Joshua Tran
@joshuatran.bsky.social
Doctoral Candidate in the @rouxlab.bsky.social at UNIGE🇨🇭👨🔬 | @UCBerkeleyOfficial.bsky.social MCB Biochemistry Alum 🐻 | here I post science 🧪, travels ✈️, and more fun! 🤩 | views are my own
More cytoskeleton! Always beautiful to see. Another nice day doing CryoET.
November 11, 2025 at 6:50 PM
More cytoskeleton! Always beautiful to see. Another nice day doing CryoET.
Very happy today at the electron microscope! High pressure frozen budding yeast fresh off the diamond knife!
October 31, 2025 at 6:14 PM
Very happy today at the electron microscope! High pressure frozen budding yeast fresh off the diamond knife!
Reposted by Joshua Tran
I had non-Hodgkin lymphoma more than 20 years ago. Thankfully I chose chemo over coffee enemas www.bbc.co.uk/news/article...
Mum's anti-chemotherapy views influenced Paloma Shemirani's death
Paloma Shemirani died after refusing chemotherapy despite a diagnosis of non-Hodgkin lymphoma.
www.bbc.co.uk
October 2, 2025 at 3:45 PM
I had non-Hodgkin lymphoma more than 20 years ago. Thankfully I chose chemo over coffee enemas www.bbc.co.uk/news/article...
Reposted by Joshua Tran
Are the lipids associated with static protein structures there as long-lived ligands or an effect of preferential solvation? This computational-experimental framework shows the way! #lipidtime #compchem
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Molecular basis for the regulation of membrane proteins through preferential lipid solvation - Nature Chemical Biology
Static protein structures can capture the association of lipids, but it is unclear whether the association is due to lipids acting as long-lived ligands or the solvation of preferred lipids around the protein. A computational-experimental framework has now shown that for the protein CLC-ec1, it is the change in lipid solvation energies that drives dimerization, with preferred lipids around the protein modulating this driving force.
www.nature.com
September 26, 2025 at 3:29 PM
Are the lipids associated with static protein structures there as long-lived ligands or an effect of preferential solvation? This computational-experimental framework shows the way! #lipidtime #compchem
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Joshua Tran
ICYMI: This collection aims to improve the reliability and #reproducibility of studies produced by and for the cell biology community. Further articles in this series are planned and will be added to this collection when they are published. 👉 rupress.org/jcb/collecti...
September 22, 2025 at 1:31 PM
ICYMI: This collection aims to improve the reliability and #reproducibility of studies produced by and for the cell biology community. Further articles in this series are planned and will be added to this collection when they are published. 👉 rupress.org/jcb/collecti...
Reposted by Joshua Tran
Now published in @natcomms.nature.com! 🥳
👉 rdcu.be/eATn3
We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.
👉 rdcu.be/eATn3
We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.
August 15, 2025 at 12:13 PM
Now published in @natcomms.nature.com! 🥳
👉 rdcu.be/eATn3
We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.
👉 rdcu.be/eATn3
We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.
Good day doing CryoEM and escaping from the heatwave ❄️
August 14, 2025 at 6:53 PM
Good day doing CryoEM and escaping from the heatwave ❄️
Reposted by Joshua Tran
🔎New preprint!
We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture.
Big thanks to @ivanagasic.bsky.social and team!
Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5)
www.biorxiv.org/content/10.1...
We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture.
Big thanks to @ivanagasic.bsky.social and team!
Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5)
www.biorxiv.org/content/10.1...
Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability
Alpha- and beta-tubulin heterodimers dynamically assemble into microtubules, key cytoskeletal elements involved in intracellular trafficking, cell adhesion and division. The availability of free tubul...
www.biorxiv.org
July 30, 2025 at 12:20 PM
🔎New preprint!
We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture.
Big thanks to @ivanagasic.bsky.social and team!
Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5)
www.biorxiv.org/content/10.1...
We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture.
Big thanks to @ivanagasic.bsky.social and team!
Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5)
www.biorxiv.org/content/10.1...
Reposted by Joshua Tran
I am so proud of @jezcarlton.bsky.social . What a magnificent inaugural lecture, many congratulations Professor Carlton!
