element to construct the phenotype? The mammal placenta-a pretty important organ-has a lot of convergent phenotypes & this paper helps explain how they come about www.biorxiv.org/content/10.1...
Mammal placental phenotypes are predictable from microRNA repertoires.
Despite >100 million years of mammal diversification, similar placental morphologies have independently evolved multiple times, presenting a long-standing evolutionary puzzle: what genetic mechanisms ...
www.biorxiv.org
June 30, 2025 at 3:17 PM
When you see convergent phenotypes do u wonder about their genetic basis? Did they re-invent some genetic element to construct the phenotype? The mammal placenta-a pretty important organ-has a lot of convergent phenotypes & this paper helps explain how they come about www.biorxiv.org/content/10.1...
Always impressive to work on evo-devo questions using this wonderful animal. One more year visiting my colleagues and friends in Japan during the spawning season of the Arctic lamprey, Lethenteron camtschaticum. Thank you, Takagi-san and Sugahara-san!
July 1, 2025 at 1:13 AM
Always impressive to work on evo-devo questions using this wonderful animal. One more year visiting my colleagues and friends in Japan during the spawning season of the Arctic lamprey, Lethenteron camtschaticum. Thank you, Takagi-san and Sugahara-san!
Reposted by Champi
I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...
Chromatin loops are an ancestral hallmark of the animal regulatory genome - Nature
The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of ...
www.nature.com
May 7, 2025 at 3:23 PM
I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...
This year I'll be teaching early vertebrate evolution and basic phylogenetics analysis at the II International Summer School on Systems Biology, organized by Valeria Di Dato, @szndohrn.bsky.social
Check what's all about, and share the info with your students!
isssb2022.wixsite.com/isssystemsbi...
Check what's all about, and share the info with your students!
isssb2022.wixsite.com/isssystemsbi...
Home | ISSSB-International Summer School on Systems Biology
isssb2022.wixsite.com
June 18, 2025 at 2:28 AM
This year I'll be teaching early vertebrate evolution and basic phylogenetics analysis at the II International Summer School on Systems Biology, organized by Valeria Di Dato, @szndohrn.bsky.social
Check what's all about, and share the info with your students!
isssb2022.wixsite.com/isssystemsbi...
Check what's all about, and share the info with your students!
isssb2022.wixsite.com/isssystemsbi...
Reposted by Champi
It was a pleasure to write a N&Vs on @danielibrahim.bsky.social's latest paper in @natgenet.nature.com. Enhancers tend to stay put even if their sequence changes beyond recognition. Quoting Il Gattopardo, everything must change so that everything can stay the same: www.nature.com/articles/s41...
Genome synteny reveals hidden enhancer conservation - Nature Genetics
Enhancer sequences evolve rapidly, which has led to the prevailing view that most are not functionally conserved across species. A study now challenges this assumption by leveraging interspecies point...
www.nature.com
May 27, 2025 at 10:19 AM
It was a pleasure to write a N&Vs on @danielibrahim.bsky.social's latest paper in @natgenet.nature.com. Enhancers tend to stay put even if their sequence changes beyond recognition. Quoting Il Gattopardo, everything must change so that everything can stay the same: www.nature.com/articles/s41...