July 16, 2025 at 10:14 PM
I am so proud of @jezcarlton.bsky.social . What a magnificent inaugural lecture, many congratulations Professor Carlton!
Reposted by Joshua Tran
Check our latest methods chapter on how to use Dictyostelium–Mycobacterium marinum as a high-throughput screening platform for anti-infective compounds 👇
www.frontiersin.org/journals/mic...
@nabilhanna3.bsky.social
www.frontiersin.org/journals/mic...
@nabilhanna3.bsky.social
Frontiers | Dictyosteliumdiscoideum–Mycobacterium marinum infection model: a powerful high-throughput screening platform for anti-infective compounds
Tuberculosis is among the world’s deadliest diseases, causing approximately 2 million deaths annually. The urgent need for new antitubercular drugs has been ...
www.frontiersin.org
July 4, 2025 at 11:26 AM
Check our latest methods chapter on how to use Dictyostelium–Mycobacterium marinum as a high-throughput screening platform for anti-infective compounds 👇
www.frontiersin.org/journals/mic...
@nabilhanna3.bsky.social
www.frontiersin.org/journals/mic...
@nabilhanna3.bsky.social
It was a great pleasure to host @lizmillercu.bsky.social here in Geneva on behalf of the PhD Association!
Phenomenal science. Engaging discussions. And plenty of laughs along the way. What more can you ask for?
Thanks, Liz, for such an insightful and fun visit!
Phenomenal science. Engaging discussions. And plenty of laughs along the way. What more can you ask for?
Thanks, Liz, for such an insightful and fun visit!
July 1, 2025 at 8:17 PM
It was a great pleasure to host @lizmillercu.bsky.social here in Geneva on behalf of the PhD Association!
Phenomenal science. Engaging discussions. And plenty of laughs along the way. What more can you ask for?
Thanks, Liz, for such an insightful and fun visit!
Phenomenal science. Engaging discussions. And plenty of laughs along the way. What more can you ask for?
Thanks, Liz, for such an insightful and fun visit!
Reposted by Joshua Tran
What a fantastic ESCRT meeting, the field is going strong and full of exciting science. Many thanks to @rouxlab.bsky.social @cellarchlab.com @jujumathieu.bsky.social @magromayor.bsky.social @majarad.bsky.social for organising such a a great event
June 27, 2025 at 12:59 PM
What a fantastic ESCRT meeting, the field is going strong and full of exciting science. Many thanks to @rouxlab.bsky.social @cellarchlab.com @jujumathieu.bsky.social @magromayor.bsky.social @majarad.bsky.social for organising such a a great event
Reposted by Joshua Tran
#YeastNomenclature reminder: Protein Name Format
#Yeast proteins are referred to by the relevant gene symbol, non-italic, initial letter uppercase and with the suffix ‘p’ (for example, Ade5p). The suffix can be omitted if the word 'protein' is appended (for example, the Ade5 protein).
#Yeast proteins are referred to by the relevant gene symbol, non-italic, initial letter uppercase and with the suffix ‘p’ (for example, Ade5p). The suffix can be omitted if the word 'protein' is appended (for example, the Ade5 protein).
June 26, 2025 at 6:57 PM
#YeastNomenclature reminder: Protein Name Format
#Yeast proteins are referred to by the relevant gene symbol, non-italic, initial letter uppercase and with the suffix ‘p’ (for example, Ade5p). The suffix can be omitted if the word 'protein' is appended (for example, the Ade5 protein).
#Yeast proteins are referred to by the relevant gene symbol, non-italic, initial letter uppercase and with the suffix ‘p’ (for example, Ade5p). The suffix can be omitted if the word 'protein' is appended (for example, the Ade5 protein).
Reposted by Joshua Tran
How do cells switch on the actin assembly at endocytic sites? How can this on-switch evolve? Check out our new preprint!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
June 24, 2025 at 7:22 PM
How do cells switch on the actin assembly at endocytic sites? How can this on-switch evolve? Check out our new preprint!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Joshua Tran
Justin Krish Williams, Randy Schekman et al. @ucberkeleyofficial.bsky.social show that human cells shed extracellular vesicles in order to repair their membranes. rupress.org/jcb/article/...
#EVs #Exosomes
#EVs #Exosomes
May 16, 2025 at 4:16 PM
Justin Krish Williams, Randy Schekman et al. @ucberkeleyofficial.bsky.social show that human cells shed extracellular vesicles in order to repair their membranes. rupress.org/jcb/article/...
#EVs #Exosomes
#EVs #Exosomes
Reposted by Joshua Tran
🤩 Last week I successfully defended my PhD!
It was such a special day, made even better by having friends, family, and colleagues there with me. Thanks for all the support and kind words!
Huge thanks to my jury members for the thoughtful feedback and conversations.
@soldatilab.bsky.social
It was such a special day, made even better by having friends, family, and colleagues there with me. Thanks for all the support and kind words!
Huge thanks to my jury members for the thoughtful feedback and conversations.
@soldatilab.bsky.social
June 17, 2025 at 1:59 PM
🤩 Last week I successfully defended my PhD!
It was such a special day, made even better by having friends, family, and colleagues there with me. Thanks for all the support and kind words!
Huge thanks to my jury members for the thoughtful feedback and conversations.
@soldatilab.bsky.social
It was such a special day, made even better by having friends, family, and colleagues there with me. Thanks for all the support and kind words!
Huge thanks to my jury members for the thoughtful feedback and conversations.
@soldatilab.bsky.social
What a conference! It was such a great pleasure to share my research & discuss with amazing cell biologists from all parts of the world at #CellBio2024 . I am inspired by the community & grateful for all the amazing interactions. Looking forward to next time!
@ascbiology.bsky.social
@ascbiology.bsky.social
December 19, 2024 at 11:25 PM
What a conference! It was such a great pleasure to share my research & discuss with amazing cell biologists from all parts of the world at #CellBio2024 . I am inspired by the community & grateful for all the amazing interactions. Looking forward to next time!
@ascbiology.bsky.social
@ascbiology.bsky.social
Don’t miss out on TODAY’S session, “Surfing the Surface: Navigating the waves of Membrane Dynamics” at the @ascbiology.bsky.social EMBO #CellBio2024 ! Join us for fascinating talks in Room 30C at 8h45.
#CellBio24
#CellBio24
December 17, 2024 at 4:17 PM
Don’t miss out on TODAY’S session, “Surfing the Surface: Navigating the waves of Membrane Dynamics” at the @ascbiology.bsky.social EMBO #CellBio2024 ! Join us for fascinating talks in Room 30C at 8h45.
#CellBio24
#CellBio24
It was a great pleasure to present my work at the In Vitro Organelles Subgroup at #CellBio2024 ! Many thanks to the organizers and everyone who came!
I have my poster, B163, on Tuesday, the 17th at 11h15, to discuss more about membrane bending!
@ascbiology.bsky.social
@rouxlab.bsky.social
I have my poster, B163, on Tuesday, the 17th at 11h15, to discuss more about membrane bending!
@ascbiology.bsky.social
@rouxlab.bsky.social
December 16, 2024 at 2:40 AM
It was a great pleasure to present my work at the In Vitro Organelles Subgroup at #CellBio2024 ! Many thanks to the organizers and everyone who came!
I have my poster, B163, on Tuesday, the 17th at 11h15, to discuss more about membrane bending!
@ascbiology.bsky.social
@rouxlab.bsky.social
I have my poster, B163, on Tuesday, the 17th at 11h15, to discuss more about membrane bending!
@ascbiology.bsky.social
@rouxlab.bsky.social
I am pleased to be sharing my work in the @rouxlab.bsky.social at ASCB & EMBO Cell Bio 2024!
If you’re interested in membrane bending, crowding, curvature and of course the ESCRT machinery, pass by my talk on Saturday, Dec. 14th and/or my poster on Tuesday, Dec. 17th!
#CellBio2024
If you’re interested in membrane bending, crowding, curvature and of course the ESCRT machinery, pass by my talk on Saturday, Dec. 14th and/or my poster on Tuesday, Dec. 17th!
#CellBio2024
December 10, 2024 at 3:37 PM
I am pleased to be sharing my work in the @rouxlab.bsky.social at ASCB & EMBO Cell Bio 2024!
If you’re interested in membrane bending, crowding, curvature and of course the ESCRT machinery, pass by my talk on Saturday, Dec. 14th and/or my poster on Tuesday, Dec. 17th!
#CellBio2024
If you’re interested in membrane bending, crowding, curvature and of course the ESCRT machinery, pass by my talk on Saturday, Dec. 14th and/or my poster on Tuesday, Dec. 17th!
#CellBio2024
🚨 For all membrane dynamics and trafficking enthusiasts attending ASCB|EMBO #CellBio2024!
I will be chairing the session “Surfing the Surface: Navigating the Waves of Membrane Dynamics” on Tuesday, Dec. 17 at 08h45 in Room 30C.
Come join for these amazing talks!
I will be chairing the session “Surfing the Surface: Navigating the Waves of Membrane Dynamics” on Tuesday, Dec. 17 at 08h45 in Room 30C.
Come join for these amazing talks!
December 10, 2024 at 3:32 PM
🚨 For all membrane dynamics and trafficking enthusiasts attending ASCB|EMBO #CellBio2024!
I will be chairing the session “Surfing the Surface: Navigating the Waves of Membrane Dynamics” on Tuesday, Dec. 17 at 08h45 in Room 30C.
Come join for these amazing talks!
I will be chairing the session “Surfing the Surface: Navigating the Waves of Membrane Dynamics” on Tuesday, Dec. 17 at 08h45 in Room 30C.
Come join for these amazing talks!
Reposted by Joshua Tran
Hi all! 👋 I’m Oriol, PhD student at
@rouxlab.bsky.social , studying how forces impact stem cell behavior and development. Excited to connect and discuss science!!
#Biophysics #StemCells #DevelopmentalBiology
@rouxlab.bsky.social , studying how forces impact stem cell behavior and development. Excited to connect and discuss science!!
#Biophysics #StemCells #DevelopmentalBiology
December 3, 2024 at 5:42 PM
Hi all! 👋 I’m Oriol, PhD student at
@rouxlab.bsky.social , studying how forces impact stem cell behavior and development. Excited to connect and discuss science!!
#Biophysics #StemCells #DevelopmentalBiology
@rouxlab.bsky.social , studying how forces impact stem cell behavior and development. Excited to connect and discuss science!!
#Biophysics #StemCells #DevelopmentalBiology
Great talk by Roberto Zoncu from @ucberkeleyofficial.bsky.social on lysosomal integrity and repair hosted by @rouxlab.bsky.social ! I had the pleasure of taking MCB 100B with Roberto during my studies and it was so nice to see the phenomenal research being done!
December 3, 2024 at 7:31 AM
Great talk by Roberto Zoncu from @ucberkeleyofficial.bsky.social on lysosomal integrity and repair hosted by @rouxlab.bsky.social ! I had the pleasure of taking MCB 100B with Roberto during my studies and it was so nice to see the phenomenal research being done!
Reposted by Joshua Tran
Hey everyone! Just joined Bluesky! 👋
I’m a postdoc at @rouxlab.bsky.social, working with minimal reconstituted in vitro systems to study the mechanical properties of membranes and how they undergo remodeling.
Expect posts mostly about science, with some curiosity and fun sprinkled in. Let’s connect!
I’m a postdoc at @rouxlab.bsky.social, working with minimal reconstituted in vitro systems to study the mechanical properties of membranes and how they undergo remodeling.
Expect posts mostly about science, with some curiosity and fun sprinkled in. Let’s connect!
November 25, 2024 at 2:52 PM
Hey everyone! Just joined Bluesky! 👋
I’m a postdoc at @rouxlab.bsky.social, working with minimal reconstituted in vitro systems to study the mechanical properties of membranes and how they undergo remodeling.
Expect posts mostly about science, with some curiosity and fun sprinkled in. Let’s connect!
I’m a postdoc at @rouxlab.bsky.social, working with minimal reconstituted in vitro systems to study the mechanical properties of membranes and how they undergo remodeling.
Expect posts mostly about science, with some curiosity and fun sprinkled in. Let’s connect!